JP2023509793A5 - - Google Patents
Info
- Publication number
- JP2023509793A5 JP2023509793A5 JP2022542364A JP2022542364A JP2023509793A5 JP 2023509793 A5 JP2023509793 A5 JP 2023509793A5 JP 2022542364 A JP2022542364 A JP 2022542364A JP 2022542364 A JP2022542364 A JP 2022542364A JP 2023509793 A5 JP2023509793 A5 JP 2023509793A5
- Authority
- JP
- Japan
- Prior art keywords
- cdr
- seq
- optionally
- complex according
- nucleoside
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062959776P | 2020-01-10 | 2020-01-10 | |
| US62/959,776 | 2020-01-10 | ||
| US202062965712P | 2020-01-24 | 2020-01-24 | |
| US62/965,712 | 2020-01-24 | ||
| US202062968383P | 2020-01-31 | 2020-01-31 | |
| US62/968,383 | 2020-01-31 | ||
| US202063055499P | 2020-07-23 | 2020-07-23 | |
| US63/055,499 | 2020-07-23 | ||
| US202063069063P | 2020-08-23 | 2020-08-23 | |
| US63/069,063 | 2020-08-23 | ||
| US202063132856P | 2020-12-31 | 2020-12-31 | |
| US63/132,856 | 2020-12-31 | ||
| PCT/US2021/012667 WO2021142234A1 (en) | 2020-01-10 | 2021-01-08 | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023509793A JP2023509793A (ja) | 2023-03-09 |
| JP2023509793A5 true JP2023509793A5 (https=) | 2024-01-17 |
| JP7829488B2 JP7829488B2 (ja) | 2026-03-13 |
Family
ID=76788870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022542364A Active JP7829488B2 (ja) | 2020-01-10 | 2021-01-08 | 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230144436A1 (https=) |
| EP (1) | EP4087653A4 (https=) |
| JP (1) | JP7829488B2 (https=) |
| KR (1) | KR20220125800A (https=) |
| CN (1) | CN115427108A (https=) |
| AU (1) | AU2021206234A1 (https=) |
| BR (1) | BR112022013686A2 (https=) |
| CA (1) | CA3163295A1 (https=) |
| IL (1) | IL294479A (https=) |
| MX (1) | MX2022008533A (https=) |
| WO (1) | WO2021142234A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3108282A1 (en) | 2018-08-02 | 2020-02-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| SG11202100928QA (en) | 2018-08-02 | 2021-02-25 | Dyne Therapeutics Inc | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| JP7780691B2 (ja) * | 2020-01-10 | 2025-12-05 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 |
| CA3202832A1 (en) * | 2020-12-31 | 2022-07-07 | Romesh R. Subramanian | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11672872B2 (en) | 2021-07-09 | 2023-06-13 | Dyne Therapeutics, Inc. | Anti-transferrin receptor antibody and uses thereof |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| JP2024525608A (ja) | 2021-07-09 | 2024-07-12 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体および製剤 |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| US11633498B2 (en) | 2021-07-09 | 2023-04-25 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| WO2023034409A1 (en) | 2021-09-01 | 2023-03-09 | Biogen Ma Inc. | Anti-transferrin receptor antibodies and uses thereof |
| WO2023034870A2 (en) | 2021-09-01 | 2023-03-09 | Ionis Pharmaceuticals, Inc. | Compounds and methods for reducing dmpk expression |
| EP4401777A4 (en) * | 2021-09-16 | 2025-08-13 | Dyne Therapeutics Inc | DOSAGE OF MUSCLE-TARGETING COMPLEXES TO TREAT DYSTROPHINOPATHIES |
| WO2023086864A1 (en) * | 2021-11-12 | 2023-05-19 | Dyne Therapeutics, Inc. | Muscle targeting complexes for treating facioscapulohumeral muscular dystrophy |
| IL316143A (en) | 2022-04-15 | 2024-12-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of myotonic dystrophy |
| WO2024257848A1 (ja) * | 2023-06-16 | 2024-12-19 | ルクサナバイオテク株式会社 | 遅発性中枢毒性が低減されているアンチセンスオリゴヌクレオチドの設計方法、及びその製造方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1461359T1 (sl) * | 2002-01-18 | 2007-06-30 | Pf Medicament | Nova anti IGF-IR protitelesa in njihova uporaba |
| US20100016215A1 (en) * | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| BR112014020826A8 (pt) * | 2012-02-24 | 2017-09-19 | Stem Centrx Inc | Anticorpo que se liga especificamente a um epítopo, ácido nucleico, vetor ou célula hospedeira, conjugado de fármaco anticorpo, composição farmacêutica compreendendo o referido anticorpo, uso do mesmo, kit e método de preparação do conjugado |
| CA2907072A1 (en) * | 2012-03-16 | 2013-09-19 | Valerion Therapeutics, Llc | Antisense conjugates for decreasing expression of dmpk |
| WO2014096015A1 (en) * | 2012-12-21 | 2014-06-26 | F. Hoffmann-La Roche Ag | Disulfide-linked multivalent mhc class i comprising multi-function proteins |
| EA035419B9 (ru) * | 2014-05-29 | 2020-08-07 | Мэкроудженикс, Инк. | Триспецифичные связывающие молекулы и способы их применения |
| JP2018528783A (ja) * | 2015-09-25 | 2018-10-04 | アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | コンジュゲートアンチセンス化合物及びその使用 |
| DK3473270T5 (da) * | 2016-06-20 | 2024-09-09 | Genahead Bio Inc | Konjugat af antistof-lægemiddel |
| KR102497564B1 (ko) * | 2016-12-26 | 2023-02-07 | 제이씨알 파마 가부시키가이샤 | 혈액뇌관문을 통과하는 신규한 항인간 트랜스페린 수용체 항체 |
| AU2018378812B2 (en) * | 2017-12-06 | 2025-05-22 | Avidity Biosciences, Inc. | Compositions and methods of treating muscle atrophy and myotonic dystrophy |
| IL280536B2 (en) * | 2018-08-02 | 2024-12-01 | Dyne Therapeutics Inc | Complexes targeting transferrin receptor and uses thereof |
| KR20220125801A (ko) * | 2020-01-10 | 2022-09-14 | 다인 세라퓨틱스, 인크. | 근육 표적화 복합체 및 안면견갑상완 근육 이영양증을 치료하기 위한 그의 용도 |
| CA3163283A1 (en) * | 2020-01-10 | 2021-07-15 | Romesh R. Subramanian | Muscle targeting complexes and uses thereof for modulation of genes associated with muscle health |
| JP7780691B2 (ja) * | 2020-01-10 | 2025-12-05 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 |
| CA3163608A1 (en) * | 2020-01-10 | 2021-07-15 | Romesh R. Subramanian | Muscle-targeting complexes and uses thereof |
| US20230117883A1 (en) * | 2020-01-24 | 2023-04-20 | Dyne Therapeutics, Inc. | Muscle-targeting complexes and uses thereof in treating muscle atrophy |
| CN115427059A (zh) * | 2020-01-31 | 2022-12-02 | 达因疗法公司 | 抗转铁蛋白受体（tfr）抗体及其用途 |
-
2021
- 2021-01-08 AU AU2021206234A patent/AU2021206234A1/en active Pending
- 2021-01-08 CA CA3163295A patent/CA3163295A1/en active Pending
- 2021-01-08 US US17/791,681 patent/US20230144436A1/en active Pending
- 2021-01-08 CN CN202180019691.8A patent/CN115427108A/zh active Pending
- 2021-01-08 EP EP21738259.7A patent/EP4087653A4/en active Pending
- 2021-01-08 WO PCT/US2021/012667 patent/WO2021142234A1/en not_active Ceased
- 2021-01-08 BR BR112022013686A patent/BR112022013686A2/pt unknown
- 2021-01-08 JP JP2022542364A patent/JP7829488B2/ja active Active
- 2021-01-08 IL IL294479A patent/IL294479A/en unknown
- 2021-01-08 MX MX2022008533A patent/MX2022008533A/es unknown
- 2021-01-08 KR KR1020227027136A patent/KR20220125800A/ko active Pending
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