JP2024525611A5 - - Google Patents

Info

Publication number
JP2024525611A5
JP2024525611A5 JP2024500479A JP2024500479A JP2024525611A5 JP 2024525611 A5 JP2024525611 A5 JP 2024525611A5 JP 2024500479 A JP2024500479 A JP 2024500479A JP 2024500479 A JP2024500479 A JP 2024500479A JP 2024525611 A5 JP2024525611 A5 JP 2024525611A5
Authority
JP
Japan
Prior art keywords
seq
oligonucleotide
optionally
complex according
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500479A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525611A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/073527 external-priority patent/WO2023283613A1/en
Publication of JP2024525611A publication Critical patent/JP2024525611A/ja
Publication of JP2024525611A5 publication Critical patent/JP2024525611A5/ja
Pending legal-status Critical Current

Links

JP2024500479A 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用 Pending JP2024525611A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163219999P 2021-07-09 2021-07-09
US63/219,999 2021-07-09
PCT/US2022/073527 WO2023283613A1 (en) 2021-07-09 2022-07-08 Muscle targeting complexes and uses thereof for treating dystrophinopathies

Publications (2)

Publication Number Publication Date
JP2024525611A JP2024525611A (ja) 2024-07-12
JP2024525611A5 true JP2024525611A5 (https=) 2025-07-16

Family

ID=84802088

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500479A Pending JP2024525611A (ja) 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用

Country Status (10)

Country Link
US (1) US20240318176A1 (https=)
EP (1) EP4367147A4 (https=)
JP (1) JP2024525611A (https=)
KR (1) KR20240032945A (https=)
CN (1) CN118355035A (https=)
AU (1) AU2022307086A1 (https=)
CA (1) CA3226365A1 (https=)
IL (1) IL309937A (https=)
MX (1) MX2024000494A (https=)
WO (1) WO2023283613A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
JP2024525608A (ja) 2021-07-09 2024-07-12 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体および製剤
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
IL316143A (en) 2022-04-15 2024-12-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of myotonic dystrophy
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
WO2025160275A1 (en) 2024-01-24 2025-07-31 Arrowhead Pharmaceuticals, Inc. Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
WO2005058244A2 (en) * 2003-12-15 2005-06-30 Alexion Pharmaceuticals, Inc. Novel anti-dc-sign antibodies
WO2008073300A2 (en) * 2006-12-08 2008-06-19 Lexicon Pharmaceuticals, Inc. Monoclonal antibodies against angptl3
BR112013014527A2 (pt) * 2010-12-20 2017-03-07 Genentech Inc anticorpo isolado, ácido nucleico isolado, célula hospedeira, método para produzir um anticorpo, imunoconjugado, formulação farmacêutica, uso do imunoconjugado, método para tratamento de um indivíduo que tem um câncer positivo para mesotelina, para inibição de proliferação de uma célula positiva para mesotelina, para detecção de mesotelina humana em uma amostra biológica e para detectar um câncer positivo para mesotelina
RU2014109038A (ru) * 2011-08-23 2015-09-27 Рош Гликарт Аг Антитела к хондроитинсульфат протеогликану меланомы
CA2861247C (en) * 2011-12-28 2021-11-16 Nippon Shinyaku Co., Ltd. Antisense nucleic acids
AR099625A1 (es) * 2014-03-21 2016-08-03 Lilly Co Eli Anticuerpos de il-21
JP7015244B2 (ja) * 2016-03-22 2022-02-02 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト プロテアーゼ活性化t細胞二重特異性分子
MX2020003130A (es) * 2017-09-22 2020-09-25 Avidity Biosciences Inc Composiciones y metodos de induccion de salto de exon en acidos nucleicos-polipeptidos.
CA3108282A1 (en) * 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL280536B2 (en) * 2018-08-02 2024-12-01 Dyne Therapeutics Inc Complexes targeting transferrin receptor and uses thereof
WO2020219820A1 (en) * 2019-04-25 2020-10-29 Avidity Biosciences, Inc. Nucleic acid compositions and methods of multi-exon skipping
CA3163608A1 (en) * 2020-01-10 2021-07-15 Romesh R. Subramanian Muscle-targeting complexes and uses thereof
JP7780691B2 (ja) * 2020-01-10 2025-12-05 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用
MX2023000984A (es) * 2020-07-23 2023-05-03 Dyne Therapeutics Inc Complejos dirigidos al musculo y usos de los mismos para el tratamiento de distrofinopatias.

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