JP2024059609A5 - - Google Patents
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- JP2024059609A5 JP2024059609A5 JP2023214174A JP2023214174A JP2024059609A5 JP 2024059609 A5 JP2024059609 A5 JP 2024059609A5 JP 2023214174 A JP2023214174 A JP 2023214174A JP 2023214174 A JP2023214174 A JP 2023214174A JP 2024059609 A5 JP2024059609 A5 JP 2024059609A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- antigen
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063051172P | 2020-07-13 | 2020-07-13 | |
| US63/051,172 | 2020-07-13 | ||
| US202163154531P | 2021-02-26 | 2021-02-26 | |
| US63/154,531 | 2021-02-26 | ||
| JP2023501559A JP2023534437A (ja) | 2020-07-13 | 2021-07-12 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
| PCT/US2021/041304 WO2022015656A1 (en) | 2020-07-13 | 2021-07-12 | Camptothecin analogs conjugated to a glutamine residue in a protein, and their use |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023501559A Division JP2023534437A (ja) | 2020-07-13 | 2021-07-12 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024059609A JP2024059609A (ja) | 2024-05-01 |
| JP2024059609A5 true JP2024059609A5 (enExample) | 2024-07-23 |
| JP7776485B2 JP7776485B2 (ja) | 2025-11-26 |
Family
ID=77168491
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023501559A Pending JP2023534437A (ja) | 2020-07-13 | 2021-07-12 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
| JP2023214174A Active JP7776485B2 (ja) | 2020-07-13 | 2023-12-19 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023501559A Pending JP2023534437A (ja) | 2020-07-13 | 2021-07-12 | タンパク質中のグルタミン残基にコンジュゲートされたカンプトテシンアナログおよびその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20220072141A1 (enExample) |
| EP (2) | EP4406608A3 (enExample) |
| JP (2) | JP2023534437A (enExample) |
| KR (2) | KR20230038738A (enExample) |
| CN (2) | CN116390771A (enExample) |
| AU (2) | AU2021308190A1 (enExample) |
| BR (1) | BR112023000489A2 (enExample) |
| CA (1) | CA3183184A1 (enExample) |
| CL (1) | CL2023000098A1 (enExample) |
| CO (1) | CO2023001402A2 (enExample) |
| IL (2) | IL299153A (enExample) |
| MA (1) | MA71650A (enExample) |
| MX (2) | MX2023000544A (enExample) |
| WO (1) | WO2022015656A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021148500A1 (en) * | 2020-01-22 | 2021-07-29 | Medimmune Limited | Compounds and conjugates thereof |
| CN115175705A (zh) * | 2020-09-30 | 2022-10-11 | 映恩生物制药（苏州）有限公司 | 一种抗肿瘤化合物及其制备方法和应用 |
| JP2025502147A (ja) * | 2022-01-12 | 2025-01-24 | リジェネロン ファーマシューティカルズ，インク． | タンパク質中のグルタミン残基にコンジュゲートしたカンプトテシンアナログおよびその使用 |
| WO2023138682A1 (zh) * | 2022-01-24 | 2023-07-27 | 北京桦冠生物技术有限公司 | 缀合物及其用途 |
| KR20240155334A (ko) * | 2022-03-09 | 2024-10-28 | 메르크 파텐트 게엠베하 | 항-gd2 항체, 면역접합체 및 그의 치료적 용도 |
| TW202344252A (zh) * | 2022-05-09 | 2023-11-16 | 大陸商同宜醫藥（蘇州）有限公司 | 一種喜樹鹼衍生物，基於其的抗體－藥物偶聯物和藥物組成物，及其應用 |
| CN118955614A (zh) * | 2022-07-05 | 2024-11-15 | 上海药明合联生物技术有限公司 | 偶联连接子 |
| EP4561636A1 (en) | 2022-07-29 | 2025-06-04 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle |
| AU2023349279A1 (en) * | 2022-09-30 | 2025-05-15 | Beone Medicines I Gmbh | Ligand-drug conjugate of exatecan analogue, and medical use thereof |
| CN120500498A (zh) | 2022-11-14 | 2025-08-15 | 瑞泽恩制药公司 | 用于成纤维细胞生长因子受体3介导的至星形胶质细胞的递送的组合物及方法 |
| KR20250133813A (ko) | 2022-12-21 | 2025-09-08 | 리제너론 파마슈티칼스 인코포레이티드 | Adc 접합을 위한 토포이소머라아제 i 억제제의 전구약물 및 이의 사용 방법 |
| WO2024168199A1 (en) | 2023-02-09 | 2024-08-15 | Regeneron Pharmaceuticals, Inc. | Antibody-drug conjugates via inverse electron demand diels-alder reactions |
| WO2025014533A1 (en) | 2023-07-10 | 2025-01-16 | Regeneron Pharmaceuticals, Inc. | Anti-human cacng1 antibody-drug conjugates and uses thereof |
| WO2025038752A1 (en) * | 2023-08-14 | 2025-02-20 | Cancer Targeted Technology Llc | Psma binding ligand-linker conjugates and methods for use thereof |
| EP4537854A1 (en) * | 2023-10-04 | 2025-04-16 | Formosa Laboratories, Inc. | Compound for conjugation, conjugate and pharmaceutical composition comprising the same |
| WO2025078841A2 (en) | 2023-10-11 | 2025-04-17 | Antikor Biopharma Limited | Antibodies, conjugates, and uses thereof |
| WO2025103474A1 (zh) * | 2023-11-17 | 2025-05-22 | 成都康弘生物科技有限公司 | 双毒素抗体药物偶联物及其用途 |
| WO2025199666A1 (en) * | 2024-03-25 | 2025-10-02 | Canwell Biotech Limited | Multivalent linkers for high loading antibody-drug conjugates, and compositions and methods thereof |
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| CA2008368C (en) | 1989-01-24 | 2003-04-08 | Jeffrey Greve | Soluble molecule related to but distinct from icam-1 |
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| CA2103059C (en) | 1991-06-14 | 2005-03-22 | Paul J. Carter | Method for making humanized antibodies |
| US5714586A (en) | 1995-06-07 | 1998-02-03 | American Cyanamid Company | Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates |
| US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US20070258987A1 (en) | 2000-11-28 | 2007-11-08 | Seattle Genetics, Inc. | Recombinant Anti-Cd30 Antibodies and Uses Thereof |
| WO2003087306A2 (en) | 2002-04-05 | 2003-10-23 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 98p4b6 useful in treatment and detection of cancer |
| WO2005079490A2 (en) | 2004-02-13 | 2005-09-01 | Nuvelo, Inc. | Methods of therapy and diagnosis using targeting of cells that express steap2 polypeptides |
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| BRPI0510883B8 (pt) | 2004-06-01 | 2021-05-25 | Genentech Inc | composto conjugado de droga e anticorpo, composição farmacêutica, método de fabricação de composto conjugado de droga e anticorpo e usos de uma formulação, de um conjugado de droga e anticorpo e um agente quimioterapêutico e de uma combinação |
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| WO2008122039A2 (en) | 2007-04-02 | 2008-10-09 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selenocysteine mediated hybrid antibody molecules |
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-
2021
- 2021-07-12 CA CA3183184A patent/CA3183184A1/en active Pending
- 2021-07-12 MA MA71650A patent/MA71650A/fr unknown
- 2021-07-12 WO PCT/US2021/041304 patent/WO2022015656A1/en not_active Ceased
- 2021-07-12 CN CN202180062762.2A patent/CN116390771A/zh active Pending
- 2021-07-12 KR KR1020237004637A patent/KR20230038738A/ko active Pending
- 2021-07-12 AU AU2021308190A patent/AU2021308190A1/en active Pending
- 2021-07-12 IL IL299153A patent/IL299153A/en unknown
- 2021-07-12 BR BR112023000489A patent/BR112023000489A2/pt unknown
- 2021-07-12 US US17/373,524 patent/US20220072141A1/en active Pending
- 2021-07-12 MX MX2023000544A patent/MX2023000544A/es unknown
- 2021-07-12 IL IL309173A patent/IL309173A/en unknown
- 2021-07-12 EP EP24176032.1A patent/EP4406608A3/en active Pending
- 2021-07-12 CN CN202410175152.9A patent/CN118085100A/zh active Pending
- 2021-07-12 KR KR1020247008244A patent/KR20240038138A/ko active Pending
- 2021-07-12 JP JP2023501559A patent/JP2023534437A/ja active Pending
- 2021-07-12 EP EP21749495.4A patent/EP4178625A1/en active Pending
-
2023
- 2023-01-10 MX MX2024003180A patent/MX2024003180A/es unknown
- 2023-01-10 CL CL2023000098A patent/CL2023000098A1/es unknown
- 2023-02-09 CO CONC2023/0001402A patent/CO2023001402A2/es unknown
- 2023-11-21 US US18/516,454 patent/US20240252661A1/en active Pending
- 2023-12-19 JP JP2023214174A patent/JP7776485B2/ja active Active
-
2024
- 2024-02-09 AU AU2024200822A patent/AU2024200822A1/en active Pending
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