JP2023547676A5 - - Google Patents

Info

Publication number
JP2023547676A5
JP2023547676A5 JP2023527079A JP2023527079A JP2023547676A5 JP 2023547676 A5 JP2023547676 A5 JP 2023547676A5 JP 2023527079 A JP2023527079 A JP 2023527079A JP 2023527079 A JP2023527079 A JP 2023527079A JP 2023547676 A5 JP2023547676 A5 JP 2023547676A5
Authority
JP
Japan
Prior art keywords
dna vector
propionibacterium acnes
manipulated
phage
vector according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023527079A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023547676A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/080667 external-priority patent/WO2022096590A1/en
Publication of JP2023547676A publication Critical patent/JP2023547676A/ja
Publication of JP2023547676A5 publication Critical patent/JP2023547676A5/ja
Pending legal-status Critical Current

Links

JP2023527079A 2020-11-04 2021-11-04 DNAペイロードをアクネ菌集団へとin situ送達するためのファージ由来粒子 Pending JP2023547676A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063109834P 2020-11-04 2020-11-04
US202063109832P 2020-11-04 2020-11-04
US63/109,834 2020-11-04
US63/109,832 2020-11-04
US202163145969P 2021-02-04 2021-02-04
US202163145967P 2021-02-04 2021-02-04
US63/145,969 2021-02-04
US63/145,967 2021-02-04
PCT/EP2021/080667 WO2022096590A1 (en) 2020-11-04 2021-11-04 Phage-derived particles for in situ delivery of dna payload into c. acnes population

Publications (2)

Publication Number Publication Date
JP2023547676A JP2023547676A (ja) 2023-11-13
JP2023547676A5 true JP2023547676A5 (https=) 2024-11-06

Family

ID=78621842

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023527081A Pending JP2023547677A (ja) 2020-11-04 2021-11-04 キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用
JP2023527079A Pending JP2023547676A (ja) 2020-11-04 2021-11-04 DNAペイロードをアクネ菌集団へとin situ送達するためのファージ由来粒子

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2023527081A Pending JP2023547677A (ja) 2020-11-04 2021-11-04 キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用

Country Status (7)

Country Link
US (7) US11473093B2 (https=)
EP (2) EP4240841A1 (https=)
JP (2) JP2023547677A (https=)
KR (2) KR20230098825A (https=)
CA (2) CA3198924A1 (https=)
IL (2) IL302448A (https=)
WO (2) WO2022096596A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US12533312B2 (en) 2011-02-04 2026-01-27 Seed Health, Inc. Method and system for preventing sore throat in humans
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US10760075B2 (en) 2018-04-30 2020-09-01 Snipr Biome Aps Treating and preventing microbial infections
JP2023547677A (ja) 2020-11-04 2023-11-13 エリゴ・バイオサイエンス キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用
US11739304B2 (en) * 2021-05-12 2023-08-29 Eligo Bioscience Production of lytic phages
EP4583895A1 (en) * 2022-09-06 2025-07-16 Trobix Bio Ltd Systems for production of transducing particles, methods, kits, compositions and uses thereof
WO2025089839A1 (ko) * 2023-10-24 2025-05-01 중앙대학교 산학협력단 Crispr-cas 탑재 박테리오파지 및 이의 용도

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037026A1 (en) 1996-04-02 1997-10-09 Smithkline Beecham Corporation Novel compounds
JP2000512487A (ja) 1996-05-14 2000-09-26 スミスクライン・ビーチャム・コーポレイション 新規化合物
JP4469026B2 (ja) 1996-10-31 2010-05-26 ヒューマン ジノーム サイエンシーズ,インコーポレイテッド Streptococcus pneumoniaeの抗原およびワクチン
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
CA2671261A1 (en) 1997-11-06 1999-05-20 Novartis Vaccines And Diagnostics S.R.L. Neisserial antigens
EP1034277B1 (en) 1997-11-26 2012-06-27 Inhibitex, Inc. Extracellular matrix-binding proteins from Staphylococcus aureus
EP1047784B2 (en) 1998-01-14 2015-03-18 Novartis Vaccines and Diagnostics S.r.l. Neissera meningitidis antigens
WO1999053940A1 (en) 1998-04-23 1999-10-28 Uab Research Foundation PNEUMOCOCCAL SURFACE PROTEIN C(PspC), EPITOPIC REGIONS AND STRAIN SELECTION THEREOF, AND USES THEREFOR
EP2261338A3 (en) 1998-05-01 2012-01-04 Novartis Vaccines and Diagnostics, Inc. Neisseria meningitidis antigens and compositions
GB9810193D0 (en) 1998-05-12 1998-07-08 Smithkline Beecham Biolog Novel compounds
CN1318103A (zh) 1998-07-27 2001-10-17 微生物技术有限公司 肺炎链球菌的核酸和蛋白质
ATE361365T1 (de) 1998-07-27 2007-05-15 Sanofi Pasteur Ltd Streptococcus pneumoniae proteine und nukleinsäuren
ES2322409T3 (es) 1998-08-31 2009-06-19 Inhibitex, Inc. Vacunas multicomponentes contra staphylococcus aureus.
JP4714342B2 (ja) 1998-08-31 2011-06-29 ザ プラヴアスト フエロウス アンド スカラース オブ ザ カレツヂ オブ ザ ハリー アンド アンデイヴアイデツド トリニテイ オブ クイーン エリザベス ニヤー ダブリン コアグラーゼ陰性スタフィロコカス菌に由来のポリペプチド及びポリヌクレオチド
GB9828000D0 (en) 1998-12-18 1999-02-10 Chiron Spa Antigens
EP1140157B1 (en) 1998-12-21 2009-02-18 MedImmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
CN1198932C (zh) 1999-03-26 2005-04-27 科特克斯(Om)有限公司 肺炎链球菌抗原
JP2003501110A (ja) 1999-06-10 2003-01-14 メディミューン,インコーポレーテッド 肺炎連鎖球菌タンパク質とワクチン
EP1075841A1 (en) 1999-08-13 2001-02-14 Erasmus Universiteit Rotterdam Pneumococcal vaccines
CA2404260A1 (en) 2000-03-21 2001-09-27 Elitra Pharmaceuticals, Inc. Identification of essential genes in prokaryotes
JP2003530872A (ja) 2000-04-27 2003-10-21 メディミューン,インコーポレイテッド 免疫原肺炎連鎖球菌タンパク質とそのワクチン組成物
JP2004502415A (ja) 2000-07-03 2004-01-29 カイロン エセ.ピー.アー. Chlamydiapneumoniaeに対する免疫化
US20040091495A1 (en) 2000-07-20 2004-05-13 Lars Bjorck Protein
AU8743001A (en) 2000-08-28 2002-03-13 Aventis Pasteur Moraxella polypeptides and corresponding dna fragments and uses thereof
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
CA2426738A1 (en) 2000-10-26 2002-05-02 David William Holden Streptococcal genes
CA2881568C (en) 2000-10-27 2019-09-24 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from streptococcus groups a & b
AT410798B (de) 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
GB0103424D0 (en) 2001-02-12 2001-03-28 Chiron Spa Gonococcus proteins
AU2002306849A1 (en) 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0108079D0 (en) 2001-03-30 2001-05-23 Microbial Technics Ltd Protein
WO2002094851A2 (en) 2001-05-18 2002-11-28 The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Healthand Human Services, Centers For Disease Control And Prevention, Technology Transfer Office Peptide vaccines against group a streptococci
MXPA03011701A (es) 2001-06-15 2004-12-06 Nhibitex Inc Anticuerpos monoclonales y policlonales de reaccion que reconocen las proteinas de superficie a partir de estafilococos coagulasa-negativos y staphylococcus aureus.
ATE542829T1 (de) 2001-08-02 2012-02-15 Univ Sheffield Impfstoff
RU2331435C2 (ru) 2001-12-12 2008-08-20 Чирон Срл. Иммунизация против chlamydia trachomatis
GB0203403D0 (en) 2002-02-13 2002-04-03 Chiron Spa Chlamydia cytotoxic-T cell epitopes
EP2275122A3 (en) 2002-04-02 2011-05-18 Ben Gurion University Of The Negev Research And Development Authority Protein-based streptococcus pneumoniae vaccines
GB0210128D0 (en) 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
KR20050010040A (ko) 2002-06-11 2005-01-26 글락소스미스클라인 바이오로지칼즈 에스.에이. 면역원성 조성물
ES2504166T3 (es) 2002-09-13 2014-10-08 Novartis Vaccines And Diagnostics, Inc. Vacuna de estreptococo del grupo B
ES2529736T3 (es) 2003-04-10 2015-02-25 Novartis Vaccines And Diagnostics, Inc. Composición inmunogénica que comprende una proteína espicular del coronavirus del SARS
EP2311988A1 (en) 2003-04-15 2011-04-20 Intercell AG S. pneumoniae antigens
MXPA05013260A (es) 2003-06-26 2006-03-09 Chiron Corp Composiciones inmunogenicas para chlamydia trachomatis.
ES2505695T3 (es) 2003-07-31 2014-10-10 Novartis Vaccines And Diagnostics, Inc. Composiciones inmunógenas para Streptococcus pyogenes
US20070134263A1 (en) 2004-02-18 2007-06-14 Anderson Annaliesa S Polypeptides for inducing a protective immune response against staphyloococcus aureus
NZ553776A (en) 2004-09-22 2010-05-28 Glaxosmithkline Biolog Sa Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide.
JP5127708B2 (ja) * 2005-07-12 2013-01-23 マイクレオス べスローテン フェンノートシャップ バクテリオファージ及びその使用
US7442511B2 (en) 2005-12-27 2008-10-28 Obetech, Llc Adipogenic adenoviruses as a biomarker for disease
AU2007281934B2 (en) 2006-01-18 2012-11-15 University Of Chicago Compositions and methods related to Staphylococcal bacterium proteins
WO2007116322A2 (en) 2006-02-17 2007-10-18 Novartis Ag Purification of bacterial antigens
EP2476433A1 (en) 2006-03-30 2012-07-18 GlaxoSmithKline Biologicals S.A. Immunogenic composition
AR060187A1 (es) 2006-03-30 2008-05-28 Glaxosmithkline Biolog Sa Composicion inmunogenica
WO2014165164A2 (en) 2013-03-12 2014-10-09 Albany Medical College Compositions and methods for treating autoimmune diseases
GB201600075D0 (en) 2016-01-03 2016-02-17 Glaxosmithkline Biolog Sa Immunogenci composition
CN109562048A (zh) * 2016-02-05 2019-04-02 加州大学评议会 用于促进皮肤健康的组合物和方法
WO2017185018A1 (en) * 2016-04-21 2017-10-26 Naked Biome, Inc. Synthetic bacteria and methods of use
CN109689861A (zh) * 2016-05-15 2019-04-26 加州大学评议会 用于治疗痤疮的组合物和方法
US20210177920A1 (en) * 2017-12-05 2021-06-17 Biomx Ltd. Bacteriophage treatment for acne and biofilms
US12076352B2 (en) * 2018-06-19 2024-09-03 Glaxosmithkline Biologicals Sa Immunogenic composition
WO2020181180A1 (en) 2019-03-06 2020-09-10 The Broad Institute, Inc. A:t to c:g base editors and uses thereof
WO2020181178A1 (en) 2019-03-06 2020-09-10 The Broad Institute, Inc. T:a to a:t base editing through thymine alkylation
WO2020181195A1 (en) 2019-03-06 2020-09-10 The Broad Institute, Inc. T:a to a:t base editing through adenine excision
WO2020181202A1 (en) 2019-03-06 2020-09-10 The Broad Institute, Inc. A:t to t:a base editing through adenine deamination and oxidation
WO2020181193A1 (en) 2019-03-06 2020-09-10 The Broad Institute, Inc. T:a to a:t base editing through adenosine methylation
JP2023547677A (ja) 2020-11-04 2023-11-13 エリゴ・バイオサイエンス キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用

Similar Documents

Publication Publication Date Title
JP2023547676A5 (https=)
JP2023547677A5 (https=)
JP7232540B2 (ja) Crisprにより可能にされる多重ゲノムエンジニアリング
US11530405B2 (en) Anti-CRISPR genes and proteins and methods of use
CN103382468B (zh) 一种水稻基因组定点改造方法
JP2020511115A5 (https=)
CN103097537B (zh) 自删除质粒
KR20180015731A (ko) 캄필로박터 제주니 crispr/cas 시스템 유래 rgen을 이용한 유전체 교정
Karas et al. Strategies for cloning and manipulating natural and synthetic chromosomes
CN113950531A (zh) 使用m13噬菌体优化环状单链dna
JP2008533988A5 (https=)
KR20210046811A (ko) 락토바실러스 카제이 유래의 두 종류 프로모터를 이용한 두 가지 목적단백질의 동시 표면발현벡터 및 이를 이용한 단백질의 미생물표면 발현 방법
CN105567718B (zh) 一种同时表达多个sgRNA的载体的构建方法
EP2655620A1 (en) Dna expression construct
CN106987560A (zh) Rk‑13细胞hb基因敲除稳定株的构建方法
Yuan et al. A simple and efficient approach to construct mutant vaccinia virus vectors
JP2021522825A5 (https=)
CN114438106B (zh) Rv2779c基因及其表达产物作为抗结核分枝杆菌靶点的应用
JP2025503476A5 (https=)
CN112981544A (zh) 一种sgRNA文库构建方法
JP2023531718A5 (https=)
CN119751607B (zh) MgdE基因在调控牛分枝杆菌毒力中的应用
JP2022502081A (ja) 遺伝子操作された微生物ならびにそれを作製および使用する方法
Beznosov et al. Archaeal flagella as matrices for new nanomaterials
Yang TALEN and CRISPR/Cas9 for rice-genome editing