JP2021522825A5 - - Google Patents

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Publication number
JP2021522825A5
JP2021522825A5 JP2020563545A JP2020563545A JP2021522825A5 JP 2021522825 A5 JP2021522825 A5 JP 2021522825A5 JP 2020563545 A JP2020563545 A JP 2020563545A JP 2020563545 A JP2020563545 A JP 2020563545A JP 2021522825 A5 JP2021522825 A5 JP 2021522825A5
Authority
JP
Japan
Prior art keywords
domain
vector
isolated polypeptide
nucleic acid
sgrna
Prior art date
Application number
JP2020563545A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019213776A5 (https=
JP2021522825A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2019/050629 external-priority patent/WO2019213776A1/en
Publication of JP2021522825A publication Critical patent/JP2021522825A/ja
Publication of JP2021522825A5 publication Critical patent/JP2021522825A5/ja
Publication of JPWO2019213776A5 publication Critical patent/JPWO2019213776A5/ja
Pending legal-status Critical Current

Links

JP2020563545A 2018-05-11 2019-05-10 CRISPR/Cas9システムおよびその使用 Pending JP2021522825A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862670135P 2018-05-11 2018-05-11
US62/670,135 2018-05-11
PCT/CA2019/050629 WO2019213776A1 (en) 2018-05-11 2019-05-10 Crispr/cas9 system and uses thereof

Publications (3)

Publication Number Publication Date
JP2021522825A JP2021522825A (ja) 2021-09-02
JP2021522825A5 true JP2021522825A5 (https=) 2022-05-13
JPWO2019213776A5 JPWO2019213776A5 (https=) 2022-05-13

Family

ID=68467641

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020563545A Pending JP2021522825A (ja) 2018-05-11 2019-05-10 CRISPR/Cas9システムおよびその使用

Country Status (4)

Country Link
US (1) US12378549B2 (https=)
JP (1) JP2021522825A (https=)
CA (1) CA3101949A1 (https=)
WO (1) WO2019213776A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202313985A (zh) * 2021-05-16 2023-04-01 香港商正基基因科技有限公司 富集靶向核酸、鑑別脫靶及評估基因編輯效率之方法
GB202109675D0 (en) * 2021-07-05 2021-08-18 Ucl Business Ltd Treatment for tyrosine degradation-associated disorders
IL324634A (en) 2023-05-15 2026-01-01 Nchroma Bio Inc Compositions and methods for epigenetic regulation of hbv gene expression
WO2025194124A1 (en) * 2024-03-14 2025-09-18 Tessera Therapeutics, Inc. Modified st1cas9 guide nucleic acids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014093718A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Methods, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
JP6793547B2 (ja) * 2013-12-12 2020-12-02 ザ・ブロード・インスティテュート・インコーポレイテッド 最適化機能CRISPR−Cas系による配列操作のための系、方法および組成物
AU2014361834B2 (en) * 2013-12-12 2020-10-22 Massachusetts Institute Of Technology CRISPR-Cas systems and methods for altering expression of gene products, structural information and inducible modular Cas enzymes
US10900034B2 (en) * 2014-12-03 2021-01-26 Agilent Technologies, Inc. Guide RNA with chemical modifications
JP7109784B2 (ja) * 2015-10-23 2022-08-01 プレジデント アンド フェローズ オブ ハーバード カレッジ 遺伝子編集のための進化したCas9蛋白質

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