JP2024511163A5 - - Google Patents
Info
- Publication number
- JP2024511163A5 JP2024511163A5 JP2023558765A JP2023558765A JP2024511163A5 JP 2024511163 A5 JP2024511163 A5 JP 2024511163A5 JP 2023558765 A JP2023558765 A JP 2023558765A JP 2023558765 A JP2023558765 A JP 2023558765A JP 2024511163 A5 JP2024511163 A5 JP 2024511163A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- adenosine deaminase
- modifications
- group
- modification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163166778P | 2021-03-26 | 2021-03-26 | |
| US63/166,778 | 2021-03-26 | ||
| US202163229057P | 2021-08-03 | 2021-08-03 | |
| US63/229,057 | 2021-08-03 | ||
| PCT/US2022/022050 WO2022204574A1 (en) | 2021-03-26 | 2022-03-25 | Adenosine deaminase variants and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024511163A JP2024511163A (ja) | 2024-03-12 |
| JP2024511163A5 true JP2024511163A5 (https=) | 2025-04-01 |
Family
ID=83397962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023558765A Pending JP2024511163A (ja) | 2021-03-26 | 2022-03-25 | アデノシンデアミナーゼバリアント及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240158775A1 (https=) |
| EP (1) | EP4313118A4 (https=) |
| JP (1) | JP2024511163A (https=) |
| KR (1) | KR20240004276A (https=) |
| AU (1) | AU2022246176A1 (https=) |
| BR (1) | BR112023019539A2 (https=) |
| CA (1) | CA3214494A1 (https=) |
| WO (1) | WO2022204574A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020051562A2 (en) | 2018-09-07 | 2020-03-12 | Beam Therapeutics Inc. | Compositions and methods for improving base editing |
| EP3847254A4 (en) | 2018-09-07 | 2022-08-10 | Beam Therapeutics Inc. | COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM |
| AU2020215730A1 (en) | 2019-01-31 | 2021-07-29 | Beam Therapeutics Inc. | Nucleobase editors having reduced non-target deamination and assays for characterizing nucleobase editors |
| CN120174005A (zh) | 2019-02-13 | 2025-06-20 | 比姆医疗股份有限公司 | 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞 |
| EP4034138A4 (en) | 2019-09-27 | 2024-07-31 | Beam Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS |
| CA3196831A1 (en) | 2020-09-25 | 2022-03-31 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| EP4705444A2 (en) * | 2023-05-04 | 2026-03-11 | Technische Universität Dresden | Highly active crispr base editors obtained through cas-assisted substrate-linked directed evolution (caslide) |
| EP4458963A1 (en) * | 2023-05-04 | 2024-11-06 | Technische Universität Dresden | Highly active crispr base editors obtained through cas-assisted substrate-linked directed evolution (caslide) |
| CN120290534A (zh) * | 2024-01-10 | 2025-07-11 | 上海数因信科智能科技有限公司 | 腺嘌呤脱氨酶、包含其的碱基编辑器融合蛋白和碱基编辑器系统及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017007765B1 (pt) * | 2014-10-14 | 2023-10-03 | Halozyme, Inc | Composições de adenosina deaminase-2 (ada2), variantes do mesmo e métodos de usar o mesmo |
| AU2020215730A1 (en) * | 2019-01-31 | 2021-07-29 | Beam Therapeutics Inc. | Nucleobase editors having reduced non-target deamination and assays for characterizing nucleobase editors |
| WO2020160517A1 (en) * | 2019-01-31 | 2020-08-06 | Beam Therapeutics Inc. | Nucleobase editors having reduced off-target deamination and methods of using same to modify a nucleobase target sequence |
| WO2021022043A2 (en) * | 2019-07-30 | 2021-02-04 | Pairwise Plants Services, Inc. | Morphogenic regulators and methods of using the same |
| WO2021042062A2 (en) * | 2019-08-30 | 2021-03-04 | Joung J Keith | Combinatorial adenine and cytosine dna base editors |
| AU2020344547A1 (en) * | 2019-09-09 | 2022-03-24 | Beam Therapeutics Inc. | Novel nucleobase editors and methods of using same |
-
2022
- 2022-03-25 EP EP22776767.0A patent/EP4313118A4/en active Pending
- 2022-03-25 JP JP2023558765A patent/JP2024511163A/ja active Pending
- 2022-03-25 KR KR1020237033780A patent/KR20240004276A/ko active Pending
- 2022-03-25 BR BR112023019539A patent/BR112023019539A2/pt unknown
- 2022-03-25 CA CA3214494A patent/CA3214494A1/en active Pending
- 2022-03-25 AU AU2022246176A patent/AU2022246176A1/en active Pending
- 2022-03-25 WO PCT/US2022/022050 patent/WO2022204574A1/en not_active Ceased
-
2023
- 2023-09-26 US US18/474,969 patent/US20240158775A1/en active Pending