JP2022545950A5 - - Google Patents
Info
- Publication number
- JP2022545950A5 JP2022545950A5 JP2022513443A JP2022513443A JP2022545950A5 JP 2022545950 A5 JP2022545950 A5 JP 2022545950A5 JP 2022513443 A JP2022513443 A JP 2022513443A JP 2022513443 A JP2022513443 A JP 2022513443A JP 2022545950 A5 JP2022545950 A5 JP 2022545950A5
- Authority
- JP
- Japan
- Prior art keywords
- tada
- spcas9
- variant
- deaminase
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025135451A JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962893638P | 2019-08-29 | 2019-08-29 | |
| US62/893,638 | 2019-08-29 | ||
| PCT/US2020/048510 WO2021041885A2 (en) | 2019-08-29 | 2020-08-28 | Compositions and methods for editing a mutation to permit transcription or expression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025135451A Division JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022545950A JP2022545950A (ja) | 2022-11-01 |
| JP2022545950A5 true JP2022545950A5 (https=) | 2023-09-05 |
| JP7781742B2 JP7781742B2 (ja) | 2025-12-08 |
Family
ID=74684607
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513443A Active JP7781742B2 (ja) | 2019-08-29 | 2020-08-28 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
| JP2025135451A Pending JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025135451A Pending JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220313799A1 (https=) |
| EP (1) | EP4022050A4 (https=) |
| JP (2) | JP7781742B2 (https=) |
| KR (1) | KR20220066289A (https=) |
| CN (2) | CN119913134A (https=) |
| AU (1) | AU2020336953A1 (https=) |
| CA (1) | CA3152861A1 (https=) |
| WO (1) | WO2021041885A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3847254A4 (en) | 2018-09-07 | 2022-08-10 | Beam Therapeutics Inc. | COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM |
| WO2020252455A1 (en) | 2019-06-13 | 2020-12-17 | The General Hospital Corporation | Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells |
| EP4143315A1 (en) | 2020-04-28 | 2023-03-08 | The Broad Institute Inc. | <smallcaps/>? ? ?ush2a? ? ? ? ?targeted base editing of thegene |
| CA3189601A1 (en) | 2020-07-24 | 2022-01-27 | The General Hospital Corporation | Enhanced virus-like particles and methods of use thereof for delivery to cells |
| US20240173353A1 (en) * | 2021-03-16 | 2024-05-30 | Shanghai Iaso Biotechnology Co., Ltd. | Universal chimeric antigen receptor t-cell and application thereof |
| KR20240007651A (ko) * | 2021-04-16 | 2024-01-16 | 빔 테라퓨틱스, 인크. | 간세포의 유전적 변형 |
| EP4441074A2 (en) | 2021-12-03 | 2024-10-09 | The Broad Institute, Inc. | Compositions and methods for efficient in vivo delivery |
| CN120303407A (zh) | 2022-05-17 | 2025-07-11 | 恩维洛普治疗有限责任公司 | 用于有效体内递送的组合物和方法 |
| KR20230166378A (ko) | 2022-05-30 | 2023-12-07 | 현대자동차주식회사 | 차량의 제동 방법 및 장치 |
| WO2024138131A1 (en) * | 2022-12-22 | 2024-06-27 | Trustees Of Tufts College | Expanding applications of zgtc alphabet in protein expression and gene editing |
| WO2025064656A1 (en) * | 2023-09-19 | 2025-03-27 | Beam Therapeutics Inc. | Compositions and methods for altering a nucleobase in a lipoprotein(a) polynucleotide |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003258437A1 (en) * | 2002-08-30 | 2004-03-19 | The Hospital For Sick Children | Diagnosis of shwachman-diamond syndrome |
| WO2009061442A1 (en) * | 2007-11-06 | 2009-05-14 | Children's Medical Center Corporation | Method to produce induced pluripotent stem (ips) cells form non-embryonic human cells |
| CN106604994B (zh) * | 2014-06-23 | 2021-12-14 | 通用医疗公司 | 通过测序评估的DSBs的全基因组无偏鉴定(GUIDE-Seq) |
| IL310721B2 (en) * | 2015-10-23 | 2025-11-01 | Harvard College | Nucleobase editors and uses thereof |
| WO2018119359A1 (en) * | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| AU2018251801B2 (en) * | 2017-04-12 | 2024-11-07 | Massachusetts Institute Of Technology | Novel type VI CRISPR orthologs and systems |
| KR20250107288A (ko) * | 2017-10-16 | 2025-07-11 | 더 브로드 인스티튜트, 인코퍼레이티드 | 아데노신 염기 편집제의 용도 |
| CN109306361B (zh) * | 2018-02-11 | 2022-06-28 | 华东师范大学 | 一种新的a/t到g/c碱基定点转换的基因编辑系统 |
-
2020
- 2020-08-28 JP JP2022513443A patent/JP7781742B2/ja active Active
- 2020-08-28 KR KR1020227010126A patent/KR20220066289A/ko active Pending
- 2020-08-28 CA CA3152861A patent/CA3152861A1/en active Pending
- 2020-08-28 AU AU2020336953A patent/AU2020336953A1/en active Pending
- 2020-08-28 CN CN202411970155.8A patent/CN119913134A/zh active Pending
- 2020-08-28 EP EP20856306.4A patent/EP4022050A4/en active Pending
- 2020-08-28 WO PCT/US2020/048510 patent/WO2021041885A2/en not_active Ceased
- 2020-08-28 CN CN202080076243.7A patent/CN114641567B/zh active Active
- 2020-08-28 US US17/638,757 patent/US20220313799A1/en active Pending
-
2025
- 2025-08-15 JP JP2025135451A patent/JP2025183226A/ja active Pending
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