JP2022532139A5 - - Google Patents

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Publication number
JP2022532139A5
JP2022532139A5 JP2021566276A JP2021566276A JP2022532139A5 JP 2022532139 A5 JP2022532139 A5 JP 2022532139A5 JP 2021566276 A JP2021566276 A JP 2021566276A JP 2021566276 A JP2021566276 A JP 2021566276A JP 2022532139 A5 JP2022532139 A5 JP 2022532139A5
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JP
Japan
Prior art keywords
hbv
tada
gene
nucleic acid
protein
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Application number
JP2021566276A
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English (en)
Japanese (ja)
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JP7679309B2 (ja
JP2022532139A (ja
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Priority claimed from PCT/US2020/032226 external-priority patent/WO2020231863A1/en
Publication of JP2022532139A publication Critical patent/JP2022532139A/ja
Publication of JP2022532139A5 publication Critical patent/JP2022532139A5/ja
Priority to JP2025033734A priority Critical patent/JP2025102768A/ja
Application granted granted Critical
Publication of JP7679309B2 publication Critical patent/JP7679309B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021566276A 2019-05-10 2020-05-08 B型肝炎を治療するための組成物及び方法 Active JP7679309B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025033734A JP2025102768A (ja) 2019-05-10 2025-03-04 B型肝炎を治療するための組成物及び方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962846422P 2019-05-10 2019-05-10
US62/846,422 2019-05-10
US201962927585P 2019-10-29 2019-10-29
US62/927,585 2019-10-29
PCT/US2020/032226 WO2020231863A1 (en) 2019-05-10 2020-05-08 Compositions and methods for treating hepatitis b

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025033734A Division JP2025102768A (ja) 2019-05-10 2025-03-04 B型肝炎を治療するための組成物及び方法

Publications (3)

Publication Number Publication Date
JP2022532139A JP2022532139A (ja) 2022-07-13
JP2022532139A5 true JP2022532139A5 (https=) 2023-05-16
JP7679309B2 JP7679309B2 (ja) 2025-05-19

Family

ID=73289231

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021566276A Active JP7679309B2 (ja) 2019-05-10 2020-05-08 B型肝炎を治療するための組成物及び方法
JP2025033734A Pending JP2025102768A (ja) 2019-05-10 2025-03-04 B型肝炎を治療するための組成物及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025033734A Pending JP2025102768A (ja) 2019-05-10 2025-03-04 B型肝炎を治療するための組成物及び方法

Country Status (8)

Country Link
US (1) US20230070861A1 (https=)
EP (1) EP3965832A4 (https=)
JP (2) JP7679309B2 (https=)
KR (1) KR20220019685A (https=)
CN (2) CN120586100A (https=)
AU (1) AU2020276218A1 (https=)
CA (1) CA3139324A1 (https=)
WO (1) WO2020231863A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3847254A4 (en) 2018-09-07 2022-08-10 Beam Therapeutics Inc. COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM
EP4143315A1 (en) 2020-04-28 2023-03-08 The Broad Institute Inc. <smallcaps/>? ? ?ush2a? ? ? ? ?targeted base editing of thegene
US12171813B2 (en) 2021-02-05 2024-12-24 Christiana Care Gene Editing Institute, Inc. Methods of and compositions for reducing gene expression and/or activity
WO2022192634A1 (en) * 2021-03-12 2022-09-15 Massachusetts Institute Of Technology Compositions and methods for dominant antiviral therapy
EP4373518A2 (en) * 2021-07-22 2024-05-29 Emendobio Inc. Hepatitis b virus (hbv) knockouts
CN119013394A (zh) * 2021-09-27 2024-11-22 比姆医疗股份有限公司 用于治疗乙型肝炎病毒感染的组合物和方法
WO2024103049A1 (en) * 2022-11-11 2024-05-16 The United States Government As Represented By The Department Of Veterans Affairs Cd33 specific exosomes and uses thereof
TW202436622A (zh) * 2023-03-06 2024-09-16 美商英特利亞醫療公司 用於b型肝炎病毒(hbv)基因體編輯之組合物及方法
AU2024270764A1 (en) 2023-05-15 2025-12-04 Nchroma Bio, Inc. Compositions and methods for epigenetic regulation of hbv gene expression

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2716420C2 (ru) * 2013-06-17 2020-03-11 Те Брод Инститьют Инк. Доставка и применение систем crispr-cas, векторов и композиций для целенаправленного воздействия и терапии в печени
SG10201804975PA (en) 2013-12-12 2018-07-30 Broad Inst Inc Delivery, Use and Therapeutic Applications of the Crispr-Cas Systems and Compositions for HBV and Viral Diseases and Disorders
CA3001351A1 (en) * 2015-10-21 2017-04-27 Editas Medicine, Inc. Crispr/cas-related methods and compositions for treating hepatitis b virus
CN110214183A (zh) * 2016-08-03 2019-09-06 哈佛大学的校长及成员们 腺苷核碱基编辑器及其用途
EP3565608A4 (en) * 2017-01-05 2020-12-16 Rutgers, The State University of New Jersey TARGETED GENE EDITING PLATFORM INDEPENDENT OF BICATENARY DNA BREAKAGE AND ITS USES
WO2019005886A1 (en) * 2017-06-26 2019-01-03 The Broad Institute, Inc. CRISPR / CAS-CYTIDINE DEAMINASE COMPOSITIONS, SYSTEMS AND METHODS FOR TARGETED EDITING OF NUCLEIC ACIDS
CN111801345A (zh) * 2017-07-28 2020-10-20 哈佛大学的校长及成员们 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物

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