JP2025102768A5 - - Google Patents
Info
- Publication number
- JP2025102768A5 JP2025102768A5 JP2025033734A JP2025033734A JP2025102768A5 JP 2025102768 A5 JP2025102768 A5 JP 2025102768A5 JP 2025033734 A JP2025033734 A JP 2025033734A JP 2025033734 A JP2025033734 A JP 2025033734A JP 2025102768 A5 JP2025102768 A5 JP 2025102768A5
- Authority
- JP
- Japan
- Prior art keywords
- hbv
- gene
- cas9
- domain
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962846422P | 2019-05-10 | 2019-05-10 | |
| US62/846,422 | 2019-05-10 | ||
| US201962927585P | 2019-10-29 | 2019-10-29 | |
| US62/927,585 | 2019-10-29 | ||
| PCT/US2020/032226 WO2020231863A1 (en) | 2019-05-10 | 2020-05-08 | Compositions and methods for treating hepatitis b |
| JP2021566276A JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021566276A Division JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025102768A JP2025102768A (ja) | 2025-07-08 |
| JP2025102768A5 true JP2025102768A5 (https=) | 2025-08-13 |
Family
ID=73289231
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021566276A Active JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
| JP2025033734A Pending JP2025102768A (ja) | 2019-05-10 | 2025-03-04 | Ｂ型肝炎を治療するための組成物及び方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021566276A Active JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230070861A1 (https=) |
| EP (1) | EP3965832A4 (https=) |
| JP (2) | JP7679309B2 (https=) |
| KR (1) | KR20220019685A (https=) |
| CN (2) | CN120586100A (https=) |
| AU (1) | AU2020276218A1 (https=) |
| CA (1) | CA3139324A1 (https=) |
| WO (1) | WO2020231863A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3847254A4 (en) | 2018-09-07 | 2022-08-10 | Beam Therapeutics Inc. | COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM |
| EP4143315A1 (en) | 2020-04-28 | 2023-03-08 | The Broad Institute Inc. | <smallcaps/>? ? ?ush2a? ? ? ? ?targeted base editing of thegene |
| US12171813B2 (en) | 2021-02-05 | 2024-12-24 | Christiana Care Gene Editing Institute, Inc. | Methods of and compositions for reducing gene expression and/or activity |
| WO2022192634A1 (en) * | 2021-03-12 | 2022-09-15 | Massachusetts Institute Of Technology | Compositions and methods for dominant antiviral therapy |
| EP4373518A2 (en) * | 2021-07-22 | 2024-05-29 | Emendobio Inc. | Hepatitis b virus (hbv) knockouts |
| CN119013394A (zh) * | 2021-09-27 | 2024-11-22 | 比姆医疗股份有限公司 | 用于治疗乙型肝炎病毒感染的组合物和方法 |
| WO2024103049A1 (en) * | 2022-11-11 | 2024-05-16 | The United States Government As Represented By The Department Of Veterans Affairs | Cd33 specific exosomes and uses thereof |
| TW202436622A (zh) * | 2023-03-06 | 2024-09-16 | 美商英特利亞醫療公司 | 用於ｂ型肝炎病毒（ｈｂｖ）基因體編輯之組合物及方法 |
| AU2024270764A1 (en) | 2023-05-15 | 2025-12-04 | Nchroma Bio, Inc. | Compositions and methods for epigenetic regulation of hbv gene expression |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2716420C2 (ru) * | 2013-06-17 | 2020-03-11 | Те Брод Инститьют Инк. | Доставка и применение систем crispr-cas, векторов и композиций для целенаправленного воздействия и терапии в печени |
| SG10201804975PA (en) | 2013-12-12 | 2018-07-30 | Broad Inst Inc | Delivery, Use and Therapeutic Applications of the Crispr-Cas Systems and Compositions for HBV and Viral Diseases and Disorders |
| CA3001351A1 (en) * | 2015-10-21 | 2017-04-27 | Editas Medicine, Inc. | Crispr/cas-related methods and compositions for treating hepatitis b virus |
| CN110214183A (zh) * | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| EP3565608A4 (en) * | 2017-01-05 | 2020-12-16 | Rutgers, The State University of New Jersey | TARGETED GENE EDITING PLATFORM INDEPENDENT OF BICATENARY DNA BREAKAGE AND ITS USES |
| WO2019005886A1 (en) * | 2017-06-26 | 2019-01-03 | The Broad Institute, Inc. | CRISPR / CAS-CYTIDINE DEAMINASE COMPOSITIONS, SYSTEMS AND METHODS FOR TARGETED EDITING OF NUCLEIC ACIDS |
| CN111801345A (zh) * | 2017-07-28 | 2020-10-20 | 哈佛大学的校长及成员们 | 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物 |
-
2020
- 2020-05-08 CA CA3139324A patent/CA3139324A1/en active Pending
- 2020-05-08 CN CN202510594053.9A patent/CN120586100A/zh active Pending
- 2020-05-08 CN CN202080050214.3A patent/CN114929287B/zh active Active
- 2020-05-08 AU AU2020276218A patent/AU2020276218A1/en active Pending
- 2020-05-08 US US17/610,119 patent/US20230070861A1/en active Pending
- 2020-05-08 WO PCT/US2020/032226 patent/WO2020231863A1/en not_active Ceased
- 2020-05-08 JP JP2021566276A patent/JP7679309B2/ja active Active
- 2020-05-08 KR KR1020217039921A patent/KR20220019685A/ko active Pending
- 2020-05-08 EP EP20806106.9A patent/EP3965832A4/en active Pending
-
2025
- 2025-03-04 JP JP2025033734A patent/JP2025102768A/ja active Pending
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