JP2022533673A5 - - Google Patents
Info
- Publication number
- JP2022533673A5 JP2022533673A5 JP2021568855A JP2021568855A JP2022533673A5 JP 2022533673 A5 JP2022533673 A5 JP 2022533673A5 JP 2021568855 A JP2021568855 A JP 2021568855A JP 2021568855 A JP2021568855 A JP 2021568855A JP 2022533673 A5 JP2022533673 A5 JP 2022533673A5
- Authority
- JP
- Japan
- Prior art keywords
- tada
- rett
- mecp2
- adenosine deaminase
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962850919P | 2019-05-21 | 2019-05-21 | |
| US62/850,919 | 2019-05-21 | ||
| PCT/US2020/033807 WO2020236936A1 (en) | 2019-05-21 | 2020-05-20 | Methods of editing a single nucleotide polymorphism using programmable base editor systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022533673A JP2022533673A (ja) | 2022-07-25 |
| JP2022533673A5 true JP2022533673A5 (https=) | 2023-05-29 |
| JP7679311B2 JP7679311B2 (ja) | 2025-05-19 |
Family
ID=73459015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021568855A Active JP7679311B2 (ja) | 2019-05-21 | 2020-05-20 | プログラム可能塩基エディターシステムを用いた一塩基多型編集法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220387622A1 (https=) |
| EP (1) | EP3972654A4 (https=) |
| JP (1) | JP7679311B2 (https=) |
| KR (1) | KR20220010540A (https=) |
| CN (2) | CN120346348A (https=) |
| AU (1) | AU2020279751A1 (https=) |
| CA (1) | CA3140093A1 (https=) |
| WO (1) | WO2020236936A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019178427A1 (en) | 2018-03-14 | 2019-09-19 | Arbor Biotechnologies, Inc. | Novel crispr dna targeting enzymes and systems |
| AU2019265019B2 (en) | 2018-05-11 | 2025-11-06 | Beam Therapeutics Inc. | Methods of substituting pathogenic amino acids using programmable base editor systems |
| WO2019222555A1 (en) | 2018-05-16 | 2019-11-21 | Arbor Biotechnologies, Inc. | Novel crispr-associated systems and components |
| EP3847254A4 (en) | 2018-09-07 | 2022-08-10 | Beam Therapeutics Inc. | COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM |
| WO2020051562A2 (en) | 2018-09-07 | 2020-03-12 | Beam Therapeutics Inc. | Compositions and methods for improving base editing |
| JP7693552B2 (ja) * | 2019-02-13 | 2025-06-17 | ビーム セラピューティクス インク． | アデノシンデアミナーゼ塩基エディターおよびそれを用いて標的配列中の核酸塩基を改変する方法 |
| CN120174005A (zh) | 2019-02-13 | 2025-06-20 | 比姆医疗股份有限公司 | 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞 |
| EP4034138A4 (en) | 2019-09-27 | 2024-07-31 | Beam Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS |
| CA3196831A1 (en) | 2020-09-25 | 2022-03-31 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| US20240352439A1 (en) * | 2021-09-03 | 2024-10-24 | The University Of Chicago | Polypeptides and methods for modifying nucleic acids |
| EP4404942A2 (en) * | 2021-09-26 | 2024-07-31 | Wave Life Sciences Ltd. | Compositions for editing mecp2 transcripts and methods thereof |
| US20250154479A1 (en) * | 2022-01-24 | 2025-05-15 | Toolgen Incorporated | Streptococcus pyogenes-derived cas9 variant |
| JP2025530183A (ja) * | 2022-09-08 | 2025-09-11 | ザ ユニヴァーシティ コート オブ ザ ユニヴァーシティ オブ エディンバラ | レット症候群治療法 |
| EP4615574A2 (en) * | 2022-11-08 | 2025-09-17 | The Board Of Trustees Of The Leland Stanford Junior University | Muscle-specific base editors for correction of mutations causing dilated cardiomyopathy |
| CN117965505A (zh) * | 2023-06-28 | 2024-05-03 | 微光基因(苏州)有限公司 | 工程化的腺苷脱氨酶及碱基编辑器 |
| WO2025014806A1 (en) * | 2023-07-07 | 2025-01-16 | Myriad Genetics, Inc. | Multiple-ancestry polygenic risk assessment for breast cancer |
| WO2025199339A2 (en) * | 2024-03-20 | 2025-09-25 | Shape Therapeutics Inc. | Mecp2-targeting engineered guide rnas and polynucleotides |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX374532B (es) * | 2013-06-17 | 2025-03-06 | Broad Inst Inc | Suministro, uso y aplicaciones terapéuticas de los sistemas y composiciones crispr-cas, para actuar sobre trastornos y enfermedades utilizando componentes víricos. |
| CN105683379A (zh) * | 2013-06-17 | 2016-06-15 | 布罗德研究所有限公司 | 用于对有丝分裂后细胞的疾病和障碍进行靶向和建模的系统、方法和组合物的递送、工程化和优化 |
| JP7044373B2 (ja) * | 2015-07-15 | 2022-03-30 | ラトガース，ザ ステート ユニバーシティ オブ ニュージャージー | ヌクレアーゼ非依存的な標的化遺伝子編集プラットフォームおよびその用途 |
| CN110214183A (zh) * | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| BR112019019833A2 (pt) * | 2017-03-24 | 2020-04-22 | The University Court Of The University Of Edinburgh | terapia baseada em mecp2 |
| WO2019071274A1 (en) * | 2017-10-06 | 2019-04-11 | Oregon Health & Science University | Compositions and methods for editing rna |
| KR20250107288A (ko) * | 2017-10-16 | 2025-07-11 | 더 브로드 인스티튜트, 인코퍼레이티드 | 아데노신 염기 편집제의 용도 |
| EP3699267A4 (en) | 2017-10-17 | 2021-10-27 | Kyoto University | PROCESS FOR OBTAINING AN ARTIFICIAL NEUROMUSCULAR JUNCTION FROM PLURIPOTENT STEM CELLS |
| KR20250133482A (ko) * | 2018-05-11 | 2025-09-05 | 빔 테라퓨틱스, 인크. | 프로그래밍가능한 염기 편집기 시스템을 이용하여 단일 뉴클레오티드 다형성을 편집하는 방법 |
-
2020
- 2020-05-20 AU AU2020279751A patent/AU2020279751A1/en active Pending
- 2020-05-20 US US17/612,879 patent/US20220387622A1/en active Pending
- 2020-05-20 CA CA3140093A patent/CA3140093A1/en active Pending
- 2020-05-20 KR KR1020217041287A patent/KR20220010540A/ko active Pending
- 2020-05-20 CN CN202510277023.5A patent/CN120346348A/zh active Pending
- 2020-05-20 EP EP20809005.0A patent/EP3972654A4/en active Pending
- 2020-05-20 CN CN202080052684.3A patent/CN114206395B/zh active Active
- 2020-05-20 WO PCT/US2020/033807 patent/WO2020236936A1/en not_active Ceased
- 2020-05-20 JP JP2021568855A patent/JP7679311B2/ja active Active
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