JP2024541811A5 - - Google Patents
Info
- Publication number
- JP2024541811A5 JP2024541811A5 JP2024519975A JP2024519975A JP2024541811A5 JP 2024541811 A5 JP2024541811 A5 JP 2024541811A5 JP 2024519975 A JP2024519975 A JP 2024519975A JP 2024519975 A JP2024519975 A JP 2024519975A JP 2024541811 A5 JP2024541811 A5 JP 2024541811A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- nucleic acid
- manipulated
- editing system
- cytidine deaminase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163276461P | 2021-11-05 | 2021-11-05 | |
| US63/276,461 | 2021-11-05 | ||
| US202163289998P | 2021-12-15 | 2021-12-15 | |
| US63/289,998 | 2021-12-15 | ||
| US202263342824P | 2022-05-17 | 2022-05-17 | |
| US63/342,824 | 2022-05-17 | ||
| US202263356888P | 2022-06-29 | 2022-06-29 | |
| US63/356,888 | 2022-06-29 | ||
| US202263378171P | 2022-10-03 | 2022-10-03 | |
| US63/378,171 | 2022-10-03 | ||
| PCT/US2022/079345 WO2023081855A1 (en) | 2021-11-05 | 2022-11-04 | Base editing enzymes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024541811A JP2024541811A (ja) | 2024-11-13 |
| JP2024541811A5 true JP2024541811A5 (https=) | 2025-11-05 |
Family
ID=86242250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024519975A Pending JP2024541811A (ja) | 2021-11-05 | 2022-11-04 | 塩基編集酵素 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12503710B2 (https=) |
| EP (1) | EP4426826A4 (https=) |
| JP (1) | JP2024541811A (https=) |
| KR (1) | KR20240099283A (https=) |
| AU (1) | AU2022380842A1 (https=) |
| CA (1) | CA3234217A1 (https=) |
| MX (1) | MX2024005505A (https=) |
| WO (1) | WO2023081855A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023540797A (ja) * | 2020-09-11 | 2023-09-26 | メタゲノミ，インコーポレイテッド | 塩基編集酵素 |
| CA3205865A1 (en) * | 2021-01-22 | 2022-07-28 | Brian C. Thomas | Novel engineered and chimeric nucleases |
| WO2023081855A1 (en) | 2021-11-05 | 2023-05-11 | Metagenomi, Inc. | Base editing enzymes |
| AU2023235279A1 (en) * | 2022-03-14 | 2024-10-03 | Metagenomi Therapeutics, Inc. | Engineered and chimeric nucleases |
| CN119351373A (zh) * | 2023-07-24 | 2025-01-24 | 北京志道生物科技有限公司 | 一种核酸内切酶及其应用 |
| WO2025081064A2 (en) * | 2023-10-11 | 2025-04-17 | Illumina, Inc. | Thermophilic deaminase and methods for identifying modified cytosine |
| WO2025119295A1 (zh) * | 2023-12-05 | 2025-06-12 | 广州瑞风生物科技有限公司 | 脱氨酶、融合蛋白、核酸、药物组合物及其应用 |
| WO2025207709A1 (en) * | 2024-03-26 | 2025-10-02 | Arbor Biotechnologies, Inc. | Reverse transcription-mediated gene editing systems and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11192929B2 (en) | 2016-12-08 | 2021-12-07 | Regents Of The University Of Minnesota | Site-specific DNA base editing using modified APOBEC enzymes |
| EP3572525A4 (en) | 2017-01-17 | 2020-09-30 | Institute for Basic Science | PROCEDURE FOR IDENTIFYING AN OFF-TARGET BASIC EDITING SITE BY BREAKING A SINGLE DNA STRAND |
| KR20240116572A (ko) * | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| EP3617311B1 (en) | 2017-03-30 | 2024-11-20 | Kyoto University | Method for inducing exon skipping by genome editing |
| US9982279B1 (en) | 2017-06-23 | 2018-05-29 | Inscripta, Inc. | Nucleic acid-guided nucleases |
| KR102761791B1 (ko) | 2017-06-26 | 2025-02-05 | 더 브로드 인스티튜트, 인코퍼레이티드 | 표적화된 핵산 편집을 위한 crispr/cas-아데닌 데아미나아제 기반 조성물, 시스템 및 방법 |
| JP2021506251A (ja) | 2017-12-14 | 2021-02-22 | クリスパー セラピューティクス アーゲー | 新規ｒｎａプログラム可能エンドヌクレアーゼ系、ならびにゲノム編集および他の適用におけるその使用 |
| US11946040B2 (en) | 2019-02-04 | 2024-04-02 | The General Hospital Corporation | Adenine DNA base editor variants with reduced off-target RNA editing |
| US20220298494A1 (en) | 2019-02-14 | 2022-09-22 | Metagenomi Ip Technologies, Llc | Enzymes with ruvc domains |
| CA3241703C (en) | 2019-02-14 | 2026-02-24 | Metagenomi Therapeutics, Inc. | Enzymes with ruvc domains |
| WO2021097118A1 (en) | 2019-11-12 | 2021-05-20 | The Broad Institute, Inc. | Small type ii cas proteins and methods of use thereof |
| WO2021202568A1 (en) | 2020-03-31 | 2021-10-07 | Metagenomi Ip Technologies, Llc | Class ii, type ii crispr systems |
| JP2023540797A (ja) * | 2020-09-11 | 2023-09-26 | メタゲノミ，インコーポレイテッド | 塩基編集酵素 |
| GB2700205B (en) | 2020-09-11 | 2026-04-15 | Metagenomi Therapeutics Inc | Base editing enzymes |
| WO2023081855A1 (en) | 2021-11-05 | 2023-05-11 | Metagenomi, Inc. | Base editing enzymes |
-
2022
- 2022-11-04 WO PCT/US2022/079345 patent/WO2023081855A1/en not_active Ceased
- 2022-11-04 AU AU2022380842A patent/AU2022380842A1/en active Pending
- 2022-11-04 JP JP2024519975A patent/JP2024541811A/ja active Pending
- 2022-11-04 MX MX2024005505A patent/MX2024005505A/es unknown
- 2022-11-04 KR KR1020247015992A patent/KR20240099283A/ko active Pending
- 2022-11-04 EP EP22891120.2A patent/EP4426826A4/en active Pending
- 2022-11-04 CA CA3234217A patent/CA3234217A1/en active Pending
-
2024
- 2024-05-02 US US18/653,454 patent/US12503710B2/en active Active
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