JP2024541811A5 - - Google Patents

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Publication number
JP2024541811A5
JP2024541811A5 JP2024519975A JP2024519975A JP2024541811A5 JP 2024541811 A5 JP2024541811 A5 JP 2024541811A5 JP 2024519975 A JP2024519975 A JP 2024519975A JP 2024519975 A JP2024519975 A JP 2024519975A JP 2024541811 A5 JP2024541811 A5 JP 2024541811A5
Authority
JP
Japan
Application number
JP2024519975A
Other languages
Japanese (ja)
Other versions
JPWO2023081855A5 (https=
JP2024541811A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/079345 external-priority patent/WO2023081855A1/en
Publication of JP2024541811A publication Critical patent/JP2024541811A/ja
Publication of JP2024541811A5 publication Critical patent/JP2024541811A5/ja
Publication of JPWO2023081855A5 publication Critical patent/JPWO2023081855A5/ja
Pending legal-status Critical Current

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JP2024519975A 2021-11-05 2022-11-04 塩基編集酵素 Pending JP2024541811A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202163276461P 2021-11-05 2021-11-05
US63/276,461 2021-11-05
US202163289998P 2021-12-15 2021-12-15
US63/289,998 2021-12-15
US202263342824P 2022-05-17 2022-05-17
US63/342,824 2022-05-17
US202263356888P 2022-06-29 2022-06-29
US63/356,888 2022-06-29
US202263378171P 2022-10-03 2022-10-03
US63/378,171 2022-10-03
PCT/US2022/079345 WO2023081855A1 (en) 2021-11-05 2022-11-04 Base editing enzymes

Publications (3)

Publication Number Publication Date
JP2024541811A JP2024541811A (ja) 2024-11-13
JP2024541811A5 true JP2024541811A5 (https=) 2025-11-05
JPWO2023081855A5 JPWO2023081855A5 (https=) 2025-11-05

Family

ID=86242250

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024519975A Pending JP2024541811A (ja) 2021-11-05 2022-11-04 塩基編集酵素

Country Status (8)

Country Link
US (1) US12503710B2 (https=)
EP (1) EP4426826A4 (https=)
JP (1) JP2024541811A (https=)
KR (1) KR20240099283A (https=)
AU (1) AU2022380842A1 (https=)
CA (1) CA3234217A1 (https=)
MX (1) MX2024005505A (https=)
WO (1) WO2023081855A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3192224A1 (en) 2020-09-11 2022-03-17 Jyun-Liang LIN Base editing enzymes
BR112023014719A2 (pt) * 2021-01-22 2023-12-05 Metagenomi Inc Novas nucleases quiméricas e manipuladas
AU2022380842A1 (en) 2021-11-05 2024-05-23 Metagenomi Therapeutics, Inc. Base editing enzymes
WO2023178115A2 (en) * 2022-03-14 2023-09-21 Metagenomi, Inc. Engineered and chimeric nucleases
CN119351373A (zh) * 2023-07-24 2025-01-24 北京志道生物科技有限公司 一种核酸内切酶及其应用
WO2025081064A2 (en) * 2023-10-11 2025-04-17 Illumina, Inc. Thermophilic deaminase and methods for identifying modified cytosine
WO2025119295A1 (zh) * 2023-12-05 2025-06-12 广州瑞风生物科技有限公司 脱氨酶、融合蛋白、核酸、药物组合物及其应用
WO2025207709A1 (en) * 2024-03-26 2025-10-02 Arbor Biotechnologies, Inc. Reverse transcription-mediated gene editing systems and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11192929B2 (en) 2016-12-08 2021-12-07 Regents Of The University Of Minnesota Site-specific DNA base editing using modified APOBEC enzymes
EP3572525A4 (en) 2017-01-17 2020-09-30 Institute for Basic Science PROCEDURE FOR IDENTIFYING AN OFF-TARGET BASIC EDITING SITE BY BREAKING A SINGLE DNA STRAND
CA3057192A1 (en) * 2017-03-23 2018-09-27 President And Fellows Of Harvard College Nucleobase editors comprising nucleic acid programmable dna binding proteins
KR102758434B1 (ko) 2017-03-30 2025-01-21 고쿠리츠 다이가쿠 호진 교토 다이가쿠 게놈 편집에 의한 엑손 스키핑 유도 방법
US9982279B1 (en) 2017-06-23 2018-05-29 Inscripta, Inc. Nucleic acid-guided nucleases
AU2018290843B2 (en) 2017-06-26 2025-04-24 Massachusetts Institute Of Technology CRISPR/Cas-adenine deaminase based compositions, systems, and methods for targeted nucleic acid editing
JP2021506251A (ja) 2017-12-14 2021-02-22 クリスパー セラピューティクス アーゲー 新規rnaプログラム可能エンドヌクレアーゼ系、ならびにゲノム編集および他の適用におけるその使用
US11946040B2 (en) 2019-02-04 2024-04-02 The General Hospital Corporation Adenine DNA base editor variants with reduced off-target RNA editing
US20220298494A1 (en) 2019-02-14 2022-09-22 Metagenomi Ip Technologies, Llc Enzymes with ruvc domains
AU2020223370B2 (en) 2019-02-14 2023-04-20 Metagenomi Therapeutics, Inc. Enzymes with RuvC domains
WO2021097118A1 (en) 2019-11-12 2021-05-20 The Broad Institute, Inc. Small type ii cas proteins and methods of use thereof
GB2608292B (en) 2020-03-31 2024-02-14 Metagenomi Inc Class II, type II CRISPR systems
GB2700205B (en) 2020-09-11 2026-04-15 Metagenomi Therapeutics Inc Base editing enzymes
CA3192224A1 (en) 2020-09-11 2022-03-17 Jyun-Liang LIN Base editing enzymes
AU2022380842A1 (en) 2021-11-05 2024-05-23 Metagenomi Therapeutics, Inc. Base editing enzymes

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