JP2022520428A5 - - Google Patents

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Publication number
JP2022520428A5
JP2022520428A5 JP2021547336A JP2021547336A JP2022520428A5 JP 2022520428 A5 JP2022520428 A5 JP 2022520428A5 JP 2021547336 A JP2021547336 A JP 2021547336A JP 2021547336 A JP2021547336 A JP 2021547336A JP 2022520428 A5 JP2022520428 A5 JP 2022520428A5
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JP
Japan
Application number
JP2021547336A
Other languages
Japanese (ja)
Other versions
JPWO2020168291A5 (https=
JP2022520428A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/018432 external-priority patent/WO2020168291A1/en
Publication of JP2022520428A publication Critical patent/JP2022520428A/ja
Publication of JPWO2020168291A5 publication Critical patent/JPWO2020168291A5/ja
Publication of JP2022520428A5 publication Critical patent/JP2022520428A5/ja
Priority to JP2023146414A priority Critical patent/JP7502537B2/ja
Priority to JP2024091759A priority patent/JP2024133476A/ja
Ceased legal-status Critical Current

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JP2021547336A 2019-02-14 2020-02-14 Ruvcドメインを有する酵素 Ceased JP2022520428A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023146414A JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素
JP2024091759A JP2024133476A (ja) 2019-02-14 2024-06-05 Ruvcドメインを有する酵素

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962805868P 2019-02-14 2019-02-14
US201962805878P 2019-02-14 2019-02-14
US201962805899P 2019-02-14 2019-02-14
US62/805,878 2019-02-14
US62/805,868 2019-02-14
US62/805,899 2019-02-14
US201962874414P 2019-07-15 2019-07-15
US62/874,414 2019-07-15
PCT/US2020/018432 WO2020168291A1 (en) 2019-02-14 2020-02-14 Enzymes with ruvc domains

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023146414A Division JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素

Publications (3)

Publication Number Publication Date
JP2022520428A JP2022520428A (ja) 2022-03-30
JPWO2020168291A5 JPWO2020168291A5 (https=) 2023-02-21
JP2022520428A5 true JP2022520428A5 (https=) 2023-02-21

Family

ID=72045639

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2021547336A Ceased JP2022520428A (ja) 2019-02-14 2020-02-14 Ruvcドメインを有する酵素
JP2023146414A Active JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素
JP2024091759A Pending JP2024133476A (ja) 2019-02-14 2024-06-05 Ruvcドメインを有する酵素

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023146414A Active JP7502537B2 (ja) 2019-02-14 2023-09-08 Ruvcドメインを有する酵素
JP2024091759A Pending JP2024133476A (ja) 2019-02-14 2024-06-05 Ruvcドメインを有する酵素

Country Status (9)

Country Link
US (1) US20240117330A1 (https=)
EP (1) EP3924482A4 (https=)
JP (3) JP2022520428A (https=)
KR (2) KR102623312B1 (https=)
CN (2) CN113728098A (https=)
AU (3) AU2020223370B2 (https=)
CA (2) CA3130135C (https=)
MX (2) MX2021009886A (https=)
WO (1) WO2020168291A1 (https=)

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EP3204496A1 (en) 2014-10-10 2017-08-16 Editas Medicine, Inc. Compositions and methods for promoting homology directed repair
EP3823633A4 (en) 2018-06-29 2023-05-03 Editas Medicine, Inc. SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO
US10913941B2 (en) 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
AU2020223370B2 (en) * 2019-02-14 2023-04-20 Metagenomi Therapeutics, Inc. Enzymes with RuvC domains
GB2594339B (en) * 2020-02-14 2023-02-08 Metagenomi Inc Enzymes with RUVC domains
GB2617658B (en) 2020-03-06 2024-04-17 Metagenomi Inc Class II, type V CRISPR systems
GB2608292B (en) * 2020-03-31 2024-02-14 Metagenomi Inc Class II, type II CRISPR systems
EP4165177A4 (en) * 2020-05-08 2024-08-28 Metagenomi, Inc. ENZYMES WITH RUVC DOMAINS
KR20230021657A (ko) * 2020-05-08 2023-02-14 메타지노미, 인크. Ruvc 도메인을 포함하는 효소
CA3192224A1 (en) 2020-09-11 2022-03-17 Jyun-Liang LIN Base editing enzymes
GB2700205B (en) * 2020-09-11 2026-04-15 Metagenomi Therapeutics Inc Base editing enzymes
US20230383273A1 (en) * 2020-10-21 2023-11-30 Emendobio Inc. Novel omni 56, 58, 65, 68, 71, 75, 78, and 84 crispr nucleases
WO2022098681A2 (en) * 2020-11-03 2022-05-12 Caspr Biotech Corporation Novel class 2 crispr-cas rna-guided endonucleases
WO2022159742A1 (en) * 2021-01-22 2022-07-28 Metagenomi, Inc Novel engineered and chimeric nucleases
BR112023014719A2 (pt) * 2021-01-22 2023-12-05 Metagenomi Inc Novas nucleases quiméricas e manipuladas
BR112023018948A2 (pt) * 2021-03-19 2023-10-17 Metagenomi Inc Edição multiplex com enzimas cas
WO2022232638A2 (en) * 2021-04-30 2022-11-03 Metagenomi, Inc. Enzymes with ruvc domains
CA3225082A1 (en) * 2021-08-27 2023-03-02 Brian C. Thomas Enzymes with ruvc domains
AU2022380842A1 (en) 2021-11-05 2024-05-23 Metagenomi Therapeutics, Inc. Base editing enzymes
MX2024006257A (es) 2021-11-24 2024-07-29 Metagenomi Inc Sistemas de endonucleasas.
WO2023122663A2 (en) * 2021-12-23 2023-06-29 Mammoth Biosciences, Inc. Effector proteins and methods of use
WO2023194359A1 (en) * 2022-04-04 2023-10-12 Alia Therapeutics Srl Compositions and methods for treatment of usher syndrome type 2a
CN119923466A (zh) * 2022-06-15 2025-05-02 比姆医疗股份有限公司 用于减少补体激活的组合物和方法
US20260014279A1 (en) * 2022-09-16 2026-01-15 Alia Therapeutics Srl Enqp type cas proteins and applications thereof
KR20250153814A (ko) * 2023-03-01 2025-10-27 메타지노미, 인크. Ruvc 도메인을 갖는 효소
WO2025106934A1 (en) * 2023-11-16 2025-05-22 Metagenomi, Inc. Enzymes with ruvc domains

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2894684A1 (en) * 2012-12-12 2014-06-19 The Broad Institute, Inc. Engineering and optimization of improved crispr-cas systems, methods and enzyme compositions for sequence manipulation in eukaryotes
EP3303634B1 (en) * 2015-06-03 2023-08-30 The Regents of The University of California Cas9 variants and methods of use thereof
WO2016205759A1 (en) * 2015-06-18 2016-12-22 The Broad Institute Inc. Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
US12431216B2 (en) * 2016-08-17 2025-09-30 Broad Institute, Inc. Methods for identifying class 2 crispr-cas systems
KR20200124702A (ko) * 2018-02-23 2020-11-03 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 신규한 cas9 오르소로그
AU2020223370B2 (en) 2019-02-14 2023-04-20 Metagenomi Therapeutics, Inc. Enzymes with RuvC domains

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