JP2023540081A5 - - Google Patents
Info
- Publication number
- JP2023540081A5 JP2023540081A5 JP2023513934A JP2023513934A JP2023540081A5 JP 2023540081 A5 JP2023540081 A5 JP 2023540081A5 JP 2023513934 A JP2023513934 A JP 2023513934A JP 2023513934 A JP2023513934 A JP 2023513934A JP 2023540081 A5 JP2023540081 A5 JP 2023540081A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- compound
- ring
- nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063074446P | 2020-09-03 | 2020-09-03 | |
| US63/074,446 | 2020-09-03 | ||
| US202063124713P | 2020-12-11 | 2020-12-11 | |
| US63/124,713 | 2020-12-11 | ||
| US202163196146P | 2021-06-02 | 2021-06-02 | |
| US63/196,146 | 2021-06-02 | ||
| PCT/US2021/049084 WO2022051634A1 (en) | 2020-09-03 | 2021-09-03 | Quinoline cgas antagonist compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023540081A JP2023540081A (ja) | 2023-09-21 |
| JP2023540081A5 true JP2023540081A5 (https=) | 2024-09-10 |
Family
ID=78086041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023513934A Pending JP2023540081A (ja) | 2020-09-03 | 2021-09-03 | キノリンｃｇａｓアンタゴニスト化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US11873291B2 (https=) |
| EP (1) | EP4208452A1 (https=) |
| JP (1) | JP2023540081A (https=) |
| KR (1) | KR20230062845A (https=) |
| CN (1) | CN116234802A (https=) |
| AU (1) | AU2021336977A1 (https=) |
| BR (1) | BR112023003948A2 (https=) |
| CA (1) | CA3191172A1 (https=) |
| IL (1) | IL300976A (https=) |
| MX (1) | MX2023002553A (https=) |
| TW (1) | TW202227407A (https=) |
| WO (1) | WO2022051634A1 (https=) |
| ZA (1) | ZA202304064B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021209473A1 (en) * | 2020-04-16 | 2021-10-21 | F. Hoffmann-La Roche Ag | Biphenyl derivatives |
| KR20230062845A (ko) | 2020-09-03 | 2023-05-09 | 이뮨센서 테라퓨틱스, 인코포레이티드 | 퀴놀린 cgas 길항제 화합물 |
| WO2022137085A1 (en) | 2020-12-22 | 2022-06-30 | Novartis Ag | Indole derivatives useful in treating conditions associated with cgas |
| IL315346A (en) | 2022-03-02 | 2024-11-01 | Immunesensor Therapeutics Inc | CGAS agonistic quinoline compounds |
| CN118265696A (zh) * | 2022-11-07 | 2024-06-28 | 深圳博瑞医药科技有限公司 | 一种芳基羧酸类化合物及其制备Mrgpr X4抑制剂的用途 |
| WO2024099135A1 (zh) * | 2022-11-11 | 2024-05-16 | 杭州中美华东制药有限公司 | 1,5-萘啶类cGAS抑制剂及其用途 |
| AU2024326748A1 (en) | 2023-08-18 | 2026-04-02 | Katholieke Universiteit Leuven | 1,3-dihydro-2h-pyrrolo[3,4-c]quinoline derivatives as cgas inhibitors for the treatment of inflammatory and/or autoimmune diseases |
| GB202314609D0 (en) * | 2023-09-22 | 2023-11-08 | Univ College Cardiff Consultants Ltd | Iminosugar prodrug compounds |
| WO2025147600A1 (en) * | 2024-01-05 | 2025-07-10 | Dewpoint Therapeutics, Inc. | Amino quinoline compounds and uses thereof |
| WO2026057087A1 (zh) * | 2024-09-14 | 2026-03-19 | 杭州英创医药科技有限公司 | 作为cGAS抑制剂的化合物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3542785A (en) | 1967-05-15 | 1970-11-24 | Ciba Geigy Corp | 2-hydroxy-4-aryl-quinolines |
| US3668207A (en) | 1970-01-22 | 1972-06-06 | Ciba Geigy Corp | 2-amino-4-aryl-quinolines |
| BR0312204A (pt) | 2002-06-27 | 2005-04-26 | Schering Ag | Antagonista de receptor ccr5 de quinolina substituìda |
| WO2009005677A2 (en) * | 2007-06-29 | 2009-01-08 | Gilead Sciences, Inc. | Antiviral compounds |
| CA2699697A1 (en) | 2007-09-27 | 2009-04-02 | F. Hoffmann-La Roche Ag | Quinoline derivatives as 5ht5a receptor antagonists |
| US20190127354A1 (en) | 2015-12-14 | 2019-05-02 | Fundación Para La Investigación Médica Aplicada | 2,4,6,7-tetrasubstituted quinoline compounds as inhibitors of dna methyltransferases |
| CN109111426B (zh) * | 2017-06-23 | 2021-12-14 | 中国科学院上海药物研究所 | 一类稠合双环杂芳基或芳基化合物，及其用途 |
| KR20240151869A (ko) * | 2017-09-08 | 2024-10-18 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | Enpp1 저해제 및 암의 치료용의 이의 용도 |
| WO2019241787A1 (en) | 2018-06-15 | 2019-12-19 | The Regents Of The University Of Colorado A Body Corporate | Novel cyclic gmp-amp synthase (cgas) inhibitors and their method of use |
| PL3829581T3 (pl) * | 2018-07-27 | 2024-07-01 | Arcus Biosciences, Inc. | Antagoniści pirydonu a2r |
| EP3620164A1 (en) | 2018-09-05 | 2020-03-11 | Genoscience Pharma SAS | Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases |
| CA3125626A1 (en) | 2019-01-04 | 2020-07-09 | Bellbrook Labs, Llc | Inhibitors of cgas activity as therapeutic agents |
| US11245538B2 (en) * | 2019-09-28 | 2022-02-08 | Intel Corporation | Methods and apparatus to aggregate telemetry data in an edge environment |
| AU2021211437A1 (en) | 2020-01-20 | 2022-09-15 | Crescenta Biosciences | Novel cell metabolism modulating compounds and uses thereof |
| WO2022010948A1 (en) | 2020-07-06 | 2022-01-13 | Crescenta Biosciences | Novel cell metabolism modulating compounds and uses thereof for the treatment of viral diseases |
| KR20230062845A (ko) | 2020-09-03 | 2023-05-09 | 이뮨센서 테라퓨틱스, 인코포레이티드 | 퀴놀린 cgas 길항제 화합물 |
| IL315346A (en) | 2022-03-02 | 2024-11-01 | Immunesensor Therapeutics Inc | CGAS agonistic quinoline compounds |
-
2021
- 2021-09-03 KR KR1020237010887A patent/KR20230062845A/ko active Pending
- 2021-09-03 WO PCT/US2021/049084 patent/WO2022051634A1/en not_active Ceased
- 2021-09-03 JP JP2023513934A patent/JP2023540081A/ja active Pending
- 2021-09-03 AU AU2021336977A patent/AU2021336977A1/en active Pending
- 2021-09-03 BR BR112023003948A patent/BR112023003948A2/pt unknown
- 2021-09-03 EP EP21789905.3A patent/EP4208452A1/en active Pending
- 2021-09-03 IL IL300976A patent/IL300976A/en unknown
- 2021-09-03 TW TW110132911A patent/TW202227407A/zh unknown
- 2021-09-03 CA CA3191172A patent/CA3191172A1/en active Pending
- 2021-09-03 MX MX2023002553A patent/MX2023002553A/es unknown
- 2021-09-03 US US17/446,951 patent/US11873291B2/en active Active
- 2021-09-03 CN CN202180073688.4A patent/CN116234802A/zh active Pending
-
2023
- 2023-03-31 ZA ZA2023/04064A patent/ZA202304064B/en unknown
- 2023-06-13 US US18/334,325 patent/US12134609B2/en active Active
-
2024
- 2024-09-10 US US18/829,953 patent/US20250115579A1/en active Pending
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