JP2021519776A5 - - Google Patents
Info
- Publication number
- JP2021519776A5 JP2021519776A5 JP2020552805A JP2020552805A JP2021519776A5 JP 2021519776 A5 JP2021519776 A5 JP 2021519776A5 JP 2020552805 A JP2020552805 A JP 2020552805A JP 2020552805 A JP2020552805 A JP 2020552805A JP 2021519776 A5 JP2021519776 A5 JP 2021519776A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- alkyl
- haloalkyl
- alkoxy
- optionally substituted
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023144744A JP2023171752A (ja) | 2018-03-27 | 2023-09-06 | Ｏｘ２ｒ化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862648933P | 2018-03-27 | 2018-03-27 | |
| US62/648,933 | 2018-03-27 | ||
| PCT/US2019/024426 WO2019191327A1 (en) | 2018-03-27 | 2019-03-27 | Ox2r compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023144744A Division JP2023171752A (ja) | 2018-03-27 | 2023-09-06 | Ｏｘ２ｒ化合物 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021519776A JP2021519776A (ja) | 2021-08-12 |
| JPWO2019191327A5 JPWO2019191327A5 (https=) | 2022-04-01 |
| JP2021519776A5 true JP2021519776A5 (https=) | 2022-04-01 |
| JP7346439B2 JP7346439B2 (ja) | 2023-09-19 |
Family
ID=68060742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020552805A Active JP7346439B2 (ja) | 2018-03-27 | 2019-03-27 | Ｏｘ２ｒ化合物 |
| JP2023144744A Pending JP2023171752A (ja) | 2018-03-27 | 2023-09-06 | Ｏｘ２ｒ化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023144744A Pending JP2023171752A (ja) | 2018-03-27 | 2023-09-06 | Ｏｘ２ｒ化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US11472813B2 (https=) |
| EP (1) | EP3773566A4 (https=) |
| JP (2) | JP7346439B2 (https=) |
| KR (1) | KR20210010443A (https=) |
| CN (1) | CN112165940A (https=) |
| AU (1) | AU2019243141A1 (https=) |
| BR (1) | BR112020019818A2 (https=) |
| CA (1) | CA3095451C (https=) |
| CO (1) | CO2020013492A2 (https=) |
| IL (1) | IL277651A (https=) |
| MX (1) | MX2020010155A (https=) |
| SG (1) | SG11202009615UA (https=) |
| WO (1) | WO2019191327A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112165940A (zh) * | 2018-03-27 | 2021-01-01 | 德克萨斯州立大学董事会 | Ox2r化合物 |
| WO2021061801A1 (en) * | 2019-09-24 | 2021-04-01 | Icahn School Of Medicine At Mt. Sinai | Bicyclic inhibitors of cbx chromodomains |
| EP4065585B1 (en) | 2019-11-25 | 2025-08-20 | Alkermes, Inc. | Substituted macrocyclic compounds and related methods of treatment |
| US12006330B2 (en) | 2020-12-21 | 2024-06-11 | Alkermes, Inc. | Substituted macrocyclic compounds and related methods of treatment |
| US11760747B2 (en) | 2020-12-21 | 2023-09-19 | Alkermes, Inc. | Substituted piperidino compounds and related methods of treatment |
| US20240174605A1 (en) * | 2021-03-03 | 2024-05-30 | Research Triangle Institute | Arylsulfonamides as orexin receptor agonists |
| KR20240026483A (ko) * | 2021-06-25 | 2024-02-28 | 재즈 파마슈티칼즈 아일랜드 리미티드 | 술폰아미드 오렉신 수용체 효능제 및 그의 용도 |
| WO2025124698A1 (en) | 2023-12-12 | 2025-06-19 | Idorsia Pharmaceuticals Ltd | Aryl sulfone and sulfanone derivatives as orexin receptor modulators |
| TW202542165A (zh) | 2023-12-19 | 2025-11-01 | 瑞士商愛杜西亞製藥有限公司 | 大環食慾素激動劑 |
| WO2025224168A1 (en) | 2024-04-24 | 2025-10-30 | Idorsia Pharmaceuticals Ltd | Aryl sulfone and sulfanone derivatives as orexin receptor modulators |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4004016A (en) * | 1975-08-11 | 1977-01-18 | E. R. Squibb & Sons, Inc. | Amino-benzimidazole derivatives |
| US6521623B1 (en) * | 2000-09-19 | 2003-02-18 | Boehringer Ingelheim Pharma Kg | N,N'-disubstituted benzimidazolone derivatives with affinity at the serotonin and dopamine receptors |
| US7842817B2 (en) * | 2005-01-11 | 2010-11-30 | Neurosearch A/S | 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels |
| US8871794B2 (en) * | 2008-06-04 | 2014-10-28 | Board Of Regents, The University Of Texas System | Small-molecule agonists for type-2 orexin receptor |
| US8258163B2 (en) * | 2008-06-04 | 2012-09-04 | Board Of Regents, The University Of Texas System | Small-molecule agonists for type-2 orexin receptor |
| US8633233B2 (en) * | 2008-08-06 | 2014-01-21 | Hydra Biosciences, Inc. | Methods and compositions for treating anxiety |
| EP2364313B1 (en) * | 2008-09-09 | 2014-01-08 | Boehringer Ingelheim International GmbH | Aza-benzimidazolone chymase inhibitors |
| WO2013068592A1 (en) * | 2011-11-10 | 2013-05-16 | Fondation Jerome Lejeune | Inhibitors of cystathionine beta synthase to reduce the neurotoxic overproduction of endogenous hydrogen sulfide |
| MX2014014657A (es) * | 2012-06-01 | 2015-08-10 | Nogra Pharma Ltd | Heterociclos bicíclicos capaces de modular las respuestas de los linfocitos t, y métodos de uso de los mismos. |
| CN112165940A (zh) * | 2018-03-27 | 2021-01-01 | 德克萨斯州立大学董事会 | Ox2r化合物 |
-
2019
- 2019-03-27 CN CN201980035485.9A patent/CN112165940A/zh active Pending
- 2019-03-27 JP JP2020552805A patent/JP7346439B2/ja active Active
- 2019-03-27 AU AU2019243141A patent/AU2019243141A1/en not_active Abandoned
- 2019-03-27 BR BR112020019818-8A patent/BR112020019818A2/pt not_active Application Discontinuation
- 2019-03-27 WO PCT/US2019/024426 patent/WO2019191327A1/en not_active Ceased
- 2019-03-27 CA CA3095451A patent/CA3095451C/en active Active
- 2019-03-27 KR KR1020207030352A patent/KR20210010443A/ko not_active Ceased
- 2019-03-27 MX MX2020010155A patent/MX2020010155A/es unknown
- 2019-03-27 SG SG11202009615UA patent/SG11202009615UA/en unknown
- 2019-03-27 EP EP19774927.8A patent/EP3773566A4/en not_active Withdrawn
-
2020
- 2020-09-27 US US17/033,879 patent/US11472813B2/en active Active
- 2020-09-29 IL IL277651A patent/IL277651A/en unknown
- 2020-10-27 CO CONC2020/0013492A patent/CO2020013492A2/es unknown
- 2020-11-20 US US17/100,810 patent/US11479560B2/en active Active
-
2022
- 2022-10-21 US US17/971,547 patent/US11905297B2/en active Active
-
2023
- 2023-09-06 JP JP2023144744A patent/JP2023171752A/ja active Pending
-
2024
- 2024-02-08 US US18/436,024 patent/US20240174685A1/en not_active Abandoned
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