JP2002536329A5 - - Google Patents

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Publication number
JP2002536329A5
JP2002536329A5 JP2000596934A JP2000596934A JP2002536329A5 JP 2002536329 A5 JP2002536329 A5 JP 2002536329A5 JP 2000596934 A JP2000596934 A JP 2000596934A JP 2000596934 A JP2000596934 A JP 2000596934A JP 2002536329 A5 JP2002536329 A5 JP 2002536329A5
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JP
Japan
Prior art keywords
methylene
phenylenebis
bis
linker
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000596934A
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English (en)
Japanese (ja)
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JP2002536329A (ja
JP4968868B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/CA2000/000104 external-priority patent/WO2000045814A1/en
Publication of JP2002536329A publication Critical patent/JP2002536329A/ja
Publication of JP2002536329A5 publication Critical patent/JP2002536329A5/ja
Application granted granted Critical
Publication of JP4968868B2 publication Critical patent/JP4968868B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000596934A 1999-02-02 2000-02-02 白血球数を高めるための方法および組成物 Expired - Fee Related JP4968868B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11825599P 1999-02-02 1999-02-02
US60/118,255 1999-02-02
PCT/CA2000/000104 WO2000045814A1 (en) 1999-02-02 2000-02-02 Methods and compositions to enhance white blood cell count

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011023235A Division JP2011088937A (ja) 1999-02-02 2011-02-04 白血球数を高めるための方法および組成物

Publications (3)

Publication Number Publication Date
JP2002536329A JP2002536329A (ja) 2002-10-29
JP2002536329A5 true JP2002536329A5 (https=) 2007-03-15
JP4968868B2 JP4968868B2 (ja) 2012-07-04

Family

ID=22377471

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000596934A Expired - Fee Related JP4968868B2 (ja) 1999-02-02 2000-02-02 白血球数を高めるための方法および組成物
JP2011023235A Withdrawn JP2011088937A (ja) 1999-02-02 2011-02-04 白血球数を高めるための方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011023235A Withdrawn JP2011088937A (ja) 1999-02-02 2011-02-04 白血球数を高めるための方法および組成物

Country Status (24)

Country Link
US (2) US6365583B1 (https=)
EP (1) EP1148875B1 (https=)
JP (2) JP4968868B2 (https=)
KR (1) KR100643553B1 (https=)
CN (1) CN1310642C (https=)
AP (1) AP1497A (https=)
AT (1) ATE268597T1 (https=)
AU (2) AU772979B2 (https=)
BR (1) BR0007924A (https=)
CA (1) CA2361587C (https=)
CZ (1) CZ20012698A3 (https=)
DE (1) DE60011391T2 (https=)
DK (1) DK1148875T3 (https=)
ES (1) ES2222174T3 (https=)
HK (1) HK1038319B (https=)
HU (1) HUP0200100A3 (https=)
IL (1) IL144400A (https=)
MX (1) MXPA01007801A (https=)
NO (1) NO20013770L (https=)
NZ (1) NZ513602A (https=)
PT (1) PT1148875E (https=)
SI (1) SI1148875T1 (https=)
TR (1) TR200102239T2 (https=)
WO (1) WO2000045814A1 (https=)

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AU2334301A (en) * 1999-12-17 2001-06-25 Anormed Inc. Chemokine receptor binding heterocyclic compounds
US8435939B2 (en) 2000-09-05 2013-05-07 Biokine Therapeutics Ltd. Polypeptide anti-HIV agent containing the same
US6734191B2 (en) * 2000-09-15 2004-05-11 Anormed, Inc. Chemokine receptor binding heterocyclic compounds
DE60137435D1 (de) * 2000-09-15 2009-03-05 Anormed Inc Chemokin rezeptor bindenden heterozyklische verbindungen
DE60136476D1 (de) 2000-09-29 2008-12-18 Anormed Inc -stickstoffhaltigen zyklischen polyaminen und deren verbindungen
US7169750B2 (en) * 2001-07-31 2007-01-30 Anormed, Inc. Methods to mobilize progenitor/stem cells
DK1411918T3 (da) * 2001-07-31 2012-04-23 Genzyme Global S A R L Fremgangsmåder til at mobilisere progenitor/stamceller
JP4431389B2 (ja) * 2001-09-12 2010-03-10 アノーメッド インコーポレイティド 鏡像異性的に純粋なアミノ置換縮合二環式環の合成
US7354932B2 (en) * 2001-12-21 2008-04-08 Anormed, Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
PL369856A1 (en) * 2001-12-21 2005-05-02 Anormed Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
AU2003261723A1 (en) 2002-08-27 2004-03-19 Takeda Chemical Industries, Ltd. Cxcr4 antagonist and use thereof
WO2004091518A2 (en) 2003-04-11 2004-10-28 Anormed Inc. Cxcr4 chemokine receptor binding compounds
JP4778420B2 (ja) 2003-04-22 2011-09-21 アノーメッド インコーポレイティド 増強された有効性を有するケモカインレセプタ結合複素環式化合物
US7501518B2 (en) * 2003-04-22 2009-03-10 Genzyme Corporation Methods of making 2,6-diaryl piperidine derivatives
US7498346B2 (en) * 2003-12-11 2009-03-03 Genzyme Corporation Chemokine receptor binding compounds
EP1708703A4 (en) * 2003-12-11 2008-04-09 Anormed Inc CHEMOKIN RECEPTOR BINDING COMPOUNDS
JP2008509928A (ja) * 2004-08-13 2008-04-03 アノーメド インコーポレイテッド 前駆/幹細胞を動員するためのケモカインの組み合わせ
WO2006138350A2 (en) * 2005-06-15 2006-12-28 Anormed Inc. Chemokine receptor binding compounds
CA2619881A1 (en) * 2005-08-16 2007-02-22 Genzyme Corporation Chemokine receptor binding compounds
CA2643209A1 (en) * 2006-02-24 2007-09-20 Genzyme Corporation Methods for increasing blood flow and/or promoting tissue regeneration
US20100003224A1 (en) * 2006-08-02 2010-01-07 Genzyme Corporation Combination Therapy
CN101500595A (zh) * 2006-08-07 2009-08-05 健赞股份有限公司 组合治疗
WO2008075371A2 (en) * 2006-12-21 2008-06-26 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for immunomodulation
US9155780B2 (en) 2009-02-11 2015-10-13 Yeda Research And Development Co. Ltd. Short beta-defensin-derived peptides
BRPI1009663A2 (pt) 2009-06-14 2016-10-11 Biokine Therapeutics Ltd "método para elevação dos níveis plaquetários em um indivíduo com essa necessidade, método de inibição de hemorragia em um indivíduo que a necessite e composição farmacêutica"
WO2012019168A2 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
KR20140045411A (ko) * 2011-05-16 2014-04-16 젠자임 코포레이션 Cxcr4 길항제의 용도
EP2841084B1 (en) 2012-04-24 2018-05-30 Biokine Therapeutics Ltd. Cxcr4 antagonist peptide for use in the treatment of large cell lung cancer
US10786547B2 (en) 2015-07-16 2020-09-29 Biokine Therapeutics Ltd. Compositions, articles of manufacture and methods for treating cancer
CA3008279A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109069426B (zh) 2015-12-14 2021-10-29 X4 制药有限公司 治疗癌症的方法
WO2017112894A1 (en) 2015-12-22 2017-06-29 X4 Pharmaceuticals, Inc. Methods for treating immunodeficiency disease
KR102033920B1 (ko) 2016-02-23 2019-10-18 바이오라인알엑스 리미티드 급성 골수성 백혈병을 치료하는 방법
CA3019394A1 (en) 2016-04-08 2017-10-12 X4 Pharmaceuticals, Inc. Methods for treating cancer
EP3472129A4 (en) 2016-06-21 2019-12-04 X4 Pharmaceuticals, Inc. CXCR4 INHIBITORS AND USES THEREOF
CN109640988A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
ES2870920T3 (es) 2016-06-21 2021-10-28 X4 Pharmaceuticals Inc Inhibidores de CXCR4 y usos de los mismos
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
CN109187337A (zh) * 2018-09-10 2019-01-11 南京工业职业技术学院 一种筛选强韧性FeAl晶界的方法
CA3171250A1 (en) 2020-03-10 2021-09-16 E. Lynne KELLEY Methods for treating neutropenia

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US4810643A (en) 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
US5021409A (en) 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
GB9126677D0 (en) 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
GB9400411D0 (en) 1994-01-11 1994-03-09 Johnson Matthey Plc Improvements in chemical compounds
US5612478A (en) 1995-03-30 1997-03-18 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
US5606053A (en) 1995-05-02 1997-02-25 Johnson Matthey Plc Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
US6506770B1 (en) 1996-06-06 2003-01-14 Anormed, Inc. Antiviral compounds
GB9511357D0 (en) 1995-06-06 1995-08-02 Johnson Matthey Plc Improved antiviral compounds
JP2002529502A (ja) * 1998-11-17 2002-09-10 スミスクライン・ビーチャム・コーポレイション 血小板減少症の治療法

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