|
AU4537900A
(en)
|
1999-05-17 |
2000-12-05 |
Agouron Pharmaceuticals, Inc. |
Glucagon antagonists/inverse agonists
|
|
EP1187810A2
(en)
|
1999-05-25 |
2002-03-20 |
Sepracor, Inc. |
Heterocyclic analgesic compounds and their use
|
|
US6511980B2
(en)
|
2000-05-05 |
2003-01-28 |
Ortho Mcneil Pharmaceutical, Inc. |
Substituted diamine derivatives useful as motilin antagonists
|
|
WO2001092226A1
(en)
|
2000-05-25 |
2001-12-06 |
Sepracor, Inc. |
Heterocyclic analgesic compounds and method of use thereof
|
|
HUP0303360A2
(hu)
|
2000-09-25 |
2004-01-28 |
Actelion Pharmaceuticals Ltd. |
Maláriaellenes hatású szubsztituált amino-aza-cikloalkánok és ezeket tartalmazó gyógyszerkészítmények
|
|
FR2815032B1
(fr)
|
2000-10-10 |
2003-08-08 |
Pf Medicament |
Nouveaux derives d'aminophenyle piperazine ou d'amino phenyle piperide inhibiteurs de proteines prenyl transferase ainsi que leurs preparations
|
|
FR2825706B1
(fr)
|
2001-06-06 |
2003-12-12 |
Pf Medicament |
Nouveaux derives de benzothienyle ou d'indole, leur preparation et leur utilisation comme inhibiteurs de proteines prenyl transferase
|
|
FR2839974B1
(fr)
|
2002-05-24 |
2004-07-16 |
Pf Medicament |
Derives de phenyl-furane ou de phenyl-thiophene,leur preparation et leur application a titre de medicament
|
|
WO2004009549A2
(en)
|
2002-07-18 |
2004-01-29 |
Actelion Pharmaceuticals Ltd |
Piperidines useful for the treatment of central nervous system disorders
|
|
MXPA05003054A
(es)
|
2002-09-20 |
2005-05-27 |
Pfizer Prod Inc |
Ligandos de amida y sulfonamida para el receptor de estrogenos.
|
|
AU2003290796A1
(en)
|
2002-11-14 |
2004-06-15 |
The Scripps Research Institute |
Non-steroidal fxr agonists
|
|
US20050143449A1
(en)
*
|
2002-11-15 |
2005-06-30 |
The Salk Institute For Biological Studies |
Non-steroidal farnesoid X receptor modulators and methods for the use thereof
|
|
WO2004046323A2
(en)
|
2002-11-15 |
2004-06-03 |
The Salk Institute For Biological Studies |
Structure of the farnesoid x receptor ligand binding domain and methods of use therefor
|
|
GB0309781D0
(en)
|
2003-04-29 |
2003-06-04 |
Glaxo Group Ltd |
Compounds
|
|
US7759348B2
(en)
|
2003-07-30 |
2010-07-20 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives and their use as therapeutic agents
|
|
US7754711B2
(en)
|
2003-07-30 |
2010-07-13 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives and their use as therapeutic agents
|
|
EP2316827B1
(en)
|
2003-07-30 |
2016-01-27 |
Xenon Pharmaceuticals Inc. |
Piperazine derivatives and their use as therapeutic agents
|
|
WO2005058822A1
(en)
|
2003-12-17 |
2005-06-30 |
Actelion Pharmaceuticals Ltd |
Substituted amino-cycloalkanes
|
|
CN1914205A
(zh)
|
2003-12-19 |
2007-02-14 |
葛兰素集团有限公司 |
吡唑并[3,4－b]吡啶化合物及其作为磷酸二酯酶抑制剂的用途
|
|
WO2005089316A2
(en)
|
2004-03-12 |
2005-09-29 |
Intercept Pharmaceuticals, Inc. |
Treatment of fibrosis using fxr ligands
|
|
JP2007530582A
(ja)
|
2004-03-26 |
2007-11-01 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
代謝可能部分を含む複素環抗ウイルス化合物およびその使用
|
|
US20050272784A1
(en)
|
2004-05-07 |
2005-12-08 |
Xiaobing Li |
Inhibitors of bacterial Type III protein secretion systems
|
|
JP2006199656A
(ja)
|
2005-01-24 |
2006-08-03 |
Kowa Co |
アミド基を有する環状アミン化合物
|
|
MY144229A
(en)
|
2006-01-26 |
2011-08-15 |
Xenon Pharmaceuticals Inc |
Pyridazine derivatives and their use as therapeutic agents
|
|
CN101395170A
(zh)
|
2006-02-14 |
2009-03-25 |
英特塞普特药品公司 |
用于预防或治疗fxr介导的疾病或状态的作为fxr配体的胆汁酸衍生物
|
|
CA2644369A1
(en)
|
2006-03-28 |
2007-10-04 |
Novartis Ag |
Amide derivatives and their application for the treatment of g protein related diseases
|
|
US20080081824A1
(en)
|
2006-09-29 |
2008-04-03 |
Bristol-Myers Squibb Company |
Substituted piperidines as modulators of chemokine receptor activity
|
|
WO2008065500A2
(en)
|
2006-11-30 |
2008-06-05 |
Pfizer Products Inc. |
Heteroaryl amides as type i glycine transport inhibitors
|
|
EP2234977A4
(en)
|
2007-12-19 |
2011-04-13 |
Boehringer Ingelheim Int |
VIRAL POLYMERASE INHIBITORS
|
|
US20090270418A1
(en)
|
2008-01-09 |
2009-10-29 |
Marianne Sloss |
Pyrazole pyrazine amine compounds as kinase inhibitors, compositions thereof and methods of treatment therewith
|
|
US20100029657A1
(en)
|
2008-02-29 |
2010-02-04 |
Wyeth |
Bridged, Bicyclic Heterocyclic or Spiro Bicyclic Heterocyclic Derivatives of Pyrazolo[1, 5-A]Pyrimidines, Methods for Preparation and Uses Thereof
|
|
WO2010001869A1
(ja)
|
2008-06-30 |
2010-01-07 |
武田薬品工業株式会社 |
４置換ベンゼン化合物およびその用途
|
|
JP2010077109A
(ja)
|
2008-08-28 |
2010-04-08 |
Takeda Chem Ind Ltd |
複素環化合物およびその用途
|
|
CA2749893A1
(en)
|
2009-02-04 |
2010-08-12 |
Pfizer Inc. |
4-amino-7,8-dihydropyrido[4,3-d]pyrimidin-5(6h)-one derivatives
|
|
AU2010272523A1
(en)
|
2009-07-15 |
2012-02-02 |
Merck Serono S.A. |
Tetrazole derivatives
|
|
US8435980B2
(en)
|
2009-07-15 |
2013-05-07 |
Abbvie Inc. |
Pyrrolopyridine inhibitors of kinases
|
|
FR2963005B1
(fr)
|
2010-07-23 |
2012-08-17 |
Sanofi Aventis |
Derives d'oxadiazoles et de pyridazines, leur preparation et leur application en therapeutique
|
|
JP2014500319A
(ja)
|
2010-12-20 |
2014-01-09 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
ファルネソイドｘ受容体を調節するための組成物および方法
|
|
RU2600739C2
(ru)
|
2011-03-18 |
2016-10-27 |
Байер Интеллектчуал Проперти Гмбх |
N-(3-карбамоилфенил)-1н-пиразол-5-карбоксамидные производные и их применение для борьбы с животными-вредителями
|
|
ME02754B
(me)
|
2011-03-23 |
2018-01-20 |
Trevena Inc |
Ligandi opioidnih receptora i postupci njihove upotrebe i pripreme
|
|
WO2013008706A1
(ja)
|
2011-07-13 |
2013-01-17 |
エム・テクニック株式会社 |
結晶子径を制御された微粒子の製造方法
|
|
EP2545964A1
(en)
|
2011-07-13 |
2013-01-16 |
Phenex Pharmaceuticals AG |
Novel FXR (NR1H4) binding and activity modulating compounds
|
|
WO2013037482A1
(en)
|
2011-09-15 |
2013-03-21 |
Phenex Pharmaceuticals Ag |
Farnesoid x receptor agonists for cancer treatment and prevention
|
|
RU2543485C2
(ru)
|
2013-02-26 |
2015-03-10 |
Андрей Александрович Иващенко |
Гетероциклические агонисты рецепторов желчных кислот tgr5, фармацевтическая композиция, способы их получения и применения
|
|
MX377523B
(es)
|
2013-09-11 |
2025-03-10 |
Inst Nat Sante Rech Med |
Metodos y composiciones farmaceuticas para el tratamiento de la infeccion por el virus de la hepatitis b.
|
|
GB201316824D0
(en)
|
2013-09-23 |
2013-11-06 |
R & D Vernalis Ltd |
New Chemical Entities
|
|
JP2017511304A
(ja)
|
2014-03-13 |
2017-04-20 |
ソーク インスティチュート フォー バイオロジカル スタディーズ |
フェキサラミン類似体ならびに作製方法および使用方法
|
|
US20150258052A1
(en)
|
2014-03-13 |
2015-09-17 |
Salk Institute For Biological Studies |
Methods of using fexaramine and agents that increase sympathetic nervous system activity to promote browning of white adipose tissue
|
|
CA2942403A1
(en)
|
2014-03-13 |
2015-09-17 |
Salk Institute For Biological Studies |
Fxr agonists and methods for making and using
|
|
US10301268B2
(en)
|
2014-03-13 |
2019-05-28 |
The Salk Institute For Biological Studies |
Analogs of fexaramine and methods of making and using
|
|
US10077268B2
(en)
|
2014-03-13 |
2018-09-18 |
Salk Institute For Biological Studies |
FXR agonists and methods for making and using
|
|
US20180116993A1
(en)
|
2015-01-22 |
2018-05-03 |
Xiamen University |
Modulators of farnesoid x receptor and methods for the use thereof
|
|
AU2016233579A1
(en)
|
2015-03-13 |
2017-10-12 |
Salk Institute For Biological Studies |
Treating latent autoimmune diabetes of adults with farnesoid X receptor agonists to activate intestinal receptors
|
|
WO2017018751A1
(ko)
|
2015-07-24 |
2017-02-02 |
동국대학교 산학협력단 |
Blt 저해 활성을 갖는 신규 화합물 및 이를 유효성분으로 포함하는 염증성 질환 예방 또는 치료용 조성물
|
|
WO2017049176A1
(en)
|
2015-09-16 |
2017-03-23 |
Metacrine, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
EP3350165B1
(en)
|
2015-09-16 |
2023-07-26 |
Organovo, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
US10626081B2
(en)
|
2015-09-16 |
2020-04-21 |
Metacrine, Inc. |
Farnesoid X receptor agonists and uses thereof
|
|
EP3350166A4
(en)
|
2015-09-16 |
2019-05-01 |
Metacrine, Inc. |
FARNESOID-X RECEPTOR AGONISTS AND USES THEREOF
|
|
BR112018006471B1
(pt)
|
2015-10-01 |
2024-02-27 |
Senomyx, Inc |
Composto, composição, método de modular o membro de melastina do canal potencial do receptor transitório 8 (trpm8), método de modular a sensação de resfrescância de uma composição e método de induzir uma sensação de refrescância em um ser humano ou animal
|
|
CN105477636B
(zh)
|
2015-10-16 |
2019-09-17 |
厦门大学 |
使用阿维菌素及其衍生物治疗代谢疾病的方法
|
|
WO2017078928A1
(en)
|
2015-11-06 |
2017-05-11 |
Salk Institute For Biological Studies |
Fxr agonists and methods for making and using
|
|
CN107126419B
(zh)
|
2016-02-26 |
2020-06-19 |
石药集团中诺药业（石家庄）有限公司 |
一种奥贝胆酸片剂及其制备方法
|
|
KR102316645B1
(ko)
|
2016-03-31 |
2021-10-25 |
가부시키가이샤 아데카 |
감광성 조성물 및 신규 화합물
|
|
DK3596053T3
(da)
*
|
2017-03-15 |
2023-09-25 |
Organovo Inc |
Farnesoid-x-receptoragonister og anvendelser deraf
|
|
WO2018170173A1
(en)
|
2017-03-15 |
2018-09-20 |
Metacrine, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
AU2018236275B2
(en)
*
|
2017-03-15 |
2022-05-12 |
Eli Lilly And Company |
Farnesoid X receptor agonists and uses thereof
|
|
US20200131132A1
(en)
|
2017-03-15 |
2020-04-30 |
Metacrine, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
WO2018170165A1
(en)
|
2017-03-15 |
2018-09-20 |
Metacrine, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
CZ2017298A3
(cs)
|
2017-05-26 |
2018-12-05 |
Zentiva, K.S. |
Amorfní formy obeticholové kyseliny
|
|
WO2020060007A1
(ko)
|
2018-09-17 |
2020-03-26 |
엘지전자 주식회사 |
5g 이동통신에서 pdu 세션을 핸들링하는 방법 및 무선 기기
|
|
US20220047553A1
(en)
|
2018-09-18 |
2022-02-17 |
Metacrine, Inc. |
Farnesoid x receptor agonists for the treatment of disease
|
|
BR112021004931A2
(pt)
|
2018-09-18 |
2021-06-01 |
Metacrine, Inc. |
formas cristalinas de um agonista de receptor farnesoide x
|
|
WO2020061117A1
(en)
*
|
2018-09-18 |
2020-03-26 |
Metacrine, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
CN113056264A
(zh)
*
|
2018-09-18 |
2021-06-29 |
梅塔科林公司 |
法尼醇x受体激动剂及其用途
|
|
EP3852748B1
(en)
*
|
2018-09-18 |
2025-09-03 |
Eli Lilly and Company |
Farnesoid x receptor agonists and uses thereof
|
|
WO2020061118A1
(en)
|
2018-09-18 |
2020-03-26 |
Metacrine, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
WO2020061116A1
(en)
|
2018-09-18 |
2020-03-26 |
Metacrine, Inc. |
Farnesoid x receptor agonists and uses thereof
|
|
JP7664278B2
(ja)
|
2020-03-18 |
2025-04-17 |
オルガノボ，インク． |
ファルネソイドｘ受容体アゴニストの結晶質形態
|
|
CN120227340A
(zh)
|
2020-03-18 |
2025-07-01 |
伊莱利利公司 |
法尼醇x受体激动剂的制剂
|
|
KR20220154801A
(ko)
*
|
2020-03-18 |
2022-11-22 |
메타크린, 인크. |
질환의 치료를 위한 파르네소이드 x 수용체 작용제
|