MX2022011582A - Formas cristalinas de un agonista del receptor farnesoide x. - Google Patents

Formas cristalinas de un agonista del receptor farnesoide x.

Info

Publication number
MX2022011582A
MX2022011582A MX2022011582A MX2022011582A MX2022011582A MX 2022011582 A MX2022011582 A MX 2022011582A MX 2022011582 A MX2022011582 A MX 2022011582A MX 2022011582 A MX2022011582 A MX 2022011582A MX 2022011582 A MX2022011582 A MX 2022011582A
Authority
MX
Mexico
Prior art keywords
farnesoid
receptor agonist
crystalline forms
hydroxyazetidine
metho
Prior art date
Application number
MX2022011582A
Other languages
English (en)
Spanish (es)
Inventor
Nicholas D Smith
Robert Mansfield
Original Assignee
Metacrine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metacrine Inc filed Critical Metacrine Inc
Publication of MX2022011582A publication Critical patent/MX2022011582A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX2022011582A 2020-03-18 2021-03-17 Formas cristalinas de un agonista del receptor farnesoide x. MX2022011582A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062991213P 2020-03-18 2020-03-18
PCT/US2021/022790 WO2021188692A1 (en) 2020-03-18 2021-03-17 Crystalline forms of a farnesoid x receptor agonist

Publications (1)

Publication Number Publication Date
MX2022011582A true MX2022011582A (es) 2022-12-13

Family

ID=77771306

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2022011582A MX2022011582A (es) 2020-03-18 2021-03-17 Formas cristalinas de un agonista del receptor farnesoide x.
MX2025009319A MX2025009319A (es) 2020-03-18 2022-09-15 Formas cristalinas de un agonista del receptor farnesoide x

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2025009319A MX2025009319A (es) 2020-03-18 2022-09-15 Formas cristalinas de un agonista del receptor farnesoide x

Country Status (13)

Country Link
US (2) US12545660B2 (cg-RX-API-DMAC10.html)
EP (1) EP4121010A4 (cg-RX-API-DMAC10.html)
JP (2) JP7664278B2 (cg-RX-API-DMAC10.html)
KR (1) KR20220155356A (cg-RX-API-DMAC10.html)
CN (1) CN115666521A (cg-RX-API-DMAC10.html)
AR (1) AR121596A1 (cg-RX-API-DMAC10.html)
AU (1) AU2021236648A1 (cg-RX-API-DMAC10.html)
BR (1) BR112022018596A2 (cg-RX-API-DMAC10.html)
CA (1) CA3171987A1 (cg-RX-API-DMAC10.html)
IL (1) IL296532A (cg-RX-API-DMAC10.html)
MX (2) MX2022011582A (cg-RX-API-DMAC10.html)
TW (1) TW202144332A (cg-RX-API-DMAC10.html)
WO (1) WO2021188692A1 (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3852748B1 (en) * 2018-09-18 2025-09-03 Eli Lilly and Company Farnesoid x receptor agonists and uses thereof
CN120227340A (zh) 2020-03-18 2025-07-01 伊莱利利公司 法尼醇x受体激动剂的制剂
JP7664278B2 (ja) 2020-03-18 2025-04-17 オルガノボ，インク． ファルネソイドｘ受容体アゴニストの結晶質形態

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Also Published As

Publication number Publication date
TW202144332A (zh) 2021-12-01
AR121596A1 (es) 2022-06-22
EP4121010A1 (en) 2023-01-25
KR20220155356A (ko) 2022-11-22
MX2025009319A (es) 2025-09-02
US20230147756A1 (en) 2023-05-11
US12545660B2 (en) 2026-02-10
JP2025121901A (ja) 2025-08-20
CA3171987A1 (en) 2021-09-23
US20260226028A1 (en) 2026-08-06
AU2021236648A1 (en) 2022-10-13
WO2021188692A1 (en) 2021-09-23
JP2023518399A (ja) 2023-05-01
EP4121010A4 (en) 2024-04-10
IL296532A (en) 2022-11-01
BR112022018596A2 (pt) 2023-03-07
JP7664278B2 (ja) 2025-04-17
CN115666521A (zh) 2023-01-31

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