JP2023516632A5 - - Google Patents
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- Publication number
- JP2023516632A5 JP2023516632A5 JP2022552125A JP2022552125A JP2023516632A5 JP 2023516632 A5 JP2023516632 A5 JP 2023516632A5 JP 2022552125 A JP2022552125 A JP 2022552125A JP 2022552125 A JP2022552125 A JP 2022552125A JP 2023516632 A5 JP2023516632 A5 JP 2023516632A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- concentration
- cell
- induction medium
- bulk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062983511P | 2020-02-28 | 2020-02-28 | |
| US62/983,511 | 2020-02-28 | ||
| PCT/US2021/019917 WO2021174004A1 (en) | 2020-02-28 | 2021-02-26 | Method for producing natural killer cells from pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023516632A JP2023516632A (ja) | 2023-04-20 |
| JP2023516632A5 true JP2023516632A5 (https=) | 2024-03-05 |
| JP7778708B2 JP7778708B2 (ja) | 2025-12-02 |
Family
ID=75108897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022552125A Active JP7778708B2 (ja) | 2020-02-28 | 2021-02-26 | 多能性幹細胞からナチュラルキラー細胞を産生するための方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US12351824B2 (https=) |
| EP (1) | EP4110904A1 (https=) |
| JP (1) | JP7778708B2 (https=) |
| KR (1) | KR20220148174A (https=) |
| CN (1) | CN115427555A (https=) |
| AR (1) | AR121455A1 (https=) |
| AU (1) | AU2021225952A1 (https=) |
| BR (1) | BR112022017216A2 (https=) |
| CA (1) | CA3169617A1 (https=) |
| CO (1) | CO2022011682A2 (https=) |
| IL (1) | IL295964A (https=) |
| MX (1) | MX2022010521A (https=) |
| TW (1) | TWI886220B (https=) |
| WO (1) | WO2021174004A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| CN113801846B (zh) * | 2021-09-22 | 2024-06-04 | 南京艾尔普再生医学科技有限公司 | 一种从人诱导多能干细胞分化为自然杀伤细胞的方法 |
| CN114350608B (zh) * | 2022-01-27 | 2024-05-28 | 昭泰英基生物医药（香港）有限公司 | 一种诱导t细胞重编程为类nk细胞的组合物及其应用 |
| CN114517176B (zh) * | 2022-01-27 | 2022-12-02 | 广东普罗凯融生物医药科技有限公司 | 一种将ips细胞诱导成nk细胞的试剂盒及其应用方法 |
| JPWO2024004960A1 (https=) | 2022-06-27 | 2024-01-04 | ||
| WO2024101862A1 (ko) * | 2022-11-07 | 2024-05-16 | 마루테라퓨틱스 주식회사 | Nk 세포의 분화 효율 및 기능성 증가를 위한 배양 방법 |
| WO2024107010A1 (ko) * | 2022-11-17 | 2024-05-23 | 주식회사 씨티셀즈 | 미분화 줄기세포로부터 자연 살해 세포로의 분화 방법 및 이의 용도 |
| CN115537397B (zh) * | 2022-12-02 | 2023-03-24 | 广东先康达细胞库有限公司 | Nk细胞诱导培养基及其培养方法 |
| CN118667760A (zh) * | 2023-03-17 | 2024-09-20 | 深圳市三启生物技术有限公司 | 诱导多能干细胞分化为cd34+造血干/祖细胞的培养基组合 |
| AU2024263914A1 (en) * | 2023-04-27 | 2025-12-04 | Takeda Pharmaceutical Company Limited | Method for expanding cd56+/cd3- cells |
| CN116410336B (zh) * | 2023-06-02 | 2023-09-22 | 云南赛元生物技术有限公司 | 一种嵌合抗原受体的编码核苷酸、car-nk细胞及其构建方法和应用 |
| CN117050941B (zh) * | 2023-10-11 | 2024-01-26 | 苏州艾凯利元生物科技有限公司 | 一种制备自然杀伤细胞的方法 |
| CN117050940B (zh) * | 2023-10-11 | 2024-01-26 | 苏州艾凯利元生物科技有限公司 | 一种制备自然杀伤细胞的方法 |
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| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US9453219B2 (en) | 2003-05-15 | 2016-09-27 | Mello Biotech Taiwan Co., Ltd. | Cosmetic designs and products using intronic RNA |
| US8048999B2 (en) | 2005-12-13 | 2011-11-01 | Kyoto University | Nuclear reprogramming factor |
| JP5813321B2 (ja) | 2007-03-23 | 2015-11-17 | ウィスコンシン アラムニ リサーチ ファンデーション | 体細胞の再プログラム化 |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| ES2799897T3 (es) | 2007-08-31 | 2020-12-22 | Whitehead Inst Biomedical Res | Estimulación de la vía wnt en la reprogramación de células somáticas |
| KR101564044B1 (ko) | 2007-10-31 | 2015-10-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 핵초기화 방법 |
| JP5558097B2 (ja) | 2007-12-10 | 2014-07-23 | 国立大学法人京都大学 | 効率的な核初期化方法 |
| WO2009079007A1 (en) | 2007-12-17 | 2009-06-25 | Gliamed, Inc. | Stem-like cells and method for reprogramming adult mammalian somatic cells |
| WO2009091659A2 (en) | 2008-01-16 | 2009-07-23 | Shi-Lung Lin | Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant rna agents |
| US20100330677A1 (en) | 2008-02-11 | 2010-12-30 | Cambridge Enterprise Limited | Improved Reprogramming of Mammalian Cells, and Cells Obtained |
| EP2090649A1 (en) | 2008-02-13 | 2009-08-19 | Fondazione Telethon | Method for reprogramming differentiated cells |
| WO2009102983A2 (en) | 2008-02-15 | 2009-08-20 | President And Fellows Of Harvard College | Efficient induction of pluripotent stem cells using small molecule compounds |
| MX2010010165A (es) | 2008-03-17 | 2010-11-25 | Scripps Research Inst | Procedimientos quimicos y geneticos combinados para generacion de celulas madre pluripotentes inducidas. |
| WO2009114949A1 (en) | 2008-03-20 | 2009-09-24 | UNIVERSITé LAVAL | Methods for deprogramming somatic cells and uses thereof |
| KR20110019727A (ko) | 2008-04-07 | 2011-02-28 | 뉴포텐셜, 인크. | Ｒｎａ 간섭을 통한 다능 유전자의 유도에 의한 세포 재프로그래밍 |
| CA2695590C (en) | 2008-06-27 | 2018-01-09 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| US9453204B2 (en) | 2008-07-14 | 2016-09-27 | Oklahoma Medical Research Foundation | Production of pluripotent cells through inhibition of bright/ARID3a function |
| WO2010147612A1 (en) | 2009-06-18 | 2010-12-23 | Lixte Biotechnology, Inc. | Methods of modulating cell regulation by inhibiting p53 |
| WO2010033920A2 (en) | 2008-09-19 | 2010-03-25 | Whitehead Institute For Biomedical Research | Compositions and methods for enhancing cell reprogramming |
| US20120021519A1 (en) | 2008-09-19 | 2012-01-26 | Presidents And Fellows Of Harvard College | Efficient induction of pluripotent stem cells using small molecule compounds |
| WO2010042800A1 (en) | 2008-10-10 | 2010-04-15 | Nevada Cancer Institute | Methods of reprogramming somatic cells and methods of use for such cells |
| JP2012507258A (ja) | 2008-10-30 | 2012-03-29 | 国立大学法人京都大学 | 人工多能性幹細胞の作製方法 |
| US20110059526A1 (en) | 2008-11-12 | 2011-03-10 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through use of an hdac modulator |
| EP2376626A4 (en) | 2008-12-13 | 2012-10-17 | Dna Microarray | MICRO-ENVIRONMENTAL NICHE ASSAY FOR SCREENING OF INDUCED PLURIPOTENT STEM CELLS (CIPS) |
| WO2010098419A1 (en) | 2009-02-27 | 2010-09-02 | Kyoto University | Novel nuclear reprogramming substance |
| WO2010102267A2 (en) | 2009-03-06 | 2010-09-10 | Ipierian, Inc. | Tgf-beta pathway inhibitors for enhancement of cellular reprogramming of human cells |
| US20120076762A1 (en) | 2009-03-25 | 2012-03-29 | The Salk Institute For Biological Studies | Induced pluripotent stem cell generation using two factors and p53 inactivation |
| WO2010111409A2 (en) | 2009-03-25 | 2010-09-30 | The Salk Institute For Biological Studies | Pluripotent stem cells |
| WO2010115050A2 (en) | 2009-04-01 | 2010-10-07 | The Regents Of The University Of California | Embryonic stem cell specific micrornas promote induced pluripotency |
| WO2010124290A2 (en) | 2009-04-24 | 2010-10-28 | Whitehead Institute For Biomedical Research | Compositions and methods for deriving or culturing pluripotent cells |
| WO2010147395A2 (en) | 2009-06-16 | 2010-12-23 | Korea Research Institute Of Bioscience And Biotechnology | Medium composition comprising neuropeptide y for the generation, maintenance, prologned undifferentiated growth of pluripotent stem cells and method of culturing pluripotent stem cell using the same |
| EP3184109B1 (en) | 2009-12-29 | 2020-11-18 | Gamida-Cell Ltd. | Methods for enhancing natural killer cell proliferation and activity |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| WO2016123100A1 (en) | 2015-01-26 | 2016-08-04 | Fate Therapeutics, Inc. | Methods and compositions for inducing hematopoietic cell differentiation |
| US10669528B2 (en) * | 2015-06-25 | 2020-06-02 | Children's Medical Center Corporation | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance |
| US10947502B2 (en) | 2015-10-20 | 2021-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
| SG11201803145RA (en) * | 2015-11-04 | 2018-05-30 | Fate Therapeutics Inc | Methods and compositions for inducing hematopoietic cell differentiation |
| US11578310B2 (en) | 2016-06-23 | 2023-02-14 | Kyoto University | Method for producing CD4/CD8 double-positive T cells |
| SG11201909331UA (en) | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Antigen-specific immune effector cells |
-
2021
- 2021-02-26 US US17/186,877 patent/US12351824B2/en active Active
- 2021-02-26 IL IL295964A patent/IL295964A/en unknown
- 2021-02-26 TW TW110107162A patent/TWI886220B/zh active
- 2021-02-26 KR KR1020227028995A patent/KR20220148174A/ko active Pending
- 2021-02-26 MX MX2022010521A patent/MX2022010521A/es unknown
- 2021-02-26 JP JP2022552125A patent/JP7778708B2/ja active Active
- 2021-02-26 CA CA3169617A patent/CA3169617A1/en active Pending
- 2021-02-26 WO PCT/US2021/019917 patent/WO2021174004A1/en not_active Ceased
- 2021-02-26 EP EP21713302.4A patent/EP4110904A1/en active Pending
- 2021-02-26 CN CN202180017317.4A patent/CN115427555A/zh active Pending
- 2021-02-26 AU AU2021225952A patent/AU2021225952A1/en active Pending
- 2021-02-26 BR BR112022017216A patent/BR112022017216A2/pt unknown
- 2021-02-26 AR ARP210100517A patent/AR121455A1/es unknown
-
2022
- 2022-08-19 CO CONC2022/0011682A patent/CO2022011682A2/es unknown
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