JP2023511524A5 - - Google Patents

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Publication number
JP2023511524A5
JP2023511524A5 JP2022540698A JP2022540698A JP2023511524A5 JP 2023511524 A5 JP2023511524 A5 JP 2023511524A5 JP 2022540698 A JP2022540698 A JP 2022540698A JP 2022540698 A JP2022540698 A JP 2022540698A JP 2023511524 A5 JP2023511524 A5 JP 2023511524A5
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JP
Japan
Application number
JP2022540698A
Other languages
Japanese (ja)
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JP2023511524A (ja
JPWO2021148610A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/051466 external-priority patent/WO2021148610A1/en
Publication of JP2023511524A publication Critical patent/JP2023511524A/ja
Publication of JP2023511524A5 publication Critical patent/JP2023511524A5/ja
Publication of JPWO2021148610A5 publication Critical patent/JPWO2021148610A5/ja
Pending legal-status Critical Current

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JP2022540698A 2020-01-23 2021-01-22 Hmo産生 Pending JP2023511524A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA202000088 2020-01-23
DKPA202000088 2020-01-23
PCT/EP2021/051466 WO2021148610A1 (en) 2020-01-23 2021-01-22 Hmo production

Publications (3)

Publication Number Publication Date
JP2023511524A JP2023511524A (ja) 2023-03-20
JP2023511524A5 true JP2023511524A5 (https=) 2023-09-22
JPWO2021148610A5 JPWO2021148610A5 (https=) 2023-09-22

Family

ID=74505190

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022540698A Pending JP2023511524A (ja) 2020-01-23 2021-01-22 Hmo産生

Country Status (6)

Country Link
US (1) US20230109661A1 (https=)
EP (1) EP4093748A1 (https=)
JP (1) JP2023511524A (https=)
CN (1) CN114981291B (https=)
BR (1) BR112022014420A2 (https=)
WO (1) WO2021148610A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK181497B1 (en) 2021-05-17 2024-03-12 Dsm Ip Assets Bv ENHANCING FORMATION OF THE HMOS LNT AND/OR LNnT BY MODIFYING LACTOSE IMPORT IN THE CELL
DK181991B1 (en) 2021-11-11 2025-05-15 Dsm Ip Assets Bv Combined fermentation process for producing one or more human milk oligosaccharide(s) (hmo(s)) in escherichia coli
US20260028634A1 (en) 2022-03-02 2026-01-29 Dsm Ip Assets B.V. New sialyltransferases for in vivo synthesis of 3'sl and 6'sl
DK181319B1 (en) 2022-03-02 2023-08-10 Dsm Ip Assets Bv Genetically engineered cells and methods comprising use of a sialyltransferase for in vivo synthesis of 3’sl
DK181683B1 (en) 2022-03-02 2024-09-20 Dsm Ip Assets Bv Cells exprssing new sialyltransferases for in vivo synthesis of lst-a, methods using same and constructs encoding said sialyltransferases
US20250290078A1 (en) 2022-04-29 2025-09-18 Dsm Ip Assets B.V. Hmo producing microorganism with increased robustness towards glucose gradients
EP4577061A1 (en) 2022-08-25 2025-07-02 DSM IP Assets B.V. Hybrid method for producing complex hmos
WO2024110667A1 (en) 2022-11-25 2024-05-30 Dsm Ip Assets B.V. Two-strain system for producing oligosaccharides
CN120677242A (zh) 2023-02-24 2025-09-19 帝斯曼知识产权资产管理有限公司 用于体内合成人乳寡糖的产物特异性转运蛋白
DK181822B1 (en) 2023-06-07 2025-01-30 Dsm Ip Assets Bv Genetically engineered strains with reduced byproduct formation and methods and uses of same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2440661T3 (en) * 2009-06-08 2018-03-12 Jennewein Biotechnologie Gmbh HMO synthesis
EP2675899A4 (en) 2011-02-16 2014-09-10 Glycosyn LLC BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN MANIPULATED BACTERIA
EP3461890B1 (en) * 2014-03-31 2025-09-24 Chr. Hansen HMO GmbH Total fermentation of oligosaccharides
DE202015009782U1 (de) 2014-06-11 2020-02-10 Glycom A/S Trennung von 2'-O-Fucosyllactose aus Fermentationsbrühe
EP3191499A4 (en) 2014-09-09 2018-06-06 Glycosyn LLC Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides
US10676770B2 (en) 2014-12-16 2020-06-09 Glycom A/S Separation of 2′-FL from a fermentation broth
EP3141610A1 (en) 2015-09-12 2017-03-15 Jennewein Biotechnologie GmbH Production of human milk oligosaccharides in microbial hosts with engineered import / export
DE202017007249U1 (de) 2016-03-07 2020-04-23 Glycom A/S Abtrennung von Oligosacchariden aus der Fermentationsbrühe
EP4674526A3 (en) 2016-04-19 2026-04-01 Glycom A/S Separation of oligosaccharides from fermentation broth
ES2856749T3 (es) 2016-10-29 2021-09-28 Chr Hansen Hmo Gmbh Proceso para la producción de oligosacáridos fucosilados
US11608504B2 (en) * 2017-12-21 2023-03-21 Glycom A/S Nucleic acid construct for in vitro and in vivo gene expression
US20190323053A1 (en) 2018-04-23 2019-10-24 Dupont Nutrition Biosciences Aps Increasing activity of 2? fucosyllactose transporters endogenous to microbial cells
US20190323052A1 (en) 2018-04-23 2019-10-24 Dupont Nutrition Biosciences Aps Increasing export of 2? fucosyllactose from microbial cells through the expression of a heterologous nucleic acid
EP3569713A1 (en) * 2018-05-16 2019-11-20 Jennewein Biotechnologie GmbH Use of glycosidases in the production of oligosaccharides
US10519475B1 (en) 2018-11-21 2019-12-31 Amyris, Inc. Biosynthesis of compounds in yeast

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