PL2927316T3 - Całkowita fermentacja oligosacharydów - Google Patents
Całkowita fermentacja oligosacharydówInfo
- Publication number
- PL2927316T3 PL2927316T3 PL14162869T PL14162869T PL2927316T3 PL 2927316 T3 PL2927316 T3 PL 2927316T3 PL 14162869 T PL14162869 T PL 14162869T PL 14162869 T PL14162869 T PL 14162869T PL 2927316 T3 PL2927316 T3 PL 2927316T3
- Authority
- PL
- Poland
- Prior art keywords
- oligosaccharides
- total fermentation
- fermentation
- total
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14162869.3A EP2927316B1 (en) | 2014-03-31 | 2014-03-31 | Total fermentation of oligosaccharides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2927316T3 true PL2927316T3 (pl) | 2019-05-31 |
Family
ID=50389365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14162869T PL2927316T3 (pl) | 2014-03-31 | 2014-03-31 | Całkowita fermentacja oligosacharydów |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP3461890A1 (pl) |
| JP (1) | JP6360908B2 (pl) |
| KR (1) | KR102012070B1 (pl) |
| DK (1) | DK2927316T3 (pl) |
| ES (1) | ES2715010T3 (pl) |
| PL (1) | PL2927316T3 (pl) |
| WO (1) | WO2015150328A1 (pl) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3098403C (en) | 2011-02-16 | 2022-05-10 | Glycosyn LLC | Biosynthesis of human milk oligosaccharides in engineered bacteria |
| PL2896628T3 (pl) | 2014-01-20 | 2019-03-29 | Jennewein Biotechnologie Gmbh | Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej |
| SG11201609366TA (en) * | 2014-05-15 | 2016-12-29 | Glycosyn LLC | Alpha (1,2) fucosyltransferase syngenes for use in the production of fucosylated oligosaccharides |
| WO2015197082A1 (en) | 2014-06-27 | 2015-12-30 | Glycom A/S | Oligosaccharide production |
| US11926858B2 (en) | 2014-06-27 | 2024-03-12 | Glycom A/S | Oligosaccharide production |
| EP3141610A1 (en) * | 2015-09-12 | 2017-03-15 | Jennewein Biotechnologie GmbH | Production of human milk oligosaccharides in microbial hosts with engineered import / export |
| EP3390652A4 (en) | 2015-12-18 | 2019-06-12 | Glycom A/S | Fermentative preparation of oligosaccharides |
| US11312741B2 (en) | 2016-04-19 | 2022-04-26 | Glycom A/S | Separation of oligosaccharides from fermentation broth |
| KR101731263B1 (ko) * | 2016-04-25 | 2017-05-02 | 서울대학교 산학협력단 | 코리네박테리움 글루타미쿰을 이용한 2'-푸코실락토오스의 생산방법 |
| DK3315610T3 (da) | 2016-10-29 | 2021-03-08 | Jennewein Biotechnologie Gmbh | Fremgangsmåde til fremstilling af fucosylerede oligosaccharider |
| CN108611344A (zh) * | 2016-12-10 | 2018-10-02 | 中国科学院大连化学物理研究所 | AtAGM2与AtAGM3编码基因及酶的制备与应用 |
| WO2018122225A1 (en) * | 2016-12-27 | 2018-07-05 | Inbiose N.V. | In vivo synthesis of sialylated compounds |
| DK3375291T3 (da) * | 2017-03-17 | 2022-10-31 | Chr Hansen Hmo Gmbh | Fremgangsmåde til hæmning af isomerisering af et reducerende saccharid efter termisk behandling |
| KR102050522B1 (ko) * | 2017-04-21 | 2020-01-08 | 서울대학교산학협력단 | 코리네박테리움 글루타미쿰을 이용한 3'-푸코실락토오스의 생산방법 |
| MX2019015526A (es) * | 2017-06-30 | 2020-09-10 | Zimitech Inc | Microorganismos modificados para el uso mejorado de oligosacáridos. |
| US20200123184A1 (en) | 2017-06-30 | 2020-04-23 | Glycom A/S | Purification of oligosaccharides |
| EP3425052A1 (en) | 2017-07-07 | 2019-01-09 | Jennewein Biotechnologie GmbH | Fucosyltransferases and their use in producing fucosylated oligosaccharides |
| CN110914284A (zh) | 2017-07-12 | 2020-03-24 | 格礼卡姆股份公司 | 包含中性单糖或寡糖和酸性非碳水化合物组分的无定形混合物 |
| BR112020001628A2 (pt) * | 2017-07-26 | 2020-07-21 | Jennewein Biotechnologie Gmbh | sialiltransferases e uso das mesmas na produção de oligossacarídeos sialilados |
| EP3450443A1 (en) * | 2017-08-29 | 2019-03-06 | Jennewein Biotechnologie GmbH | Process for purifying sialylated oligosaccharides |
| EP3494806A1 (en) | 2017-12-08 | 2019-06-12 | Jennewein Biotechnologie GmbH | Spray-dried lacto-n-fucopentaose |
| EP3494804A1 (en) | 2017-12-08 | 2019-06-12 | Jennewein Biotechnologie GmbH | Spray-dried 3-fucosyllactose |
| JP2021505171A (ja) | 2017-12-08 | 2021-02-18 | イェンネワイン バイオテクノロジー ゲーエムベーハーＪｅｎｎｅｗｅｉｎ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅ ＧｍｂＨ | 噴霧乾燥シアリルラクトース |
| EP3494807A1 (en) | 2017-12-11 | 2019-06-12 | Jennewein Biotechnologie GmbH | Spray-dried sialyllactose |
| EP3524067A1 (en) | 2018-02-08 | 2019-08-14 | Jennewein Biotechnologie GmbH | Spray-dried mixture of human milk oligosaccharides |
| EP3494805A1 (en) | 2017-12-08 | 2019-06-12 | Jennewein Biotechnologie GmbH | Spray-dried tetrasaccharides |
| CN108410787A (zh) * | 2018-03-13 | 2018-08-17 | 光明乳业股份有限公司 | 一种合成乳酰-n-新四糖的重组枯草芽孢杆菌及其构建方法与应用 |
| WO2019209241A1 (en) * | 2018-04-23 | 2019-10-31 | Dupont Nutrition Biosciences Aps | Increasing export of 2' fucosyllactose from microbial cells through the expression of a heterologous nucleic acid |
| US20210071134A1 (en) * | 2018-04-23 | 2021-03-11 | Dupont Nutrition Biosciences Aps | Increasing activity of 2'fucosyllactose transporters endogenous to microbial cells |
| EP3569713A1 (en) * | 2018-05-16 | 2019-11-20 | Jennewein Biotechnologie GmbH | Use of glycosidases in the production of oligosaccharides |
| CN109554385B (zh) * | 2018-07-24 | 2022-04-12 | 石家庄葛兰德生物科技有限公司 | 一种基因工程菌制备2-岩藻糖基乳糖的方法 |
| ES2965229T3 (es) | 2018-09-06 | 2024-04-11 | Chr Hansen Hmo Gmbh | Producción fermentativa de oligosacáridos mediante fermentación total usando una materia prima mixta |
| EP3853372A1 (en) | 2018-09-21 | 2021-07-28 | Universiteit Gent | Method for the production of amino sugar containing products |
| BR112021010116A2 (pt) * | 2018-12-04 | 2021-08-31 | Glycom A/S | Síntese do oligossacarídeo fucosilado lnfp-v |
| EP3702468A1 (en) * | 2019-03-01 | 2020-09-02 | Jennewein Biotechnologie GmbH | Fermentative production of carbohydrates by microbial cells utilizing a mixed feedstock |
| CN114364389A (zh) | 2019-09-24 | 2022-04-15 | 普罗莱克塔生物科学公司 | 用于治疗炎性和免疫疾病的组合物和方法 |
| CN110804577B (zh) * | 2019-11-28 | 2021-05-28 | 江南大学 | 一种高效生产2’-岩藻糖基乳糖的重组菌的构建方法及其应用 |
| CN110885364B (zh) * | 2019-12-26 | 2021-02-02 | 江南大学 | 一种促进N-乙酰氨基葡萄糖生产的RamA转录因子突变体及其应用 |
| BR112022014420A2 (pt) * | 2020-01-23 | 2022-09-27 | Glycom As | Produção de hmo |
| CN115003812A (zh) * | 2020-01-23 | 2022-09-02 | 格礼卡姆股份公司 | Hmo生产中的新的主要易化因子超家族(mfs)蛋白质(bad) |
| BR112022014376A2 (pt) * | 2020-01-23 | 2022-10-04 | Glycom As | Nova proteína da superfamília de facilitadores principais (mfs) (fred) na produção de hmo |
| AU2021210607A1 (en) * | 2020-01-23 | 2022-07-14 | Glycom A/S | HMO production |
| WO2021160830A1 (en) | 2020-02-14 | 2021-08-19 | Inbiose N.V. | Glycominimized bacterial host cells |
| US20220396817A1 (en) | 2020-02-14 | 2022-12-15 | Inbiose N.V. | Production of glycosylated product in host cells |
| WO2022013143A1 (en) | 2020-07-13 | 2022-01-20 | Glycom A/S | Oligosaccharide production |
| CN116234919A (zh) * | 2020-08-10 | 2023-06-06 | 因比奥斯公司 | 借由细胞制造中性岩藻糖基化寡糖的混合物 |
| WO2022036225A1 (en) | 2020-08-14 | 2022-02-17 | Prolacta Bioscience, Inc. | Human milk oligosaccharide compositions for use with bacteriotherapies |
| CA3204530A1 (en) | 2021-01-12 | 2022-07-21 | Gregory Mckenzie | Synbiotic treatment regimens |
| JP2024505126A (ja) * | 2021-01-22 | 2024-02-05 | グリコム・アクティーゼルスカブ | シアル酸付加ｈｍｏの産生における新規の主要ファシリテータースーパーファミリー（ｍｆｓ）タンパク質（ｆｒｅｄ） |
| EP4043572A1 (en) * | 2021-02-11 | 2022-08-17 | GALAB Laboratories GmbH | Glycosyltransferase deficient corynebacterium for the production of fucosyllactose |
| EP4043571A1 (en) * | 2021-02-11 | 2022-08-17 | GALAB Laboratories GmbH | Genetically modified corynebacterium for the production of fucosyllactose |
| DK181497B1 (en) | 2021-05-17 | 2024-03-12 | Dsm Ip Assets Bv | ENHANCING FORMATION OF THE HMOS LNT AND/OR LNnT BY MODIFYING LACTOSE IMPORT IN THE CELL |
| CN113684164B (zh) * | 2021-08-06 | 2023-08-25 | 江南大学 | 一种高产乳酰-n-新四糖的微生物的构建方法及应用 |
| WO2024013348A1 (en) | 2022-07-15 | 2024-01-18 | Dsm Ip Assets B.V. | New fucosyltransferases for in vivo synthesis of complex fucosylated human milk oligosaccharides |
| CN115058369B (zh) * | 2022-07-20 | 2024-02-20 | 威海迪普森生物科技有限公司 | 一种胞外多糖来源岩藻寡糖发酵型合生元的制备方法 |
| WO2024042235A1 (en) | 2022-08-25 | 2024-02-29 | Dsm Ip Assets B.V. | Hybrid method for producing complex hmos |
| WO2024046993A1 (en) | 2022-08-29 | 2024-03-07 | Chr. Hansen A/S | Process for the production of a purified human milk oligosaccharide derived from a microbial fermentation process |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6699705B2 (en) * | 1999-02-01 | 2004-03-02 | National Research Council Of Canada | Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics |
| FR2796082B1 (fr) * | 1999-07-07 | 2003-06-27 | Centre Nat Rech Scient | Procede de production d'oligosaccharides |
| US20080145899A1 (en) | 2004-09-17 | 2008-06-19 | Neose Technologies Inc | Production of Oligosaccharides By Microorganisms |
| KR101083136B1 (ko) * | 2009-02-13 | 2011-11-11 | 씨제이제일제당 (주) | Ｌ-아미노산 생산용 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법 |
| RU2517602C2 (ru) * | 2009-06-08 | 2014-05-27 | Йенневайн Биотехнологи Гмбх | Синтез нмо |
| EP3235907B1 (en) * | 2010-07-12 | 2023-06-21 | Inbiose N.V. | Metabolically engineered organisms for the production of added value bio-products |
| ES2663627T3 (es) | 2010-10-11 | 2018-04-16 | Jennewein Biotechnologie Gmbh | Fucosiltransferasas novedosas y sus aplicaciones |
| DK2479263T3 (da) | 2011-01-20 | 2014-02-03 | Jennewein Biotechnologie Gmbh | Nye fucosyltransferaser og deres anvendelser |
| CA3098403C (en) * | 2011-02-16 | 2022-05-10 | Glycosyn LLC | Biosynthesis of human milk oligosaccharides in engineered bacteria |
| WO2013182206A1 (en) * | 2012-06-08 | 2013-12-12 | Glycom A/S | Method for producing oligosaccharides and oligosaccharide glycosides by fermentation |
-
2014
- 2014-03-31 EP EP18204608.6A patent/EP3461890A1/en active Pending
- 2014-03-31 ES ES14162869T patent/ES2715010T3/es active Active
- 2014-03-31 EP EP14162869.3A patent/EP2927316B1/en active Active
- 2014-03-31 DK DK14162869.3T patent/DK2927316T3/en active
- 2014-03-31 PL PL14162869T patent/PL2927316T3/pl unknown
-
2015
- 2015-03-30 KR KR1020167030326A patent/KR102012070B1/ko active IP Right Grant
- 2015-03-30 WO PCT/EP2015/056901 patent/WO2015150328A1/en active Application Filing
- 2015-03-30 JP JP2016559830A patent/JP6360908B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2927316B1 (en) | 2018-11-07 |
| EP2927316A1 (en) | 2015-10-07 |
| KR102012070B1 (ko) | 2019-08-19 |
| DK2927316T3 (en) | 2019-03-04 |
| JP2017509346A (ja) | 2017-04-06 |
| JP6360908B2 (ja) | 2018-07-18 |
| EP3461890A1 (en) | 2019-04-03 |
| ES2715010T3 (es) | 2019-05-31 |
| KR20170003546A (ko) | 2017-01-09 |
| WO2015150328A1 (en) | 2015-10-08 |
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