JP2023510854A - 小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用 - Google Patents

小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用 Download PDF

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JP2023510854A
JP2023510854A JP2022542743A JP2022542743A JP2023510854A JP 2023510854 A JP2023510854 A JP 2023510854A JP 2022542743 A JP2022542743 A JP 2022542743A JP 2022542743 A JP2022542743 A JP 2022542743A JP 2023510854 A JP2023510854 A JP 2023510854A
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antibody
weeks
hae
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ナース，クリスティーナ
ハオ，ピンイン
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Takeda Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2022542743A 2020-01-13 2021-01-12 小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用 Pending JP2023510854A (ja)

Priority Applications (1)

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JP2025157824A JP2025186458A (ja) 2020-01-13 2025-09-24 小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用

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US202062960333P 2020-01-13 2020-01-13
US62/960,333 2020-01-13
PCT/US2021/013035 WO2021146160A1 (en) 2020-01-13 2021-01-12 Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack

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JP2025157824A Division JP2025186458A (ja) 2020-01-13 2025-09-24 小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用

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JP2023510854A true JP2023510854A (ja) 2023-03-15
JP2023510854A5 JP2023510854A5 (https=) 2023-12-18

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JP2022542743A Pending JP2023510854A (ja) 2020-01-13 2021-01-12 小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用
JP2025157824A Pending JP2025186458A (ja) 2020-01-13 2025-09-24 小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用

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US (1) US12528880B2 (https=)
EP (1) EP4090427A1 (https=)
JP (2) JP2023510854A (https=)
KR (1) KR20220128379A (https=)
CN (1) CN115297927A (https=)
AU (1) AU2021209045A1 (https=)
CA (1) CA3167336A1 (https=)
MX (1) MX2022008649A (https=)
WO (1) WO2021146160A1 (https=)

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SMT201800552T1 (it) 2010-01-06 2018-11-09 Dyax Corp Proteine che legano la callicreina plasmatica
EA038532B1 (ru) 2014-01-21 2021-09-10 Такеда Фармасьютикал Компани Лимитед Способ лечения наследственного ангионевротического отека (hae)
US10428158B2 (en) 2014-03-27 2019-10-01 Dyax Corp. Compositions and methods for treatment of diabetic macular edema

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019501886A (ja) * 2015-12-11 2019-01-24 ダイアックス コーポレーション 遺伝性血管性浮腫の発作を治療するための血漿カリクレイン阻害薬およびその用途

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