JP2023162277A5 - - Google Patents

Info

Publication number
JP2023162277A5
JP2023162277A5 JP2023133410A JP2023133410A JP2023162277A5 JP 2023162277 A5 JP2023162277 A5 JP 2023162277A5 JP 2023133410 A JP2023133410 A JP 2023133410A JP 2023133410 A JP2023133410 A JP 2023133410A JP 2023162277 A5 JP2023162277 A5 JP 2023162277A5
Authority
JP
Japan
Prior art keywords
cells
population
rpe
enriched
positive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023133410A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023162277A (ja
Filing date
Publication date
Priority claimed from JP2018531311A external-priority patent/JP6986016B2/ja
Application filed filed Critical
Publication of JP2023162277A publication Critical patent/JP2023162277A/ja
Publication of JP2023162277A5 publication Critical patent/JP2023162277A5/ja
Pending legal-status Critical Current

Links

JP2023133410A 2015-09-08 2023-08-18 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製 Pending JP2023162277A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562215272P 2015-09-08 2015-09-08
US62/215,272 2015-09-08
JP2018531311A JP6986016B2 (ja) 2015-09-08 2016-09-07 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製
JP2021133999A JP2021184742A (ja) 2015-09-08 2021-08-19 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021133999A Division JP2021184742A (ja) 2015-09-08 2021-08-19 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製

Publications (2)

Publication Number Publication Date
JP2023162277A JP2023162277A (ja) 2023-11-08
JP2023162277A5 true JP2023162277A5 (https=) 2025-10-02

Family

ID=57045392

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018531311A Active JP6986016B2 (ja) 2015-09-08 2016-09-07 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製
JP2021133999A Pending JP2021184742A (ja) 2015-09-08 2021-08-19 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製
JP2023133410A Pending JP2023162277A (ja) 2015-09-08 2023-08-18 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2018531311A Active JP6986016B2 (ja) 2015-09-08 2016-09-07 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製
JP2021133999A Pending JP2021184742A (ja) 2015-09-08 2021-08-19 Ｍａｃｓを用いた幹細胞由来網膜色素上皮の精製

Country Status (11)

Country Link
US (3) US11162070B2 (https=)
EP (2) EP4001402A1 (https=)
JP (3) JP6986016B2 (https=)
KR (2) KR20260003355A (https=)
CN (2) CN114717188B (https=)
AU (1) AU2016318774B2 (https=)
CA (1) CA2997763A1 (https=)
DK (1) DK3347457T3 (https=)
ES (1) ES2903442T3 (https=)
LT (1) LT3347457T (https=)
WO (1) WO2017044488A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10485829B2 (en) 2009-11-17 2019-11-26 Astellas Institute For Regenerative Medicine Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells
WO2012149484A2 (en) 2011-04-29 2012-11-01 University Of Southern California Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate
WO2016063985A1 (ja) 2014-10-24 2016-04-28 大日本住友製薬株式会社 神経組織の製造方法
KR20260003355A (ko) 2015-09-08 2026-01-06 후지필름 셀룰러 다이내믹스, 인코포레이티드 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제
CN114807035B (zh) 2015-09-08 2024-02-02 (由卫生与公众服务部部长代表的)美利坚合众国 临床级别视网膜色素上皮细胞的可再现的分化方法
CN108431211B (zh) 2015-10-20 2026-03-24 富士胶片细胞动力公司 通过遗传编程的多谱系造血前体细胞产生
EP3402496A4 (en) * 2016-01-12 2019-06-19 Lonza Walkersville, Inc. METHOD AND VECTORS FOR PRODUCING VECTOR-FREE INDUCED PLURIPOTENTER STEM CELLS
SG11201809201UA (en) * 2016-04-22 2018-11-29 Sumitomo Dainippon Pharma Co Ltd Method for producing retinal tissue
MX2019006576A (es) 2016-12-07 2019-08-21 Mayo Found Medical Education & Res Metodos y materiales para usar soportes de fibrina para trasplante de epitelio de pigmento retiniano.
WO2018195175A1 (en) 2017-04-18 2018-10-25 FUJIFILM Cellular Dynamics, Inc. Antigen-specific immune effector cells
JP7311433B2 (ja) * 2017-06-05 2023-07-19 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 幹細胞を培養し、増殖させ、分化させるための方法及び材料
WO2018232258A1 (en) * 2017-06-15 2018-12-20 University Of North Texas Health Science Center Reprogramming fibroblasts to retinal cells
WO2019099552A1 (en) * 2017-11-14 2019-05-23 The J. David Gladstone Institutes Methods of generating retinal pigment epithelium (rpe)
KR102920569B1 (ko) * 2018-04-20 2026-02-02 후지필름 셀룰러 다이내믹스, 인코포레이티드 안구 세포의 분화를 위한 방법 및 이의 용도
WO2019213366A1 (en) * 2018-05-02 2019-11-07 The Trustees Of Columbia University In The City Of New York Methods to induce terminal differentiation in stem cells by interfering with dna replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof
PT4234024T (pt) * 2018-06-20 2026-01-21 Biolamina Ab Métodos e composições para produzir células do epitélio do pigmento da retina
WO2020051097A1 (en) * 2018-09-07 2020-03-12 University Of Southern California Cryopreservation of cell-seeded substrates and related methods
AU2019385332B2 (en) * 2018-11-19 2025-09-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Biodegradable tissue replacement implant and its use
MX2022004107A (es) 2019-10-09 2022-08-10 Bluerock Therapeutics Lp Celulas con expresion transgenica sostenida.
WO2021086911A1 (en) 2019-10-30 2021-05-06 Astellas Institute For Regenerative Medicine Methods for producing retinal pigment epithelium cells
BR112022024031A2 (pt) * 2020-05-29 2023-01-31 Fujifilm Cellular Dynamics Inc Agregados de células duplas de epitélio pigmentado da retina e fotorreceptor, e métodos de uso dos mesmos
TW202300642A (zh) 2021-03-25 2023-01-01 美商藍岩醫療公司 獲得誘導型多能幹細胞之方法
WO2022251499A1 (en) * 2021-05-28 2022-12-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods to generate macular, central and peripheral retinal pigment epithelial cells
CN115873797B (zh) * 2021-09-29 2024-08-13 北京干细胞与再生医学研究院 一种视网膜色素上皮细胞的扩增培养基及培养方法
KR20240150802A (ko) * 2022-02-22 2024-10-16 더 리젠츠 오브 더 유니버시티 오브 미시간 인공 세르톨리 세포 및 이의 제조 방법
CA3247810A1 (en) * 2022-04-08 2023-10-12 New York Stem Cell Foundation, Inc. IPSCS PRODUCTION PROCESSES

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG49267A1 (en) 1989-08-14 1998-05-18 Photogenesis Inc Surgical instrument and cell isolation and transplantation
US6045791A (en) 1992-03-06 2000-04-04 Photogenesis, Inc. Retinal pigment epithelium transplantation
US6416998B1 (en) 1992-09-02 2002-07-09 Baylor College Of Medicine Plasmid encoding a modified steroid hormone
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5763270A (en) 1995-06-07 1998-06-09 Genemedicine, Inc. Plasmid for delivery of nucleic acids to cells and methods of use
US6117985A (en) * 1995-06-16 2000-09-12 Stemcell Technologies Inc. Antibody compositions for preparing enriched cell preparations
CA2277278A1 (en) 1997-01-10 1998-07-16 Life Technologies, Inc. Embryonic stem cell serum replacement
JP5943533B2 (ja) 2000-05-17 2016-07-06 アステリアス バイオセラピューティクス インコーポレイテッド 神経前駆細胞の集団
US20030211603A1 (en) 2001-08-14 2003-11-13 Earp David J. Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells
WO2004028563A1 (en) 2002-09-27 2004-04-08 Genexine Inc. A vaccine enhancing the protective immunity to hepatitis c virus using plasmid dna and recombinant adenovirus
US7682828B2 (en) 2003-11-26 2010-03-23 Whitehead Institute For Biomedical Research Methods for reprogramming somatic cells
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
BRPI0507074A (pt) 2004-01-23 2007-06-19 Advanced Cell Tech Inc modalidades aperfeiçoadas para o tratamento de doenças degenerativas da retina
WO2005113754A1 (en) * 2004-05-20 2005-12-01 New York Medical College Pluripotent adult stem cells
US20080299095A1 (en) 2004-07-09 2008-12-04 Bc Cancer Agency Nup98-Hox Fusions for Expansion of Hemopoietic Stem Cells
AU2005282414C1 (en) 2004-09-08 2011-04-07 Wisconsin Alumni Research Foundation Culturing human embryonic stem cells
EP3147296A1 (en) 2005-11-14 2017-03-29 Merial, Inc. Gene therapy for renal failure
BRPI0619794B8 (pt) 2005-12-13 2022-06-14 Univ Kyoto Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas
US8129187B2 (en) 2005-12-13 2012-03-06 Kyoto University Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
JP5441099B2 (ja) * 2007-01-18 2014-03-12 独立行政法人理化学研究所 視細胞への分化誘導方法
DK3399025T3 (da) 2007-03-23 2025-06-16 Wisconsin Alumni Res Found Omprogrammering af somatiske celler
IL292561A (en) * 2007-10-12 2022-06-01 Astellas Inst For Regenerative Medicine Improved methods of rpe cell production and rpe cell preparations
US9683232B2 (en) 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
US8682810B2 (en) 2008-02-08 2014-03-25 Health Discovery Corporation Method and system for analysis of flow cytometry data using support vector machines
EP3279314A1 (en) 2008-06-04 2018-02-07 Cellular Dynamics International, Inc. Methods for the production of ips cells using non-viral approach
US20100184033A1 (en) * 2008-07-16 2010-07-22 West Michael D Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby
CA2741090C (en) 2008-10-24 2018-10-16 Wisconsin Alumni Research Foundation Pluripotent stem cells obtained by non-viral reprogramming
US20120207744A1 (en) * 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
DK2438160T3 (en) 2009-06-05 2016-01-11 Cellular Dynamics Int Inc Reprogramming of T cells and hematopoietic cells
CN102803472B (zh) 2009-06-25 2014-04-23 吉隆公司 去除了外来表型的由多能干细胞分化的子代细胞
KR101774206B1 (ko) 2009-08-07 2017-09-04 고쿠리츠 다이가쿠 호진 교토 다이가쿠 유도된 다능성 줄기 세포의 효율적인 확립 방법
WO2011028524A1 (en) * 2009-08-24 2011-03-10 Wisconsin Alumni Research Foundation Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same
US10485829B2 (en) 2009-11-17 2019-11-26 Astellas Institute For Regenerative Medicine Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells
US9005967B2 (en) 2010-01-22 2015-04-14 Kyoto University Myc variants improve induced pluripotent stem cell generation efficiency
US8278620B2 (en) 2010-05-03 2012-10-02 Thermo Finnigan Llc Methods for calibration of usable fragmentation energy in mass spectrometry
EP3399026B1 (en) 2010-06-14 2024-06-26 The Scripps Research Institute Reprogramming of cells to a new fate
JP5984217B2 (ja) 2010-06-15 2016-09-06 セルラー ダイナミクス インターナショナル， インコーポレイテッド 少量の末梢血からの人工多能性幹細胞の作製
WO2012087965A2 (en) * 2010-12-22 2012-06-28 Fate Therapauetics, Inc. Cell culture platform for single cell sorting and enhanced reprogramming of ipscs
WO2012109208A2 (en) 2011-02-08 2012-08-16 Cellular Dynamics International, Inc. Hematopoietic precursor cell production by programming
WO2012149484A2 (en) 2011-04-29 2012-11-01 University Of Southern California Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate
WO2013039792A1 (en) 2011-09-12 2013-03-21 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Immunogens based on an hiv-1 gp120 v1v2 epitope
TWI719277B (zh) * 2011-11-14 2021-02-21 美商安斯泰來再生醫藥協會 人類rpe細胞之醫藥組合物及其用途
US20130157368A1 (en) * 2011-12-20 2013-06-20 Advanced Technologies And Regenerative Medicine, Llc Induced pluripotent stem cells prepared from human kidney-derived cells
AU2013216382B2 (en) * 2012-01-31 2018-08-02 Hadasit Medical Research Services And Development Ltd. Methods of selecting retinal pigmented epithelial cells
US9850463B2 (en) * 2012-02-01 2017-12-26 The Regents Of The University Of California Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation
CN108588025A (zh) * 2012-02-17 2018-09-28 斯格本斯眼科研究所 人视网膜祖细胞的表型谱
US10519422B2 (en) 2012-02-29 2019-12-31 Riken Method of producing human retinal pigment epithelial cells
US9458428B2 (en) * 2012-06-05 2016-10-04 The Regents Of The University Of California Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells
EP2951290B1 (en) 2013-02-01 2017-11-29 The United States of America, as represented by The Secretary, Department of Health and Human Services Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
EP2970881A4 (en) 2013-03-14 2017-01-25 Children's Medical Center Corporation Compositions and methods for reprogramming hematopoietic stem cell lineages
CN105377273A (zh) * 2013-05-22 2016-03-02 耶达研究与发展公司 用于治疗眼睛疾病或病症的人类单核细胞亚群
EP3047017B1 (en) 2013-10-09 2025-09-10 The Regents of the University of California Methods of mammalian retinal stem cell production and applications
CN120384050A (zh) 2013-11-11 2025-07-29 住友化学株式会社 用于制备视网膜色素上皮细胞的方法
US20150159134A1 (en) * 2013-12-11 2015-06-11 Pfizer Limited Method for producing retinal pigment epithelial cells
CA2933083A1 (en) * 2013-12-11 2015-06-18 Pfizer Limited Method for producing retinal pigment epithelial cells
CN114807035B (zh) 2015-09-08 2024-02-02 (由卫生与公众服务部部长代表的)美利坚合众国 临床级别视网膜色素上皮细胞的可再现的分化方法
KR102675213B1 (ko) 2015-09-08 2024-06-13 스미토모 파마 가부시키가이샤 망막 색소 표피 세포의 제조 방법
KR20260003355A (ko) 2015-09-08 2026-01-06 후지필름 셀룰러 다이내믹스, 인코포레이티드 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제
CN108431211B (zh) 2015-10-20 2026-03-24 富士胶片细胞动力公司 通过遗传编程的多谱系造血前体细胞产生

Similar Documents

Publication Publication Date Title
JP2023162277A5 (https=)
CN107012117B (zh) 可从机体组织分离的多能干细胞
EP3702459B1 (en) Method for improving fetal hemoglobin expression
KR102388643B1 (ko) 혈액을 유도 만능 줄기세포로 리프로그래밍하기 위한 신규하고 효율적인 방법
JP2021118728A5 (https=)
JP7146211B2 (ja) 人工多能性幹細胞の作製方法
CN114891726B (zh) 一种人类全能样干细胞诱导培养基及其应用
JP2020503892A (ja) 三次元ｉｎ ｖｉｔｒｏ肺胞モデル、該モデルの作製方法、並びに、吸入可能製品の感作作用を測定及び／又は予測するためのその使用
WO2021202898A1 (en) Methods of making pluripotent stem cells and uses thereof
Bongiorno et al. Biophysical subsets of embryonic stem cells display distinct phenotypic and morphological signatures
WO2016010155A1 (ja) 抗原特異的ｔ細胞受容体遺伝子を有する多能性幹細胞の製造方法
JP7097050B2 (ja) 効率的な人工多能性幹細胞の樹立方法
WO2023069979A1 (en) Isolated glial progenitor cells for use in the competition treatment of age-related white matter loss
JP2016520288A (ja) 効率的な人工多能性幹細胞の樹立方法
RU2013103765A (ru) ПОПУЛЯЦИЯ Tr1-КЛЕТОК ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИХ IL-13; КЛОН Tr1 ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИЙ IL-13 И IL-10; СПОСОБЫ ИДЕНТИФИКАЦИИ И ОБОГАЩЕНИЯ ПОПУЛЯЦИИ Tr1-КЛЕТОК ЧЕЛОВЕКА; ОБОГАЩЕННАЯ ПОПУЛЯЦИЯ Tr1-КЛЕТОК ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИХ IL-13; НАБОР ДЛЯ ИДЕНТИФИКАЦИИ ПОПУЛЯЦИЯ Tr1-КЛЕТОК ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИХ IL-13; ПОПУЛЯЦИЯ Tr1-КЛЕТОК ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИХ IL-13, ДЛЯ ПРОФИЛАКТИКИ И/ИЛИ ЛЕЧЕНИЯ ИММУННОГО ОТВЕТА; СПОСОБ ИСТОЩЕНИЯ ПОПУЛЯЦИИ Tr1-КЛЕТОК ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИХ IL-13; ИСТОЩЕННАЯ ПОПУЛЯЦИЯ Tr1-КЛЕТОК ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИХ IL-13; ИСТОЩЕННАЯ ПОПУЛЯЦИЯ Tr1-КЛЕТОК ЧЕЛОВЕКА, ПРОДУЦИРУЮЩИХ IL-13, ДЛЯ УСИЛЕНИЯ ИММУННОГО ОТВЕТА
JP6563145B2 (ja) 不死化汗腺筋上皮細胞
JP7068405B2 (ja) 神経系細胞の作製方法
WO2021149822A1 (ja) 人工多能性幹細胞の作製方法
CN114438036B (zh) 一种促进干细胞向红系细胞定向分化与成熟的方法与应用
CN111334477A (zh) 阿尔茨海默病大脑皮质类器官及其获得方法、应用
CN110079526B (zh) sgRNA序列及利用CRISPR-Cas9技术制备RH阴性红细胞的方法
CN107541484A (zh) 二倍体红鲫尾鳍细胞系2nFC及其构建方法和应用
CN115820641A (zh) 一种新型miRNA抑制物及其在体外缓解iMSC衰老中的应用
JP2022104813A (ja) リプログラミング因子を導入された細胞の培養方法
Pavlović et al. Animal and plant stem cells