JP2023144018A5 - - Google Patents
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- JP2023144018A5 JP2023144018A5 JP2023129665A JP2023129665A JP2023144018A5 JP 2023144018 A5 JP2023144018 A5 JP 2023144018A5 JP 2023129665 A JP2023129665 A JP 2023129665A JP 2023129665 A JP2023129665 A JP 2023129665A JP 2023144018 A5 JP2023144018 A5 JP 2023144018A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acids
- modified
- substituted
- region
- costimulatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562241021P | 2015-10-13 | 2015-10-13 | |
| US62/241,021 | 2015-10-13 | ||
| PCT/US2016/056901 WO2017066481A1 (en) | 2015-10-13 | 2016-10-13 | Chimeric antigen receptors containing a chlorotoxin domain |
| JP2018519030A JP7085990B2 (ja) | 2015-10-13 | 2016-10-13 | クロロトキシンドメインを含むキメラ抗原レセプター |
| JP2022007016A JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022007016A Division JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023144018A JP2023144018A (ja) | 2023-10-06 |
| JP2023144018A5 true JP2023144018A5 (enExample) | 2024-02-21 |
| JP7674425B2 JP7674425B2 (ja) | 2025-05-09 |
Family
ID=57233854
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519030A Active JP7085990B2 (ja) | 2015-10-13 | 2016-10-13 | クロロトキシンドメインを含むキメラ抗原レセプター |
| JP2022007016A Active JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
| JP2023129665A Active JP7674425B2 (ja) | 2015-10-13 | 2023-08-09 | クロロトキシン領域を含むキメラ抗原受容体 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519030A Active JP7085990B2 (ja) | 2015-10-13 | 2016-10-13 | クロロトキシンドメインを含むキメラ抗原レセプター |
| JP2022007016A Active JP7331162B2 (ja) | 2015-10-13 | 2022-01-20 | クロロトキシン領域を含むキメラ抗原受容体 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11230577B2 (enExample) |
| EP (2) | EP3985027A1 (enExample) |
| JP (3) | JP7085990B2 (enExample) |
| KR (1) | KR20180056780A (enExample) |
| CN (1) | CN108368159A (enExample) |
| CA (1) | CA3001833A1 (enExample) |
| DK (1) | DK3362470T3 (enExample) |
| ES (1) | ES2902987T3 (enExample) |
| IL (2) | IL302560B2 (enExample) |
| PL (1) | PL3362470T3 (enExample) |
| PT (1) | PT3362470T (enExample) |
| WO (1) | WO2017066481A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL287889B2 (en) | 2016-02-05 | 2024-03-01 | Hope City | Administration of engineered t cells for treatment of cancers in the central nervous system |
| AU2017355504C1 (en) | 2016-11-04 | 2024-06-20 | 2Seventy Bio, Inc. | Anti-BCMA CAR T cell compositions |
| BR112019011277A2 (pt) | 2016-12-02 | 2019-10-22 | University Of Southern California | polinucleotídeo, sistema de expressão recombinante, vetor, polipeptídeo, célula recombinante, polipeptídeo de receptor imune sintético isolado ou heterodímero de polipeptídeo, célula efetora imune ou célula-tronco, população de células imunes ou efetoras, métodos de fabricação de uma célula efetora imune que expressa sir, de geração de uma população de células modificadas por rna, de fornecimento de imunidade antidoença e de tratamento ou prevenção de uma doença, composição, uso ou método, kit, e, sequência de aminoácidos. |
| CN110352197B (zh) * | 2016-12-09 | 2024-02-02 | Uab研究基金会 | 嵌合氯毒素受体 |
| WO2019084018A1 (en) * | 2017-10-23 | 2019-05-02 | City Of Hope | CAR FOR THE TREATMENT OF HIV INFECTION |
| JP2020103675A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020103677A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020108444A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020108446A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020103676A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020103674A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020108442A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020108441A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020108443A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| JP2020103673A (ja) * | 2018-12-28 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020108445A (ja) * | 2018-12-28 | 2020-07-16 | 株式会社三洋物産 | 遊技機 |
| US20220195060A1 (en) * | 2019-04-05 | 2022-06-23 | 2Seventy Bio, Inc. | Manufacturing anti-bcma car t cells |
| WO2020243007A1 (en) * | 2019-05-24 | 2020-12-03 | City Of Hope | Ccr4 targeted chimeric antigen receptor modified t cells for treatment of ccr4 positive malignancies |
| US20230374085A1 (en) * | 2020-03-11 | 2023-11-23 | City Of Hope | Dual-targeting chimeric antigen receptor modified t cells comprising il-13 and chlorotoxin for cancer treatment |
| EP4271702B1 (en) | 2020-12-30 | 2024-11-06 | VRG Therapeutics Zrt. | Chlorotoxin derivatives and use thereof |
| KR20230134134A (ko) * | 2021-01-20 | 2023-09-20 | 인8바이오 인코포레이티드 | 다가 클로로톡신 키메라 항원 수용체 |
| US20240366662A1 (en) | 2021-03-30 | 2024-11-07 | City Of Hope | Car t cell therapy and ifn gamma |
| US20230190799A1 (en) * | 2021-07-21 | 2023-06-22 | City Of Hope | Chimeric antigen receptor t cells targeting cea and anti-cea-il2 immunocytokines for cancer therapy |
| WO2023092733A1 (zh) * | 2021-11-25 | 2023-06-01 | 苏州慧疗生物医药科技有限公司 | 一种用于有效递送核酸的环状多肽载体及其变化形式 |
| CN114014941B (zh) * | 2022-01-10 | 2022-04-12 | 卡瑞济(北京)生命科技有限公司 | 靶向IL13Rα2的嵌合抗原受体及其用途 |
| JP2025508371A (ja) * | 2022-02-11 | 2025-03-26 | フレッド ハッチンソン キャンサー センター | Ｓｔｅａｐ１に結合するキメラ抗原受容体 |
| US20250368958A1 (en) * | 2022-06-14 | 2025-12-04 | Purdue Research Foundation | Car-expressing pluripotent stem cell-derived neutrophils loaded with drug nanoparticles and uses thereof |
| WO2025235801A1 (en) | 2024-05-08 | 2025-11-13 | City Of Hope | Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2339683T3 (es) * | 2004-04-06 | 2010-05-24 | Transmolecular, Inc. | Diagnostico y tratamiento de canceres de celulas mieloides y linfoides. |
| CN100564517C (zh) * | 2006-09-21 | 2009-12-02 | 武汉大学 | 一种蝎抗神经胶质瘤肽及其制备方法和应用 |
| WO2010025177A1 (en) * | 2008-08-26 | 2010-03-04 | City Of Hope | Method and compositions for enhanced anti-tumor effector functioning of t cells |
| EP3444333A1 (en) | 2009-10-22 | 2019-02-20 | Thomas Jefferson University | Cell-based anti-cancer compositions and methods of making and using the same |
| CN106995493B (zh) | 2010-02-04 | 2021-09-24 | 卫材公司 | 氯毒素多肽和结合物及其应用 |
| US10156559B2 (en) * | 2012-12-10 | 2018-12-18 | Fred Hutchinson Cancer Research Center | Lipocalin fusion partners |
| UY35468A (es) * | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| US10144770B2 (en) * | 2013-10-17 | 2018-12-04 | National University Of Singapore | Chimeric receptors and uses thereof in immune therapy |
| CN107074957B (zh) | 2014-01-13 | 2021-05-07 | 希望之城公司 | 在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法 |
| HK1250918A1 (zh) * | 2015-04-06 | 2019-01-18 | Cytoimmune Therapeutics, Inc. | 用於胶质母细胞瘤的egfr导向的car疗法 |
| EP3302197B1 (en) * | 2015-05-29 | 2018-11-14 | Koninklijke Philips N.V. | Blender with a sealing gasket comprising ribs |
-
2016
- 2016-10-13 ES ES16791158T patent/ES2902987T3/es active Active
- 2016-10-13 CA CA3001833A patent/CA3001833A1/en active Pending
- 2016-10-13 CN CN201680072823.2A patent/CN108368159A/zh active Pending
- 2016-10-13 PL PL16791158T patent/PL3362470T3/pl unknown
- 2016-10-13 EP EP21197997.6A patent/EP3985027A1/en active Pending
- 2016-10-13 IL IL302560A patent/IL302560B2/en unknown
- 2016-10-13 DK DK16791158.5T patent/DK3362470T3/da active
- 2016-10-13 EP EP16791158.5A patent/EP3362470B1/en active Active
- 2016-10-13 IL IL258670A patent/IL258670B2/en unknown
- 2016-10-13 WO PCT/US2016/056901 patent/WO2017066481A1/en not_active Ceased
- 2016-10-13 US US15/767,960 patent/US11230577B2/en active Active
- 2016-10-13 PT PT167911585T patent/PT3362470T/pt unknown
- 2016-10-13 JP JP2018519030A patent/JP7085990B2/ja active Active
- 2016-10-13 KR KR1020187013153A patent/KR20180056780A/ko active Pending
-
2021
- 2021-11-05 US US17/520,402 patent/US20220177528A1/en active Pending
-
2022
- 2022-01-20 JP JP2022007016A patent/JP7331162B2/ja active Active
-
2023
- 2023-08-09 JP JP2023129665A patent/JP7674425B2/ja active Active
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