JP2023052201A5 - - Google Patents
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- JP2023052201A5 JP2023052201A5 JP2023000295A JP2023000295A JP2023052201A5 JP 2023052201 A5 JP2023052201 A5 JP 2023052201A5 JP 2023000295 A JP2023000295 A JP 2023000295A JP 2023000295 A JP2023000295 A JP 2023000295A JP 2023052201 A5 JP2023052201 A5 JP 2023052201A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- compound
- alkyl
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562235896P | 2015-10-01 | 2015-10-01 | |
| US62/235,896 | 2015-10-01 | ||
| JP2018516828A JP7411326B2 (ja) | 2015-10-01 | 2016-09-30 | タンパク質－タンパク質インターフェースを分析するための方法および試薬 |
| PCT/US2016/054691 WO2017059207A1 (en) | 2015-10-01 | 2016-09-30 | Methods and reagents for analyzing protein-protein interfaces |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018516828A Division JP7411326B2 (ja) | 2015-10-01 | 2016-09-30 | タンパク質－タンパク質インターフェースを分析するための方法および試薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023052201A JP2023052201A (ja) | 2023-04-11 |
| JP2023052201A5 true JP2023052201A5 (https=) | 2023-06-14 |
| JP7812813B2 JP7812813B2 (ja) | 2026-02-10 |
Family
ID=58427956
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018516828A Active JP7411326B2 (ja) | 2015-10-01 | 2016-09-30 | タンパク質－タンパク質インターフェースを分析するための方法および試薬 |
| JP2023000295A Active JP7812813B2 (ja) | 2015-10-01 | 2023-01-04 | タンパク質－タンパク質インターフェースを分析するための方法および試薬 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018516828A Active JP7411326B2 (ja) | 2015-10-01 | 2016-09-30 | タンパク質－タンパク質インターフェースを分析するための方法および試薬 |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US9989535B2 (https=) |
| EP (2) | EP4242304A3 (https=) |
| JP (2) | JP7411326B2 (https=) |
| AU (3) | AU2016329064B2 (https=) |
| CA (1) | CA3000822A1 (https=) |
| WO (1) | WO2017059207A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9428845B1 (en) | 2010-12-28 | 2016-08-30 | Warp Drive Bio, Inc. | Identifying new therapeutic agents |
| US10533016B2 (en) | 2015-01-09 | 2020-01-14 | Revolution Medicines, Inc. | Compounds that participate in cooperative binding and uses thereof |
| WO2017059207A1 (en) | 2015-10-01 | 2017-04-06 | Warp Drive Bio, Inc. | Methods and reagents for analyzing protein-protein interfaces |
| US11066416B2 (en) | 2016-02-04 | 2021-07-20 | The Johns Hopkins University | Rapafucin derivative compounds and methods of use thereof |
| US10774110B2 (en) | 2016-02-04 | 2020-09-15 | The Johns Hopkins University | Rapadocins, inhibitors of equilibrative nucleoside transporter 1 and uses thereof |
| CA3013783A1 (en) | 2016-02-04 | 2017-08-10 | The Johns Hopkins University | Rapaglutins, novel inhibitors of glut and use thereof |
| CA3020594A1 (en) | 2016-04-12 | 2017-10-19 | Warp Drive Bio, Inc. | Compositions and methods for the production of compounds |
| KR102598895B1 (ko) | 2016-07-12 | 2023-11-07 | 레볼루션 메디슨즈, 인크. | 다른자리 입체성 shp2 억제제로서의 2,5-이치환 3-메틸 피라진 및 2,5,6-3치환 3-메틸 피라진 |
| MX2019008695A (es) | 2017-01-23 | 2019-09-11 | Revolution Medicines Inc | Compuestos biciclicos como inhibidores alostericos de shp2. |
| MX2019008696A (es) | 2017-01-23 | 2019-09-13 | Revolution Medicines Inc | Compuestos de piridina como inhibidores de shp2 alostericos. |
| KR20240093922A (ko) * | 2017-04-05 | 2024-06-24 | 레볼루션 메디슨즈, 인크. | 단백질-단백질 계면을 분석하기 위한 방법 및 시약 |
| AU2018248417A1 (en) * | 2017-04-05 | 2019-11-14 | Revolution Medicines, Inc. | Compounds that participate in cooperative binding and uses thereof |
| CA3074690A1 (en) | 2017-09-07 | 2019-03-14 | Revolution Medicines, Inc. | Shp2 inhibitor compositions and methods for treating cancer |
| MX2020003579A (es) | 2017-10-12 | 2020-07-22 | Revolution Medicines Inc | Compuestos de piridina, pirazina, y triazina como inhibidores de shp2 alostericos. |
| BR112020009757A2 (pt) | 2017-12-15 | 2020-11-03 | Revolution Medicines, Inc. | compostos policíclicos como inibidores alostéricos de shp2 |
| US11802132B2 (en) * | 2018-02-23 | 2023-10-31 | Dana-Farber Cancer Institute, Inc. | Small molecules for inducing selective protein degradation and uses thereof |
| CN120699039A (zh) | 2019-11-04 | 2025-09-26 | 锐新医药公司 | Ras抑制剂 |
| MX2022005359A (es) | 2019-11-04 | 2022-06-02 | Revolution Medicines Inc | Inhibidores de ras. |
| US20250388598A1 (en) * | 2019-11-04 | 2025-12-25 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2021091956A1 (en) | 2019-11-04 | 2021-05-14 | Revolution Medicines, Inc. | Ras inhibitors |
| EP4055365B1 (en) * | 2019-11-08 | 2026-01-21 | NanoTemper Technologies GmbH | Characterization of particles in solution |
| CN111118046B (zh) * | 2020-01-16 | 2022-02-22 | 中国人民解放军军事科学院军事医学研究院 | 一种能够调控MSCs成脂肪分化能力的基因及其衍生产品 |
| GB202007106D0 (en) * | 2020-05-14 | 2020-07-01 | Ucl Business Plc | Cyclosporine analogues |
| MX2023003060A (es) | 2020-09-15 | 2023-04-05 | Revolution Medicines Inc | Derivados indolicos como inhibidores de ras en el tratamiento del cancer. |
| AU2022268962A1 (en) | 2021-05-05 | 2023-12-14 | Revolution Medicines, Inc. | Ras inhibitors for the treatment of cancer |
| AR127308A1 (es) | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
| CN119661684B (zh) * | 2024-10-21 | 2025-11-25 | 山东大学 | 一种高抗炎活性的脂联素突变体及其制备方法与应用 |
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| ATE92501T1 (de) | 1984-10-04 | 1993-08-15 | Sandoz Ag | Monoklonale antikoerper gegen zyklosporine. |
| EP0194972B1 (en) * | 1985-03-11 | 1992-07-29 | Sandoz Ag | Novel cyclosporins |
| DK0393934T3 (da) | 1989-04-15 | 1994-11-21 | Nippon Chemiphar Co | Nye peptider samt antidemensmidler indeholdende disse peptider |
| US5137877B1 (en) * | 1990-05-14 | 1996-01-30 | Bristol Myers Squibb Co | Bifunctional linking compounds conjugates and methods for their production |
| DK0562853T3 (da) | 1992-03-27 | 1996-07-01 | American Home Prod | 29-Demethoxyrapamycin til fremkaldelse af immunsuppression |
| ES2164713T3 (es) | 1993-09-20 | 2002-03-01 | Univ Leland Stanford Junior | Produccion recombinante de nuevos poliquetidos. |
| IL112873A (en) | 1994-03-08 | 2005-03-20 | Wyeth Corp | Rapamycin-fkbp12 binding proteins, their isolation and their use |
| GB9410142D0 (en) | 1994-05-20 | 1994-07-06 | Univ Warwick | Carbapenems |
| GB9524630D0 (en) | 1994-12-24 | 1996-01-31 | Zeneca Ltd | Chemical compounds |
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| JP2012532929A (ja) * | 2009-07-13 | 2012-12-20 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 二機能性のステープリングされたポリペプチドおよびそれらの使用 |
| EP2456777A2 (en) | 2009-07-24 | 2012-05-30 | Université Henri Poincaré - Nancy 1 | Stambomycin and derivatives, their production and their use as drugs |
| US20130072439A1 (en) | 2009-09-22 | 2013-03-21 | Huw M. Nash | Peptidomimetic macrocycles |
| US20120208720A1 (en) | 2009-10-22 | 2012-08-16 | Kenji Kashiwagi | Rapid display method in translational synthesis of peptide |
| EP2646440A4 (en) | 2010-11-30 | 2014-06-18 | Univ Johns Hopkins | CYCLIC HYBRID LIBRARIES AND SCREENS FOR THIS |
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| AU2012257513B2 (en) | 2011-05-19 | 2017-05-11 | Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) | Macrocyclic compounds as protein kinase inhibitors |
| WO2012174489A2 (en) | 2011-06-15 | 2012-12-20 | The Ohio State University | Small molecule composite surfaces as inhibitors of protein-protein interactions |
| DE102011111991A1 (de) * | 2011-08-30 | 2013-02-28 | Lead Discovery Center Gmbh | Neue Cyclosporin-Derivate |
| WO2013052393A1 (en) | 2011-10-05 | 2013-04-11 | Merck Sharp & Dohme Corp. | 3-PYRIDYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS |
| AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
| PL2872157T3 (pl) | 2012-07-12 | 2020-07-13 | Hangzhou Dac Biotech Co., Ltd | Koniugaty wiążących komórkę cząsteczek ze środkami cytotoksycznymi |
| US10131682B2 (en) * | 2012-11-24 | 2018-11-20 | Hangzhou Dac Biotech Co., Ltd. | Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules |
| EP2806274A1 (en) | 2013-05-24 | 2014-11-26 | AIT Austrian Institute of Technology GmbH | Lung cancer diagnostic method and means |
| US10233431B2 (en) | 2014-02-26 | 2019-03-19 | The Regents Of The University Of California | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases |
| US20170067894A1 (en) | 2014-03-03 | 2017-03-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Method and device for detection of pseudomonas aeruginosa |
| US10533016B2 (en) | 2015-01-09 | 2020-01-14 | Revolution Medicines, Inc. | Compounds that participate in cooperative binding and uses thereof |
| TW201629069A (zh) | 2015-01-09 | 2016-08-16 | 霍普驅動生物科技股份有限公司 | 參與協同結合之化合物及其用途 |
| US10077289B2 (en) * | 2015-03-31 | 2018-09-18 | Allergan, Inc. | Cyclosporins modified on the MeBmt sidechain by heterocyclic rings |
| WO2017059207A1 (en) | 2015-10-01 | 2017-04-06 | Warp Drive Bio, Inc. | Methods and reagents for analyzing protein-protein interfaces |
| JP2020501519A (ja) | 2016-10-28 | 2020-01-23 | ギンゴー バイオワークス， インコーポレイテッド | 化合物の生産のための組成物および方法 |
-
2016
- 2016-09-30 WO PCT/US2016/054691 patent/WO2017059207A1/en not_active Ceased
- 2016-09-30 EP EP23172763.7A patent/EP4242304A3/en active Pending
- 2016-09-30 JP JP2018516828A patent/JP7411326B2/ja active Active
- 2016-09-30 CA CA3000822A patent/CA3000822A1/en active Pending
- 2016-09-30 US US15/282,430 patent/US9989535B2/en active Active
- 2016-09-30 EP EP16852685.3A patent/EP3355930A4/en not_active Withdrawn
- 2016-09-30 AU AU2016329064A patent/AU2016329064B2/en active Active
-
2018
- 2018-05-09 US US15/974,921 patent/US10948495B2/en active Active
- 2018-05-09 US US15/974,923 patent/US10466249B2/en active Active
-
2021
- 2021-01-28 US US17/161,505 patent/US20210405060A1/en not_active Abandoned
-
2023
- 2023-01-04 JP JP2023000295A patent/JP7812813B2/ja active Active
-
2024
- 2024-01-17 AU AU2024200321A patent/AU2024200321A1/en not_active Abandoned
- 2024-03-01 US US18/593,086 patent/US20250085291A1/en active Pending
-
2026
- 2026-02-20 AU AU2026201288A patent/AU2026201288A1/en active Pending
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