JP2023052051A5 - - Google Patents
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- JP2023052051A5 JP2023052051A5 JP2022206177A JP2022206177A JP2023052051A5 JP 2023052051 A5 JP2023052051 A5 JP 2023052051A5 JP 2022206177 A JP2022206177 A JP 2022206177A JP 2022206177 A JP2022206177 A JP 2022206177A JP 2023052051 A5 JP2023052051 A5 JP 2023052051A5
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- Japan
- Prior art keywords
- cell
- composition
- casl3a
- delivery system
- functional domains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000004027 cell Anatomy 0.000 claims 9
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 241001545398 Listeria weihenstephanensis Species 0.000 claims 4
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 claims 4
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 claims 4
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- 102000015619 APOBEC Deaminases Human genes 0.000 claims 2
- 108010024100 APOBEC Deaminases Proteins 0.000 claims 2
- 239000002126 C01EB10 - Adenosine Substances 0.000 claims 2
- 241000210552 Carnobacterium gallinarum DSM 4847 Species 0.000 claims 2
- 241000193403 Clostridium Species 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 229930010555 Inosine Natural products 0.000 claims 2
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 claims 2
- 241000448224 Lachnospiraceae bacterium MA2020 Species 0.000 claims 2
- 241000412895 Lachnospiraceae bacterium NK4A179 Species 0.000 claims 2
- 241000029603 Leptotrichia shahii Species 0.000 claims 2
- 241000778057 Leptotrichia wadei F0279 Species 0.000 claims 2
- 241000186807 Listeria seeligeri Species 0.000 claims 2
- 241001112727 Listeriaceae Species 0.000 claims 2
- 208000009869 Neu-Laxova syndrome Diseases 0.000 claims 2
- 108010077850 Nuclear Localization Signals Proteins 0.000 claims 2
- 241000007215 Paludibacter propionicigenes WB4 Species 0.000 claims 2
- 241000191023 Rhodobacter capsulatus Species 0.000 claims 2
- 241000730265 Rhodobacter capsulatus R121 Species 0.000 claims 2
- 241000433126 Rhodobacter capsulatus SB 1003 Species 0.000 claims 2
- 241000274840 [Clostridium] aminophilum DSM 10710 Species 0.000 claims 2
- 229960005305 adenosine Drugs 0.000 claims 2
- 229940104302 cytosine Drugs 0.000 claims 2
- 210000003527 eukaryotic cell Anatomy 0.000 claims 2
- 229960003786 inosine Drugs 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 230000009870 specific binding Effects 0.000 claims 2
- 229940035893 uracil Drugs 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 210000001808 exosome Anatomy 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000003981 vehicle Substances 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023098872A JP2023134453A (ja) | 2016-06-17 | 2023-06-16 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
| JP2025087622A JP2025138635A (ja) | 2016-06-17 | 2025-05-27 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
Applications Claiming Priority (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662351803P | 2016-06-17 | 2016-06-17 | |
| US201662351662P | 2016-06-17 | 2016-06-17 | |
| US62/351,662 | 2016-06-17 | ||
| US62/351,803 | 2016-06-17 | ||
| US201662376377P | 2016-08-17 | 2016-08-17 | |
| US62/376,377 | 2016-08-17 | ||
| US201662410366P | 2016-10-19 | 2016-10-19 | |
| US62/410,366 | 2016-10-19 | ||
| US201662432240P | 2016-12-09 | 2016-12-09 | |
| US62/432,240 | 2016-12-09 | ||
| US201762471792P | 2017-03-15 | 2017-03-15 | |
| US62/471,792 | 2017-03-15 | ||
| US201762484786P | 2017-04-12 | 2017-04-12 | |
| US62/484,786 | 2017-04-12 | ||
| JP2018566199A JP7267013B2 (ja) | 2016-06-17 | 2017-06-19 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
| PCT/US2017/038154 WO2017219027A1 (en) | 2016-06-17 | 2017-06-19 | Type vi crispr orthologs and systems |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018566199A Division JP7267013B2 (ja) | 2016-06-17 | 2017-06-19 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023098872A Division JP2023134453A (ja) | 2016-06-17 | 2023-06-16 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023052051A JP2023052051A (ja) | 2023-04-11 |
| JP2023052051A5 true JP2023052051A5 (https=) | 2023-06-27 |
Family
ID=59295312
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018566199A Active JP7267013B2 (ja) | 2016-06-17 | 2017-06-19 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
| JP2022206177A Pending JP2023052051A (ja) | 2016-06-17 | 2022-12-23 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
| JP2023098872A Pending JP2023134453A (ja) | 2016-06-17 | 2023-06-16 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
| JP2025087622A Pending JP2025138635A (ja) | 2016-06-17 | 2025-05-27 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018566199A Active JP7267013B2 (ja) | 2016-06-17 | 2017-06-19 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023098872A Pending JP2023134453A (ja) | 2016-06-17 | 2023-06-16 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
| JP2025087622A Pending JP2025138635A (ja) | 2016-06-17 | 2025-05-27 | Ｖｉ型ｃｒｉｓｐｒオルソログ及び系 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11788083B2 (https=) |
| EP (1) | EP3455357A1 (https=) |
| JP (4) | JP7267013B2 (https=) |
| KR (2) | KR20230156150A (https=) |
| CN (1) | CN109642231A (https=) |
| AU (4) | AU2017283713B2 (https=) |
| BR (1) | BR112018076190A2 (https=) |
| CA (1) | CA3028158A1 (https=) |
| WO (1) | WO2017219027A1 (https=) |
Families Citing this family (170)
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| US11435358B2 (en) | 2011-06-23 | 2022-09-06 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
| GB2510488B (en) | 2011-06-23 | 2020-04-08 | Univ Texas | Identifying peptides at the single molecule level |
| WO2016069124A1 (en) | 2014-09-15 | 2016-05-06 | Board Of Regents, The University Of Texas System | Improved single molecule peptide sequencing |
| JP6261500B2 (ja) | 2011-07-22 | 2018-01-17 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ヌクレアーゼ切断特異性の評価および改善 |
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2017
- 2017-06-19 CA CA3028158A patent/CA3028158A1/en active Pending
- 2017-06-19 JP JP2018566199A patent/JP7267013B2/ja active Active
- 2017-06-19 WO PCT/US2017/038154 patent/WO2017219027A1/en not_active Ceased
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- 2017-06-19 CN CN201780050351.5A patent/CN109642231A/zh active Pending
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- 2017-06-19 KR KR1020197001527A patent/KR20190019168A/ko not_active Ceased
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