JP2022522351A5 - - Google Patents
Info
- Publication number
- JP2022522351A5 JP2022522351A5 JP2021550182A JP2021550182A JP2022522351A5 JP 2022522351 A5 JP2022522351 A5 JP 2022522351A5 JP 2021550182 A JP2021550182 A JP 2021550182A JP 2021550182 A JP2021550182 A JP 2021550182A JP 2022522351 A5 JP2022522351 A5 JP 2022522351A5
- Authority
- JP
- Japan
- Prior art keywords
- pbmcs
- antigen
- modified
- input
- hours
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962812225P | 2019-02-28 | 2019-02-28 | |
| US62/812,225 | 2019-02-28 | ||
| EP19161964.2 | 2019-03-11 | ||
| EP19161964 | 2019-03-11 | ||
| US201962841089P | 2019-04-30 | 2019-04-30 | |
| US62/841,089 | 2019-04-30 | ||
| US201962886799P | 2019-08-14 | 2019-08-14 | |
| US62/886,799 | 2019-08-14 | ||
| US201962933304P | 2019-11-08 | 2019-11-08 | |
| US62/933,304 | 2019-11-08 | ||
| US201962948732P | 2019-12-16 | 2019-12-16 | |
| US62/948,732 | 2019-12-16 | ||
| PCT/US2020/020194 WO2020176789A1 (en) | 2019-02-28 | 2020-02-27 | Delivery of biomolecules to pbmcs to modify an immune response |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022522351A JP2022522351A (ja) | 2022-04-18 |
| JP2022522351A5 true JP2022522351A5 (enExample) | 2023-03-07 |
| JP7610773B2 JP7610773B2 (ja) | 2025-01-09 |
Family
ID=72238527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021550182A Active JP7610773B2 (ja) | 2019-02-28 | 2020-02-27 | 免疫応答を改変するためのｐｂｍｃへの生体分子の送達 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11692168B2 (enExample) |
| EP (1) | EP3931309A4 (enExample) |
| JP (1) | JP7610773B2 (enExample) |
| KR (1) | KR20210134353A (enExample) |
| CN (1) | CN114127267A (enExample) |
| AU (1) | AU2020228648A1 (enExample) |
| BR (1) | BR112021016903A2 (enExample) |
| CA (1) | CA3131701A1 (enExample) |
| CL (1) | CL2021002258A1 (enExample) |
| CO (1) | CO2021012581A2 (enExample) |
| CR (1) | CR20210493A (enExample) |
| IL (1) | IL285809A (enExample) |
| MX (1) | MX2021010320A (enExample) |
| PE (1) | PE20220379A1 (enExample) |
| PH (1) | PH12021500033A1 (enExample) |
| SG (1) | SG11202109333SA (enExample) |
| TW (1) | TWI904084B (enExample) |
| WO (1) | WO2020176789A1 (enExample) |
| ZA (1) | ZA202106308B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3344575B1 (en) | 2015-09-04 | 2020-04-15 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to cells comprising a cell wall |
| CA3023092A1 (en) | 2016-05-03 | 2017-11-09 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to induce tolerance |
| AU2019234549B2 (en) * | 2018-03-12 | 2026-02-12 | Sqz Biotechnologies Company | Methods for treating HPV-associated diseases |
| CA3131701A1 (en) * | 2019-02-28 | 2020-09-03 | Sqz Biotechnologies Company | Delivery of biomolecules to pbmcs to modify an immune response |
| KR20210149791A (ko) | 2019-04-08 | 2021-12-09 | 에스큐지 바이오테크놀로지스 컴퍼니 | 페이로드를 세포 내로 전달하기 위한 시스템에서 이용하기 위한 카트리지 |
| AU2020275413A1 (en) | 2019-05-14 | 2021-12-23 | Cedars-Sinai Medical Center | TL1A patient selection methods, systems, and devices |
| JP2023527690A (ja) * | 2020-05-11 | 2023-06-30 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | 改変ｐｂｍｃと免疫抱合体との併用療法 |
| CN116406283A (zh) * | 2020-09-02 | 2023-07-07 | Sqz生物技术公司 | 用于使用有核细胞刺激对蛋白质的hla未知免疫应答的方法 |
| US20220296691A1 (en) * | 2020-12-29 | 2022-09-22 | Sqz Biotechnologies Company | Methods for treating cancer with activating antigen carriers |
| EP4271407A1 (en) | 2020-12-29 | 2023-11-08 | SQZ Biotechnologies Company | Formulations of activating antigen carriers |
| US12150982B2 (en) * | 2020-12-29 | 2024-11-26 | Stemcell Technologies Canada Inc. | Formulations of PBMCs |
| EP4271711A1 (en) * | 2020-12-29 | 2023-11-08 | SQZ Biotechnologies Company | Methods for treating cancers with modified pbmcs |
| US20240182851A1 (en) * | 2021-04-02 | 2024-06-06 | Sqz Biotechnologies Company | Reprogramming of cells and uses thereof |
| JP2024526851A (ja) * | 2021-07-19 | 2024-07-19 | ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | モノカルボン酸トランスポーター１１の阻害によるがんの細胞治療 |
| US20250327027A1 (en) | 2021-07-29 | 2025-10-23 | Stemcell Technologies Canada Inc. | Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery |
| JP2024545582A (ja) | 2021-11-11 | 2024-12-10 | ステムセル テクノロジーズ カナダ インコーポレイテッド | マイクロ流体送達による増強された腫瘍浸潤リンパ球を作製する方法 |
| WO2024026491A2 (en) | 2022-07-28 | 2024-02-01 | Sqz Biotechnologies Company | Enhanced antigen presenting cell formulations |
| EP4561620A1 (en) | 2022-07-28 | 2025-06-04 | Stemcell Technologies Canada Inc. | Methods for treating cancer with enhanced antigen presenting cells |
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| DE2502621C3 (de) | 1975-01-23 | 1978-09-14 | Kernforschungsanlage Juelich Gmbh, 5170 Juelich | Messung elastischer und dielektrischer Eigenschaften der Membran lebender Zellen |
| US4376634A (en) | 1980-05-30 | 1983-03-15 | Mallinckrodt, Inc. | Assay kit having syringe, dilution device and reagents within sealed container |
| FR2569477B1 (fr) | 1984-08-24 | 1987-01-02 | Descartes Universite Rene | Appareil et procede pour la determination de la deformabilite des globules rouges du sang |
| JP2720161B2 (ja) | 1988-02-01 | 1998-02-25 | 株式会社アドバンス | 細胞変形能測定装置 |
| JP2685544B2 (ja) | 1988-11-11 | 1997-12-03 | 株式会社日立製作所 | 血液フィルタおよび血液検査方法並びに血液検査装置 |
| JP2532707B2 (ja) | 1990-03-08 | 1996-09-11 | 佑二 菊池 | 血液回路及びこれを用いた血液測定装置及び血液測定方法 |
| AU2002252073A1 (en) | 2001-02-22 | 2002-09-12 | The Scepens Eye Research Institute, Inc. | Tolerogenic antigen presenting cells and in treating immune-inflammatory conditions |
| ATE411054T1 (de) | 2001-08-17 | 2008-10-15 | Coley Pharm Gmbh | Kombinations-motif-immunstimulierende oligonukleotide mit verbesserter wirkung |
| WO2003020039A1 (en) | 2001-08-28 | 2003-03-13 | Rush-Presbyterian-St. Luke's Medical Center | Immune tolerance to predetermined antigens |
| US7501278B2 (en) | 2002-06-05 | 2009-03-10 | Panasonic Corporation | Extracellular potential measuring device and method for fabricating the same |
| US20060134067A1 (en) | 2003-02-18 | 2006-06-22 | Maxcyte, Inc. | Loading of cells with antigens by electroporation |
| AU2003290460A1 (en) | 2003-12-24 | 2005-07-14 | Leiden University Medical Center | Synthetic protein as tumor-specific vaccine |
| LT3173073T (lt) | 2004-05-03 | 2025-01-10 | Ipsen Biopharm Ltd. | Liposomos, skirtos vaistų pristatymui |
| WO2005123905A1 (ja) | 2004-06-17 | 2005-12-29 | Ken Nakata | 生体力学的刺激負荷による細胞培養方法及びその装置 |
| CN100591761C (zh) | 2004-08-19 | 2010-02-24 | 加的夫大学学院咨询有限公司 | 呈递抗原的人γδT细胞的制备和在免疫治疗中的用途 |
| US20060134772A1 (en) | 2004-11-18 | 2006-06-22 | The Regents Of The University Of California | System for locating cells and for cellular analysis |
| US7704743B2 (en) | 2005-03-30 | 2010-04-27 | Georgia Tech Research Corporation | Electrosonic cell manipulation device and method of use thereof |
| EP3263581B2 (en) * | 2005-05-17 | 2025-07-09 | University of Connecticut | Compositions and methods for immunomodulation in an organism |
| US9005974B2 (en) | 2005-12-09 | 2015-04-14 | Academish Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
| US8293524B2 (en) | 2006-03-31 | 2012-10-23 | Fluxion Biosciences Inc. | Methods and apparatus for the manipulation of particle suspensions and testing thereof |
| US20070249038A1 (en) | 2006-04-21 | 2007-10-25 | Andrea Adamo | Microfluidic device for single cell targeted operations |
| CA2662826A1 (en) | 2006-08-17 | 2008-02-21 | Massachusetts Institute Of Technology | Method and apparatus for microfluidic injection |
| WO2008098094A1 (en) | 2007-02-06 | 2008-08-14 | Network Biosystems, Inc. | Devices and methods for the performance of miniaturized in vitro assays |
| US20080311140A1 (en) | 2007-05-29 | 2008-12-18 | Baylor College Of Medicine | Antigen specific immunosuppression by dendritic cell therapy |
| FR2919804B1 (fr) | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
| GB0718160D0 (en) | 2007-09-18 | 2007-10-24 | Medical Res Council | Methods |
| CN101874201B (zh) | 2007-11-28 | 2012-08-15 | 柯尼卡美能达精密光学株式会社 | 血液流动性测量装置及血液流动性测量方法 |
| US20090280518A1 (en) | 2008-05-12 | 2009-11-12 | Massachusetts Institute Of Technology | System for high throughput measurement of mechanical properties of cells |
| JP5137129B2 (ja) | 2008-07-23 | 2013-02-06 | 国立大学法人山口大学 | 血液細胞の力学的特性測定装置 |
| US9115340B2 (en) | 2008-08-08 | 2015-08-25 | Agency For Science Technology & Research | Microfluidic continuous flow device |
| CA2766907A1 (en) | 2009-07-06 | 2011-01-13 | Novartis Ag | Self replicating rna molecules and uses thereof |
| US9364831B2 (en) | 2009-08-08 | 2016-06-14 | The Regents Of The University Of California | Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting |
| AU2010311515B2 (en) | 2009-10-27 | 2014-02-20 | Erytech Pharma | Composition to induce specific immune tolerance |
| MX344460B (es) | 2009-12-23 | 2016-12-14 | Cytovera Inc * | Sistema y método para la filtración de partículas. |
| US20110293558A1 (en) | 2010-03-22 | 2011-12-01 | Massachusetts Institute Of Technology | Material properties of t cells and related methods and compositions |
| DE11787873T1 (de) | 2010-11-25 | 2013-12-12 | Imnate Sarl | Immugene Peptide zur Verwendung bei der Vorbeugung und/oder Behandlung von Infektionskrankheiten, Autoimmunerkrankungen, Immunreaktionen auf Allofaktoren, allergischen Erkrankungen, Tumoren, Transplantatabstossungen und Immunreaktionen auf virale Vektoren |
| PT2768942T (pt) | 2011-10-17 | 2020-01-21 | Massachusetts Inst Technology | Entrega intracelular |
| CN104684546A (zh) | 2012-06-07 | 2015-06-03 | 哈佛大学校长及研究员协会 | 用于药物靶向的纳米疗法 |
| WO2014165707A2 (en) | 2013-04-03 | 2014-10-09 | Memorial Sloan-Kettering Cancer Center | Effective generation of tumor-targeted t-cells derived from pluripotent stem cells |
| AR095882A1 (es) | 2013-04-22 | 2015-11-18 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9 |
| KR102243597B1 (ko) | 2013-08-16 | 2021-04-26 | 메사추세츠 인스티튜트 오브 테크놀로지 | 세포로의 선택적 물질 전달 |
| KR20170074235A (ko) * | 2014-10-31 | 2017-06-29 | 메사추세츠 인스티튜트 오브 테크놀로지 | 면역 세포로의 생체분자의 전달 |
| CN107002089B (zh) | 2014-11-14 | 2021-09-07 | 麻省理工学院 | 化合物和组合物向细胞中的破坏和场实现的递送 |
| CN107250373A (zh) | 2015-01-12 | 2017-10-13 | 麻省理工学院 | 通过微流体递送实现的基因编辑 |
| AU2016289530B2 (en) | 2015-07-09 | 2021-05-06 | Massachusetts Institute Of Technology | Delivery of materials to anucleate cells |
| PL3344747T3 (pl) | 2015-09-04 | 2023-06-19 | Sqz Biotechnologies Company | Wewnątrzkomórkowe dostarczanie biocząsteczek za pośrednictwem powierzchni z porami |
| EP3344575B1 (en) | 2015-09-04 | 2020-04-15 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to cells comprising a cell wall |
| JP7019578B2 (ja) | 2015-12-30 | 2022-02-15 | セルジーン コーポレイション | Ｔリンパ球の産生方法及びそれにより産生されるｔリンパ球 |
| JP7033535B2 (ja) | 2016-01-12 | 2022-03-10 | スクイーズ バイオテクノロジーズ カンパニー | 複合体の細胞内送達 |
| CA3023092A1 (en) | 2016-05-03 | 2017-11-09 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to induce tolerance |
| AU2017259988B2 (en) | 2016-05-03 | 2023-04-27 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to induce tolerance |
| US11422127B2 (en) * | 2016-12-07 | 2022-08-23 | Albany Medical College | Ex vivo antigen and adjuvant pulsed peripheral blood mononuclear cells as a screening platform for candidate novel vaccines and candidate antigens |
| EP3720878A1 (en) | 2017-12-05 | 2020-10-14 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to modulate antibody production |
| EP3728559A1 (en) | 2017-12-20 | 2020-10-28 | SQZ Biotechnologies Company | System for delivery of a payload into a cell |
| AU2019234549B2 (en) | 2018-03-12 | 2026-02-12 | Sqz Biotechnologies Company | Methods for treating HPV-associated diseases |
| US20240374654A2 (en) | 2018-03-12 | 2024-11-14 | Stemcell Technologies Canada Inc. | Intracellular delivery of biomolecules to modify immune response |
| US20210388390A1 (en) | 2018-10-04 | 2021-12-16 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to enhance antigen presenting cell function |
| WO2020154696A1 (en) | 2019-01-25 | 2020-07-30 | Sqz Biotechnologies Company | Anucleate cell-derived vaccines |
| CA3131701A1 (en) | 2019-02-28 | 2020-09-03 | Sqz Biotechnologies Company | Delivery of biomolecules to pbmcs to modify an immune response |
| KR20210149791A (ko) | 2019-04-08 | 2021-12-09 | 에스큐지 바이오테크놀로지스 컴퍼니 | 페이로드를 세포 내로 전달하기 위한 시스템에서 이용하기 위한 카트리지 |
-
2020
- 2020-02-27 CA CA3131701A patent/CA3131701A1/en active Pending
- 2020-02-27 PH PH1/2021/500033A patent/PH12021500033A1/en unknown
- 2020-02-27 SG SG11202109333SA patent/SG11202109333SA/en unknown
- 2020-02-27 KR KR1020217030867A patent/KR20210134353A/ko active Pending
- 2020-02-27 EP EP20762663.1A patent/EP3931309A4/en active Pending
- 2020-02-27 AU AU2020228648A patent/AU2020228648A1/en active Pending
- 2020-02-27 CR CR20210493A patent/CR20210493A/es unknown
- 2020-02-27 TW TW109106460A patent/TWI904084B/zh active
- 2020-02-27 CN CN202080031336.8A patent/CN114127267A/zh active Pending
- 2020-02-27 JP JP2021550182A patent/JP7610773B2/ja active Active
- 2020-02-27 MX MX2021010320A patent/MX2021010320A/es unknown
- 2020-02-27 WO PCT/US2020/020194 patent/WO2020176789A1/en not_active Ceased
- 2020-02-27 PE PE2021001420A patent/PE20220379A1/es unknown
- 2020-02-27 US US16/803,937 patent/US11692168B2/en active Active
- 2020-02-27 BR BR112021016903A patent/BR112021016903A2/pt not_active IP Right Cessation
-
2021
- 2021-08-23 IL IL285809A patent/IL285809A/en unknown
- 2021-08-26 CL CL2021002258A patent/CL2021002258A1/es unknown
- 2021-08-30 ZA ZA2021/06308A patent/ZA202106308B/en unknown
- 2021-09-24 CO CONC2021/0012581A patent/CO2021012581A2/es unknown
-
2023
- 2023-05-17 US US18/318,842 patent/US20240228956A9/en active Pending
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