JP2021517813A5 - - Google Patents

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Publication number
JP2021517813A5
JP2021517813A5 JP2020548778A JP2020548778A JP2021517813A5 JP 2021517813 A5 JP2021517813 A5 JP 2021517813A5 JP 2020548778 A JP2020548778 A JP 2020548778A JP 2020548778 A JP2020548778 A JP 2020548778A JP 2021517813 A5 JP2021517813 A5 JP 2021517813A5
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JP
Japan
Prior art keywords
cells
modified
antigen
adjuvant
input
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JP2020548778A
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English (en)
Japanese (ja)
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JP2021517813A (ja
JP7595827B2 (ja
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Priority claimed from PCT/US2019/021705 external-priority patent/WO2019178006A2/en
Publication of JP2021517813A publication Critical patent/JP2021517813A/ja
Publication of JP2021517813A5 publication Critical patent/JP2021517813A5/ja
Priority to JP2024188260A priority Critical patent/JP2025020210A/ja
Application granted granted Critical
Publication of JP7595827B2 publication Critical patent/JP7595827B2/ja
Active legal-status Critical Current
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JP2020548778A 2018-03-12 2019-03-11 免疫応答を改変するための生体分子の細胞内送達 Active JP7595827B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024188260A JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862641987P 2018-03-12 2018-03-12
US62/641,987 2018-03-12
US201862738941P 2018-09-28 2018-09-28
US62/738,941 2018-09-28
US201962794516P 2019-01-18 2019-01-18
US62/794,516 2019-01-18
PCT/US2019/021705 WO2019178006A2 (en) 2018-03-12 2019-03-11 Intracellular delivery of biomolecules to modify immune response

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024188260A Division JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

Publications (3)

Publication Number Publication Date
JP2021517813A JP2021517813A (ja) 2021-07-29
JP2021517813A5 true JP2021517813A5 (enExample) 2022-03-18
JP7595827B2 JP7595827B2 (ja) 2024-12-09

Family

ID=66102189

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020548778A Active JP7595827B2 (ja) 2018-03-12 2019-03-11 免疫応答を改変するための生体分子の細胞内送達
JP2024188260A Pending JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

Family Applications After (1)

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JP2024188260A Pending JP2025020210A (ja) 2018-03-12 2024-10-25 免疫応答を改変するための生体分子の細胞内送達

Country Status (17)

Country Link
US (1) US20240374654A2 (enExample)
EP (1) EP3765068A2 (enExample)
JP (2) JP7595827B2 (enExample)
KR (1) KR20200130835A (enExample)
CN (1) CN112135627A (enExample)
AU (2) AU2019234550B2 (enExample)
BR (1) BR112020018612A2 (enExample)
CA (1) CA3093828A1 (enExample)
CO (1) CO2020012584A2 (enExample)
CR (1) CR20200460A (enExample)
IL (1) IL277188B2 (enExample)
MA (1) MA52010A (enExample)
MX (1) MX2020009439A (enExample)
PH (1) PH12020551436A1 (enExample)
SG (1) SG11202008864VA (enExample)
TW (1) TW202003019A (enExample)
WO (1) WO2019178006A2 (enExample)

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EP3344575B1 (en) 2015-09-04 2020-04-15 SQZ Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
CA3023092A1 (en) 2016-05-03 2017-11-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to induce tolerance
AU2019234549B2 (en) 2018-03-12 2026-02-12 Sqz Biotechnologies Company Methods for treating HPV-associated diseases
JP7340591B2 (ja) * 2018-07-11 2023-09-07 アクティム・セラピューティクス・インコーポレイテッド 遺伝子操作された免疫刺激性細菌菌株およびその使用
JP6884450B2 (ja) * 2019-02-14 2021-06-09 学校法人獨協学園獨協医科大学 T細胞ワクチン
CA3131701A1 (en) 2019-02-28 2020-09-03 Sqz Biotechnologies Company Delivery of biomolecules to pbmcs to modify an immune response
KR20210149791A (ko) 2019-04-08 2021-12-09 에스큐지 바이오테크놀로지스 컴퍼니 페이로드를 세포 내로 전달하기 위한 시스템에서 이용하기 위한 카트리지
JP2023527690A (ja) 2020-05-11 2023-06-30 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト 改変pbmcと免疫抱合体との併用療法
KR20230058388A (ko) 2020-07-29 2023-05-03 에스큐지 바이오테크놀로지스 컴퍼니 무핵 세포를 사용해 돌연변이체 ras에 대한 면역 반응을 자극하는 방법
US20250255961A1 (en) 2020-07-29 2025-08-14 Stemcell Technologies Canada Inc. Methods to stimulate immune responses to mutant ras using nucleated cells
US20220296691A1 (en) 2020-12-29 2022-09-22 Sqz Biotechnologies Company Methods for treating cancer with activating antigen carriers
EP4271407A1 (en) 2020-12-29 2023-11-08 SQZ Biotechnologies Company Formulations of activating antigen carriers
US12150982B2 (en) 2020-12-29 2024-11-26 Stemcell Technologies Canada Inc. Formulations of PBMCs
EP4271711A1 (en) 2020-12-29 2023-11-08 SQZ Biotechnologies Company Methods for treating cancers with modified pbmcs
CN115252772A (zh) * 2021-04-30 2022-11-01 华普生物技术(江苏)股份有限公司 人工合成的含CpG单链脱氧寡核苷酸在疫苗中的应用
US20250327027A1 (en) 2021-07-29 2025-10-23 Stemcell Technologies Canada Inc. Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery
JP2024545582A (ja) 2021-11-11 2024-12-10 ステムセル テクノロジーズ カナダ インコーポレイテッド マイクロ流体送達による増強された腫瘍浸潤リンパ球を作製する方法
WO2024026491A2 (en) 2022-07-28 2024-02-01 Sqz Biotechnologies Company Enhanced antigen presenting cell formulations
EP4561620A1 (en) 2022-07-28 2025-06-04 Stemcell Technologies Canada Inc. Methods for treating cancer with enhanced antigen presenting cells

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003290460A1 (en) * 2003-12-24 2005-07-14 Leiden University Medical Center Synthetic protein as tumor-specific vaccine
MX2009012922A (es) * 2007-05-31 2010-07-05 Academisch Ziekenhuis Leiden H Vacunacion intradermica de un peptido del virus del papiloma humano.
WO2009039125A1 (en) * 2007-09-17 2009-03-26 The Schepens Eye Research Institute, Inc. Use of ocular neuropeptides as immune adjuvants
CA3017298C (en) * 2009-05-15 2021-09-28 Irx Therapeutics, Inc. Compositions comprising primary cell-derived biologics for enhancing immune responses in patients
PT2768942T (pt) * 2011-10-17 2020-01-21 Massachusetts Inst Technology Entrega intracelular
US20170212116A1 (en) * 2014-01-31 2017-07-27 Ulisse Biomed Srl Biosensors for the detection of infection and associated maladies
KR20170074235A (ko) * 2014-10-31 2017-06-29 메사추세츠 인스티튜트 오브 테크놀로지 면역 세포로의 생체분자의 전달
PL3344747T3 (pl) 2015-09-04 2023-06-19 Sqz Biotechnologies Company Wewnątrzkomórkowe dostarczanie biocząsteczek za pośrednictwem powierzchni z porami
JP7033535B2 (ja) * 2016-01-12 2022-03-10 スクイーズ バイオテクノロジーズ カンパニー 複合体の細胞内送達
AU2019234549B2 (en) * 2018-03-12 2026-02-12 Sqz Biotechnologies Company Methods for treating HPV-associated diseases

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