TW202003019A - 細胞內投遞生物分子以修改免疫反應之方法 - Google Patents

細胞內投遞生物分子以修改免疫反應之方法 Download PDF

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TW202003019A
TW202003019A TW108108098A TW108108098A TW202003019A TW 202003019 A TW202003019 A TW 202003019A TW 108108098 A TW108108098 A TW 108108098A TW 108108098 A TW108108098 A TW 108108098A TW 202003019 A TW202003019 A TW 202003019A
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cell
modified
cells
antigen
adjuvant
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TW108108098A
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史考特 羅漢
李安 塔拉瑞
阿爾方索 維森特蘇雅斯
馬特 布蒂
霍華德 柏恩斯坦
卡塔琳娜 布拉格威
阿蒙 沙里
柯蘭 拉維堤
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美商Ｓｑｚ生物科技公司
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TW108108098A 2018-03-12 2019-03-11 細胞內投遞生物分子以修改免疫反應之方法 TW202003019A (zh)

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Application Number Priority Date Filing Date Title
US201862641987P 2018-03-12 2018-03-12
US62/641,987 2018-03-12
US201862738941P 2018-09-28 2018-09-28
US62/738,941 2018-09-28
US201962794516P 2019-01-18 2019-01-18
US62/794,516 2019-01-18

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TW202003019A true TW202003019A (zh) 2020-01-16

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US (1) US20240374654A2 (enExample)
EP (1) EP3765068A2 (enExample)
JP (2) JP7595827B2 (enExample)
KR (1) KR20200130835A (enExample)
CN (1) CN112135627A (enExample)
AU (2) AU2019234550B2 (enExample)
BR (1) BR112020018612A2 (enExample)
CA (1) CA3093828A1 (enExample)
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MA (1) MA52010A (enExample)
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JP7340591B2 (ja) * 2018-07-11 2023-09-07 アクティム・セラピューティクス・インコーポレイテッド 遺伝子操作された免疫刺激性細菌菌株およびその使用
JP6884450B2 (ja) * 2019-02-14 2021-06-09 学校法人獨協学園獨協医科大学 Ｔ細胞ワクチン
CA3131701A1 (en) 2019-02-28 2020-09-03 Sqz Biotechnologies Company Delivery of biomolecules to pbmcs to modify an immune response
KR20210149791A (ko) 2019-04-08 2021-12-09 에스큐지 바이오테크놀로지스 컴퍼니 페이로드를 세포 내로 전달하기 위한 시스템에서 이용하기 위한 카트리지
JP2023527690A (ja) 2020-05-11 2023-06-30 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 改変ｐｂｍｃと免疫抱合体との併用療法
KR20230058388A (ko) 2020-07-29 2023-05-03 에스큐지 바이오테크놀로지스 컴퍼니 무핵 세포를 사용해 돌연변이체 ras에 대한 면역 반응을 자극하는 방법
US20250255961A1 (en) 2020-07-29 2025-08-14 Stemcell Technologies Canada Inc. Methods to stimulate immune responses to mutant ras using nucleated cells
US20220296691A1 (en) 2020-12-29 2022-09-22 Sqz Biotechnologies Company Methods for treating cancer with activating antigen carriers
EP4271407A1 (en) 2020-12-29 2023-11-08 SQZ Biotechnologies Company Formulations of activating antigen carriers
US12150982B2 (en) 2020-12-29 2024-11-26 Stemcell Technologies Canada Inc. Formulations of PBMCs
EP4271711A1 (en) 2020-12-29 2023-11-08 SQZ Biotechnologies Company Methods for treating cancers with modified pbmcs
CN115252772A (zh) * 2021-04-30 2022-11-01 华普生物技术(江苏)股份有限公司 人工合成的含CpG单链脱氧寡核苷酸在疫苗中的应用
US20250327027A1 (en) 2021-07-29 2025-10-23 Stemcell Technologies Canada Inc. Methods to generate enhanced tumor infiltrating lymphocytes through microfluidic delivery
JP2024545582A (ja) 2021-11-11 2024-12-10 ステムセル テクノロジーズ カナダ インコーポレイテッド マイクロ流体送達による増強された腫瘍浸潤リンパ球を作製する方法
WO2024026491A2 (en) 2022-07-28 2024-02-01 Sqz Biotechnologies Company Enhanced antigen presenting cell formulations
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