JP7595827B2 - 免疫応答を改変するための生体分子の細胞内送達 - Google Patents

免疫応答を改変するための生体分子の細胞内送達 Download PDF

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JP7595827B2
JP7595827B2 JP2020548778A JP2020548778A JP7595827B2 JP 7595827 B2 JP7595827 B2 JP 7595827B2 JP 2020548778 A JP2020548778 A JP 2020548778A JP 2020548778 A JP2020548778 A JP 2020548778A JP 7595827 B2 JP7595827 B2 JP 7595827B2
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cells
modified
antigen
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adjuvant
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JP2021517813A (ja
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スコット ラフヘッド,
リーアン タラリコ,
アルフォンソ ヴィセンテ-スアレス,
マット ブーティー,
ハワード バーンスタイン,
カタリナ ブラゴヴィッチ,
アーモン アール. シャレイ,
ケラン フラヴァティ,
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ステムセル テクノロジーズ カナダ インコーポレーテッド
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JP2020548778A 2018-03-12 2019-03-11 免疫応答を改変するための生体分子の細胞内送達 Active JP7595827B2 (ja)

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US201862641987P 2018-03-12 2018-03-12
US62/641,987 2018-03-12
US201862738941P 2018-09-28 2018-09-28
US62/738,941 2018-09-28
US201962794516P 2019-01-18 2019-01-18
US62/794,516 2019-01-18
PCT/US2019/021705 WO2019178006A2 (en) 2018-03-12 2019-03-11 Intracellular delivery of biomolecules to modify immune response

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CA3023092A1 (en) 2016-05-03 2017-11-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to induce tolerance
AU2019234549B2 (en) 2018-03-12 2026-02-12 Sqz Biotechnologies Company Methods for treating HPV-associated diseases
JP7340591B2 (ja) * 2018-07-11 2023-09-07 アクティム・セラピューティクス・インコーポレイテッド 遺伝子操作された免疫刺激性細菌菌株およびその使用
JP6884450B2 (ja) * 2019-02-14 2021-06-09 学校法人獨協学園獨協医科大学 T細胞ワクチン
CA3131701A1 (en) 2019-02-28 2020-09-03 Sqz Biotechnologies Company Delivery of biomolecules to pbmcs to modify an immune response
KR20210149791A (ko) 2019-04-08 2021-12-09 에스큐지 바이오테크놀로지스 컴퍼니 페이로드를 세포 내로 전달하기 위한 시스템에서 이용하기 위한 카트리지
JP2023527690A (ja) 2020-05-11 2023-06-30 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト 改変pbmcと免疫抱合体との併用療法
KR20230058388A (ko) 2020-07-29 2023-05-03 에스큐지 바이오테크놀로지스 컴퍼니 무핵 세포를 사용해 돌연변이체 ras에 대한 면역 반응을 자극하는 방법
US20250255961A1 (en) 2020-07-29 2025-08-14 Stemcell Technologies Canada Inc. Methods to stimulate immune responses to mutant ras using nucleated cells
US20220296691A1 (en) 2020-12-29 2022-09-22 Sqz Biotechnologies Company Methods for treating cancer with activating antigen carriers
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