JP2022521746A - グルタルイミド骨格に基づく硫黄含有化合物及びその応用 - Google Patents

グルタルイミド骨格に基づく硫黄含有化合物及びその応用 Download PDF

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JP2022521746A
JP2022521746A JP2021549312A JP2021549312A JP2022521746A JP 2022521746 A JP2022521746 A JP 2022521746A JP 2021549312 A JP2021549312 A JP 2021549312A JP 2021549312 A JP2021549312 A JP 2021549312A JP 2022521746 A JP2022521746 A JP 2022521746A
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thio
piperidine
dione
oxoisoindoline
amino
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JP2022521746A5 (enExample
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小宝 楊
標 姜
星 仇
寧 孫
仁紅 孫
林義 劉
超偉 任
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ShanghaiTech University
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ShanghaiTech University
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2021549312A 2019-02-25 2020-02-25 グルタルイミド骨格に基づく硫黄含有化合物及びその応用 Pending JP2022521746A (ja)

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CN201910138460.3 2019-02-25
CN201910138460 2019-02-25
PCT/CN2020/076578 WO2020173426A1 (zh) 2019-02-25 2020-02-25 基于戊二酰亚胺骨架的含硫化合物及其应用

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JP2023525951A (ja) * 2020-02-25 2023-06-20 シャンハイテック ユニバーシティ グルタルイミド骨格に基づく化合物及びその使用
US12564638B2 (en) 2019-08-05 2026-03-03 Shanghaitech University EGFR protein degradant and anti-tumor application thereof
US12582641B2 (en) 2019-02-25 2026-03-24 Shanghaitech University Sulfur-containing compound based on glutarimide skeleton and application thereof

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CA3017740A1 (en) 2016-03-16 2017-09-21 Pearlie BURNETTE Small molecules against cereblon to enhance effector t cell function
US12226424B2 (en) 2018-04-09 2025-02-18 Shanghaitech University Target protein degradation compounds, their anti-tumor use, their intermediates and use of intermediates
EA202190248A1 (ru) 2018-07-11 2021-06-16 Х. Ли Моффитт Кэнсер Сентер Энд Рисерч Инститьют, Инк. Димерные иммуномодулирующие соединения против механизмов на основе цереблона
CN111747924B (zh) * 2019-03-29 2023-11-10 华东师范大学 一类来那度胺/泊马度胺类似物及其应用
CN114456173B (zh) * 2020-11-10 2023-09-19 江苏恒瑞医药股份有限公司 稠环基取代的环己二酰亚胺类衍生物、其制备方法及其在医药上的应用
WO2023025136A1 (zh) * 2021-08-27 2023-03-02 杭州格博生物医药有限公司 异吲哚啉酮化合物及其用途
EP4585592A1 (en) * 2022-09-08 2025-07-16 Gluetacs Therapeutics (Shanghai) Co., Ltd. Molecular glue compound based on cereblon protein design and use thereof
WO2024064358A1 (en) * 2022-09-23 2024-03-28 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
CN116284195B (zh) * 2023-02-08 2025-07-01 湖南欧亚药业有限公司 一种氟维司群的制备方法
CN117551057B (zh) * 2023-03-24 2026-04-10 浙江海正药业股份有限公司 苯并环类衍生物及其制备方法和用途
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