JP2022512672A5 - - Google Patents

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Publication number
JP2022512672A5
JP2022512672A5 JP2021519849A JP2021519849A JP2022512672A5 JP 2022512672 A5 JP2022512672 A5 JP 2022512672A5 JP 2021519849 A JP2021519849 A JP 2021519849A JP 2021519849 A JP2021519849 A JP 2021519849A JP 2022512672 A5 JP2022512672 A5 JP 2022512672A5
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JP
Japan
Prior art keywords
binding protein
antibody
use according
fused
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021519849A
Other languages
English (en)
Japanese (ja)
Other versions
JP7607556B2 (ja
JP2022512672A (ja
Filing date
Publication date
Priority claimed from EP18199879.0A external-priority patent/EP3636284A1/en
Application filed filed Critical
Publication of JP2022512672A publication Critical patent/JP2022512672A/ja
Publication of JP2022512672A5 publication Critical patent/JP2022512672A5/ja
Application granted granted Critical
Publication of JP7607556B2 publication Critical patent/JP7607556B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021519849A 2018-10-11 2019-10-11 アントラサイクリンを含む結合タンパク質-毒素融合体、および免疫腫瘍学的適用におけるその使用 Active JP7607556B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18199879.0A EP3636284A1 (en) 2018-10-11 2018-10-11 Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications
EP18199879.0 2018-10-11
PCT/EP2019/077644 WO2020074724A1 (en) 2018-10-11 2019-10-11 Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications

Publications (3)

Publication Number Publication Date
JP2022512672A JP2022512672A (ja) 2022-02-07
JP2022512672A5 true JP2022512672A5 (https=) 2022-10-21
JP7607556B2 JP7607556B2 (ja) 2024-12-27

Family

ID=63833918

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021519849A Active JP7607556B2 (ja) 2018-10-11 2019-10-11 アントラサイクリンを含む結合タンパク質-毒素融合体、および免疫腫瘍学的適用におけるその使用

Country Status (12)

Country Link
US (1) US20210379194A1 (https=)
EP (2) EP3636284A1 (https=)
JP (1) JP7607556B2 (https=)
KR (1) KR20210075085A (https=)
CN (1) CN112805037A (https=)
AU (1) AU2019358518A1 (https=)
BR (1) BR112021006269A2 (https=)
CA (1) CA3112848A1 (https=)
EA (1) EA202190653A1 (https=)
MX (1) MX2021003136A (https=)
PH (1) PH12021550750A1 (https=)
WO (1) WO2020074724A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL312204A (en) 2021-10-28 2024-06-01 Lyell Immunopharma Inc Methods for culturing cells expressing ror1-binding protein
EP4523704A1 (en) 2022-05-12 2025-03-19 Hainan Simcere Zaiming Pharmaceutical Co., Ltd. Camptothecin derivative and ligand-drug conjugate
WO2024064952A1 (en) 2022-09-23 2024-03-28 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells overexpressing c-jun
WO2024064958A1 (en) 2022-09-23 2024-03-28 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells
WO2024077174A1 (en) 2022-10-05 2024-04-11 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells
WO2025217398A1 (en) 2024-04-10 2025-10-16 Lyell Immunopharma, Inc. Methods for culturing cells with improved culture medium

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2777714A1 (en) 2013-03-15 2014-09-17 NBE-Therapeutics LLC Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme
WO2016102679A1 (en) 2014-12-23 2016-06-30 Nbe-Therapeutics Ag Binding protein drug conjugates comprising anthracycline derivatives
EP3256166A1 (en) 2015-02-09 2017-12-20 NBE Therapeutics AG Maytansine-drug conjugates of her- 2 specific binding proteins generated by site specific sortase-enzyme mediated conjugation
SG11201803098VA (en) * 2015-10-30 2018-05-30 Nbe Therapeutics Ag Anti-ror1 antibodies
US20190112385A1 (en) 2015-10-30 2019-04-18 Nbe-Therapeutics Ag Anti-mesothelin antibodies
SG11201806121PA (en) * 2016-01-20 2018-08-30 Scripps Research Inst Ror2 antibody compositions and related methods
UA125718C2 (uk) * 2016-01-20 2022-05-25 Зе Скріппс Ресеарч Інстітьют Композиції антитіл до ror1 і пов'язані з ними способи
ES3034233T3 (en) * 2016-01-22 2025-08-14 MabQuest SA Non-blocking pd1 specific antibodies
CA3035806A1 (en) * 2016-09-07 2018-03-15 University Of Canberra Lysine specific histone demethylase-1 inhibitors and uses therefor
WO2018103739A1 (zh) * 2016-12-09 2018-06-14 凯惠科技发展(上海)有限公司 抗体药物偶联物、制备方法、中间体、药物组合物及应用
EP3641831B1 (en) * 2017-06-20 2024-11-06 Sorrento Therapeutics, Inc. Cd38 antibody drug conjugate
US20210139579A1 (en) * 2017-07-20 2021-05-13 Nbe-Therapeutics Ag Multispecific antibody product that binds to different ror1 epitopes
US11447546B2 (en) 2017-07-20 2022-09-20 Nbe-Therapeutics Ag Human antibodies binding to ROR2
KR20230008269A (ko) * 2017-08-07 2023-01-13 엔비이-테라퓨틱스 아게 생체 내 내성이 높은 항체 약물 결합체
GB201721802D0 (en) * 2017-12-22 2018-02-07 Almac Discovery Ltd Ror1-specific antigen binding molecules

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