JP2022512672A5 - - Google Patents

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Publication number
JP2022512672A5
JP2022512672A5 JP2021519849A JP2021519849A JP2022512672A5 JP 2022512672 A5 JP2022512672 A5 JP 2022512672A5 JP 2021519849 A JP2021519849 A JP 2021519849A JP 2021519849 A JP2021519849 A JP 2021519849A JP 2022512672 A5 JP2022512672 A5 JP 2022512672A5
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JP
Japan
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JP2021519849A
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Japanese (ja)
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JP2022512672A (ja
JP7607556B2 (ja
JPWO2020074724A5 (https=
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JP2021519849A 2018-10-11 2019-10-11 アントラサイクリンを含む結合タンパク質-毒素融合体、および免疫腫瘍学的適用におけるその使用 Active JP7607556B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18199879.0 2018-10-11
EP18199879.0A EP3636284A1 (en) 2018-10-11 2018-10-11 Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications
PCT/EP2019/077644 WO2020074724A1 (en) 2018-10-11 2019-10-11 Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications

Publications (4)

Publication Number Publication Date
JP2022512672A JP2022512672A (ja) 2022-02-07
JP2022512672A5 true JP2022512672A5 (https=) 2022-10-21
JPWO2020074724A5 JPWO2020074724A5 (https=) 2022-10-21
JP7607556B2 JP7607556B2 (ja) 2024-12-27

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ID=63833918

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021519849A Active JP7607556B2 (ja) 2018-10-11 2019-10-11 アントラサイクリンを含む結合タンパク質-毒素融合体、および免疫腫瘍学的適用におけるその使用

Country Status (12)

Country Link
US (1) US20210379194A1 (https=)
EP (2) EP3636284A1 (https=)
JP (1) JP7607556B2 (https=)
KR (1) KR20210075085A (https=)
CN (1) CN112805037A (https=)
AU (1) AU2019358518A1 (https=)
BR (1) BR112021006269A2 (https=)
CA (1) CA3112848A1 (https=)
EA (1) EA202190653A1 (https=)
MX (1) MX2021003136A (https=)
PH (1) PH12021550750A1 (https=)
WO (1) WO2020074724A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024540099A (ja) 2021-10-28 2024-10-31 ライエル・イミュノファーマ・インコーポレイテッド Ror1結合タンパク質を発現する細胞を培養する方法
WO2023217227A1 (zh) 2022-05-12 2023-11-16 先声再明医药有限公司 喜树碱类衍生物及配体-药物偶联物
WO2024064958A1 (en) 2022-09-23 2024-03-28 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells
WO2024064952A1 (en) 2022-09-23 2024-03-28 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells overexpressing c-jun
WO2024077174A1 (en) 2022-10-05 2024-04-11 Lyell Immunopharma, Inc. Methods for culturing nr4a-deficient cells
WO2025217398A1 (en) 2024-04-10 2025-10-16 Lyell Immunopharma, Inc. Methods for culturing cells with improved culture medium

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2777714A1 (en) 2013-03-15 2014-09-17 NBE-Therapeutics LLC Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme
SG11201705041WA (en) 2014-12-23 2017-07-28 Nbe-Therapeutics Ag Binding protein drug conjugates comprising anthracycline derivatives
WO2016128410A1 (en) 2015-02-09 2016-08-18 Nbe Therapeutics Ag Maytansine-drug conjugates of her- 2 specific binding proteins generated by site specific sortase-enzyme mediated conjugation
EA201891066A1 (ru) 2015-10-30 2018-10-31 ЭнБиИ-ТЕРАПЬЮТИКС АГ Антитела к ror1
US20190112385A1 (en) 2015-10-30 2019-04-18 Nbe-Therapeutics Ag Anti-mesothelin antibodies
WO2017127702A1 (en) * 2016-01-20 2017-07-27 The Scripps Research Institute Ror2 antibody compositions and related methods
SG11201806120WA (en) * 2016-01-20 2018-08-30 Scripps Research Inst Ror1 antibody compositions and related methods
WO2017125815A2 (en) * 2016-01-22 2017-07-27 MabQuest SA Immunological reagents
CA3035806A1 (en) * 2016-09-07 2018-03-15 University Of Canberra Lysine specific histone demethylase-1 inhibitors and uses therefor
WO2018103739A1 (zh) * 2016-12-09 2018-06-14 凯惠科技发展(上海)有限公司 抗体药物偶联物、制备方法、中间体、药物组合物及应用
KR102771835B1 (ko) * 2017-06-20 2025-02-26 비바솔, 인코포레이티드. Cd38 항체 약물 접합체
WO2019016381A1 (en) * 2017-07-20 2019-01-24 Nbe-Therapeutics Ag MULTISPECIFIC ANTIBODY PRODUCT BINDING TO DIFFERENT ROR1 EPITOPES
WO2019016392A1 (en) 2017-07-20 2019-01-24 Nbe-Therapeutics Ag HUMAN ANTIBODIES BINDING TO ROR2
EP3665193A1 (en) 2017-08-07 2020-06-17 NBE Therapeutics AG Anthracycline-based antibody drug conjugates having high in vivo tolerability
GB201721802D0 (en) * 2017-12-22 2018-02-07 Almac Discovery Ltd Ror1-specific antigen binding molecules

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