JP7607556B2 - アントラサイクリンを含む結合タンパク質－毒素融合体、および免疫腫瘍学的適用におけるその使用 - Google Patents
アントラサイクリンを含む結合タンパク質－毒素融合体、および免疫腫瘍学的適用におけるその使用 Download PDFInfo
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP18199879.0 | 2018-10-11 | ||
| EP18199879.0A EP3636284A1 (en) | 2018-10-11 | 2018-10-11 | Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications |
| PCT/EP2019/077644 WO2020074724A1 (en) | 2018-10-11 | 2019-10-11 | Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications |
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| JP2022512672A JP2022512672A (ja) | 2022-02-07 |
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| JPWO2020074724A5 JPWO2020074724A5 (https=) | 2022-10-21 |
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| EP (2) | EP3636284A1 (https=) |
| JP (1) | JP7607556B2 (https=) |
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| MX (1) | MX2021003136A (https=) |
| PH (1) | PH12021550750A1 (https=) |
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| WO2023217227A1 (zh) | 2022-05-12 | 2023-11-16 | 先声再明医药有限公司 | 喜树碱类衍生物及配体-药物偶联物 |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2025217398A1 (en) | 2024-04-10 | 2025-10-16 | Lyell Immunopharma, Inc. | Methods for culturing cells with improved culture medium |
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| WO2016102679A1 (en) | 2014-12-23 | 2016-06-30 | Nbe-Therapeutics Ag | Binding protein drug conjugates comprising anthracycline derivatives |
| WO2017072361A1 (en) | 2015-10-30 | 2017-05-04 | Nbe-Therapeutics Ag | Anti-ror1 antibodies |
| WO2017127664A1 (en) | 2016-01-20 | 2017-07-27 | The Scripps Research Institute | Ror1 antibody compositions and related methods |
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| WO2016128410A1 (en) | 2015-02-09 | 2016-08-18 | Nbe Therapeutics Ag | Maytansine-drug conjugates of her- 2 specific binding proteins generated by site specific sortase-enzyme mediated conjugation |
| US20190112385A1 (en) | 2015-10-30 | 2019-04-18 | Nbe-Therapeutics Ag | Anti-mesothelin antibodies |
| WO2017127702A1 (en) * | 2016-01-20 | 2017-07-27 | The Scripps Research Institute | Ror2 antibody compositions and related methods |
| WO2017125815A2 (en) * | 2016-01-22 | 2017-07-27 | MabQuest SA | Immunological reagents |
| CA3035806A1 (en) * | 2016-09-07 | 2018-03-15 | University Of Canberra | Lysine specific histone demethylase-1 inhibitors and uses therefor |
| WO2018103739A1 (zh) * | 2016-12-09 | 2018-06-14 | 凯惠科技发展(上海)有限公司 | 抗体药物偶联物、制备方法、中间体、药物组合物及应用 |
| KR102771835B1 (ko) * | 2017-06-20 | 2025-02-26 | 비바솔, 인코포레이티드. | Cd38 항체 약물 접합체 |
| WO2019016381A1 (en) * | 2017-07-20 | 2019-01-24 | Nbe-Therapeutics Ag | MULTISPECIFIC ANTIBODY PRODUCT BINDING TO DIFFERENT ROR1 EPITOPES |
| WO2019016392A1 (en) | 2017-07-20 | 2019-01-24 | Nbe-Therapeutics Ag | HUMAN ANTIBODIES BINDING TO ROR2 |
| EP3665193A1 (en) | 2017-08-07 | 2020-06-17 | NBE Therapeutics AG | Anthracycline-based antibody drug conjugates having high in vivo tolerability |
| GB201721802D0 (en) * | 2017-12-22 | 2018-02-07 | Almac Discovery Ltd | Ror1-specific antigen binding molecules |
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2019
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2021
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016102679A1 (en) | 2014-12-23 | 2016-06-30 | Nbe-Therapeutics Ag | Binding protein drug conjugates comprising anthracycline derivatives |
| WO2017072361A1 (en) | 2015-10-30 | 2017-05-04 | Nbe-Therapeutics Ag | Anti-ror1 antibodies |
| WO2017127664A1 (en) | 2016-01-20 | 2017-07-27 | The Scripps Research Institute | Ror1 antibody compositions and related methods |
Also Published As
| Publication number | Publication date |
|---|---|
| EA202190653A1 (ru) | 2021-05-26 |
| CN112805037A (zh) | 2021-05-14 |
| KR20210075085A (ko) | 2021-06-22 |
| AU2019358518A1 (en) | 2021-04-08 |
| JP2022512672A (ja) | 2022-02-07 |
| US20210379194A1 (en) | 2021-12-09 |
| PH12021550750A1 (en) | 2022-02-21 |
| CA3112848A1 (en) | 2020-04-16 |
| MX2021003136A (es) | 2021-08-19 |
| EP3863681A1 (en) | 2021-08-18 |
| BR112021006269A2 (pt) | 2021-08-10 |
| EP3636284A1 (en) | 2020-04-15 |
| WO2020074724A1 (en) | 2020-04-16 |
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