JPWO2020074724A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020074724A5 JPWO2020074724A5 JP2021519849A JP2021519849A JPWO2020074724A5 JP WO2020074724 A5 JPWO2020074724 A5 JP WO2020074724A5 JP 2021519849 A JP2021519849 A JP 2021519849A JP 2021519849 A JP2021519849 A JP 2021519849A JP WO2020074724 A5 JPWO2020074724 A5 JP WO2020074724A5
- Authority
- JP
- Japan
- Prior art keywords
- binding protein
- medicament
- antibody
- fused
- linker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18199879.0 | 2018-10-11 | ||
| EP18199879.0A EP3636284A1 (en) | 2018-10-11 | 2018-10-11 | Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications |
| PCT/EP2019/077644 WO2020074724A1 (en) | 2018-10-11 | 2019-10-11 | Binding protein-toxin conjugates comprising anthracyclines, and use thereof in immune-oncological applications |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022512672A JP2022512672A (ja) | 2022-02-07 |
| JP2022512672A5 JP2022512672A5 (https=) | 2022-10-21 |
| JPWO2020074724A5 true JPWO2020074724A5 (https=) | 2022-10-21 |
| JP7607556B2 JP7607556B2 (ja) | 2024-12-27 |
Family
ID=63833918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021519849A Active JP7607556B2 (ja) | 2018-10-11 | 2019-10-11 | アントラサイクリンを含む結合タンパク質－毒素融合体、および免疫腫瘍学的適用におけるその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210379194A1 (https=) |
| EP (2) | EP3636284A1 (https=) |
| JP (1) | JP7607556B2 (https=) |
| KR (1) | KR20210075085A (https=) |
| CN (1) | CN112805037A (https=) |
| AU (1) | AU2019358518A1 (https=) |
| BR (1) | BR112021006269A2 (https=) |
| CA (1) | CA3112848A1 (https=) |
| EA (1) | EA202190653A1 (https=) |
| MX (1) | MX2021003136A (https=) |
| PH (1) | PH12021550750A1 (https=) |
| WO (1) | WO2020074724A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024540099A (ja) | 2021-10-28 | 2024-10-31 | ライエル・イミュノファーマ・インコーポレイテッド | Ｒｏｒ１結合タンパク質を発現する細胞を培養する方法 |
| WO2023217227A1 (zh) | 2022-05-12 | 2023-11-16 | 先声再明医药有限公司 | 喜树碱类衍生物及配体-药物偶联物 |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2025217398A1 (en) | 2024-04-10 | 2025-10-16 | Lyell Immunopharma, Inc. | Methods for culturing cells with improved culture medium |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2777714A1 (en) | 2013-03-15 | 2014-09-17 | NBE-Therapeutics LLC | Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme |
| SG11201705041WA (en) | 2014-12-23 | 2017-07-28 | Nbe-Therapeutics Ag | Binding protein drug conjugates comprising anthracycline derivatives |
| WO2016128410A1 (en) | 2015-02-09 | 2016-08-18 | Nbe Therapeutics Ag | Maytansine-drug conjugates of her- 2 specific binding proteins generated by site specific sortase-enzyme mediated conjugation |
| EA201891066A1 (ru) | 2015-10-30 | 2018-10-31 | ЭнБиИ-ТЕРАПЬЮТИКС АГ | Антитела к ror1 |
| US20190112385A1 (en) | 2015-10-30 | 2019-04-18 | Nbe-Therapeutics Ag | Anti-mesothelin antibodies |
| WO2017127702A1 (en) * | 2016-01-20 | 2017-07-27 | The Scripps Research Institute | Ror2 antibody compositions and related methods |
| SG11201806120WA (en) * | 2016-01-20 | 2018-08-30 | Scripps Research Inst | Ror1 antibody compositions and related methods |
| WO2017125815A2 (en) * | 2016-01-22 | 2017-07-27 | MabQuest SA | Immunological reagents |
| CA3035806A1 (en) * | 2016-09-07 | 2018-03-15 | University Of Canberra | Lysine specific histone demethylase-1 inhibitors and uses therefor |
| WO2018103739A1 (zh) * | 2016-12-09 | 2018-06-14 | 凯惠科技发展(上海)有限公司 | 抗体药物偶联物、制备方法、中间体、药物组合物及应用 |
| KR102771835B1 (ko) * | 2017-06-20 | 2025-02-26 | 비바솔, 인코포레이티드. | Cd38 항체 약물 접합체 |
| WO2019016381A1 (en) * | 2017-07-20 | 2019-01-24 | Nbe-Therapeutics Ag | MULTISPECIFIC ANTIBODY PRODUCT BINDING TO DIFFERENT ROR1 EPITOPES |
| WO2019016392A1 (en) | 2017-07-20 | 2019-01-24 | Nbe-Therapeutics Ag | HUMAN ANTIBODIES BINDING TO ROR2 |
| EP3665193A1 (en) | 2017-08-07 | 2020-06-17 | NBE Therapeutics AG | Anthracycline-based antibody drug conjugates having high in vivo tolerability |
| GB201721802D0 (en) * | 2017-12-22 | 2018-02-07 | Almac Discovery Ltd | Ror1-specific antigen binding molecules |
-
2018
- 2018-10-11 EP EP18199879.0A patent/EP3636284A1/en not_active Withdrawn
-
2019
- 2019-10-11 MX MX2021003136A patent/MX2021003136A/es unknown
- 2019-10-11 US US17/283,924 patent/US20210379194A1/en active Pending
- 2019-10-11 CA CA3112848A patent/CA3112848A1/en active Pending
- 2019-10-11 EA EA202190653A patent/EA202190653A1/ru unknown
- 2019-10-11 CN CN201980066701.6A patent/CN112805037A/zh active Pending
- 2019-10-11 KR KR1020217010212A patent/KR20210075085A/ko not_active Ceased
- 2019-10-11 WO PCT/EP2019/077644 patent/WO2020074724A1/en not_active Ceased
- 2019-10-11 AU AU2019358518A patent/AU2019358518A1/en active Pending
- 2019-10-11 JP JP2021519849A patent/JP7607556B2/ja active Active
- 2019-10-11 EP EP19783544.0A patent/EP3863681A1/en active Pending
- 2019-10-11 BR BR112021006269-6A patent/BR112021006269A2/pt unknown
-
2021
- 2021-04-05 PH PH12021550750A patent/PH12021550750A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112646031B (zh) | 抗4-1bb纳米抗体及其用途 | |
| JP2025163055A5 (https=) | ||
| ES2773504T3 (es) | Nuevo polipéptido que tiene afinidad por PD-L1 | |
| CN112513093A (zh) | 一种新型抗体及其制备方法和应用 | |
| JP2020516240A5 (https=) | ||
| JP2003523771A5 (https=) | ||
| JP2025183307A5 (https=) | ||
| WO2022042719A1 (zh) | 抗vegf-抗pd-l1双特异性抗体、其药物组合物及用途 | |
| WO2006020258A2 (en) | Novel tetravalent bispecific antibody | |
| JP2011501656A5 (https=) | ||
| JP2010535713A5 (https=) | ||
| JP2025508118A (ja) | 新規免疫調節剤の開発および使用 | |
| FI3941946T3 (fi) | Klaudiini-6-vasta-aineita ja klaudiini-6-vasta-ainelääkekonjugaatteja | |
| WO2002085946A1 (en) | Bispecific antibodies that bind trail-r1 and trail-r2 | |
| JP2020534012A5 (https=) | ||
| JP2025038088A5 (https=) | ||
| JP2021531732A5 (https=) | ||
| CN114380910A (zh) | 靶向人b7-h3分子的人源化单克隆抗体及其应用 | |
| JP2009529915A5 (https=) | ||
| US20220289825A1 (en) | FUSION PROTEIN TARGETING PD-L1 AND TGF-ß AND USE THEREOF | |
| CN119997974A (zh) | 一种异源二聚体融合蛋白及其应用 | |
| JPWO2020074724A5 (https=) | ||
| CN117924516B (zh) | 一种提高adc药物疗效的重组蛋白及其应用 | |
| JPWO2022104236A5 (https=) | ||
| CN103417965B (zh) | 一种含有抗vegf抗体的药物组合物 |