JP2020534012A5 - - Google Patents
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- Publication number
- JP2020534012A5 JP2020534012A5 JP2020516576A JP2020516576A JP2020534012A5 JP 2020534012 A5 JP2020534012 A5 JP 2020534012A5 JP 2020516576 A JP2020516576 A JP 2020516576A JP 2020516576 A JP2020516576 A JP 2020516576A JP 2020534012 A5 JP2020534012 A5 JP 2020534012A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- variable region
- kappa light
- heavy chain
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2017102631 | 2017-09-21 | ||
| CNPCT/CN2017/102631 | 2017-09-21 | ||
| PCT/CN2018/106619 WO2019057100A1 (en) | 2017-09-21 | 2018-09-20 | NEW ANTI-CD19 ANTIBODIES |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020534012A JP2020534012A (ja) | 2020-11-26 |
| JP2020534012A5 true JP2020534012A5 (https=) | 2021-10-28 |
| JP7295098B2 JP7295098B2 (ja) | 2023-06-20 |
Family
ID=65810659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020516576A Active JP7295098B2 (ja) | 2017-09-21 | 2018-09-20 | 新規抗ｃｄ１９抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11497769B2 (https=) |
| EP (1) | EP3684820A4 (https=) |
| JP (1) | JP7295098B2 (https=) |
| KR (2) | KR20250042189A (https=) |
| CN (2) | CN109535253B (https=) |
| AU (2) | AU2018336520B2 (https=) |
| BR (1) | BR112020005402A2 (https=) |
| CA (1) | CA3074524A1 (https=) |
| IL (2) | IL273389B2 (https=) |
| MX (2) | MX2020003093A (https=) |
| SG (1) | SG11202001817PA (https=) |
| TW (3) | TWI878186B (https=) |
| WO (1) | WO2019057100A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020232691B2 (en) | 2019-03-05 | 2023-06-29 | Nkarta, Inc. | CD19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| CN110003334B (zh) * | 2019-04-12 | 2023-05-09 | 深圳普瑞金生物药业股份有限公司 | 多肽、cd19单域抗体及其制备方法、核苷酸序列及试剂盒 |
| US12544437B2 (en) | 2019-10-04 | 2026-02-10 | Ultragenyx Pharmaceutical Inc. | Methods for improved therapeutic use of recombinant AAV |
| CN111303287B (zh) * | 2019-12-05 | 2022-05-20 | 常州费洛斯药业科技有限公司 | 一种anti-CD19的全人源抗体或抗体片段及其嵌合抗原受体和应用 |
| CN110922482B (zh) * | 2019-12-25 | 2021-08-31 | 源道隆（苏州）医学科技有限公司 | 可结合cd19的多肽及其应用 |
| IL297538A (en) * | 2020-04-24 | 2022-12-01 | Millennium Pharm Inc | Anti-cd19 antibodies and uses thereof |
| CN111840571B (zh) * | 2020-08-03 | 2022-09-20 | 杭州皓阳生物技术有限公司 | 一种抗体药物偶联物及其用途 |
| WO2022266075A1 (en) | 2021-06-14 | 2022-12-22 | Caribou Biosciences, Inc. | Methods and materials for treating cancer using car constructs with an intracellular domain comprising a stap domain and a kinase domain or a stap domain and a phosphatase domain |
| EP4368640A4 (en) * | 2021-07-09 | 2025-01-22 | Hainan Simcere Zaiming Pharmaceutical Co., Ltd. | Cd19 antibody and application thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080260731A1 (en) * | 2002-03-01 | 2008-10-23 | Bernett Matthew J | Optimized antibodies that target cd19 |
| EP2216342B1 (en) * | 2003-07-31 | 2015-04-22 | Immunomedics, Inc. | Anti-CD19 antibodies |
| CN101233156B (zh) * | 2005-06-20 | 2012-06-27 | 米德列斯公司 | Cd19抗体及其用途 |
| PL2383297T3 (pl) * | 2006-08-14 | 2013-06-28 | Xencor Inc | Zoptymalizowane przeciwciała ukierunkowane na CD19 |
| KR101456728B1 (ko) * | 2006-09-08 | 2014-10-31 | 메디뮨 엘엘씨 | 인간화 항-ｃｄ19 항체, 및 이것의 종양학, 이식 및 자가면역 질환의 치료에서의 용도 |
| CL2007003622A1 (es) * | 2006-12-13 | 2009-08-07 | Medarex Inc | Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales. |
| RU2476441C2 (ru) * | 2007-10-19 | 2013-02-27 | Сиэтл Дженетикс, Инк. | Cd19-связывающие средства и их применение |
| EP2398829A2 (en) * | 2009-02-23 | 2011-12-28 | Glenmark Pharmaceuticals S.A. | Humanized antibodies that bind to cd19 and their uses |
| EP2409993A1 (en) * | 2010-07-19 | 2012-01-25 | International-Drug-Development-Biotech | Anti-CD19 antibody having ADCC function with improved glycosylation profile |
| EP2409712A1 (en) | 2010-07-19 | 2012-01-25 | International-Drug-Development-Biotech | Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile |
| EP2524929A1 (en) * | 2011-05-17 | 2012-11-21 | Sanofi | Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms |
| JPWO2014065402A1 (ja) * | 2012-10-26 | 2016-09-08 | 株式会社ペルセウスプロテオミクス | 抗ヒトｃｄ４０モノクローナル抗体及びその利用 |
| SI2900277T1 (sl) * | 2012-12-13 | 2022-05-31 | Immunomedics, Inc. | Odmerki imunokonjugatov protiteles in SN-38 za boljšo učinkovitost in zmanjšano toksičnost |
| US9758575B2 (en) * | 2015-04-06 | 2017-09-12 | Yung Shin Pharmaceutical Industrial Co. Ltd. | Antibodies which specifically bind to canine vascular endothelial growth factor and uses thereof |
| JP6918789B2 (ja) * | 2015-10-02 | 2021-08-11 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 高親和性を有する抗ヒトｃｄｃ１９抗体 |
| CN109476749A (zh) | 2016-06-30 | 2019-03-15 | 豪夫迈·罗氏有限公司 | 改良的过继性t细胞疗法 |
| WO2019237081A1 (en) * | 2018-06-07 | 2019-12-12 | Cullinan Management, Inc. | Multi-specific binding proteins and methods of use thereof |
-
2018
- 2018-09-20 TW TW113133341A patent/TWI878186B/zh active
- 2018-09-20 EP EP18858685.3A patent/EP3684820A4/en active Pending
- 2018-09-20 AU AU2018336520A patent/AU2018336520B2/en active Active
- 2018-09-20 TW TW112133526A patent/TWI910464B/zh active
- 2018-09-20 IL IL273389A patent/IL273389B2/en unknown
- 2018-09-20 US US16/649,157 patent/US11497769B2/en active Active
- 2018-09-20 IL IL317928A patent/IL317928A/en unknown
- 2018-09-20 CN CN201811100667.3A patent/CN109535253B/zh active Active
- 2018-09-20 MX MX2020003093A patent/MX2020003093A/es unknown
- 2018-09-20 KR KR1020257008083A patent/KR20250042189A/ko active Pending
- 2018-09-20 BR BR112020005402-0A patent/BR112020005402A2/pt unknown
- 2018-09-20 JP JP2020516576A patent/JP7295098B2/ja active Active
- 2018-09-20 CA CA3074524A patent/CA3074524A1/en active Pending
- 2018-09-20 TW TW107133196A patent/TWI812645B/zh active
- 2018-09-20 SG SG11202001817PA patent/SG11202001817PA/en unknown
- 2018-09-20 CN CN202211276301.8A patent/CN115819588A/zh active Pending
- 2018-09-20 KR KR1020207011014A patent/KR102782109B1/ko active Active
- 2018-09-20 WO PCT/CN2018/106619 patent/WO2019057100A1/en not_active Ceased
-
2020
- 2020-03-19 MX MX2025009320A patent/MX2025009320A/es unknown
-
2025
- 2025-04-23 AU AU2025202830A patent/AU2025202830A1/en active Pending
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