JP2021531825A5 - - Google Patents
Info
- Publication number
- JP2021531825A5 JP2021531825A5 JP2021524131A JP2021524131A JP2021531825A5 JP 2021531825 A5 JP2021531825 A5 JP 2021531825A5 JP 2021524131 A JP2021524131 A JP 2021524131A JP 2021524131 A JP2021524131 A JP 2021524131A JP 2021531825 A5 JP2021531825 A5 JP 2021531825A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- folr1
- linker
- cdr1
- cdr2
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024056137A JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862695535P | 2018-07-09 | 2018-07-09 | |
| US62/695,535 | 2018-07-09 | ||
| PCT/IB2019/000873 WO2020016661A2 (en) | 2018-07-09 | 2019-06-26 | Antibodies specific to folate receptor alpha |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024056137A Division JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021531825A JP2021531825A (ja) | 2021-11-25 |
| JP2021531825A5 true JP2021531825A5 (https=) | 2022-07-01 |
| JPWO2020016661A5 JPWO2020016661A5 (https=) | 2022-07-01 |
| JP7623939B2 JP7623939B2 (ja) | 2025-01-29 |
Family
ID=69165230
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021524131A Active JP7623939B2 (ja) | 2018-07-09 | 2019-06-26 | 葉酸受容体アルファに特異的な抗体 |
| JP2024056137A Pending JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024056137A Pending JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12378310B2 (https=) |
| EP (1) | EP3821006A4 (https=) |
| JP (2) | JP7623939B2 (https=) |
| CN (2) | CN112955548B (https=) |
| AU (1) | AU2019304174B2 (https=) |
| TW (1) | TWI865456B (https=) |
| WO (1) | WO2020016661A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021308702A1 (en) | 2020-07-17 | 2023-03-16 | Instil Bio (Uk) Limited | Receptors providing targeted costimulation for adoptive cell therapy |
| WO2022256507A1 (en) * | 2021-06-04 | 2022-12-08 | Immunogen, Inc. | Treatment of cancer in patients with soluble fr-alpha |
| EP4355340A4 (en) | 2021-06-16 | 2025-05-21 | Instil Bio, Inc. | RECEPTORS FOR TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPY |
| EP4370213A4 (en) | 2021-07-16 | 2025-06-04 | Instil Bio (Uk) Limited | Chimeric molecules for targeted costimulation for adoptive cell therapy |
| JP2025515205A (ja) * | 2022-05-10 | 2025-05-13 | ビバソル， インコーポレイテッド | 抗ｆｏｌｒ１抗体を含む抗体－薬物コンジュゲート |
| WO2025087935A1 (en) * | 2023-10-26 | 2025-05-01 | Miltenyi Biotec B.V. & Co. KG | Chimeric antigen receptor specific for folate receptor 1 |
| US12600795B2 (en) | 2023-12-26 | 2026-04-14 | Medicovestor, Inc. | Oligomeric IgG for immunotherapeutics and diagnostics |
| CN117700557B (zh) * | 2024-02-05 | 2024-04-30 | 卡秋(江苏)生物科技有限公司 | 一种特异性结合叶酸受体α的抗体或抗原结合片段 |
| WO2025195447A1 (zh) * | 2024-03-22 | 2025-09-25 | 北京桦冠生物技术有限公司 | 结合folr1蛋白的抗体、抗体药物偶联物及其用途 |
| US20260001950A1 (en) * | 2024-07-01 | 2026-01-01 | Medicovestor, Inc. | Methods of enhancing efficacy of immunoconjugates using paired human antibodies targeted at non-overlapping b-cell epitopes on the same antigen |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0905972D0 (en) * | 2009-04-06 | 2009-05-20 | Medical Res Council | Antibodies against IL-17BR |
| ES2624835T3 (es) * | 2009-08-06 | 2017-07-17 | Immunas Pharma, Inc. | Anticuerpos que se unen específicamente a los oligómeros A beta y uso de los mismos |
| CN103037900B (zh) | 2010-02-24 | 2016-04-06 | 伊缪诺金公司 | 叶酸受体1抗体与免疫缀合物以及其用途 |
| US9402865B2 (en) | 2011-01-18 | 2016-08-02 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treating cancer |
| PL2731972T3 (pl) * | 2011-07-15 | 2018-06-29 | Eisai R&D Management Co., Ltd. | Przeciwciała skierowane przeciwko receptorowi folianowemu alfa i ich zastosowania |
| JP6224619B2 (ja) * | 2012-12-07 | 2017-11-01 | 協和発酵キリン株式会社 | 抗ｆｏｌｒ１抗体 |
| US9522196B2 (en) * | 2012-12-25 | 2016-12-20 | Kagoshima University | Antibody recognizing folate receptors α and β |
| IL298044B2 (en) * | 2013-10-08 | 2024-11-01 | Immunogen Inc | Dosing regimens of anti-FOLR1 immunoconjugate |
| EP3593812A3 (en) * | 2014-03-15 | 2020-05-27 | Novartis AG | Treatment of cancer using chimeric antigen receptor |
| US20150297744A1 (en) * | 2014-03-28 | 2015-10-22 | Immunogen, Inc. | Anti-FOLR1 Immunoconjugate Dosing Regimens |
| SG11201610620UA (en) | 2014-06-20 | 2017-01-27 | Bioalliance Cv | Anti-folate receptor aplha (fra) antibody-drug conjugates and methods of using thereof |
| WO2016033331A1 (en) * | 2014-08-28 | 2016-03-03 | Bioatla, Llc | Conditionally active chimeric antigen receptors for modified t-cells |
| TW201609152A (zh) * | 2014-09-03 | 2016-03-16 | 免疫原公司 | 包含細胞結合劑及細胞毒性劑之偶聯物 |
| RS61010B1 (sr) * | 2014-11-20 | 2020-11-30 | Hoffmann La Roche | Bispecifični antigen vezujući molekuli koji aktiviraju t ćelije protiv folr1 i cd3 |
| US11161907B2 (en) * | 2015-02-02 | 2021-11-02 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| AU2016323968B2 (en) * | 2015-09-17 | 2023-07-06 | Immunogen, Inc. | Therapeutic combinations comprising anti-FOLR1 immunoconjugates |
| US10323038B2 (en) | 2015-11-20 | 2019-06-18 | Abide Therapeutics, Inc. | Pyrazole compounds and methods of making and using same |
| US20190233512A1 (en) * | 2016-10-12 | 2019-08-01 | Sutro Biopharma, Inc. | Anti-folate receptor antibodies, compositions comprising anti-folate receptor antibodies and methods of making and using anti-folate receptor antibodies |
| US10822410B2 (en) * | 2016-11-23 | 2020-11-03 | Eisai R&D Management Co., Ltd. | Anti-folate receptor alpha antibodies and uses thereof |
-
2019
- 2019-06-26 CN CN201980058510.5A patent/CN112955548B/zh active Active
- 2019-06-26 TW TW108122446A patent/TWI865456B/zh active
- 2019-06-26 CN CN202311706505.5A patent/CN117866095A/zh active Pending
- 2019-06-26 EP EP19838513.0A patent/EP3821006A4/en active Pending
- 2019-06-26 AU AU2019304174A patent/AU2019304174B2/en active Active
- 2019-06-26 WO PCT/IB2019/000873 patent/WO2020016661A2/en not_active Ceased
- 2019-06-26 JP JP2021524131A patent/JP7623939B2/ja active Active
-
2021
- 2021-01-08 US US17/144,588 patent/US12378310B2/en active Active
-
2024
- 2024-03-29 JP JP2024056137A patent/JP2024119785A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021531825A5 (https=) | ||
| US20240182542A1 (en) | Multi-Specific Molecules | |
| JP2021531826A5 (https=) | ||
| CN110799539B (zh) | 抗4-1bb抗体及其制备和使用方法 | |
| JP2013506428A5 (https=) | ||
| CN110621337A (zh) | 抗lag3人单克隆抗体及其用途 | |
| US20050142539A1 (en) | Targeted ligands | |
| JPWO2020016662A5 (https=) | ||
| JP2018532383A5 (https=) | ||
| CN108136012A (zh) | 靶向分子的抗原结合构建体 | |
| JP2019505564A5 (https=) | ||
| JP2020533004A5 (https=) | ||
| JP2019511212A5 (https=) | ||
| JP7611931B2 (ja) | ガイダンス及びナビゲーションコントロール（ｇｎｃ）抗体様タンパク質、その製造方法及び使用方法 | |
| JP2010511388A5 (https=) | ||
| JP2020534012A5 (https=) | ||
| EP2486058A1 (en) | Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same | |
| JP2025026839A5 (https=) | ||
| JP2019512207A5 (https=) | ||
| TW202233680A (zh) | 具有增加的選擇性之多靶向性雙特異性抗原結合分子 | |
| JP2021512159A5 (https=) | ||
| CN119053347A (zh) | 免疫抗原特异性il-18免疫细胞因子及其用途 | |
| JPWO2020132190A5 (https=) | ||
| JPWO2020159754A5 (https=) | ||
| JPWO2020016661A5 (https=) |