JP2021531825A5 - - Google Patents
Info
- Publication number
- JP2021531825A5 JP2021531825A5 JP2021524131A JP2021524131A JP2021531825A5 JP 2021531825 A5 JP2021531825 A5 JP 2021531825A5 JP 2021524131 A JP2021524131 A JP 2021524131A JP 2021524131 A JP2021524131 A JP 2021524131A JP 2021531825 A5 JP2021531825 A5 JP 2021531825A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- folr1
- linker
- cdr1
- cdr2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024056137A JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862695535P | 2018-07-09 | 2018-07-09 | |
| US62/695,535 | 2018-07-09 | ||
| PCT/IB2019/000873 WO2020016661A2 (en) | 2018-07-09 | 2019-06-26 | Antibodies specific to folate receptor alpha |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024056137A Division JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021531825A JP2021531825A (ja) | 2021-11-25 |
| JP2021531825A5 true JP2021531825A5 (https=) | 2022-07-01 |
| JP7623939B2 JP7623939B2 (ja) | 2025-01-29 |
Family
ID=69165230
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021524131A Active JP7623939B2 (ja) | 2018-07-09 | 2019-06-26 | 葉酸受容体アルファに特異的な抗体 |
| JP2024056137A Pending JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024056137A Pending JP2024119785A (ja) | 2018-07-09 | 2024-03-29 | 葉酸受容体アルファに特異的な抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12378310B2 (https=) |
| EP (1) | EP3821006A4 (https=) |
| JP (2) | JP7623939B2 (https=) |
| CN (2) | CN112955548B (https=) |
| AU (1) | AU2019304174B2 (https=) |
| TW (1) | TWI865456B (https=) |
| WO (1) | WO2020016661A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4182338A1 (en) | 2020-07-17 | 2023-05-24 | Instil Bio (Uk) Limited | Receptors providing targeted costimulation for adoptive cell therapy |
| EP4347661A4 (en) * | 2021-06-04 | 2025-06-18 | ImmunoGen, Inc. | TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA |
| WO2022266192A1 (en) | 2021-06-16 | 2022-12-22 | Instil Bio, Inc. | Receptors providing targeted costimulation for adoptive cell therapy |
| EP4370213A4 (en) | 2021-07-16 | 2025-06-04 | Instil Bio (Uk) Limited | Chimeric molecules for targeted costimulation for adoptive cell therapy |
| EP4522223A1 (en) * | 2022-05-10 | 2025-03-19 | Vivasor, Inc. | Antibody-drug conjugates comprising an anti-folr1 antibody |
| WO2025087935A1 (en) * | 2023-10-26 | 2025-05-01 | Miltenyi Biotec B.V. & Co. KG | Chimeric antigen receptor specific for folate receptor 1 |
| US12600795B2 (en) | 2023-12-26 | 2026-04-14 | Medicovestor, Inc. | Oligomeric IgG for immunotherapeutics and diagnostics |
| CN117700557B (zh) * | 2024-02-05 | 2024-04-30 | 卡秋(江苏)生物科技有限公司 | 一种特异性结合叶酸受体α的抗体或抗原结合片段 |
| WO2025195447A1 (zh) * | 2024-03-22 | 2025-09-25 | 北京桦冠生物技术有限公司 | 结合folr1蛋白的抗体、抗体药物偶联物及其用途 |
| US20260001950A1 (en) * | 2024-07-01 | 2026-01-01 | Medicovestor, Inc. | Methods of enhancing efficacy of immunoconjugates using paired human antibodies targeted at non-overlapping b-cell epitopes on the same antigen |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0905972D0 (en) * | 2009-04-06 | 2009-05-20 | Medical Res Council | Antibodies against IL-17BR |
| WO2011016238A1 (en) * | 2009-08-06 | 2011-02-10 | Immunas Pharma, Inc. | Antibodies that specifically bind to a beta oligomers and use thereof |
| TWI622402B (zh) * | 2010-02-24 | 2018-05-01 | 免疫遺傳股份有限公司 | 葉酸受體１抗體類和免疫共軛物類及彼等之用途 |
| KR20140004174A (ko) | 2011-01-18 | 2014-01-10 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 암 치료를 위한 조성물 및 방법 |
| SI2731972T1 (en) | 2011-07-15 | 2018-04-30 | Eisai R&D Management Co., Ltd. | Anti-folate receptor alpha antibodies and uses thereof |
| US9207238B2 (en) * | 2012-12-07 | 2015-12-08 | Kyowa Hakko Kirin Co., Ltd. | Anti-FOLR1 antibody |
| US9522196B2 (en) * | 2012-12-25 | 2016-12-20 | Kagoshima University | Antibody recognizing folate receptors α and β |
| PL3055332T3 (pl) * | 2013-10-08 | 2020-02-28 | Immunogen, Inc. | Schematy dawkowania immunokoniugatu anty-FOLR1 |
| US20170335281A1 (en) * | 2014-03-15 | 2017-11-23 | Novartis Ag | Treatment of cancer using chimeric antigen receptor |
| US20150297744A1 (en) * | 2014-03-28 | 2015-10-22 | Immunogen, Inc. | Anti-FOLR1 Immunoconjugate Dosing Regimens |
| US9950077B2 (en) | 2014-06-20 | 2018-04-24 | Bioalliance C.V. | Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof |
| DK4074735T3 (da) * | 2014-08-28 | 2025-07-14 | Bioatla Inc | Betinget aktive kimæriske antigenreceptorer til modificerede t-celler |
| KR102508023B1 (ko) * | 2014-09-03 | 2023-03-10 | 이뮤노젠 아이엔씨 | 세포-결합제 및 세포독성 약물을 포함하는 콘주게이트 |
| PT3221356T (pt) * | 2014-11-20 | 2020-10-29 | Hoffmann La Roche | Moléculas de ligação ao antigénio biespecíficas ativadoras das células t contra folr1 e cd3 |
| WO2016126608A1 (en) * | 2015-02-02 | 2016-08-11 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| CN116440279B (zh) * | 2015-09-17 | 2026-02-24 | 伊缪诺金公司 | 包含抗folr1免疫缀合物的治疗组合 |
| WO2017087863A1 (en) | 2015-11-20 | 2017-05-26 | Abide Therapeutics, Inc. | Pyrazole compounds and methods of making and using same |
| EP3526254A1 (en) * | 2016-10-12 | 2019-08-21 | Sutro Biopharma, Inc. | Anti-folate receptor antibodies, compositions comprising anti-folate receptor antibodies and methods of making and using anti-folate receptor antibodies |
| EP3544999A1 (en) * | 2016-11-23 | 2019-10-02 | Eisai R&D Management Co., Ltd. | Anti-folate receptor alpha antibodies and uses thereof |
-
2019
- 2019-06-26 CN CN201980058510.5A patent/CN112955548B/zh active Active
- 2019-06-26 CN CN202311706505.5A patent/CN117866095A/zh active Pending
- 2019-06-26 AU AU2019304174A patent/AU2019304174B2/en active Active
- 2019-06-26 EP EP19838513.0A patent/EP3821006A4/en active Pending
- 2019-06-26 JP JP2021524131A patent/JP7623939B2/ja active Active
- 2019-06-26 WO PCT/IB2019/000873 patent/WO2020016661A2/en not_active Ceased
- 2019-06-26 TW TW108122446A patent/TWI865456B/zh active
-
2021
- 2021-01-08 US US17/144,588 patent/US12378310B2/en active Active
-
2024
- 2024-03-29 JP JP2024056137A patent/JP2024119785A/ja active Pending
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