JP2022504826A5 - - Google Patents

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Publication number
JP2022504826A5
JP2022504826A5 JP2021520222A JP2021520222A JP2022504826A5 JP 2022504826 A5 JP2022504826 A5 JP 2022504826A5 JP 2021520222 A JP2021520222 A JP 2021520222A JP 2021520222 A JP2021520222 A JP 2021520222A JP 2022504826 A5 JP2022504826 A5 JP 2022504826A5
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JP
Japan
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sequence
chain variable
variable domain
heavy chain
light chain
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JP2021520222A
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English (en)
Japanese (ja)
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JP2022504826A (ja
JP7596263B2 (ja
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Priority claimed from PCT/CA2019/051448 external-priority patent/WO2020073131A1/en
Publication of JP2022504826A publication Critical patent/JP2022504826A/ja
Publication of JP2022504826A5 publication Critical patent/JP2022504826A5/ja
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JP2021520222A 2018-10-10 2019-10-10 4-1bb及び腫瘍関連抗原に結合する抗体構築物ならびにその使用 Active JP7596263B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862744059P 2018-10-10 2018-10-10
US62/744,059 2018-10-10
PCT/CA2019/051448 WO2020073131A1 (en) 2018-10-10 2019-10-10 Antibody constructs binding 4-1bb and tumor-associated antigens and uses thereof

Publications (3)

Publication Number Publication Date
JP2022504826A JP2022504826A (ja) 2022-01-13
JP2022504826A5 true JP2022504826A5 (https=) 2022-10-18
JP7596263B2 JP7596263B2 (ja) 2024-12-09

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ID=70164178

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021520222A Active JP7596263B2 (ja) 2018-10-10 2019-10-10 4-1bb及び腫瘍関連抗原に結合する抗体構築物ならびにその使用

Country Status (10)

Country Link
US (1) US20230052369A1 (https=)
EP (1) EP3864051A4 (https=)
JP (1) JP7596263B2 (https=)
KR (1) KR20210076918A (https=)
CN (2) CN121758617A (https=)
AU (1) AU2019356806B2 (https=)
BR (1) BR112021006784A2 (https=)
CA (1) CA3113539A1 (https=)
MX (1) MX2021004058A (https=)
WO (1) WO2020073131A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230265202A1 (en) * 2020-04-15 2023-08-24 Zymeworks Inc. Antibody constructs binding 4-1bb and folate receptor alpha and uses thereof
JP7512394B2 (ja) * 2020-05-06 2024-07-08 ドラゴンフライ セラピューティクス, インコーポレイテッド Nkg2d、cd16及びclec12aに結合するタンパク質
CN112794911B (zh) * 2021-04-14 2021-08-03 上海偌妥生物科技有限公司 人源化抗叶酸受体1抗体及其应用
AU2022260298A1 (en) * 2021-04-23 2023-11-02 Shanghai Henlius Biotech, Inc. Anti-gpc3 antibodies, multispecific antibodies and methods of use
CN116769041A (zh) * 2022-03-10 2023-09-19 合肥瀚科迈博生物技术有限公司 靶向msln和4-1bb的双特异性抗体及其应用
WO2024051752A1 (en) * 2022-09-06 2024-03-14 I-Mab Biopharma Co., Ltd. Multispecific constructs and uses thereof
JP2025536308A (ja) * 2022-10-18 2025-11-05 テューブリス ゲーエムベーハー 新規なNaPi2b抗体を有する新規な抗体-薬物コンジュゲート、治療的方法、ならびにそれらの使用
WO2025131027A1 (en) * 2023-12-21 2025-06-26 Lanova Medicines Development Co., Ltd. Anti-slc34a2/anti-4-1bb antibodies and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140004174A (ko) * 2011-01-18 2014-01-10 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 암 치료를 위한 조성물 및 방법
US20170335281A1 (en) * 2014-03-15 2017-11-23 Novartis Ag Treatment of cancer using chimeric antigen receptor
EP3445788B1 (en) * 2016-04-22 2022-01-19 Alligator Bioscience AB Novel bispecific polypeptides against cd137
CN110177805B (zh) * 2016-10-19 2024-04-02 英温拉公司 抗体构建体
AU2018224094B2 (en) * 2017-02-24 2025-04-17 Macrogenics, Inc. Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof

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