JP2018537421A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018537421A5 JP2018537421A5 JP2018520394A JP2018520394A JP2018537421A5 JP 2018537421 A5 JP2018537421 A5 JP 2018537421A5 JP 2018520394 A JP2018520394 A JP 2018520394A JP 2018520394 A JP2018520394 A JP 2018520394A JP 2018537421 A5 JP2018537421 A5 JP 2018537421A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cdr3
- cdr1
- cdr2
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562245188P | 2015-10-22 | 2015-10-22 | |
| US62/245,188 | 2015-10-22 | ||
| US201662276352P | 2016-01-08 | 2016-01-08 | |
| US62/276,352 | 2016-01-08 | ||
| PCT/EP2016/075558 WO2017068186A1 (en) | 2015-10-22 | 2016-10-24 | Gitr agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018537421A JP2018537421A (ja) | 2018-12-20 |
| JP2018537421A5 true JP2018537421A5 (https=) | 2019-11-07 |
| JP7084870B2 JP7084870B2 (ja) | 2022-06-15 |
Family
ID=57211500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520394A Active JP7084870B2 (ja) | 2015-10-22 | 2016-10-24 | Ｇｉｔｒアゴニスト |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11059899B1 (https=) |
| EP (1) | EP3365371B1 (https=) |
| JP (1) | JP7084870B2 (https=) |
| CN (1) | CN108473579B (https=) |
| AU (1) | AU2016341403B2 (https=) |
| CA (1) | CA3002711A1 (https=) |
| ES (1) | ES3057922T3 (https=) |
| WO (1) | WO2017068186A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2018000948A (es) * | 2015-07-23 | 2018-09-27 | Inhibrx Inc | Proteinas de fusion que se unen a gitir multivalentes y multiespecificas. |
| EP3365371B1 (en) | 2015-10-22 | 2025-10-08 | Ablynx NV | Gitr agonists |
| EP3464360B1 (en) | 2016-05-27 | 2025-11-12 | Agenus Inc. | Anti-tim-3 antibodies and methods of use thereof |
| JP2019519536A (ja) | 2016-07-01 | 2019-07-11 | ファイブ プライム セラピューティクス， インコーポレイテッド | Ｇｉｔｒアゴニストおよびｃｐｇを用いた組み合わせ抗腫瘍療法 |
| JP7066696B2 (ja) | 2016-10-11 | 2022-05-13 | アジェナス インコーポレイテッド | 抗ｌａｇ－３抗体及びその使用方法 |
| CN110869392A (zh) | 2017-05-16 | 2020-03-06 | 百时美施贵宝公司 | 用抗gitr激动性抗体治疗癌症 |
| WO2019001559A1 (zh) | 2017-06-30 | 2019-01-03 | 江苏恒瑞医药股份有限公司 | 抗gitr抗体、其抗原结合片段及其医药用途 |
| CN110357958A (zh) * | 2018-03-26 | 2019-10-22 | 信达生物制药(苏州)有限公司 | 抗糖皮质激素诱导的肿瘤坏死因子受体(gitr)的小型化抗体、其聚合物及应用 |
| CN108640993B (zh) * | 2018-06-06 | 2020-09-04 | 暨南大学 | 一种抗重组人碱性成纤维细胞生长因子纳米抗体及其应用 |
| EP3827019A1 (en) | 2018-07-24 | 2021-06-02 | Inhibrx, Inc. | Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same |
| RU2734432C1 (ru) | 2019-04-23 | 2020-10-16 | Закрытое Акционерное Общество "Биокад" | Моноклональное антитело, которое специфически связывается с GITR |
| IL293561A (en) | 2019-12-06 | 2022-08-01 | Ablynx Nv | Polypeptides comprising immunoglobulin with one variable domain targeting TNFa and IL-23 |
| AU2021350156A1 (en) * | 2020-09-25 | 2023-06-08 | Ablynx Nv | Polypeptides comprising immunoglobulin single variable domains targeting il-13 and ox40l |
| EP4263602A1 (en) * | 2020-12-18 | 2023-10-25 | Ablynx N.V. | Polypeptides comprising immunoglobulin single variable domains targeting il-6 and tnf-alpha |
| CN112851811B (zh) * | 2021-01-28 | 2022-08-09 | 姜国胜 | 一种cd44v6纳米抗体及其作为白血病研究试剂的应用 |
| EP4339209A4 (en) * | 2021-05-10 | 2025-05-28 | MediMabbio Inc. | ANTI-GITR ANTIBODIES AND THEIR USES |
| WO2023213764A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf |
| WO2023213763A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab |
| AU2023300419A1 (en) | 2022-07-01 | 2025-01-02 | Transgene | Fusion protein comprising a surfactant-protein-d and a member of the tnfsf |
| AR131494A1 (es) | 2022-12-23 | 2025-03-26 | Ablynx Nv | Vehículos de conjugación a base de proteína |
| TW202448926A (zh) | 2023-02-17 | 2024-12-16 | 比利時商艾伯霖克斯公司 | 結合新生兒fc受體之多肽 |
| US20250270274A1 (en) * | 2024-02-26 | 2025-08-28 | Serpentide Inc. | Super long-lasting glp1 or glp1/gip analogue drug for type-2 diabetes and obesity |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1809589A (zh) * | 2003-05-23 | 2006-07-26 | Wyeth公司 | Gitr配体和gitr配体相关分子和抗体及其应用 |
| CN101218257A (zh) * | 2005-03-25 | 2008-07-09 | 托勒克斯股份有限公司 | Gitr结合分子及其用途 |
| PT2343320T (pt) * | 2005-03-25 | 2018-01-23 | Gitr Inc | Anticorpos anti-gitr e as suas utilizações |
| KR101790802B1 (ko) | 2009-09-03 | 2017-10-27 | 머크 샤프 앤드 돔 코포레이션 | 항-ｇｉｔｒ 항체 |
| TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
| SI3148579T1 (sl) * | 2014-05-28 | 2021-07-30 | Agenus Inc. | Proti GITR antitelesa in postopki z njihovo uporabo |
| PE20170441A1 (es) | 2014-06-06 | 2017-04-26 | Bristol Myers Squibb Co | Anticuerpos contra el receptor del factor de necrosis tumoral inducido por glucocorticoides (gitr) y sus usos |
| MX2017015260A (es) * | 2015-06-03 | 2018-02-19 | Squibb Bristol Myers Co | Anticuerpos anti receptor de factor de necrosis tumoral inducible por glucocorticoide (gitr) para diagnostico del cancer. |
| MX2018000948A (es) | 2015-07-23 | 2018-09-27 | Inhibrx Inc | Proteinas de fusion que se unen a gitir multivalentes y multiespecificas. |
| EP3365371B1 (en) | 2015-10-22 | 2025-10-08 | Ablynx NV | Gitr agonists |
-
2016
- 2016-10-24 EP EP16788484.0A patent/EP3365371B1/en active Active
- 2016-10-24 ES ES16788484T patent/ES3057922T3/es active Active
- 2016-10-24 AU AU2016341403A patent/AU2016341403B2/en active Active
- 2016-10-24 CA CA3002711A patent/CA3002711A1/en active Pending
- 2016-10-24 US US15/769,205 patent/US11059899B1/en active Active
- 2016-10-24 CN CN201680075294.1A patent/CN108473579B/zh active Active
- 2016-10-24 JP JP2018520394A patent/JP7084870B2/ja active Active
- 2016-10-24 WO PCT/EP2016/075558 patent/WO2017068186A1/en not_active Ceased
-
2021
- 2021-05-14 US US17/320,395 patent/US11919966B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018537421A5 (https=) | ||
| JP7840836B2 (ja) | 改善された血清アルブミン結合性免疫グロブリン可変ドメイン | |
| JP7453206B2 (ja) | 改良された血清アルブミン結合剤 | |
| JP2020500510A5 (https=) | ||
| JP2020506898A5 (https=) | ||
| JP2020515518A5 (https=) | ||
| JP2017519503A5 (https=) | ||
| JP2020195399A5 (https=) | ||
| JP2020515518A (ja) | 改善された血清アルブミン結合剤 | |
| JP2019506841A5 (https=) | ||
| JP7821159B2 (ja) | Ｂｃｍａと結合する単一可変ドメイン及び抗原結合分子 | |
| JP2019501883A5 (https=) | ||
| JP2017522903A5 (https=) | ||
| JP2011509245A5 (https=) | ||
| TW201643193A (zh) | 一種抗ｐｄ－１的單克隆抗體及其獲得方法 | |
| JP2016524463A5 (https=) | ||
| IL317416A (en) | T cell-recruiting polypeptides capable of binding CD123 and TCR alpha/beta | |
| JP2019506839A (ja) | 改善されたｔｎｆ結合因子 | |
| JP2005528914A5 (https=) | ||
| JP2021512159A5 (https=) | ||
| JP2022504826A5 (https=) | ||
| JP2025530888A5 (https=) | ||
| JP2015012869A5 (https=) | ||
| JP7821161B2 (ja) | Ｂｃｍａと結合する単一可変ドメイン及び抗原結合分子 | |
| CA3164234A1 (en) | Multi-specific antibodies |