JP2025530888A5 - - Google Patents

Info

Publication number
JP2025530888A5
JP2025530888A5 JP2024573474A JP2024573474A JP2025530888A5 JP 2025530888 A5 JP2025530888 A5 JP 2025530888A5 JP 2024573474 A JP2024573474 A JP 2024573474A JP 2024573474 A JP2024573474 A JP 2024573474A JP 2025530888 A5 JP2025530888 A5 JP 2025530888A5
Authority
JP
Japan
Prior art keywords
isvd
amino acid
seq
optionally
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024573474A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025530888A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2023/065925 external-priority patent/WO2023242247A1/en
Publication of JP2025530888A publication Critical patent/JP2025530888A/ja
Publication of JP2025530888A5 publication Critical patent/JP2025530888A5/ja
Pending legal-status Critical Current

Links

JP2024573474A 2022-06-14 2023-06-14 T細胞レセプターを標的とするイムノグロブリン単一可変ドメイン Pending JP2025530888A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22305869 2022-06-14
EP22305869.4 2022-06-14
PCT/EP2023/065925 WO2023242247A1 (en) 2022-06-14 2023-06-14 Immunoglobulin single variable domains targeting t cell receptor

Publications (2)

Publication Number Publication Date
JP2025530888A JP2025530888A (ja) 2025-09-18
JP2025530888A5 true JP2025530888A5 (https=) 2026-04-22

Family

ID=82404277

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024573474A Pending JP2025530888A (ja) 2022-06-14 2023-06-14 T細胞レセプターを標的とするイムノグロブリン単一可変ドメイン

Country Status (13)

Country Link
US (1) US20240109965A1 (https=)
EP (1) EP4540286A1 (https=)
JP (1) JP2025530888A (https=)
KR (1) KR20250023503A (https=)
CN (1) CN119630705A (https=)
AR (1) AR129614A1 (https=)
AU (1) AU2023290487A1 (https=)
CA (1) CA3259417A1 (https=)
CO (1) CO2025000062A2 (https=)
IL (1) IL317588A (https=)
MX (1) MX2024015501A (https=)
TW (1) TW202415678A (https=)
WO (1) WO2023242247A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025051767A1 (en) * 2023-09-04 2025-03-13 Sanofi Polypeptides for use in the treatment of glypican-3-expressing tumours
WO2026052756A1 (en) 2024-09-05 2026-03-12 Ablynx Nv Her2 binding immunoglobulin single variable domains, constructs comprising the same and uses thereof
WO2026078159A1 (en) 2024-10-10 2026-04-16 Ablynx Nv Immune cell engagers and methods comprising the same

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1621554T4 (da) 1992-08-21 2012-12-17 Univ Bruxelles Immunoglobuliner blottet for lette kæder
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
DK1027439T3 (da) 1997-10-27 2010-05-10 Bac Ip Bv Multivalente antigenbindende proteiner
US7112324B1 (en) 1998-04-21 2006-09-26 Micromet Ag CD 19×CD3 specific polypeptides and uses thereof
EP3960855A1 (en) * 2001-12-28 2022-03-02 Chugai Seiyaku Kabushiki Kaisha Method for stabilizing proteins
WO2004041863A2 (en) 2002-11-08 2004-05-21 Ablynx N.V. Single domain antibodies directed against interferon- gamma and uses therefor
US8188223B2 (en) 2005-05-18 2012-05-29 Ablynx N.V. Serum albumin binding proteins
EP1940881B1 (en) 2005-10-11 2016-11-30 Amgen Research (Munich) GmbH Compositions comprising cross-species-specific antibodies and uses thereof
AU2007237501A1 (en) 2006-04-14 2007-10-25 Ablynx N.V. DP-78-like nanobodies
WO2008020079A1 (en) 2006-08-18 2008-02-21 Ablynx N.V. Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
SG10201805064SA (en) 2011-06-23 2018-07-30 Ablynx Nv Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
EP2723771B1 (en) 2011-06-23 2019-09-11 Ablynx NV Serum albumin binding proteins
EP4707303A2 (en) 2014-05-16 2026-03-11 Ablynx NV Improved immunoglobulin variable domains
DK3653221T5 (da) * 2015-02-19 2024-08-26 Compugen Ltd Anti-pvrig-antistoffer og anvendelsesfremgangsmåder
LT3611192T (lt) 2015-05-13 2025-06-25 Ablynx N.V. T ląstelių rekrutingo polipeptidai tcr alfa/beta reaktyvumo pagrindu
LT3374392T (lt) 2015-11-13 2022-01-25 Ablynx Nv Patobulinti serumo albuminą surišantys imunoglobulino kintami domenai
AU2016357460B2 (en) 2015-11-18 2023-07-27 Ablynx Nv Improved serum albumin binders
BR112019010061A2 (pt) 2016-11-16 2019-08-13 Ablynx Nv polipeptídeos de recrutamento de células t capazes de se ligarem ao cd123 e tcr alfa/beta
RU2022101604A (ru) 2016-12-07 2022-03-29 Аблинкс Нв Улучшенные отдельные вариабельные домены иммуноглобулина, связывающиеся с сывороточным альбумином
IL267897B2 (en) 2017-01-17 2025-02-01 Ablynx Nv Improved serum albumin binders
JP7219220B2 (ja) 2017-01-17 2023-02-07 アブリンクス エン.ヴェー. 改善された血清アルブミン結合剤
PH12023500013A1 (en) * 2020-12-04 2024-03-11 Tidal Therapeutics Inc Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
IL303740A (en) * 2020-12-18 2023-08-01 Sanofi Sa T cell recruiting polypeptides based on tcr alpha/beta reactivity
CA3205422A1 (en) * 2020-12-18 2022-06-23 Ablynx Nv Polypeptides comprising immunoglobulin single variable domains targeting glypican-3 and t cell receptor

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