JP2023505492A5 - - Google Patents
Info
- Publication number
- JP2023505492A5 JP2023505492A5 JP2022533410A JP2022533410A JP2023505492A5 JP 2023505492 A5 JP2023505492 A5 JP 2023505492A5 JP 2022533410 A JP2022533410 A JP 2022533410A JP 2022533410 A JP2022533410 A JP 2022533410A JP 2023505492 A5 JP2023505492 A5 JP 2023505492A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- polypeptide
- isvd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962944619P | 2019-12-06 | 2019-12-06 | |
| US62/944,619 | 2019-12-06 | ||
| EP20305056 | 2020-01-23 | ||
| EP20305056.2 | 2020-01-23 | ||
| EP20000090.9 | 2020-02-28 | ||
| EP20000090 | 2020-02-28 | ||
| EP20305216.2 | 2020-03-02 | ||
| EP20305216 | 2020-03-02 | ||
| PCT/EP2020/084430 WO2021110816A1 (en) | 2019-12-06 | 2020-12-03 | POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING TNFα AND IL-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023505492A JP2023505492A (ja) | 2023-02-09 |
| JP2023505492A5 true JP2023505492A5 (https=) | 2023-12-07 |
| JP7657797B2 JP7657797B2 (ja) | 2025-04-07 |
Family
ID=73642903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022533410A Active JP7657797B2 (ja) | 2019-12-06 | 2020-12-03 | TNFαおよびIL-23を標的化する免疫グロブリン単一可変ドメインを含むポリペプチド |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20210188963A1 (https=) |
| EP (1) | EP4069733A1 (https=) |
| JP (1) | JP7657797B2 (https=) |
| KR (1) | KR20220122652A (https=) |
| CN (1) | CN114981300B (https=) |
| AU (1) | AU2020396204A1 (https=) |
| BR (1) | BR112022009799A2 (https=) |
| CA (1) | CA3163877A1 (https=) |
| CO (1) | CO2022009239A2 (https=) |
| IL (1) | IL293561A (https=) |
| MX (1) | MX2022006880A (https=) |
| PH (1) | PH12022551214A1 (https=) |
| TW (1) | TW202134269A (https=) |
| WO (1) | WO2021110816A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL318433A (en) | 2014-05-16 | 2025-03-01 | Ablynx Nv | Improved immunoglobulin variable complexes |
| EP4707303A2 (en) | 2014-05-16 | 2026-03-11 | Ablynx NV | Improved immunoglobulin variable domains |
| WO2020144164A1 (en) | 2019-01-07 | 2020-07-16 | Bactolife Aps | Pathogen binding proteins |
| CN113710229B (zh) | 2019-02-25 | 2026-01-06 | 芝加哥大学 | 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物 |
| IL293561A (en) | 2019-12-06 | 2022-08-01 | Ablynx Nv | Polypeptides comprising immunoglobulin with one variable domain targeting TNFa and IL-23 |
| AR131494A1 (es) | 2022-12-23 | 2025-03-26 | Ablynx Nv | Vehículos de conjugación a base de proteína |
| TW202448926A (zh) | 2023-02-17 | 2024-12-16 | 比利時商艾伯霖克斯公司 | 結合新生兒fc受體之多肽 |
| EP4438614A1 (en) | 2023-03-31 | 2024-10-02 | Sanofi | Methods for purifying heteromultimeric antibodies |
| TW202542180A (zh) * | 2023-12-22 | 2025-11-01 | 比利時商艾伯霖克斯公司 | 用於位點特異性胺軛合的基於蛋白質的載體 |
| CN118687298A (zh) | 2024-07-29 | 2024-09-24 | 上海原能细胞生物低温设备有限公司 | 一种立式低温存储冰箱 |
| CN119371530B (zh) * | 2024-11-06 | 2025-05-20 | 北京科道博济生物科技有限公司 | 一种靶向il-23a的纳米抗体及其应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1621554T4 (da) | 1992-08-21 | 2012-12-17 | Univ Bruxelles | Immunoglobuliner blottet for lette kæder |
| EP0739981A1 (en) | 1995-04-25 | 1996-10-30 | Vrije Universiteit Brussel | Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes |
| DK1027439T3 (da) | 1997-10-27 | 2010-05-10 | Bac Ip Bv | Multivalente antigenbindende proteiner |
| WO2004041863A2 (en) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Single domain antibodies directed against interferon- gamma and uses therefor |
| US8188223B2 (en) | 2005-05-18 | 2012-05-29 | Ablynx N.V. | Serum albumin binding proteins |
| AU2007237501A1 (en) | 2006-04-14 | 2007-10-25 | Ablynx N.V. | DP-78-like nanobodies |
| WO2008020079A1 (en) | 2006-08-18 | 2008-02-21 | Ablynx N.V. | Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling |
| EP2650311A3 (en) * | 2007-11-27 | 2014-06-04 | Ablynx N.V. | Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same |
| SG10201805064SA (en) | 2011-06-23 | 2018-07-30 | Ablynx Nv | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| EP2723771B1 (en) | 2011-06-23 | 2019-09-11 | Ablynx NV | Serum albumin binding proteins |
| EP4707303A2 (en) * | 2014-05-16 | 2026-03-11 | Ablynx NV | Improved immunoglobulin variable domains |
| AR102417A1 (es) | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
| EP3365371B1 (en) * | 2015-10-22 | 2025-10-08 | Ablynx NV | Gitr agonists |
| NO2768984T3 (https=) | 2015-11-12 | 2018-06-09 | ||
| LT3374392T (lt) | 2015-11-13 | 2022-01-25 | Ablynx Nv | Patobulinti serumo albuminą surišantys imunoglobulino kintami domenai |
| AU2016357460B2 (en) | 2015-11-18 | 2023-07-27 | Ablynx Nv | Improved serum albumin binders |
| JP7540877B2 (ja) * | 2016-02-12 | 2024-08-27 | アブリンクス エン.ヴェー. | 免疫グロブリン単一可変ドメインの生成方法 |
| RU2022101604A (ru) | 2016-12-07 | 2022-03-29 | Аблинкс Нв | Улучшенные отдельные вариабельные домены иммуноглобулина, связывающиеся с сывороточным альбумином |
| IL267897B2 (en) | 2017-01-17 | 2025-02-01 | Ablynx Nv | Improved serum albumin binders |
| JP7219220B2 (ja) | 2017-01-17 | 2023-02-07 | アブリンクス エン.ヴェー. | 改善された血清アルブミン結合剤 |
| AR112341A1 (es) | 2017-08-02 | 2019-10-16 | Lilly Co Eli | ANTICUERPOS BIESPECÍFICOS ANTI-TNF- / ANTI-IL-23 DE IgG |
| IL293561A (en) | 2019-12-06 | 2022-08-01 | Ablynx Nv | Polypeptides comprising immunoglobulin with one variable domain targeting TNFa and IL-23 |
-
2020
- 2020-12-03 IL IL293561A patent/IL293561A/en unknown
- 2020-12-03 CA CA3163877A patent/CA3163877A1/en active Pending
- 2020-12-03 PH PH1/2022/551214A patent/PH12022551214A1/en unknown
- 2020-12-03 MX MX2022006880A patent/MX2022006880A/es unknown
- 2020-12-03 AU AU2020396204A patent/AU2020396204A1/en not_active Abandoned
- 2020-12-03 BR BR112022009799A patent/BR112022009799A2/pt not_active Application Discontinuation
- 2020-12-03 JP JP2022533410A patent/JP7657797B2/ja active Active
- 2020-12-03 CN CN202080083442.0A patent/CN114981300B/zh active Active
- 2020-12-03 WO PCT/EP2020/084430 patent/WO2021110816A1/en not_active Ceased
- 2020-12-03 EP EP20816198.4A patent/EP4069733A1/en active Pending
- 2020-12-03 KR KR1020227022860A patent/KR20220122652A/ko not_active Withdrawn
- 2020-12-04 US US17/111,689 patent/US20210188963A1/en not_active Abandoned
- 2020-12-04 TW TW109142821A patent/TW202134269A/zh unknown
-
2021
- 2021-10-15 US US17/502,332 patent/US11332525B2/en active Active
-
2022
- 2022-04-25 US US17/727,868 patent/US20220372128A1/en active Pending
- 2022-04-25 US US17/727,876 patent/US12528860B2/en active Active
- 2022-07-01 CO CONC2022/0009239A patent/CO2022009239A2/es unknown
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