JP2023505492A5 - - Google Patents

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Publication number
JP2023505492A5
JP2023505492A5 JP2022533410A JP2022533410A JP2023505492A5 JP 2023505492 A5 JP2023505492 A5 JP 2023505492A5 JP 2022533410 A JP2022533410 A JP 2022533410A JP 2022533410 A JP2022533410 A JP 2022533410A JP 2023505492 A5 JP2023505492 A5 JP 2023505492A5
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JP
Japan
Prior art keywords
amino acid
seq
acid sequence
polypeptide
isvd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022533410A
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English (en)
Japanese (ja)
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JP2023505492A (ja
JP7657797B2 (ja
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Priority claimed from PCT/EP2020/084430 external-priority patent/WO2021110816A1/en
Publication of JP2023505492A publication Critical patent/JP2023505492A/ja
Publication of JP2023505492A5 publication Critical patent/JP2023505492A5/ja
Application granted granted Critical
Publication of JP7657797B2 publication Critical patent/JP7657797B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022533410A 2019-12-06 2020-12-03 TNFαおよびIL-23を標的化する免疫グロブリン単一可変ドメインを含むポリペプチド Active JP7657797B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962944619P 2019-12-06 2019-12-06
US62/944,619 2019-12-06
EP20305056 2020-01-23
EP20305056.2 2020-01-23
EP20000090.9 2020-02-28
EP20000090 2020-02-28
EP20305216.2 2020-03-02
EP20305216 2020-03-02
PCT/EP2020/084430 WO2021110816A1 (en) 2019-12-06 2020-12-03 POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING TNFα AND IL-23

Publications (3)

Publication Number Publication Date
JP2023505492A JP2023505492A (ja) 2023-02-09
JP2023505492A5 true JP2023505492A5 (https=) 2023-12-07
JP7657797B2 JP7657797B2 (ja) 2025-04-07

Family

ID=73642903

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022533410A Active JP7657797B2 (ja) 2019-12-06 2020-12-03 TNFαおよびIL-23を標的化する免疫グロブリン単一可変ドメインを含むポリペプチド

Country Status (14)

Country Link
US (4) US20210188963A1 (https=)
EP (1) EP4069733A1 (https=)
JP (1) JP7657797B2 (https=)
KR (1) KR20220122652A (https=)
CN (1) CN114981300B (https=)
AU (1) AU2020396204A1 (https=)
BR (1) BR112022009799A2 (https=)
CA (1) CA3163877A1 (https=)
CO (1) CO2022009239A2 (https=)
IL (1) IL293561A (https=)
MX (1) MX2022006880A (https=)
PH (1) PH12022551214A1 (https=)
TW (1) TW202134269A (https=)
WO (1) WO2021110816A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL318433A (en) 2014-05-16 2025-03-01 Ablynx Nv Improved immunoglobulin variable complexes
EP4707303A2 (en) 2014-05-16 2026-03-11 Ablynx NV Improved immunoglobulin variable domains
WO2020144164A1 (en) 2019-01-07 2020-07-16 Bactolife Aps Pathogen binding proteins
CN113710229B (zh) 2019-02-25 2026-01-06 芝加哥大学 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物
IL293561A (en) 2019-12-06 2022-08-01 Ablynx Nv Polypeptides comprising immunoglobulin with one variable domain targeting TNFa and IL-23
AR131494A1 (es) 2022-12-23 2025-03-26 Ablynx Nv Vehículos de conjugación a base de proteína
TW202448926A (zh) 2023-02-17 2024-12-16 比利時商艾伯霖克斯公司 結合新生兒fc受體之多肽
EP4438614A1 (en) 2023-03-31 2024-10-02 Sanofi Methods for purifying heteromultimeric antibodies
TW202542180A (zh) * 2023-12-22 2025-11-01 比利時商艾伯霖克斯公司 用於位點特異性胺軛合的基於蛋白質的載體
CN118687298A (zh) 2024-07-29 2024-09-24 上海原能细胞生物低温设备有限公司 一种立式低温存储冰箱
CN119371530B (zh) * 2024-11-06 2025-05-20 北京科道博济生物科技有限公司 一种靶向il-23a的纳米抗体及其应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1621554T4 (da) 1992-08-21 2012-12-17 Univ Bruxelles Immunoglobuliner blottet for lette kæder
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
DK1027439T3 (da) 1997-10-27 2010-05-10 Bac Ip Bv Multivalente antigenbindende proteiner
WO2004041863A2 (en) 2002-11-08 2004-05-21 Ablynx N.V. Single domain antibodies directed against interferon- gamma and uses therefor
US8188223B2 (en) 2005-05-18 2012-05-29 Ablynx N.V. Serum albumin binding proteins
AU2007237501A1 (en) 2006-04-14 2007-10-25 Ablynx N.V. DP-78-like nanobodies
WO2008020079A1 (en) 2006-08-18 2008-02-21 Ablynx N.V. Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
EP2650311A3 (en) * 2007-11-27 2014-06-04 Ablynx N.V. Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
SG10201805064SA (en) 2011-06-23 2018-07-30 Ablynx Nv Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
EP2723771B1 (en) 2011-06-23 2019-09-11 Ablynx NV Serum albumin binding proteins
EP4707303A2 (en) * 2014-05-16 2026-03-11 Ablynx NV Improved immunoglobulin variable domains
AR102417A1 (es) 2014-11-05 2017-03-01 Lilly Co Eli Anticuerpos biespecíficos anti-tnf- / anti-il-23
EP3365371B1 (en) * 2015-10-22 2025-10-08 Ablynx NV Gitr agonists
NO2768984T3 (https=) 2015-11-12 2018-06-09
LT3374392T (lt) 2015-11-13 2022-01-25 Ablynx Nv Patobulinti serumo albuminą surišantys imunoglobulino kintami domenai
AU2016357460B2 (en) 2015-11-18 2023-07-27 Ablynx Nv Improved serum albumin binders
JP7540877B2 (ja) * 2016-02-12 2024-08-27 アブリンクス エン.ヴェー. 免疫グロブリン単一可変ドメインの生成方法
RU2022101604A (ru) 2016-12-07 2022-03-29 Аблинкс Нв Улучшенные отдельные вариабельные домены иммуноглобулина, связывающиеся с сывороточным альбумином
IL267897B2 (en) 2017-01-17 2025-02-01 Ablynx Nv Improved serum albumin binders
JP7219220B2 (ja) 2017-01-17 2023-02-07 アブリンクス エン.ヴェー. 改善された血清アルブミン結合剤
AR112341A1 (es) 2017-08-02 2019-10-16 Lilly Co Eli ANTICUERPOS BIESPECÍFICOS ANTI-TNF- / ANTI-IL-23 DE IgG
IL293561A (en) 2019-12-06 2022-08-01 Ablynx Nv Polypeptides comprising immunoglobulin with one variable domain targeting TNFa and IL-23

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