JP2017079785A5 - - Google Patents
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- JP2017079785A5 JP2017079785A5 JP2017003955A JP2017003955A JP2017079785A5 JP 2017079785 A5 JP2017079785 A5 JP 2017079785A5 JP 2017003955 A JP2017003955 A JP 2017003955A JP 2017003955 A JP2017003955 A JP 2017003955A JP 2017079785 A5 JP2017079785 A5 JP 2017079785A5
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- JP
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- Prior art keywords
- antibody
- amino acid
- seq
- acid sequence
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 108010065637 Interleukin-23 Proteins 0.000 claims 4
- 102000013264 Interleukin-23 Human genes 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 2
- 101000852980 Homo sapiens Interleukin-23 subunit alpha Proteins 0.000 claims 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000004681 Psoriasis Diseases 0.000 claims 2
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 2
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 208000030159 metabolic disease Diseases 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 208000023504 respiratory system disease Diseases 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 102100036672 Interleukin-23 receptor Human genes 0.000 claims 1
- 101710195550 Interleukin-23 receptor Proteins 0.000 claims 1
- 230000005784 autoimmunity Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 230000019491 signal transduction Effects 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41015810P | 2010-11-04 | 2010-11-04 | |
| US61/410,158 | 2010-11-04 | ||
| US41195310P | 2010-11-10 | 2010-11-10 | |
| US61/411,953 | 2010-11-10 | ||
| US41259410P | 2010-11-11 | 2010-11-11 | |
| US61/412,594 | 2010-11-11 | ||
| US201161448785P | 2011-03-03 | 2011-03-03 | |
| US61/448,785 | 2011-03-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537771A Division JP6126532B2 (ja) | 2010-11-04 | 2011-11-02 | 抗ｉｌ−２３抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018223469A Division JP6758361B2 (ja) | 2010-11-04 | 2018-11-29 | 抗ｉｌ−２３抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017079785A JP2017079785A (ja) | 2017-05-18 |
| JP2017079785A5 true JP2017079785A5 (https=) | 2017-06-29 |
| JP6445596B2 JP6445596B2 (ja) | 2018-12-26 |
Family
ID=44936573
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537771A Active JP6126532B2 (ja) | 2010-11-04 | 2011-11-02 | 抗ｉｌ−２３抗体 |
| JP2017003955A Active JP6445596B2 (ja) | 2010-11-04 | 2017-01-13 | 抗ｉｌ−２３抗体 |
| JP2018223469A Active JP6758361B2 (ja) | 2010-11-04 | 2018-11-29 | 抗ｉｌ−２３抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537771A Active JP6126532B2 (ja) | 2010-11-04 | 2011-11-02 | 抗ｉｌ−２３抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018223469A Active JP6758361B2 (ja) | 2010-11-04 | 2018-11-29 | 抗ｉｌ−２３抗体 |
Country Status (39)
Families Citing this family (44)
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| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| MX2019000046A (es) | 2010-11-04 | 2023-10-05 | Boehringer Ingelheim Int | Anticuerpos anti-il-23. |
| PL3326649T3 (pl) | 2012-05-03 | 2022-04-25 | Boehringer Ingelheim International Gmbh | Przeciwciała anty-il-23p19 |
| AR094877A1 (es) * | 2013-03-08 | 2015-09-02 | Lilly Co Eli | Anticuerpos que se unen a il-23 |
| SG11201507482UA (en) | 2013-03-15 | 2015-10-29 | Amgen Inc | Methods for treating psoriasis using an anti-il-23 antibody |
| SG11201507483PA (en) | 2013-03-15 | 2015-10-29 | Amgen Inc | Methods for treating crohn's disease using an anti-il23 antibody |
| EP3708679A1 (en) | 2014-07-24 | 2020-09-16 | Boehringer Ingelheim International GmbH | Biomarkers useful in the treatment of il-23a related diseases |
| EA202193002A2 (ru) | 2014-09-03 | 2022-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Соединение, нацеленное на ил-23a и фно-альфа, и его применение |
| AU2016215535B2 (en) | 2015-02-04 | 2021-09-16 | Boehringer Ingelheim International Gmbh | Methods of treating inflammatory diseases |
| KR20170135972A (ko) | 2015-04-14 | 2017-12-08 | 베링거 인겔하임 인터내셔날 게엠베하 | 질환을 치료하는 방법 |
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| CN108290058B (zh) * | 2015-09-17 | 2023-05-16 | 美国安进公司 | 使用il23途径生物标志物预测il23拮抗剂的临床应答 |
| TWI811716B (zh) | 2015-09-18 | 2023-08-11 | 德商百靈佳殷格翰國際股份有限公司 | 治療發炎性疾病之方法 |
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| TWI744617B (zh) * | 2018-03-30 | 2021-11-01 | 美商美國禮來大藥廠 | 治療潰瘍性結腸炎之方法 |
| CN112689643A (zh) | 2018-07-13 | 2021-04-20 | 阿斯特捷利康合作创业有限责任公司 | 用布雷库单抗治疗溃疡性结肠炎 |
| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| CN109810947B (zh) * | 2019-01-18 | 2021-06-11 | 北京贝来生物科技有限公司 | 一种抑制Th17细胞活化的间充质干细胞及其制备方法和应用 |
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| TW202535466A (zh) * | 2019-09-09 | 2025-09-16 | 德商百靈佳殷格翰國際股份有限公司 | 抗-il-23p19抗體調配物 |
| JP7758672B2 (ja) * | 2019-12-20 | 2025-10-22 | ノヴァロック バイオセラピューティクス， リミテッド | 抗インターロイキン－２３ ｐ１９抗体およびそれの使用方法 |
| CN111956606B (zh) * | 2020-08-31 | 2021-05-14 | 江苏荃信生物医药有限公司 | 包含高浓度抗人白介素23单克隆抗体的低粘度液体制剂 |
| TW202428304A (zh) | 2020-09-10 | 2024-07-16 | 美商美國禮來大藥廠 | 治療性抗體調配物 |
| TW202231292A (zh) | 2020-10-13 | 2022-08-16 | 美商健生生物科技公司 | 用於調節分化簇ｉｖ及／或ｖｉｉｉ的經生物工程改造之ｔ細胞介導之免疫力、材料、及其他方法 |
| JP2024521748A (ja) | 2021-05-28 | 2024-06-04 | イーライ リリー アンド カンパニー | 潰瘍性大腸炎に関与する遺伝子の抗ｉｌ－２３ｐ１９抗体調節 |
| KR102761841B1 (ko) | 2021-07-09 | 2025-02-05 | 연세대학교 산학협력단 | Il-23에 의해 매개되는 질환의 중증도 예측용 조성물 |
| WO2023056417A1 (en) | 2021-09-30 | 2023-04-06 | Eli Lilly And Company | Anti-il-23p19 antibody regulation of genes involved in bowel urgency in ulcerative colitis |
| WO2024077113A1 (en) | 2022-10-06 | 2024-04-11 | Eli Lilly And Company | Methods of treating fatigue in ulcerative colitis |
| WO2024085697A1 (en) | 2022-10-21 | 2024-04-25 | Chong Kun Dang Pharmaceutical Corp. | Stable antibody composition |
| KR20250152080A (ko) | 2023-02-22 | 2025-10-22 | 일라이 릴리 앤드 캄파니 | 궤양성 결장염에서의 유전자의 조절 및 그의 용도 |
| CN121358765A (zh) * | 2023-06-22 | 2026-01-16 | 派拉冈医疗公司 | Il-23抗体组合物以及使用方法 |
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| TW202540172A (zh) * | 2024-02-06 | 2025-10-16 | 美商派拉岡醫療公司 | Ｉｌ－２３結合蛋白組合物及使用方法 |
| WO2025170982A2 (en) * | 2024-02-06 | 2025-08-14 | Paragon Therapeutics, Inc. | Il-23 antibody compositions and methods of use |
| CN117875575B (zh) * | 2024-03-12 | 2024-05-28 | 中国电子科技集团公司第二十九研究所 | 一种基于混合仿生算法的干扰资源分配方法 |
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