JP2023531493A5 - - Google Patents
Info
- Publication number
- JP2023531493A5 JP2023531493A5 JP2022578995A JP2022578995A JP2023531493A5 JP 2023531493 A5 JP2023531493 A5 JP 2023531493A5 JP 2022578995 A JP2022578995 A JP 2022578995A JP 2022578995 A JP2022578995 A JP 2022578995A JP 2023531493 A5 JP2023531493 A5 JP 2023531493A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- variable domain
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063045041P | 2020-06-26 | 2020-06-26 | |
| US63/045,041 | 2020-06-26 | ||
| US202063199218P | 2020-12-14 | 2020-12-14 | |
| US63/199,218 | 2020-12-14 | ||
| PCT/US2021/039191 WO2021263167A2 (en) | 2020-06-26 | 2021-06-25 | Il-10 muteins and fusion proteins thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023531493A JP2023531493A (ja) | 2023-07-24 |
| JP2023531493A5 true JP2023531493A5 (https=) | 2024-06-19 |
Family
ID=77071744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022578995A Pending JP2023531493A (ja) | 2020-06-26 | 2021-06-25 | Ｉｌ－１０突然変異タンパク質及びその融合タンパク質 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20230265145A1 (https=) |
| EP (1) | EP4172184A2 (https=) |
| JP (1) | JP2023531493A (https=) |
| KR (1) | KR20230027300A (https=) |
| CN (1) | CN116209459A (https=) |
| AU (1) | AU2021296917A1 (https=) |
| CA (1) | CA3187576A1 (https=) |
| CL (3) | CL2022003755A1 (https=) |
| CO (1) | CO2023000431A2 (https=) |
| CR (1) | CR20230025A (https=) |
| IL (1) | IL299149A (https=) |
| JO (1) | JOP20220348A1 (https=) |
| MX (1) | MX2022016548A (https=) |
| PE (1) | PE20231082A1 (https=) |
| TW (1) | TW202216743A (https=) |
| UY (1) | UY39298A (https=) |
| WO (1) | WO2021263167A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118240058A (zh) * | 2022-12-24 | 2024-06-25 | 广东菲鹏制药股份有限公司 | Il10突变体、融合蛋白和药物 |
| CN116425857B (zh) * | 2023-06-09 | 2023-08-18 | 苏州依科赛生物科技股份有限公司 | 一种无糖基化修饰的il-15及制备方法 |
| CN117143235B (zh) * | 2023-10-26 | 2024-02-09 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种单克隆抗体及应用 |
| CN121108363A (zh) * | 2024-06-12 | 2025-12-12 | 广东菲鹏制药股份有限公司 | 一种融合蛋白及其用途 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| CA2722378C (en) | 1996-12-03 | 2015-02-03 | Amgen Fremont Inc. | Human antibodies that bind tnf.alpha. |
| DE19851675A1 (de) * | 1998-11-10 | 2000-05-11 | Bayer Ag | Menschliche Interleukin-10 Mutantenproteine |
| US6833268B1 (en) | 1999-06-10 | 2004-12-21 | Abgenix, Inc. | Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions |
| PL354286A1 (en) | 1999-08-23 | 2003-12-29 | Dana-Farber Cancer Institutedana-Farber Cancer Institute | Pd-1, a receptor for b7-4, and uses therefor |
| AU2003281200A1 (en) | 2002-07-03 | 2004-01-23 | Tasuku Honjo | Immunopotentiating compositions |
| AU2003280315A1 (en) * | 2002-11-14 | 2004-06-03 | Maxygen, Inc. | Conjugates of interleukin-10 and polymers |
| CN101899114A (zh) | 2002-12-23 | 2010-12-01 | 惠氏公司 | 抗pd-1抗体及其用途 |
| US7563869B2 (en) | 2003-01-23 | 2009-07-21 | Ono Pharmaceutical Co., Ltd. | Substance specific to human PD-1 |
| DK2439273T3 (da) | 2005-05-09 | 2019-06-03 | Ono Pharmaceutical Co | Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika |
| PT1907424E (pt) | 2005-07-01 | 2015-10-09 | Squibb & Sons Llc | Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1) |
| US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
| US20080260820A1 (en) * | 2007-04-19 | 2008-10-23 | Gilles Borrelly | Oral dosage formulations of protease-resistant polypeptides |
| BR122017025062B8 (pt) | 2007-06-18 | 2021-07-27 | Merck Sharp & Dohme | anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento |
| WO2009014708A2 (en) | 2007-07-23 | 2009-01-29 | Cell Genesys, Inc. | Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof |
| AU2009290544B2 (en) | 2008-09-12 | 2015-07-16 | Oxford University Innovation Limited | PD-1 specific antibodies and uses thereof |
| US8552154B2 (en) | 2008-09-26 | 2013-10-08 | Emory University | Anti-PD-L1 antibodies and uses therefor |
| KR101050829B1 (ko) | 2008-10-02 | 2011-07-20 | 서울대학교산학협력단 | 항 ｐｄ-1 항체 또는 항 ｐｄ-ｌ1 항체를 포함하는 항암제 |
| EP3255060A1 (en) | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| JP5844159B2 (ja) | 2009-02-09 | 2016-01-13 | ユニヴェルシテ デクス−マルセイユＵｎｉｖｅｒｓｉｔｅ Ｄ’Ａｉｘ−Ｍａｒｓｅｉｌｌｅ | Ｐｄ−１抗体およびｐｄ−ｌ１抗体ならびにその使用 |
| EA201892619A1 (ru) * | 2011-04-29 | 2019-04-30 | Роше Гликарт Аг | Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2 |
| AU2013311606B2 (en) | 2012-09-07 | 2017-10-05 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (TREM-1) Trem-Like Transcript 1 (TLT-1) and uses thereof |
| EP2989240A4 (en) * | 2013-04-24 | 2016-10-19 | Armo Biosciences Inc | INTERLEUKIN-10 COMPOSITIONS AND USES THEREOF |
| PL3369435T3 (pl) * | 2013-07-18 | 2020-04-30 | Xalud Therapeutics, Inc. | Kompozycja do leczenia choroby zapalnej stawów |
| CN112552401B (zh) | 2013-09-13 | 2023-08-25 | 广州百济神州生物制药有限公司 | 抗pd1抗体及其作为治疗剂与诊断剂的用途 |
| WO2015117930A1 (en) * | 2014-02-06 | 2015-08-13 | F. Hoffmann-La Roche Ag | Interleukine 10 immunoconjugates |
| WO2017152102A2 (en) * | 2016-03-04 | 2017-09-08 | Alector Llc | Anti-trem1 antibodies and methods of use thereof |
| TW201930344A (zh) | 2018-01-12 | 2019-08-01 | 美商安進公司 | 抗ｐｄ-１抗體及治療方法 |
-
2021
- 2021-06-25 PE PE2022003048A patent/PE20231082A1/es unknown
- 2021-06-25 UY UY0001039298A patent/UY39298A/es unknown
- 2021-06-25 EP EP21746606.9A patent/EP4172184A2/en active Pending
- 2021-06-25 US US18/001,913 patent/US20230265145A1/en active Pending
- 2021-06-25 IL IL299149A patent/IL299149A/en unknown
- 2021-06-25 MX MX2022016548A patent/MX2022016548A/es unknown
- 2021-06-25 CN CN202180051906.4A patent/CN116209459A/zh active Pending
- 2021-06-25 WO PCT/US2021/039191 patent/WO2021263167A2/en not_active Ceased
- 2021-06-25 AU AU2021296917A patent/AU2021296917A1/en active Pending
- 2021-06-25 JP JP2022578995A patent/JP2023531493A/ja active Pending
- 2021-06-25 CA CA3187576A patent/CA3187576A1/en active Pending
- 2021-06-25 TW TW110123422A patent/TW202216743A/zh unknown
- 2021-06-25 KR KR1020237003104A patent/KR20230027300A/ko active Pending
- 2021-06-25 CR CR20230025A patent/CR20230025A/es unknown
-
2022
- 2022-12-22 JO JOJO/P/2022/0348A patent/JOP20220348A1/ar unknown
- 2022-12-26 CL CL2022003755A patent/CL2022003755A1/es unknown
-
2023
- 2023-01-16 CO CONC2023/0000431A patent/CO2023000431A2/es unknown
-
2024
- 2024-11-26 CL CL2024003618A patent/CL2024003618A1/es unknown
- 2024-11-26 CL CL2024003619A patent/CL2024003619A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023531493A5 (https=) | ||
| JP2024038040A5 (https=) | ||
| EP3072905B1 (en) | Il-17a binding agent and uses thereof | |
| JP2020521452A5 (https=) | ||
| CN103154029B (zh) | 抗人tweak的抗体及其用途 | |
| RU2007129676A (ru) | Антитела к рецептору альфа 1 il-13 и их применение | |
| RU2011101969A (ru) | Антитела к человеческому интерлейкину-20 | |
| JP2023505492A5 (https=) | ||
| CN106459216A (zh) | 多特异性抗体构建体 | |
| JP2019522961A5 (https=) | ||
| JP2020505386A5 (https=) | ||
| TW201917135A (zh) | 抗ＴＮＦ／抗ＩＬ-２３ ＩｇＧ雙特異性抗體 | |
| JP2007530435A5 (https=) | ||
| RU2008129787A (ru) | Фармацевтические композиции с устойчивостью к растворимому сеа | |
| CN101679516A (zh) | 靶向金黄色葡萄球菌ORF0657n的抗原结合蛋白 | |
| EP3464349A2 (en) | Compositions and methods for antibodies targeting staphylococcal leukotoxins | |
| CN108473568A (zh) | 对TNF-α、IL-17A和IL-17F具有特异性的多特异性抗体分子 | |
| JP2023015301A5 (https=) | ||
| JP6949012B2 (ja) | Ｂ型肝炎表面抗原に対する抗体及びその使用 | |
| JPWO2012026309A1 (ja) | 抗ｐａｄ４抗体医薬の創成 | |
| JP2022513043A5 (https=) | ||
| JP2023553694A5 (https=) | ||
| CA3077304A1 (en) | Anti-pacap antibody | |
| JP2018525032A5 (https=) | ||
| WO2020090892A1 (ja) | 抗ヒトＦｎ１４抗体 |