JP2021102633A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021102633A5 JP2021102633A5 JP2021047470A JP2021047470A JP2021102633A5 JP 2021102633 A5 JP2021102633 A5 JP 2021102633A5 JP 2021047470 A JP2021047470 A JP 2021047470A JP 2021047470 A JP2021047470 A JP 2021047470A JP 2021102633 A5 JP2021102633 A5 JP 2021102633A5
- Authority
- JP
- Japan
- Prior art keywords
- binding protein
- fragment
- seq
- chain variable
- variable domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022067548A JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662288912P | 2016-01-29 | 2016-01-29 | |
| US62/288,912 | 2016-01-29 | ||
| JP2018559164A JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559164A Division JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022067548A Division JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021102633A JP2021102633A (ja) | 2021-07-15 |
| JP2021102633A5 true JP2021102633A5 (https=) | 2021-11-11 |
| JP7140867B2 JP7140867B2 (ja) | 2022-09-21 |
Family
ID=59386438
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559164A Active JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
| JP2021047470A Active JP7140867B2 (ja) | 2016-01-29 | 2021-03-22 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
| JP2022067548A Pending JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559164A Active JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022067548A Pending JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10118963B2 (https=) |
| EP (1) | EP3408400B1 (https=) |
| JP (3) | JP6883590B2 (https=) |
| KR (2) | KR20260041830A (https=) |
| CN (2) | CN116333124A (https=) |
| AU (1) | AU2017212717B2 (https=) |
| BR (1) | BR112018015480A2 (https=) |
| CA (1) | CA3013051A1 (https=) |
| CL (1) | CL2018002034A1 (https=) |
| EA (1) | EA037855B1 (https=) |
| ES (1) | ES2986360T3 (https=) |
| IL (1) | IL260846B2 (https=) |
| MX (2) | MX2018009228A (https=) |
| PH (1) | PH12018501611A1 (https=) |
| SG (1) | SG11201806496SA (https=) |
| TW (1) | TWI760323B (https=) |
| WO (1) | WO2017132562A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1204557A1 (en) * | 2012-05-31 | 2015-11-27 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind pd-l1 |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| EA037855B1 (ru) | 2016-01-29 | 2021-05-27 | Сорренто Терапьютикс, Инк. | Полностью человеческое антитело класса igg, связывающееся с эпитопом pd-l1 |
| KR102379464B1 (ko) | 2016-06-20 | 2022-03-29 | 키맵 리미티드 | 항-pd-l1 항체 |
| US9567399B1 (en) | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
| EP3534947A1 (en) | 2016-11-03 | 2019-09-11 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses & methods |
| CN119899267A (zh) * | 2018-03-22 | 2025-04-29 | 赛因格先进生物技术弗朗哥塞尔瓦托有限责任公司 | 拮抗性pd-1、pd-l1和lag-3结合蛋白 |
| AU2018418224B2 (en) | 2018-04-09 | 2025-04-17 | Oricell Therapeutics Co., Ltd. | Anti-PD-L1 antibody and use thereof |
| WO2019227490A1 (en) | 2018-06-01 | 2019-12-05 | Tayu Huaxia Biotech Medical Group Co., Ltd. | Compositions and methods for imaging |
| KR20210056288A (ko) * | 2018-06-01 | 2021-05-18 | 타유 후아시아 바이오테크 메디컬 그룹 컴퍼니 리미티드 | 질환 또는 병태를 치료하기 위한 조성물 및 그의 용도 |
| US12391758B2 (en) | 2018-08-20 | 2025-08-19 | 1Globe Biomedical Co., Ltd. | Anti-PD-L1 cancer immunotherapy antibodies |
| EP3893902B1 (en) * | 2018-12-11 | 2024-10-23 | Sanford Burnham Prebys Medical Discovery Institute | Inhibitors of pd-l1 activity or expression for use in the treatment of serrated colorectal cancer |
| WO2020151572A1 (en) | 2019-01-23 | 2020-07-30 | Tayu Huaxia Biotech Medical Group Co., Ltd. | Anti-pd-l1 diabodies and the use thereof |
| WO2020215020A1 (en) * | 2019-04-18 | 2020-10-22 | Qlsf Biotherapeutics Inc. | Humanized anti-pd-l1 antibodies |
| WO2021037007A1 (zh) * | 2019-08-29 | 2021-03-04 | 荣昌生物制药(烟台)股份有限公司 | 抗pd-l1抗体及其应用 |
| MX2023000005A (es) * | 2020-06-26 | 2023-03-06 | Sorrento Therapeutics Inc | Virus del herpes simple (vhs) oncolíticos que expresan proteínas de fusión inmunomoduladoras. |
| EP4208204A1 (en) | 2020-09-02 | 2023-07-12 | Mayo Foundation for Medical Education and Research | Antibody-nanoparticle complexes and methods for making and using the same |
| JP2023552694A (ja) | 2020-11-16 | 2023-12-19 | イミューンオンシア セラピューティクス インコーポレイテッド | 免疫抗がん剤に対する治療反応性を予測するためのバイオマーカーおよびその用途 |
| MX2023012995A (es) | 2021-05-07 | 2023-12-14 | Immuneoncia Therapeutics Inc | Anticuerpo biespecífico que se enlaza específicamente a cd47 y pd-l1. |
| US20240279339A1 (en) | 2021-06-09 | 2024-08-22 | Vivasor, Inc. | Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device |
| CA3267341A1 (en) * | 2022-09-19 | 2024-03-28 | Sonoma Biotherapeutics, Inc. | Specific chimeric antigen receptors for a citrullinated antigen to target regulatory T lymphocytes for the treatment of hidradenitis suppurativa |
| WO2024160721A1 (en) | 2023-01-30 | 2024-08-08 | Kymab Limited | Antibodies |
| TW202544031A (zh) * | 2024-02-29 | 2025-11-16 | 南韓商柳韓洋行股份有限公司 | 抗tigit/抗pd-l1雙特異性抗體及其用途 |
| IL323020A (en) * | 2024-04-13 | 2026-03-01 | Immuneoncia Therapeutics Inc | Neoadjuvant immunotherapy with a PD-L1 inhibitor for cancer treatment |
| KR20250165706A (ko) | 2024-04-13 | 2025-11-27 | 주식회사 이뮨온시아 | 암 치료를 위한 pd-l1 저해제를 이용한 신보조요법 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3817827A (en) | 1972-03-30 | 1974-06-18 | Scott Paper Co | Soft absorbent fibrous webs containing elastomeric bonding material and formed by creping and embossing |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4002531A (en) | 1976-01-22 | 1977-01-11 | Pierce Chemical Company | Modifying enzymes with polyethylene glycol and product produced thereby |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US6010902A (en) | 1988-04-04 | 2000-01-04 | Bristol-Meyers Squibb Company | Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity |
| US5766897A (en) | 1990-06-21 | 1998-06-16 | Incyte Pharmaceuticals, Inc. | Cysteine-pegylated proteins |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| JP3051145B2 (ja) | 1990-08-28 | 2000-06-12 | 住友製薬株式会社 | 新規なポリエチレングリコール誘導体修飾ペプチド |
| US5582996A (en) | 1990-12-04 | 1996-12-10 | The Wistar Institute Of Anatomy & Biology | Bifunctional antibodies and method of preparing same |
| DE4118120A1 (de) | 1991-06-03 | 1992-12-10 | Behringwerke Ag | Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US5281698A (en) | 1991-07-23 | 1994-01-25 | Cetus Oncology Corporation | Preparation of an activated polymer ester for protein conjugation |
| WO1993006217A1 (en) | 1991-09-19 | 1993-04-01 | Genentech, Inc. | EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES |
| JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化ｂ−ｂ１０ |
| AU673190B2 (en) | 1992-07-13 | 1996-10-31 | Bionebraska, Inc. | Method for modification of recombinant polypeptides |
| US5382657A (en) | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
| ATE240394T1 (de) | 1992-10-23 | 2003-05-15 | Immunex Corp | Methoden zur herstellung löslicher, oligomerer proteine |
| US5446090A (en) | 1993-11-12 | 1995-08-29 | Shearwater Polymers, Inc. | Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| US5840523A (en) | 1995-03-01 | 1998-11-24 | Genetech, Inc. | Methods and compositions for secretion of heterologous polypeptides |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| EP1105427A2 (en) | 1998-08-17 | 2001-06-13 | Abgenix, Inc. | Generation of modified molecules with increased serum half-lives |
| GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
| US6938003B2 (en) | 2000-06-30 | 2005-08-30 | Mahesh Harpale | Method and apparatus for a credibility reporting system to augment an online exchange |
| US7052686B2 (en) | 2000-09-29 | 2006-05-30 | Schering Corporation | Pegylated interleukin-10 |
| GB0025144D0 (en) | 2000-10-13 | 2000-11-29 | Medical Res Council | Concatenated nucleic acid sequences |
| US20040202995A1 (en) | 2003-04-09 | 2004-10-14 | Domantis | Nucleic acids, proteins, and screening methods |
| US7902338B2 (en) * | 2003-07-31 | 2011-03-08 | Immunomedics, Inc. | Anti-CD19 antibodies |
| SI2162149T1 (sl) | 2007-06-01 | 2014-04-30 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Cepivo za preprečevanje relapsa raka na dojki |
| US8877688B2 (en) * | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| HK1204557A1 (en) | 2012-05-31 | 2015-11-27 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind pd-l1 |
| CA2886433C (en) | 2012-10-04 | 2022-01-04 | Dana-Farber Cancer Institute, Inc. | Human monoclonal anti-pd-l1 antibodies and methods of use |
| AR093984A1 (es) * | 2012-12-21 | 2015-07-01 | Merck Sharp & Dohme | Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano |
| US9676853B2 (en) * | 2013-05-31 | 2017-06-13 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind PD-1 |
| WO2015154052A1 (en) * | 2014-04-04 | 2015-10-08 | Mayo Foundation For Medical Education And Research | Isotyping immunoglobulins using accurate molecular mass |
| CN105238762A (zh) * | 2015-10-26 | 2016-01-13 | 无锡傲锐东源生物科技有限公司 | 抗pd-1蛋白单克隆抗体杂交瘤细胞及其产生的抗pd-1单克隆抗体和应用 |
| EA037855B1 (ru) * | 2016-01-29 | 2021-05-27 | Сорренто Терапьютикс, Инк. | Полностью человеческое антитело класса igg, связывающееся с эпитопом pd-l1 |
-
2017
- 2017-01-27 EA EA201891709A patent/EA037855B1/ru unknown
- 2017-01-27 JP JP2018559164A patent/JP6883590B2/ja active Active
- 2017-01-27 KR KR1020267004206A patent/KR20260041830A/ko active Pending
- 2017-01-27 BR BR112018015480-6A patent/BR112018015480A2/pt not_active Application Discontinuation
- 2017-01-27 US US15/418,514 patent/US10118963B2/en active Active
- 2017-01-27 AU AU2017212717A patent/AU2017212717B2/en active Active
- 2017-01-27 ES ES17745008T patent/ES2986360T3/es active Active
- 2017-01-27 WO PCT/US2017/015429 patent/WO2017132562A1/en not_active Ceased
- 2017-01-27 CA CA3013051A patent/CA3013051A1/en active Pending
- 2017-01-27 CN CN202210999239.9A patent/CN116333124A/zh active Pending
- 2017-01-27 KR KR1020187024978A patent/KR102927822B1/ko active Active
- 2017-01-27 SG SG11201806496SA patent/SG11201806496SA/en unknown
- 2017-01-27 MX MX2018009228A patent/MX2018009228A/es unknown
- 2017-01-27 EP EP17745008.7A patent/EP3408400B1/en active Active
- 2017-01-27 CN CN201780021396.XA patent/CN109715821B/zh active Active
- 2017-02-02 TW TW106103519A patent/TWI760323B/zh active
-
2018
- 2018-07-27 MX MX2022011659A patent/MX2022011659A/es unknown
- 2018-07-27 CL CL2018002034A patent/CL2018002034A1/es unknown
- 2018-07-29 IL IL260846A patent/IL260846B2/en unknown
- 2018-07-30 PH PH12018501611A patent/PH12018501611A1/en unknown
- 2018-10-10 US US16/156,895 patent/US10919964B2/en active Active
-
2021
- 2021-01-13 US US17/148,450 patent/US11919952B2/en active Active
- 2021-03-22 JP JP2021047470A patent/JP7140867B2/ja active Active
-
2022
- 2022-04-15 JP JP2022067548A patent/JP2022095910A/ja active Pending
-
2024
- 2024-01-12 US US18/412,102 patent/US20240190959A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021102633A5 (https=) | ||
| JP2022058932A5 (https=) | ||
| JP2016521692A5 (https=) | ||
| TWI659969B (zh) | 一種抗ｐｄ－１的單株抗體及其獲得方法 | |
| CN108250296B (zh) | 全人源抗人pd-l1单克隆抗体及其应用 | |
| JP2018510151A5 (https=) | ||
| TWI821474B (zh) | Ｃｄ３抗體及其藥物用途 | |
| JP2018504105A5 (https=) | ||
| JP2021502104A5 (https=) | ||
| JP2019507183A5 (https=) | ||
| JP2015519375A5 (https=) | ||
| JP2021525546A5 (https=) | ||
| JP2021532058A5 (https=) | ||
| JP2019214586A5 (https=) | ||
| CN112969476B (zh) | 多特异性蛋白分子 | |
| JP2020525032A5 (https=) | ||
| JP2020500523A5 (https=) | ||
| JP2020510422A5 (https=) | ||
| HRP20220131T1 (hr) | Nova terapija s t-staničnim receptorima i imunološka terapija koja koristi iste | |
| JP2018532766A5 (https=) | ||
| JP2012501669A5 (https=) | ||
| JP2019507135A5 (https=) | ||
| JP2013506428A5 (https=) | ||
| RU2017121326A (ru) | Общие легкие цепи и способы их применения | |
| RU2009128064A (ru) | Антитела к cd44 |