JP2021102633A5 - - Google Patents
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- Publication number
- JP2021102633A5 JP2021102633A5 JP2021047470A JP2021047470A JP2021102633A5 JP 2021102633 A5 JP2021102633 A5 JP 2021102633A5 JP 2021047470 A JP2021047470 A JP 2021047470A JP 2021047470 A JP2021047470 A JP 2021047470A JP 2021102633 A5 JP2021102633 A5 JP 2021102633A5
- Authority
- JP
- Japan
- Prior art keywords
- binding protein
- fragment
- seq
- chain variable
- variable domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022067548A JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662288912P | 2016-01-29 | 2016-01-29 | |
| US62/288,912 | 2016-01-29 | ||
| JP2018559164A JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559164A Division JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022067548A Division JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021102633A JP2021102633A (ja) | 2021-07-15 |
| JP2021102633A5 true JP2021102633A5 (https=) | 2021-11-11 |
| JP7140867B2 JP7140867B2 (ja) | 2022-09-21 |
Family
ID=59386438
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559164A Active JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
| JP2021047470A Active JP7140867B2 (ja) | 2016-01-29 | 2021-03-22 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
| JP2022067548A Pending JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559164A Active JP6883590B2 (ja) | 2016-01-29 | 2017-01-27 | Ｐｄ−ｌ１に結合する抗原結合性タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022067548A Pending JP2022095910A (ja) | 2016-01-29 | 2022-04-15 | Ｐｄ－ｌ１に結合する抗原結合性タンパク質 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10118963B2 (https=) |
| EP (1) | EP3408400B1 (https=) |
| JP (3) | JP6883590B2 (https=) |
| KR (2) | KR102927822B1 (https=) |
| CN (2) | CN109715821B (https=) |
| AU (1) | AU2017212717B2 (https=) |
| BR (1) | BR112018015480A2 (https=) |
| CA (1) | CA3013051A1 (https=) |
| CL (1) | CL2018002034A1 (https=) |
| EA (1) | EA037855B1 (https=) |
| ES (1) | ES2986360T3 (https=) |
| IL (1) | IL260846B2 (https=) |
| MX (2) | MX2018009228A (https=) |
| PH (1) | PH12018501611A1 (https=) |
| SG (1) | SG11201806496SA (https=) |
| TW (1) | TWI760323B (https=) |
| WO (1) | WO2017132562A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220084444A (ko) | 2012-05-31 | 2022-06-21 | 소렌토 쎄라퓨틱스, 인코포레이티드 | Pd-l1에 결합하는 항원 결합 단백질 |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| WO2017132562A1 (en) * | 2016-01-29 | 2017-08-03 | Heyue Zhou | Antigen binding proteins that bind pd-l1 |
| US9567399B1 (en) | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
| RU2769282C2 (ru) | 2016-06-20 | 2022-03-30 | Кимаб Лимитед | Анти-PD-L1 и IL-2 цитокины |
| EP3534947A1 (en) | 2016-11-03 | 2019-09-11 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses & methods |
| MX2020009550A (es) * | 2018-03-22 | 2020-11-11 | Keires Ag | Proteinas de union a antigeno antagonistas. |
| MX2020010653A (es) | 2018-04-09 | 2020-10-28 | Origincell Therapeutics Co Ltd | Anticuerpo anti-muerte programada-ligando 1 y su uso. |
| EP3818085A4 (en) * | 2018-06-01 | 2022-03-09 | Tayu Huaxia Biotech Medical Group Co., Ltd. | COMPOSITIONS AND THEIR USES FOR THE TREATMENT OF DISEASES OR DISORDERS |
| WO2019227490A1 (en) | 2018-06-01 | 2019-12-05 | Tayu Huaxia Biotech Medical Group Co., Ltd. | Compositions and methods for imaging |
| MX2021002077A (es) * | 2018-08-20 | 2021-05-27 | 1Globe Biomedical Co Ltd | Nuevas composiciones de anticuerpos para la inmunoterapia contra el cáncer. |
| US20220177561A1 (en) * | 2018-12-11 | 2022-06-09 | Sanford Burnham Prebys Medical Discovery Institute | Models and Methods Useful for the Treatment of Serrated Colorectal Cancer |
| CN113795511B (zh) | 2019-01-23 | 2024-07-23 | 大有华夏生物医药集团有限公司 | 抗pd-l1双抗体及其用途 |
| JP7725066B2 (ja) * | 2019-04-18 | 2025-08-19 | キューエルエスエフ バイオセラピューティック インコーポレイテッド | ヒト化抗ｐｄ－ｌ１抗体 |
| KR20220012856A (ko) * | 2019-08-29 | 2022-02-04 | 레메젠 코, 리미티드 | 항 ｐｄ―ｌ１ 항체 및 그의 용도 |
| JP2023532279A (ja) * | 2020-06-26 | 2023-07-27 | ソレント・セラピューティクス・インコーポレイテッド | 免疫調節性融合タンパク質を発現する腫瘍溶解性単純ヘルペスウイルス（ｈｓｖ） |
| EP4208204A1 (en) | 2020-09-02 | 2023-07-12 | Mayo Foundation for Medical Education and Research | Antibody-nanoparticle complexes and methods for making and using the same |
| TWI907564B (zh) | 2020-11-16 | 2025-12-11 | 南韓商益免安協公司 | 用於預測對免疫抗癌劑的治療反應的生物標誌物及其用途 |
| CA3219221A1 (en) * | 2021-05-07 | 2022-11-10 | Immuneoncia Therapeutics, Inc. | Bispecific antibody specifically binding to cd47 and pd-l1 |
| WO2022261262A1 (en) | 2021-06-09 | 2022-12-15 | Sorrento Therapeutics, Inc. | Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device |
| US20260083777A1 (en) * | 2022-09-19 | 2026-03-26 | Sonoma Biotherapeutics, Inc. | Citrullinated antigen-specific chimeric antigen receptors for targeting regulatory t cells to treat hidradenitis suppurativa |
| CN120813375A (zh) | 2023-01-30 | 2025-10-17 | 凯玛布有限公司 | 抗体 |
| WO2025183487A1 (en) * | 2024-02-29 | 2025-09-04 | Yuhan Corporation | Anti-tigit/anti-pd-l1 bispecific antibody and use thereof |
| CN121175334A (zh) | 2024-04-13 | 2025-12-19 | 益免安协公司 | 在治疗癌症中的使用pd-l1抑制剂的新辅助免疫疗法 |
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| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3817827A (en) | 1972-03-30 | 1974-06-18 | Scott Paper Co | Soft absorbent fibrous webs containing elastomeric bonding material and formed by creping and embossing |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4002531A (en) | 1976-01-22 | 1977-01-11 | Pierce Chemical Company | Modifying enzymes with polyethylene glycol and product produced thereby |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| EP0206448B1 (en) | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US6010902A (en) | 1988-04-04 | 2000-01-04 | Bristol-Meyers Squibb Company | Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity |
| US5766897A (en) | 1990-06-21 | 1998-06-16 | Incyte Pharmaceuticals, Inc. | Cysteine-pegylated proteins |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| JP3051145B2 (ja) | 1990-08-28 | 2000-06-12 | 住友製薬株式会社 | 新規なポリエチレングリコール誘導体修飾ペプチド |
| US5582996A (en) | 1990-12-04 | 1996-12-10 | The Wistar Institute Of Anatomy & Biology | Bifunctional antibodies and method of preparing same |
| DE4118120A1 (de) | 1991-06-03 | 1992-12-10 | Behringwerke Ag | Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US5281698A (en) | 1991-07-23 | 1994-01-25 | Cetus Oncology Corporation | Preparation of an activated polymer ester for protein conjugation |
| US7018809B1 (en) | 1991-09-19 | 2006-03-28 | Genentech, Inc. | Expression of functional antibody fragments |
| JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化ｂ−ｂ１０ |
| JPH07509128A (ja) | 1992-07-13 | 1995-10-12 | バイオネブラスカ・インコーポレーテッド | 組換型ポリペプチドの修飾方法 |
| US5382657A (en) | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
| PT672141E (pt) | 1992-10-23 | 2003-09-30 | Immunex Corp | Metodos de preparacao de proteinas oligomericas soluveis |
| US5446090A (en) | 1993-11-12 | 1995-08-29 | Shearwater Polymers, Inc. | Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
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| US8877688B2 (en) * | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| KR20220084444A (ko) * | 2012-05-31 | 2022-06-21 | 소렌토 쎄라퓨틱스, 인코포레이티드 | Pd-l1에 결합하는 항원 결합 단백질 |
| BR112015007672A2 (pt) * | 2012-10-04 | 2017-08-08 | Dana Farber Cancer Inst Inc | anticorpos anti-pd-l1 monoclonais humanos e métodos de uso |
| AR093984A1 (es) * | 2012-12-21 | 2015-07-01 | Merck Sharp & Dohme | Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano |
| WO2014194302A2 (en) * | 2013-05-31 | 2014-12-04 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind pd-1 |
| CA2944767C (en) | 2014-04-04 | 2022-07-12 | Mayo Foundation For Medical Education And Research | Isotyping immunoglobulins using accurate molecular mass |
| CN105238762A (zh) * | 2015-10-26 | 2016-01-13 | 无锡傲锐东源生物科技有限公司 | 抗pd-1蛋白单克隆抗体杂交瘤细胞及其产生的抗pd-1单克隆抗体和应用 |
| WO2017132562A1 (en) * | 2016-01-29 | 2017-08-03 | Heyue Zhou | Antigen binding proteins that bind pd-l1 |
-
2017
- 2017-01-27 WO PCT/US2017/015429 patent/WO2017132562A1/en not_active Ceased
- 2017-01-27 CN CN201780021396.XA patent/CN109715821B/zh active Active
- 2017-01-27 SG SG11201806496SA patent/SG11201806496SA/en unknown
- 2017-01-27 AU AU2017212717A patent/AU2017212717B2/en active Active
- 2017-01-27 CA CA3013051A patent/CA3013051A1/en active Pending
- 2017-01-27 ES ES17745008T patent/ES2986360T3/es active Active
- 2017-01-27 KR KR1020187024978A patent/KR102927822B1/ko active Active
- 2017-01-27 EA EA201891709A patent/EA037855B1/ru unknown
- 2017-01-27 JP JP2018559164A patent/JP6883590B2/ja active Active
- 2017-01-27 CN CN202210999239.9A patent/CN116333124A/zh active Pending
- 2017-01-27 US US15/418,514 patent/US10118963B2/en active Active
- 2017-01-27 EP EP17745008.7A patent/EP3408400B1/en active Active
- 2017-01-27 BR BR112018015480-6A patent/BR112018015480A2/pt not_active Application Discontinuation
- 2017-01-27 MX MX2018009228A patent/MX2018009228A/es unknown
- 2017-01-27 KR KR1020267004206A patent/KR20260041830A/ko active Pending
- 2017-02-02 TW TW106103519A patent/TWI760323B/zh active
-
2018
- 2018-07-27 MX MX2022011659A patent/MX2022011659A/es unknown
- 2018-07-27 CL CL2018002034A patent/CL2018002034A1/es unknown
- 2018-07-29 IL IL260846A patent/IL260846B2/en unknown
- 2018-07-30 PH PH12018501611A patent/PH12018501611A1/en unknown
- 2018-10-10 US US16/156,895 patent/US10919964B2/en active Active
-
2021
- 2021-01-13 US US17/148,450 patent/US11919952B2/en active Active
- 2021-03-22 JP JP2021047470A patent/JP7140867B2/ja active Active
-
2022
- 2022-04-15 JP JP2022067548A patent/JP2022095910A/ja active Pending
-
2024
- 2024-01-12 US US18/412,102 patent/US20240190959A1/en active Pending
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