|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
GB8620926D0
(en)
|
1986-08-29 |
1986-10-08 |
Delta Biotechnology Ltd |
Yeast promoter
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
CA2441903C
(en)
*
|
2000-05-26 |
2012-07-31 |
National Research Council Of Canada |
Single-domain brain-targeting antibody fragments derived from llama antibodies
|
|
WO2005037867A1
(en)
|
2003-10-15 |
2005-04-28 |
Pdl Biopharma, Inc. |
ALTERATION OF Fc-FUSION PROTEIN SERUM HALF-LIVES BY MUTAGENESIS OF POSITIONS 250, 314 AND/OR 428 OF THE HEAVY CHAIN CONSTANT REGION OF IG
|
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
|
MEP35408A
(en)
|
2005-05-27 |
2011-02-10 |
Biogen Idec Inc |
Tweak binding antibodies
|
|
EP3470072A1
(en)
|
2005-06-23 |
2019-04-17 |
Biogen MA Inc. |
Compositions and methods for modulation of smn2 splicing
|
|
CA2620351C
(en)
|
2005-08-31 |
2015-04-21 |
Universite Laval |
Antibodies and their use in the treatment, prevention and diagnosis of a disease associated with sod1 abnormalities
|
|
US7846445B2
(en)
|
2005-09-27 |
2010-12-07 |
Amunix Operating, Inc. |
Methods for production of unstructured recombinant polymers and uses thereof
|
|
US7855279B2
(en)
|
2005-09-27 |
2010-12-21 |
Amunix Operating, Inc. |
Unstructured recombinant polymers and uses thereof
|
|
WO2008081008A1
(en)
|
2007-01-05 |
2008-07-10 |
University Of Zurich |
Method of providing disease-specific binding molecules and targets
|
|
US8128926B2
(en)
|
2007-01-09 |
2012-03-06 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
|
JP2010536341A
(ja)
|
2007-08-15 |
2010-12-02 |
アムニクス, インコーポレイテッド |
生物学的に活性なポリペプチドの特性を改変するための組成物および方法
|
|
CA2729961C
(en)
*
|
2008-07-09 |
2018-05-01 |
Biogen Idec Ma Inc. |
Li113, li62 variant co2, anti-lingo antibodies
|
|
CN102317316B
(zh)
|
2008-12-19 |
2014-08-13 |
帕尼玛制药股份公司 |
人抗α突触核蛋白自身抗体
|
|
JP2012515556A
(ja)
|
2009-01-23 |
2012-07-12 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
低下したエフェクタ機能を有する安定化Fcポリペプチドおよび使用方法
|
|
US8680050B2
(en)
|
2009-02-03 |
2014-03-25 |
Amunix Operating Inc. |
Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
|
|
ES2610356T3
(es)
|
2009-02-03 |
2017-04-27 |
Amunix Operating Inc. |
Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos
|
|
US8703717B2
(en)
|
2009-02-03 |
2014-04-22 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
|
WO2010144508A1
(en)
|
2009-06-08 |
2010-12-16 |
Amunix Operating Inc. |
Glucose-regulating polypeptides and methods of making and using same
|
|
KR101813727B1
(ko)
|
2009-06-08 |
2018-01-02 |
아뮤닉스 오퍼레이팅 인코포레이티드 |
성장 호르몬 폴리펩타이드 및 이를 제조하고 사용하는 방법
|
|
ES2699827T3
(es)
|
2009-06-17 |
2019-02-13 |
Biogen Ma Inc |
Composiciones y métodos para la modulación de corte y empalme de SMN2 en un sujeto
|
|
CA2771999A1
(en)
|
2009-08-24 |
2011-03-10 |
Amunix Operating Inc. |
Coagulation factor vii compositions and methods of making and using same
|
|
WO2011028344A2
(en)
|
2009-08-25 |
2011-03-10 |
Amunix Operating Inc. |
Interleukin-1 receptor antagonist compositions and methods of making and using same
|
|
EP2493921B1
(en)
|
2009-10-30 |
2018-09-26 |
Albumedix Ltd |
Albumin variants
|
|
KR20130020765A
(ko)
|
2010-02-16 |
2013-02-28 |
메디뮨 엘엘씨 |
Hsa-관련 조성물 및 사용방법
|
|
NZ601117A
(en)
*
|
2010-03-03 |
2014-06-27 |
Boehringer Ingelheim Int |
Biparatopic abeta binding polypeptides
|
|
EP2556087A1
(en)
|
2010-04-09 |
2013-02-13 |
Novozymes Biopharma DK A/S |
Albumin derivatives and variants
|
|
US20130017997A1
(en)
|
2010-08-19 |
2013-01-17 |
Amunix Operating Inc. |
Factor VIII Compositions and Methods of Making and Using Same
|
|
CA2813493C
(en)
|
2010-10-11 |
2019-07-09 |
University Of Zurich |
Human anti-tau antibodies
|
|
US20130225496A1
(en)
|
2010-11-01 |
2013-08-29 |
Novozymes Biopharma Dk A/S |
Albumin Variants
|
|
AU2011343161B2
(en)
|
2010-12-17 |
2017-02-02 |
Neurimmune Holding Ag |
Human anti-SOD1 antibodies
|
|
US9045564B2
(en)
|
2011-02-15 |
2015-06-02 |
Medimmune, Llc |
HSA-related compositions and methods of use
|
|
CN103379915A
(zh)
|
2011-02-15 |
2013-10-30 |
米迪缪尼有限公司 |
Hsa相关组合物及使用方法
|
|
CA2830660A1
(en)
|
2011-05-05 |
2012-11-08 |
Novozymes Biopharma Dk A/S |
Albumin variants
|
|
SI2723379T1
(sl)
|
2011-06-23 |
2019-03-29 |
Biogen International Neuroscience Gmbh |
Molekule, ki se vežejo ma anti alfa-sinuklein
|
|
RU2654567C2
(ru)
|
2011-10-11 |
2018-05-21 |
Дженентек, Инк. |
Улучшенная сборка биспецифических антител
|
|
US9587014B2
(en)
|
2011-10-28 |
2017-03-07 |
Biogen International Neuroscience Gmbh |
TDP-43 specific binding molecules
|
|
US9676849B2
(en)
*
|
2012-01-10 |
2017-06-13 |
Biogen Ma Inc. |
Enhancement of transport of therapeutic molecules across the blood brain barrier
|
|
JP6355563B2
(ja)
|
2012-02-27 |
2018-07-11 |
アムニクス オペレーティング インコーポレイテッド |
Xten共役組成物およびそれを製造する方法
|
|
NZ630542A
(en)
|
2012-08-16 |
2017-06-30 |
Ipierian Inc |
Methods of treating a tauopathy
|
|
CA2896066C
(en)
|
2012-12-21 |
2022-07-12 |
Biogen Ma Inc. |
Human anti-tau antibodies
|
|
US8980270B2
(en)
|
2013-01-18 |
2015-03-17 |
Ipierian, Inc. |
Methods of treating a tauopathy
|
|
US20160033523A1
(en)
|
2013-02-16 |
2016-02-04 |
Novozymes Biopharma Dk A/S |
Pharmacokinetic animal model
|
|
KR102042174B1
(ko)
*
|
2013-03-29 |
2019-11-08 |
삼성전자주식회사 |
인간화 및 친화도 성숙된 항 c-Met 항체 및 그의 용도
|
|
WO2014179657A1
(en)
|
2013-05-03 |
2014-11-06 |
Eleven Biotherapeutics, Inc. |
Albumin variants binding to fcrn
|
|
SG10201902850TA
(en)
|
2014-09-30 |
2019-04-29 |
Neurimmune Holding Ag |
Human-derived anti-dipeptide repeats (dprs) antibody
|
|
ES2924282T3
(es)
*
|
2014-12-19 |
2022-10-05 |
Medimmune Ltd |
Moléculas de transporte a través de la barrera hematoencefálica y usos de las mismas
|
|
US10654917B2
(en)
*
|
2015-01-29 |
2020-05-19 |
Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa |
Antibody molecules and peptide delivery systems for use in alzheimer's disease and related disorders
|
|
WO2017106462A1
(en)
|
2015-12-18 |
2017-06-22 |
Biogen Ma Inc. |
Bispecific antibody platform
|
|
BR112019000220A2
(pt)
*
|
2016-07-06 |
2019-04-24 |
National Research Council Of Canada |
anticorpos humanizados que transmigram a barreira hematoencefálica e usos dos mesmos
|
|
WO2018109663A1
(en)
*
|
2016-12-12 |
2018-06-21 |
National Research Council Of Canada |
Antibody variants transmigrating the blood-brain barrier and uses thereof
|
|
WO2018138709A1
(en)
*
|
2017-01-30 |
2018-08-02 |
National Research Council Of Canada |
Blood-brain barrier transmigrating compounds and uses thereof
|
|
CA3059938A1
(en)
*
|
2017-04-14 |
2018-10-18 |
Kodiak Sciences Inc. |
Complement factor d antagonist antibodies and conjugates thereof
|