JP2022509366A5 - - Google Patents

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Publication number
JP2022509366A5
JP2022509366A5 JP2021547662A JP2021547662A JP2022509366A5 JP 2022509366 A5 JP2022509366 A5 JP 2022509366A5 JP 2021547662 A JP2021547662 A JP 2021547662A JP 2021547662 A JP2021547662 A JP 2021547662A JP 2022509366 A5 JP2022509366 A5 JP 2022509366A5
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JP
Japan
Prior art keywords
optionally substituted
pharmaceutically acceptable
acceptable salt
alkyl
compound according
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JP2021547662A
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English (en)
Japanese (ja)
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JP7503561B2 (ja
JP2022509366A (ja
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Priority claimed from PCT/US2019/057985 external-priority patent/WO2020092139A1/en
Publication of JP2022509366A publication Critical patent/JP2022509366A/ja
Publication of JP2022509366A5 publication Critical patent/JP2022509366A5/ja
Application granted granted Critical
Publication of JP7503561B2 publication Critical patent/JP7503561B2/ja
Active legal-status Critical Current
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JP2021547662A 2018-10-29 2019-10-25 新規ジペプチド化合物及びその使用方法 Active JP7503561B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862751984P 2018-10-29 2018-10-29
US62/751,984 2018-10-29
PCT/US2019/057985 WO2020092139A1 (en) 2018-10-29 2019-10-25 Novel dipeptide compounds and uses thereof

Publications (3)

Publication Number Publication Date
JP2022509366A JP2022509366A (ja) 2022-01-20
JP2022509366A5 true JP2022509366A5 (OSRAM) 2022-10-20
JP7503561B2 JP7503561B2 (ja) 2024-06-20

Family

ID=70464360

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021547662A Active JP7503561B2 (ja) 2018-10-29 2019-10-25 新規ジペプチド化合物及びその使用方法

Country Status (10)

Country Link
US (1) US12209141B2 (OSRAM)
EP (1) EP3873916B8 (OSRAM)
JP (1) JP7503561B2 (OSRAM)
KR (1) KR102882178B1 (OSRAM)
CN (2) CN116813691B (OSRAM)
AU (1) AU2019371209B2 (OSRAM)
CA (1) CA3117599A1 (OSRAM)
IL (1) IL282676B1 (OSRAM)
TW (1) TWI870362B (OSRAM)
WO (1) WO2020092139A1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116813691B (zh) * 2018-10-29 2024-04-12 丽珠医药集团股份有限公司 新的二肽类化合物及其用途
JP2026504578A (ja) * 2023-02-16 2026-02-05 浙江華海薬業股▲フン▼有限公司 ジペプチド類化合物の塩、ならびにその調製方法および使用
CN118496301A (zh) * 2023-02-16 2024-08-16 丽珠医药集团股份有限公司 一种二肽类化合物的盐、其制备方法和用途

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087380A (en) 1949-11-24 2000-07-11 Boehringer Ingelheim Pharma Kg Disubstituted bicyclic heterocycles, the preparations and the use thereof as pharmaceutical compositions
MX9201416A (es) * 1991-03-28 1992-10-01 Rhone Poulenc Rorer Int Peptidos y pseudopeptidos antitromboticos.
JP4561696B2 (ja) 1994-01-27 2010-10-13 三菱化学株式会社 プロリンアミド誘導体
FR2793248B1 (fr) * 1999-05-03 2001-06-29 Adir Nouveaux derives de 2,3-methano-aminoacides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6774110B2 (en) 2001-03-19 2004-08-10 Lg Life Sciences Ltd. Orally available peptidic thrombin inhibitors
FR2836143B1 (fr) 2002-02-21 2004-04-16 Servier Lab Nouveaux derives d'acides amines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20030181488A1 (en) 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
DE10339862A1 (de) 2003-08-29 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel
EP1778616A1 (en) * 2004-08-09 2007-05-02 Cancer Research Technology Limited Alpha-ketoglutarates and their use as therapeutic agents
DE102004062864A1 (de) 2004-12-21 2006-06-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Folienbehälter
CN100502914C (zh) * 2005-10-24 2009-06-24 丽珠医药集团股份有限公司 一种治疗脑中风的中药组合物及其制备方法
KR20080104352A (ko) * 2006-03-29 2008-12-02 쉐링 코포레이션 트롬빈 수용체 길항제로서 유용한 모노사이클릭 및 비사이클릭 힘바신 유도체
EP2152664B1 (en) * 2007-06-13 2014-09-03 Bristol-Myers Squibb Company Dipeptide analogs as coagulation factor inhibitors
TWI513466B (zh) 2010-01-20 2015-12-21 Boehringer Ingelheim Int 抗凝血劑解毒劑
CN102464701B (zh) * 2010-11-08 2015-10-21 上海医药工业研究院 一类新型化合物、其制备方法及用途
CN102796168B (zh) * 2011-05-27 2014-02-26 首都医科大学 一种具有溶血栓活性的化合物,及其制备方法和应用
CN103833827B (zh) * 2012-11-27 2016-08-03 上海医药工业研究院 一种酰胺类化合物、其药物组合物、制备方法及应用
JP6386035B2 (ja) * 2013-06-12 2018-09-05 ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド 金属酵素阻害剤化合物
CN106316975A (zh) * 2015-06-15 2017-01-11 山东轩竹医药科技有限公司 酰胺类化合物及其作为tgr5激动剂的应用
CN116813691B (zh) * 2018-10-29 2024-04-12 丽珠医药集团股份有限公司 新的二肽类化合物及其用途

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