JP2022169718A5 - - Google Patents
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- JP2022169718A5 JP2022169718A5 JP2022134609A JP2022134609A JP2022169718A5 JP 2022169718 A5 JP2022169718 A5 JP 2022169718A5 JP 2022134609 A JP2022134609 A JP 2022134609A JP 2022134609 A JP2022134609 A JP 2022134609A JP 2022169718 A5 JP2022169718 A5 JP 2022169718A5
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- 239000008194 pharmaceutical composition Substances 0.000 claims 19
- 102000010787 Interleukin-4 Receptors Human genes 0.000 claims 17
- 108010038486 Interleukin-4 Receptors Proteins 0.000 claims 17
- 239000005557 antagonist Substances 0.000 claims 16
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 239000003112 inhibitor Substances 0.000 claims 5
- 108010002352 Interleukin-1 Proteins 0.000 claims 3
- 102000000589 Interleukin-1 Human genes 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 2
- 241000238713 Dermatophagoides farinae Species 0.000 claims 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 2
- 239000013566 allergen Substances 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940127212 long-acting beta 2 agonist Drugs 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 102000003390 tumor necrosis factor Human genes 0.000 claims 2
- 241001225321 Aspergillus fumigatus Species 0.000 claims 1
- 241000238657 Blattella germanica Species 0.000 claims 1
- 241000282326 Felis catus Species 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 102000008070 Interferon-gamma Human genes 0.000 claims 1
- 108010074328 Interferon-gamma Proteins 0.000 claims 1
- 108090001007 Interleukin-8 Proteins 0.000 claims 1
- 241000009328 Perro Species 0.000 claims 1
- 206010039094 Rhinitis perennial Diseases 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical group C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
- 208000030961 allergic reaction Diseases 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 229940091771 aspergillus fumigatus Drugs 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229950003468 dupilumab Drugs 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 229940125369 inhaled corticosteroids Drugs 0.000 claims 1
- 229960003130 interferon gamma Drugs 0.000 claims 1
- 208000022719 perennial allergic rhinitis Diseases 0.000 claims 1
- 230000002085 persistent effect Effects 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024137494A JP2024164098A (ja) | 2016-09-01 | 2024-08-19 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662382501P | 2016-09-01 | 2016-09-01 | |
| US62/382,501 | 2016-09-01 | ||
| US201662425726P | 2016-11-23 | 2016-11-23 | |
| US62/425,726 | 2016-11-23 | ||
| PCT/US2017/049538 WO2018045130A1 (en) | 2016-09-01 | 2017-08-31 | Methods for preventing or treating allergy by administering an il-4r antagonist |
| JP2019511889A JP7584218B2 (ja) | 2016-09-01 | 2017-08-31 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511889A Division JP7584218B2 (ja) | 2016-09-01 | 2017-08-31 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024137494A Division JP2024164098A (ja) | 2016-09-01 | 2024-08-19 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022169718A JP2022169718A (ja) | 2022-11-09 |
| JP2022169718A5 true JP2022169718A5 (enExample) | 2023-03-16 |
| JP7542582B2 JP7542582B2 (ja) | 2024-08-30 |
Family
ID=59923551
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511889A Active JP7584218B2 (ja) | 2016-09-01 | 2017-08-31 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
| JP2022134609A Active JP7542582B2 (ja) | 2016-09-01 | 2022-08-26 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
| JP2024137494A Pending JP2024164098A (ja) | 2016-09-01 | 2024-08-19 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511889A Active JP7584218B2 (ja) | 2016-09-01 | 2017-08-31 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024137494A Pending JP2024164098A (ja) | 2016-09-01 | 2024-08-19 | Il-4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11771743B2 (enExample) |
| EP (2) | EP4442323A3 (enExample) |
| JP (3) | JP7584218B2 (enExample) |
| KR (3) | KR102872485B1 (enExample) |
| CN (2) | CN118141914A (enExample) |
| CA (1) | CA3035202A1 (enExample) |
| ES (1) | ES2994774T3 (enExample) |
| HU (1) | HUE067888T2 (enExample) |
| IL (2) | IL265104B2 (enExample) |
| MA (1) | MA46098B1 (enExample) |
| MX (2) | MX2019002344A (enExample) |
| PL (1) | PL3506931T3 (enExample) |
| PT (1) | PT3506931T (enExample) |
| WO (1) | WO2018045130A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| HUE064945T2 (hu) | 2012-08-21 | 2024-04-28 | Sanofi Biotechnology | Eljárások asztma kezelésére vagy megelõzésére IL-4R antagonista beadásával |
| TWI633891B (zh) | 2013-06-04 | 2018-09-01 | 再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| TWI682781B (zh) | 2013-07-11 | 2020-01-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
| RU2704999C2 (ru) | 2014-02-28 | 2019-11-01 | Ридженерон Фармасьютикалз, Инк. | Способ лечения кожной инфекции путем введения антагониста il-4r |
| EP3218412A1 (en) | 2014-11-14 | 2017-09-20 | Sanofi Biotechnology | Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist |
| CN113372446A (zh) | 2016-06-08 | 2021-09-10 | 苏州康乃德生物医药有限公司 | 用于结合白细胞介素4受体的抗体 |
| EP4442323A3 (en) | 2016-09-01 | 2025-01-01 | Regeneron Pharmaceuticals, Inc. | Methods for preventing or treating allergy by administering an il-4r antagonist |
| US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
| MA46269B1 (fr) | 2017-08-18 | 2024-05-31 | Regeneron Pharma | Méthodes de traitement d'une dermatite atopique sévère par administration d'un inhibiteur des il-4r |
| HUE064655T2 (hu) * | 2017-10-30 | 2024-04-28 | Sanofi Biotechnology | IL-4R antagonista asztma kezelésére vagy megelõzésére szolgáló eljárásban |
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| US11312778B2 (en) | 2018-11-21 | 2022-04-26 | Brian C. Machler | Method for treating allergic contact dermatitis |
| CN111518211B (zh) | 2018-12-25 | 2022-06-21 | 江苏荃信生物医药股份有限公司 | 抗人白介素4受体α单克隆抗体的制药用途 |
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| EP4010001A1 (en) | 2019-08-05 | 2022-06-15 | Regeneron Pharmaceuticals, Inc. | Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an il-4r antagonist |
| AU2020326713A1 (en) | 2019-08-05 | 2022-02-17 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r antagonist |
| US11723974B2 (en) | 2019-12-09 | 2023-08-15 | Sanofi-Aventis Biotechnology | Methods for treating digitally identified IL-4/IL-13-related disorders by administering an anti-IL4R-alpha antibody |
| EP3992974A1 (en) | 2020-11-02 | 2022-05-04 | Sanofi Biotechnology | Methods for treating digitally-identified il-4/il-13 related disorders |
| WO2021133776A1 (en) * | 2019-12-23 | 2021-07-01 | Sanofi Biotechnology | Methods for treating or preventing allergic asthma by administering an il-33 antagonist and/or an il-4r antagonist |
| AU2022206434A1 (en) * | 2021-01-08 | 2023-08-24 | Regeneron Pharmaceuticals, Inc. | Methods for treating peanut allergy and enhancing peanut allergen-specific immunotherapy by administering an il-4r antagonist |
| CN114805572B (zh) * | 2021-01-22 | 2022-12-13 | 上海济煜医药科技有限公司 | 抗原结合蛋白及其应用 |
| KR20230111729A (ko) | 2022-01-19 | 2023-07-26 | 연세대학교 원주산학협력단 | 단삼 추출물을 유효성분으로 포함하는 알레르기 질환 예방 또는 치료용 조성물 |
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| US20250230251A1 (en) | 2023-12-20 | 2025-07-17 | Bristol-Myers Squibb Company | Antibodies targeting il-18 receptor beta (il-18rb) and related methods |
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| RU2704999C2 (ru) | 2014-02-28 | 2019-11-01 | Ридженерон Фармасьютикалз, Инк. | Способ лечения кожной инфекции путем введения антагониста il-4r |
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| AU2017332732B2 (en) | 2016-09-22 | 2024-03-14 | Regeneron Pharmaceuticals, Inc. | Methods for treating severe atopic dermatitis by administering an IL-4R inhibitor |
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| WO2018201051A1 (en) | 2017-04-28 | 2018-11-01 | Novartis Ag | Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor |
| US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
| MA46269B1 (fr) | 2017-08-18 | 2024-05-31 | Regeneron Pharma | Méthodes de traitement d'une dermatite atopique sévère par administration d'un inhibiteur des il-4r |
| HUE064655T2 (hu) | 2017-10-30 | 2024-04-28 | Sanofi Biotechnology | IL-4R antagonista asztma kezelésére vagy megelõzésére szolgáló eljárásban |
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| WO2019240288A1 (ja) | 2018-06-14 | 2019-12-19 | 味の素株式会社 | 抗体に対する親和性物質、および生体直交性官能基を有する化合物またはその塩 |
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2017
- 2017-08-31 EP EP24182364.0A patent/EP4442323A3/en active Pending
- 2017-08-31 ES ES17771619T patent/ES2994774T3/es active Active
- 2017-08-31 EP EP17771619.8A patent/EP3506931B1/en active Active
- 2017-08-31 MA MA46098A patent/MA46098B1/fr unknown
- 2017-08-31 KR KR1020227037662A patent/KR102872485B1/ko active Active
- 2017-08-31 HU HUE17771619A patent/HUE067888T2/hu unknown
- 2017-08-31 WO PCT/US2017/049538 patent/WO2018045130A1/en not_active Ceased
- 2017-08-31 CA CA3035202A patent/CA3035202A1/en active Pending
- 2017-08-31 PT PT177716198T patent/PT3506931T/pt unknown
- 2017-08-31 IL IL265104A patent/IL265104B2/en unknown
- 2017-08-31 KR KR1020247014525A patent/KR20240065318A/ko active Pending
- 2017-08-31 MX MX2019002344A patent/MX2019002344A/es unknown
- 2017-08-31 IL IL320424A patent/IL320424A/en unknown
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- 2017-08-31 JP JP2019511889A patent/JP7584218B2/ja active Active
- 2017-08-31 US US16/329,184 patent/US11771743B2/en active Active
- 2017-08-31 CN CN202410243164.0A patent/CN118141914A/zh active Pending
- 2017-08-31 CN CN201780053319.2A patent/CN109789196B/zh active Active
- 2017-08-31 KR KR1020197009282A patent/KR102462039B1/ko active Active
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2019
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2022
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2023
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