PL3613432T3 - Sposoby leczenia polipowatości nosa podawaniem antagonisty il-4r - Google Patents

Sposoby leczenia polipowatości nosa podawaniem antagonisty il-4r

Info

Publication number
PL3613432T3
PL3613432T3 PL19187112.8T PL19187112T PL3613432T3 PL 3613432 T3 PL3613432 T3 PL 3613432T3 PL 19187112 T PL19187112 T PL 19187112T PL 3613432 T3 PL3613432 T3 PL 3613432T3
Authority
PL
Poland
Prior art keywords
polyposity
antagonist
nasal
administration
treatment
Prior art date
Application number
PL19187112.8T
Other languages
English (en)
Inventor
Leda MANNENT
Gianluca Pirozzi
Allen Radin
Namita GANDHI
Robert Evans
Original Assignee
Sanofi Biotechnology
Regeneron Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Biotechnology, Regeneron Pharmaceuticals, Inc. filed Critical Sanofi Biotechnology
Publication of PL3613432T3 publication Critical patent/PL3613432T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
PL19187112.8T 2013-06-21 2014-06-20 Sposoby leczenia polipowatości nosa podawaniem antagonisty il-4r PL3613432T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361837912P 2013-06-21 2013-06-21
EP14305670 2014-05-07

Publications (1)

Publication Number Publication Date
PL3613432T3 true PL3613432T3 (pl) 2026-01-19

Family

ID=50736018

Family Applications (2)

Application Number Title Priority Date Filing Date
PL19187112.8T PL3613432T3 (pl) 2013-06-21 2014-06-20 Sposoby leczenia polipowatości nosa podawaniem antagonisty il-4r
PL14742021T PL3010539T3 (pl) 2013-06-21 2014-06-20 Sposoby leczenia polipowatości nosa przez podawanie antagonisty il-4r

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL14742021T PL3010539T3 (pl) 2013-06-21 2014-06-20 Sposoby leczenia polipowatości nosa przez podawanie antagonisty il-4r

Country Status (20)

Country Link
US (2) US10059771B2 (pl)
EP (3) EP4663250A2 (pl)
JP (1) JP6463351B2 (pl)
KR (3) KR20160024916A (pl)
CN (2) CN111437387B (pl)
AU (4) AU2014284235C1 (pl)
CA (1) CA2915839A1 (pl)
CY (1) CY1122754T1 (pl)
ES (1) ES3050809T3 (pl)
HU (1) HUE073368T2 (pl)
IL (1) IL243246B (pl)
MX (1) MX368068B (pl)
PL (2) PL3613432T3 (pl)
PT (1) PT3613432T (pl)
RS (1) RS59354B1 (pl)
RU (1) RU2674680C2 (pl)
SG (2) SG10201710557QA (pl)
SI (1) SI3010539T1 (pl)
TW (2) TWI709411B (pl)
WO (1) WO2014205365A1 (pl)

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IL315136A (en) 2014-02-21 2024-10-01 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-4rantagonist
PT3613432T (pt) 2014-05-07 2025-10-29 Regeneron Pharma Métodos para tratar a polipose nasal através da administração de um antagonista de il-4r
US10066017B2 (en) 2014-11-14 2018-09-04 Sanofi Biotechnology Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist

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AU2014284235C1 (en) 2025-07-31
TWI709411B (zh) 2020-11-11
AU2025205430A1 (en) 2025-07-31
AU2019261751B2 (en) 2021-11-25
MX368068B (es) 2019-09-18
US20190040146A1 (en) 2019-02-07
CN111437387A (zh) 2020-07-24
EP3613432A1 (en) 2020-02-26
RU2674680C2 (ru) 2018-12-12
IL243246B (en) 2019-09-26
CN111437387B (zh) 2024-10-01
ES3050809T3 (en) 2025-12-23
SG11201509625PA (en) 2015-12-30
IL243246A0 (en) 2016-03-31
AU2019261751A1 (en) 2019-11-28
TW201534325A (zh) 2015-09-16
RU2016101632A (ru) 2017-07-26
AU2014284235B2 (en) 2019-11-21
KR20230066127A (ko) 2023-05-12
SI3010539T1 (sl) 2019-11-29
AU2014284235A1 (en) 2016-01-21
WO2014205365A1 (en) 2014-12-24
JP2016523863A (ja) 2016-08-12
PL3010539T3 (pl) 2020-01-31
TWI757893B (zh) 2022-03-11
AU2022201336A1 (en) 2022-03-24
PT3613432T (pt) 2025-10-29
RS59354B1 (sr) 2019-10-31
CN105517570B (zh) 2020-04-07
MX2015017970A (es) 2016-11-30
HUE073368T2 (hu) 2026-01-28
CY1122754T1 (el) 2021-03-12
CN105517570A (zh) 2016-04-20
KR20160024916A (ko) 2016-03-07
RU2016101632A3 (pl) 2018-05-22
JP6463351B2 (ja) 2019-01-30
CA2915839A1 (en) 2014-12-24
EP3010539A1 (en) 2016-04-27
EP3613432B1 (en) 2025-08-06
US10059771B2 (en) 2018-08-28
EP3010539B1 (en) 2019-07-24
HK1222567A1 (en) 2017-07-07
KR20210132232A (ko) 2021-11-03
US20150017182A1 (en) 2015-01-15
TW202118513A (zh) 2021-05-16
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SG10201710557QA (en) 2018-01-30
AU2022201336B2 (en) 2025-04-17

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