JP2022023958A5 - - Google Patents
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- Publication number
- JP2022023958A5 JP2022023958A5 JP2021178868A JP2021178868A JP2022023958A5 JP 2022023958 A5 JP2022023958 A5 JP 2022023958A5 JP 2021178868 A JP2021178868 A JP 2021178868A JP 2021178868 A JP2021178868 A JP 2021178868A JP 2022023958 A5 JP2022023958 A5 JP 2022023958A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl group
- halogen atom
- hydrogen atom
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020008757 | 2020-01-22 | ||
| JP2020008757 | 2020-01-22 | ||
| PCT/JP2021/002088 WO2021149776A1 (ja) | 2020-01-22 | 2021-01-21 | 抗腫瘍活性を有するアリールアミド誘導体 |
| JP2021536299A JP6971432B1 (ja) | 2020-01-22 | 2021-01-21 | 抗腫瘍活性を有するアリールアミド誘導体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021536299A Division JP6971432B1 (ja) | 2020-01-22 | 2021-01-21 | 抗腫瘍活性を有するアリールアミド誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022023958A JP2022023958A (ja) | 2022-02-08 |
| JP2022023958A5 true JP2022023958A5 (enExample) | 2024-01-30 |
| JP7693513B2 JP7693513B2 (ja) | 2025-06-17 |
Family
ID=76992539
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021536299A Active JP6971432B1 (ja) | 2020-01-22 | 2021-01-21 | 抗腫瘍活性を有するアリールアミド誘導体 |
| JP2021178868A Active JP7693513B2 (ja) | 2020-01-22 | 2021-11-01 | 抗腫瘍活性を有するアリールアミド誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021536299A Active JP6971432B1 (ja) | 2020-01-22 | 2021-01-21 | 抗腫瘍活性を有するアリールアミド誘導体 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11964950B2 (enExample) |
| EP (1) | EP4094804A4 (enExample) |
| JP (2) | JP6971432B1 (enExample) |
| KR (2) | KR20220163514A (enExample) |
| CN (1) | CN114929669B (enExample) |
| AR (1) | AR121078A1 (enExample) |
| AU (1) | AU2021211553A1 (enExample) |
| BR (1) | BR112022009518A2 (enExample) |
| CA (1) | CA3168788A1 (enExample) |
| CL (1) | CL2022001938A1 (enExample) |
| CO (1) | CO2022011429A2 (enExample) |
| CR (1) | CR20220390A (enExample) |
| IL (1) | IL294916A (enExample) |
| MX (1) | MX2022008722A (enExample) |
| PE (1) | PE20230239A1 (enExample) |
| TW (2) | TW202313562A (enExample) |
| WO (1) | WO2021149776A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019306658A1 (en) | 2018-07-20 | 2021-01-07 | F. Hoffmann-La Roche Ag | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
| BR112022013593A2 (pt) | 2020-01-10 | 2022-09-13 | Immuneering Corp | Inibidores de mek e usos terapêuticos dos mesmos |
| AR121078A1 (es) | 2020-01-22 | 2022-04-13 | Chugai Pharmaceutical Co Ltd | Derivados de arilamida con actividad antitumoral |
| WO2022018875A1 (ja) * | 2020-07-22 | 2022-01-27 | 中外製薬株式会社 | アリールアミド誘導体を含む細胞増殖性疾患の治療又は予防用医薬組成物 |
| CR20230095A (es) * | 2020-07-22 | 2023-03-29 | Chugai Pharmaceutical Co Ltd | Composición que contiene un derivado de arilamida |
| WO2022120353A1 (en) | 2020-12-02 | 2022-06-09 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| CA3200814A1 (en) | 2020-12-02 | 2022-06-09 | Alfredo C. Castro | Tead inhibitors and uses thereof |
| EP4281073A1 (en) | 2021-01-25 | 2023-11-29 | Ikena Oncology, Inc. | Combination of a 3-(imidazol-4-yl)-4-(amino)-benzenesulfonamide tead inhibitor with an egfr inhibitor and/or mek inhibitor for use in the treatment of lung cancer |
| CN117677607A (zh) * | 2021-07-21 | 2024-03-08 | 中外制药株式会社 | 芳基酰胺衍生物的制造方法 |
| WO2023114984A1 (en) | 2021-12-17 | 2023-06-22 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| AU2023208566A1 (en) | 2022-01-21 | 2024-07-11 | Chugai Seiyaku Kabushiki Kaisha | Medicine for treating or preventing cancer |
| JP7565132B2 (ja) * | 2022-04-20 | 2024-10-10 | 中外製薬株式会社 | がんの治療又は予防用医薬 |
| WO2024002210A1 (zh) * | 2022-06-30 | 2024-01-04 | 上海喆邺生物科技有限公司 | 一种芳香酰胺类衍生物及其在抗肿瘤药物中的应用 |
| CN120129678A (zh) * | 2022-07-08 | 2025-06-10 | 耐斯泰德医疗公司 | 促分裂原活化蛋白激酶(mek)抑制剂 |
| WO2025007811A1 (zh) * | 2023-07-06 | 2025-01-09 | 成都华健未来科技有限公司 | 一类芳香酰胺类衍生物及其用途 |
| WO2025146040A1 (zh) * | 2024-01-01 | 2025-07-10 | 华健未来（成都）科技股份有限公司 | 芳香酰肼类衍生物及其医药用途 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2594720Y2 (ja) | 1993-03-22 | 1999-05-10 | 株式会社アーテックスズキ | 連結式キャビネット |
| EP1674452A4 (en) | 2003-09-19 | 2007-10-10 | Chugai Pharmaceutical Co Ltd | NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND ITS USE AS MEK INHIBITOR |
| US7732616B2 (en) * | 2003-11-19 | 2010-06-08 | Array Biopharma Inc. | Dihydropyridine and dihydropyridazine derivatives as inhibitors of MEK and methods of use thereof |
| JP4768628B2 (ja) * | 2003-11-19 | 2011-09-07 | アレイ バイオファーマ、インコーポレイテッド | Ｍｅｋの二環系阻害剤及びその使用方法 |
| MY144232A (en) | 2004-07-26 | 2011-08-15 | Chugai Pharmaceutical Co Ltd | 5-substituted-2-phenylamino benzamides as mek inhibitors |
| EP1967516B1 (en) | 2005-05-18 | 2009-11-04 | Array Biopharma, Inc. | 4-(phenylamino)-6-oxo-1,6-dihydropyridazine-3-carboxamide derivatives as MEK inhibitors for the treatment of hyperproliferative diseases |
| AR059339A1 (es) | 2006-02-09 | 2008-03-26 | Chugai Pharmaceutical Co Ltd | Derivados de la cumarina para trastornos proliferativos de celulas, composicion farmaceutica y agente terapeutico que los contiene |
| CN101432281B (zh) * | 2006-04-19 | 2013-08-28 | 诺瓦提斯公司 | 6-0-取代的苯并*唑和苯并噻唑化合物以及抑制csf-1r信号传导的方法 |
| JP5592253B2 (ja) | 2007-05-11 | 2014-09-17 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 過剰増殖性疾患およびマイトジェン細胞外キナーゼ活性関連性疾患を治療するための置換フェニルアミノ−ベンゼン誘導体 |
| CA2720818A1 (en) * | 2008-04-22 | 2009-10-29 | Marion Hitchcock | Substituted phenoxybenzamides |
| EP2346818B1 (en) | 2008-11-10 | 2012-12-05 | Bayer Intellectual Property GmbH | Substituted sulphonamido phenoxybenzamides |
| US9212130B2 (en) | 2010-08-10 | 2015-12-15 | Shionogi & Co., Ltd. | Heterocyclic derivative and pharmaceutical composition comprising the same |
| US20130123255A1 (en) | 2011-11-10 | 2013-05-16 | Chugai Seiyaku Kabushiki Kaisha | Combination of a pi3k inhibitor and a mek inhibitor |
| JP2016034900A (ja) | 2012-11-26 | 2016-03-17 | 中外製薬株式会社 | ５−置換−２−フェニルアミノ−ベンズアミド類の製造方法 |
| EP2968345B1 (en) | 2013-03-13 | 2017-12-13 | The Regents of The University of Michigan | Dual mek/pi3k inhibitors and their application in the treatment of cancer diseases |
| WO2015038417A1 (en) * | 2013-09-10 | 2015-03-19 | Asana Biosciences, Llc | Compounds for regulating fak and/or src pathways |
| KR102222569B1 (ko) | 2013-10-25 | 2021-03-05 | 샹하이 헨그루이 파마수티컬 컴퍼니 리미티드 | 피리딘의 케톤 유도체의 제조 방법 및 제약 용도 |
| CN109988105A (zh) | 2014-01-27 | 2019-07-09 | 天津滨江药物研发有限公司 | 作为蛋白激酶抑制剂的氮杂环类化合物及其制备方法 |
| CN105384738B (zh) | 2014-08-21 | 2017-08-29 | 上海科州药物研发有限公司 | 作为蛋白激酶抑制剂的杂环类化合物及其制备方法和用途 |
| AR121078A1 (es) | 2020-01-22 | 2022-04-13 | Chugai Pharmaceutical Co Ltd | Derivados de arilamida con actividad antitumoral |
| CR20230095A (es) | 2020-07-22 | 2023-03-29 | Chugai Pharmaceutical Co Ltd | Composición que contiene un derivado de arilamida |
-
2021
- 2021-01-20 AR ARP210100120A patent/AR121078A1/es unknown
- 2021-01-21 CA CA3168788A patent/CA3168788A1/en active Pending
- 2021-01-21 KR KR1020227041183A patent/KR20220163514A/ko active Pending
- 2021-01-21 MX MX2022008722A patent/MX2022008722A/es unknown
- 2021-01-21 BR BR112022009518A patent/BR112022009518A2/pt unknown
- 2021-01-21 JP JP2021536299A patent/JP6971432B1/ja active Active
- 2021-01-21 CR CR20220390A patent/CR20220390A/es unknown
- 2021-01-21 PE PE2022001439A patent/PE20230239A1/es unknown
- 2021-01-21 TW TW111146325A patent/TW202313562A/zh unknown
- 2021-01-21 TW TW110102277A patent/TWI788763B/zh active
- 2021-01-21 WO PCT/JP2021/002088 patent/WO2021149776A1/ja not_active Ceased
- 2021-01-21 IL IL294916A patent/IL294916A/en unknown
- 2021-01-21 KR KR1020227002880A patent/KR102473971B1/ko active Active
- 2021-01-21 AU AU2021211553A patent/AU2021211553A1/en active Pending
- 2021-01-21 EP EP21744061.9A patent/EP4094804A4/en active Pending
- 2021-01-21 CN CN202180008024.XA patent/CN114929669B/zh active Active
- 2021-11-01 JP JP2021178868A patent/JP7693513B2/ja active Active
-
2022
- 2022-07-19 CL CL2022001938A patent/CL2022001938A1/es unknown
- 2022-07-20 US US17/869,226 patent/US11964950B2/en active Active
- 2022-08-12 CO CONC2022/0011429A patent/CO2022011429A2/es unknown
-
2024
- 2024-03-18 US US18/608,369 patent/US20240246922A1/en active Pending
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