MX2023014565A - Tratamiento conjunto para tratamiento contra el cancer. - Google Patents
Tratamiento conjunto para tratamiento contra el cancer.Info
- Publication number
- MX2023014565A MX2023014565A MX2023014565A MX2023014565A MX2023014565A MX 2023014565 A MX2023014565 A MX 2023014565A MX 2023014565 A MX2023014565 A MX 2023014565A MX 2023014565 A MX2023014565 A MX 2023014565A MX 2023014565 A MX2023014565 A MX 2023014565A
- Authority
- MX
- Mexico
- Prior art keywords
- combination therapy
- cancer treatment
- cancer
- inhibitor
- directed
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 229940125431 BRAF inhibitor Drugs 0.000 abstract 1
- 229940124647 MEK inhibitor Drugs 0.000 abstract 1
- 239000002829 mitogen activated protein kinase inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere al tratamiento conjunto de cáncer con un inhibidor de BRAF y un inhibidor de MEK, así como a usos y composiciones farmacéuticas de estos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP21178403 | 2021-06-09 | ||
PCT/EP2022/065393 WO2022258612A1 (en) | 2021-06-09 | 2022-06-07 | Combination therapy for cancer treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023014565A true MX2023014565A (es) | 2024-02-08 |
Family
ID=76355323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023014565A MX2023014565A (es) | 2021-06-09 | 2022-06-07 | Tratamiento conjunto para tratamiento contra el cancer. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20240139192A1 (es) |
EP (1) | EP4351577A1 (es) |
KR (2) | KR20240008410A (es) |
CN (1) | CN117642166A (es) |
AU (1) | AU2022288118A1 (es) |
BR (1) | BR112023025916A2 (es) |
CA (1) | CA3222549A1 (es) |
IL (1) | IL307964A (es) |
MX (1) | MX2023014565A (es) |
TW (1) | TW202313046A (es) |
WO (1) | WO2022258612A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20240105382A (ko) * | 2021-11-04 | 2024-07-05 | 에프. 호프만-라 로슈 아게 | 암 치료를 위한 퀴나졸리논 화합물의 신규한 용도 |
US11957759B1 (en) | 2022-09-07 | 2024-04-16 | Arvinas Operations, Inc. | Rapidly accelerated fibrosarcoma (RAF) degrading compounds and associated methods of use |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2275102B1 (en) | 2002-03-13 | 2015-07-29 | Array Biopharma, Inc. | N3 alkylated benzimidazole derivatives as MEK inhibitors |
EP1934174B1 (en) | 2005-10-07 | 2011-04-06 | Exelixis, Inc. | Azetidines as mek inhibitors for the treatment of proliferative diseases |
JO3002B1 (ar) | 2009-08-28 | 2016-09-05 | Irm Llc | مركبات و تركيبات كمثبطات كيناز بروتين |
EP3094627B1 (en) | 2014-01-17 | 2018-08-22 | Novartis AG | 1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and and compositions thereof for inhibiting the activity of shp2 |
JO3517B1 (ar) | 2014-01-17 | 2020-07-05 | Novartis Ag | ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2 |
EP3094629B1 (en) | 2014-01-17 | 2018-08-22 | Novartis AG | 1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions thereof for inhibiting the activity of shp2 |
TW201930292A (zh) | 2017-10-12 | 2019-08-01 | 美商銳新醫藥公司 | 作為變構shp2抑制劑的吡啶、吡嗪和三嗪化合物 |
TWI817018B (zh) * | 2019-06-28 | 2023-10-01 | 美商艾瑞生藥股份有限公司 | 用於治療braf相關的疾病和失調症之化合物 |
WO2021116055A1 (en) * | 2019-12-10 | 2021-06-17 | F. Hoffmann-La Roche Ag | New methylquinazolinone derivatives |
PE20231094A1 (es) * | 2020-07-22 | 2023-07-18 | Chugai Pharmaceutical Co Ltd | Composicion que contiene un derivado de arilamida |
-
2022
- 2022-06-07 MX MX2023014565A patent/MX2023014565A/es unknown
- 2022-06-07 WO PCT/EP2022/065393 patent/WO2022258612A1/en active Application Filing
- 2022-06-07 IL IL307964A patent/IL307964A/en unknown
- 2022-06-07 CA CA3222549A patent/CA3222549A1/en active Pending
- 2022-06-07 CN CN202280041520.XA patent/CN117642166A/zh active Pending
- 2022-06-07 TW TW111121107A patent/TW202313046A/zh unknown
- 2022-06-07 KR KR1020247000499A patent/KR20240008410A/ko active Application Filing
- 2022-06-07 KR KR1020237042276A patent/KR20240005899A/ko active IP Right Grant
- 2022-06-07 AU AU2022288118A patent/AU2022288118A1/en active Pending
- 2022-06-07 BR BR112023025916A patent/BR112023025916A2/pt unknown
- 2022-06-07 EP EP22732509.9A patent/EP4351577A1/en active Pending
-
2023
- 2023-12-08 US US18/533,622 patent/US20240139192A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2022258612A1 (en) | 2022-12-15 |
IL307964A (en) | 2023-12-01 |
AU2022288118A1 (en) | 2023-11-30 |
CA3222549A1 (en) | 2022-12-15 |
CN117642166A (zh) | 2024-03-01 |
BR112023025916A2 (pt) | 2024-02-27 |
EP4351577A1 (en) | 2024-04-17 |
US20240139192A1 (en) | 2024-05-02 |
TW202313046A (zh) | 2023-04-01 |
KR20240005899A (ko) | 2024-01-12 |
KR20240008410A (ko) | 2024-01-18 |
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