JP6971432B1 - 抗腫瘍活性を有するアリールアミド誘導体 - Google Patents

抗腫瘍活性を有するアリールアミド誘導体 Download PDF

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JP6971432B1
JP6971432B1 JP2021536299A JP2021536299A JP6971432B1 JP 6971432 B1 JP6971432 B1 JP 6971432B1 JP 2021536299 A JP2021536299 A JP 2021536299A JP 2021536299 A JP2021536299 A JP 2021536299A JP 6971432 B1 JP6971432 B1 JP 6971432B1
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fluoro
methyl
compound
difluoro
iodoanilino
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JPWO2021149776A1 (enExample
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義明 一色
史郎 渡辺
正樹 富澤
樹人 羽田
一夫 服部
健一 川崎
郁美 兵藤
紀裕 青木
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Chugai Pharmaceutical Co Ltd
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Chugai Pharmaceutical Co Ltd
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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