JP2021527638A5 - - Google Patents
Info
- Publication number
- JP2021527638A5 JP2021527638A5 JP2020568282A JP2020568282A JP2021527638A5 JP 2021527638 A5 JP2021527638 A5 JP 2021527638A5 JP 2020568282 A JP2020568282 A JP 2020568282A JP 2020568282 A JP2020568282 A JP 2020568282A JP 2021527638 A5 JP2021527638 A5 JP 2021527638A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- heterocycloalkyl
- heteroaryl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862683557P | 2018-06-11 | 2018-06-11 | |
| US62/683,557 | 2018-06-11 | ||
| US201962832734P | 2019-04-11 | 2019-04-11 | |
| US62/832,734 | 2019-04-11 | ||
| PCT/US2019/036611 WO2019241292A1 (en) | 2018-06-11 | 2019-06-11 | Hepatitis b capsid assembly modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021527638A JP2021527638A (ja) | 2021-10-14 |
| JP2021527638A5 true JP2021527638A5 (enExample) | 2022-06-17 |
Family
ID=68765513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020568282A Pending JP2021527638A (ja) | 2018-06-11 | 2019-06-11 | Ｂ型肝炎カプシドアセンブリモジュレーター |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US10590076B2 (enExample) |
| EP (1) | EP3807246A4 (enExample) |
| JP (1) | JP2021527638A (enExample) |
| KR (1) | KR20210019489A (enExample) |
| CN (1) | CN112585118A (enExample) |
| AU (1) | AU2019284617A1 (enExample) |
| BR (1) | BR112020025073A2 (enExample) |
| CA (1) | CA3102972A1 (enExample) |
| DE (1) | DE202019005471U1 (enExample) |
| GB (1) | GB2583614B (enExample) |
| IL (1) | IL279242A (enExample) |
| PH (1) | PH12020552127A1 (enExample) |
| SG (1) | SG11202012346YA (enExample) |
| TW (1) | TW202016073A (enExample) |
| WO (1) | WO2019241292A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2943204B1 (en) | 2013-01-10 | 2019-03-13 | Venatorx Pharmaceuticals Inc | Beta-lactamase inhibitors |
| PT3154989T (pt) | 2014-06-11 | 2021-05-18 | Venatorx Pharmaceuticals Inc | Inibidores de beta-lactamase |
| WO2019118358A1 (en) | 2017-12-11 | 2019-06-20 | VenatoRx Pharmaceuticals, Inc. | Hepatitis b capsid assembly modulators |
| WO2019185016A1 (zh) | 2018-03-30 | 2019-10-03 | 正大天晴药业集团股份有限公司 | 含有n杂五元环的衣壳蛋白装配抑制剂、其药物组合物和用途 |
| CN113549079A (zh) * | 2018-05-25 | 2021-10-26 | 正大天晴药业集团股份有限公司 | 2,3-二氢-1h-吡咯嗪-7-甲酰胺类衍生物及其应用 |
| JP2021527638A (ja) | 2018-06-11 | 2021-10-14 | ベナトルクス ファーマシューティカルズ，インク． | Ｂ型肝炎カプシドアセンブリモジュレーター |
| US20230056135A1 (en) * | 2018-10-05 | 2023-02-23 | Emory University | Monomer and multimeric anti-hbv agents |
| EA202092159A1 (ru) * | 2019-01-25 | 2020-12-15 | Чиа Тай Тянцин Фармасьютикал Груп Ко., Лтд. | Содержащий n-гетероциклическое пятичленное кольцо ингибитор сборки капсидного белка, его фармацевтическая композиция и их применение |
| CN113365999B (zh) * | 2019-01-31 | 2023-04-14 | 正大天晴药业集团股份有限公司 | 含有吡咯并杂环的衣壳蛋白装配抑制剂 |
| US12384745B2 (en) | 2019-09-29 | 2025-08-12 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Crystal form of five-membered n heterocyclic compound, and application thereof |
| AU2020355384B2 (en) * | 2019-09-29 | 2025-12-18 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Crystalline form of capsid protein assembly inhibitor containing N hetero five-membered ring, and application thereof |
| EP4245372A3 (en) * | 2019-11-13 | 2023-11-22 | Xi'An Xintong Pharmaceutical Research Co., Ltd. | Hbv inhibitor and use thereof |
| US20230107941A1 (en) * | 2019-12-10 | 2023-04-06 | VenatoRx Pharmaceuticals, Inc. | Hepatitis b capsid assembly modulators |
| WO2021178362A1 (en) * | 2020-03-03 | 2021-09-10 | VenatoRx Pharmaceuticals, Inc. | Hepatitis b capsid assembly modulators |
| CN113493441B (zh) * | 2020-04-03 | 2024-07-09 | 广东东阳光药业股份有限公司 | 新型螺环类化合物及其在药物中的应用 |
| WO2023056933A1 (zh) | 2021-10-08 | 2023-04-13 | 正大天晴药业集团股份有限公司 | 包含衣壳蛋白抑制剂和逆转录酶抑制剂的药物组合 |
| CN119173508B (zh) * | 2023-01-12 | 2025-11-04 | 成都微芯药业有限公司 | 氨基噻吩类化合物、其制备方法及用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1059007A (en) | 1912-05-21 | 1913-04-15 | Benjamin F Sharp | Electrical burglar-alarm. |
| JP2005060379A (ja) * | 2003-07-31 | 2005-03-10 | Dainippon Pharmaceut Co Ltd | 複素環式化合物からなる医薬 |
| CN101103032B (zh) | 2004-12-24 | 2011-05-11 | 大日本住友制药株式会社 | 双环吡咯衍生物 |
| CA2635209A1 (en) | 2006-01-12 | 2007-08-02 | Merck & Co., Inc. | Fluorinated arylamide derivatives |
| JP5977347B2 (ja) * | 2011-07-01 | 2016-08-24 | バルーク エス．ブルームバーグ インスティテュート | Ｈｂｖ感染に対する抗ウイルス剤としてのスルファモイルベンズアミド誘導体 |
| BR112014015197A8 (pt) | 2011-12-21 | 2017-06-13 | Novira Therapeutics Inc | agentes antivirais de hepatite b |
| HRP20180791T1 (hr) * | 2013-07-25 | 2018-09-07 | Janssen Sciences Ireland Uc | Glioksamid supstituirani derivati pirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b |
| CA2923712C (en) * | 2013-10-23 | 2021-11-02 | Janssen Sciences Ireland Uc | Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| TW201620893A (zh) * | 2014-02-06 | 2016-06-16 | 健生科學愛爾蘭無限公司 | 磺醯胺基吡咯醯胺衍生物及其用作治療ｂ型肝炎之醫藥品的用途 |
| US10875876B2 (en) | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| CO2018009382A2 (es) * | 2016-03-09 | 2018-09-20 | Univ Emory | Eliminación del virus de la hepatitis b con agentes antivirales |
| JOP20190024A1 (ar) * | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| CN108250121A (zh) * | 2016-12-28 | 2018-07-06 | 上海长森药业有限公司 | 磺酰胺-芳基酰胺类化合物及其治疗乙型肝炎的药物用途 |
| WO2019118358A1 (en) | 2017-12-11 | 2019-06-20 | VenatoRx Pharmaceuticals, Inc. | Hepatitis b capsid assembly modulators |
| JP7050165B2 (ja) * | 2018-02-26 | 2022-04-07 | ギリアード サイエンシーズ， インコーポレイテッド | Ｈｂｖ複製阻害剤としての置換ピロリジン化合物 |
| WO2019185016A1 (zh) * | 2018-03-30 | 2019-10-03 | 正大天晴药业集团股份有限公司 | 含有n杂五元环的衣壳蛋白装配抑制剂、其药物组合物和用途 |
| CN113549079A (zh) | 2018-05-25 | 2021-10-26 | 正大天晴药业集团股份有限公司 | 2,3-二氢-1h-吡咯嗪-7-甲酰胺类衍生物及其应用 |
| JP2021527638A (ja) | 2018-06-11 | 2021-10-14 | ベナトルクス ファーマシューティカルズ，インク． | Ｂ型肝炎カプシドアセンブリモジュレーター |
| CN113365999B (zh) | 2019-01-31 | 2023-04-14 | 正大天晴药业集团股份有限公司 | 含有吡咯并杂环的衣壳蛋白装配抑制剂 |
| US12384745B2 (en) | 2019-09-29 | 2025-08-12 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Crystal form of five-membered n heterocyclic compound, and application thereof |
| AU2020355384B2 (en) | 2019-09-29 | 2025-12-18 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Crystalline form of capsid protein assembly inhibitor containing N hetero five-membered ring, and application thereof |
| CN114728973B (zh) | 2019-11-22 | 2024-06-28 | 正大天晴药业集团股份有限公司 | 一种核蛋白抑制剂的晶型及其应用 |
| US20230107941A1 (en) | 2019-12-10 | 2023-04-06 | VenatoRx Pharmaceuticals, Inc. | Hepatitis b capsid assembly modulators |
| WO2021178362A1 (en) | 2020-03-03 | 2021-09-10 | VenatoRx Pharmaceuticals, Inc. | Hepatitis b capsid assembly modulators |
| WO2022095950A1 (zh) | 2020-11-05 | 2022-05-12 | 正大天晴药业集团股份有限公司 | 包含衣壳蛋白抑制剂和核苷类似物的药物组合 |
-
2019
- 2019-06-11 JP JP2020568282A patent/JP2021527638A/ja active Pending
- 2019-06-11 GB GB2010185.3A patent/GB2583614B/en active Active
- 2019-06-11 SG SG11202012346YA patent/SG11202012346YA/en unknown
- 2019-06-11 WO PCT/US2019/036611 patent/WO2019241292A1/en not_active Ceased
- 2019-06-11 CA CA3102972A patent/CA3102972A1/en active Pending
- 2019-06-11 KR KR1020217000251A patent/KR20210019489A/ko not_active Ceased
- 2019-06-11 TW TW108120145A patent/TW202016073A/zh unknown
- 2019-06-11 BR BR112020025073-2A patent/BR112020025073A2/pt not_active Application Discontinuation
- 2019-06-11 AU AU2019284617A patent/AU2019284617A1/en not_active Abandoned
- 2019-06-11 US US16/438,361 patent/US10590076B2/en active Active
- 2019-06-11 CN CN201980054009.1A patent/CN112585118A/zh active Pending
- 2019-06-11 EP EP19819142.1A patent/EP3807246A4/en not_active Withdrawn
- 2019-06-11 DE DE202019005471.5U patent/DE202019005471U1/de active Active
- 2019-11-01 US US16/671,815 patent/US11014881B2/en not_active Expired - Fee Related
-
2020
- 2020-12-06 IL IL279242A patent/IL279242A/en unknown
- 2020-12-10 PH PH12020552127A patent/PH12020552127A1/en unknown
-
2021
- 2021-10-29 US US17/514,578 patent/US11566001B2/en active Active
-
2022
- 2022-09-19 US US17/947,593 patent/US20230062975A1/en not_active Abandoned
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